Angiogenesis And Cardiovascular Disease

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Angiogenesis and Cardiovascular Disease

Author : J. Anthony Ware
Publisher :
ISBN 13 : 9780195112351
Total Pages : 384 pages
Book Rating : 4.1/5 (123 download)

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Book Synopsis Angiogenesis and Cardiovascular Disease by : J. Anthony Ware

Download or read book Angiogenesis and Cardiovascular Disease written by J. Anthony Ware and published by . This book was released on 1999 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis and Cardiovascular Disease provides a comprehensive review of the basic scientific and clinical advances in the field of angiogenesis, and its role in the human cardiovascular system. The material presented draws from multiple disciplines, integrating information in a singlesource. Topics addressed focus first on aspects of development and normal biology of the vasculature, and then on angiogenesis and how it is involved in the pathophysiology and therapy of ischemic cardiovascular disease. Vascular development, endothelial cell biology, the vascular matrix, and growthfactors are discussed. Up to date information on current clinical trials, and practical advice concerning application to cardiovascular therapeutic options, are also stressed.

New Vessels for the Heart

Author : Thomas Joseph Stegmann
Publisher : Cardiovascular Biotherapeutics Incorporated
ISBN 13 : 9780976558309
Total Pages : 138 pages
Book Rating : 4.5/5 (583 download)

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Book Synopsis New Vessels for the Heart by : Thomas Joseph Stegmann

Download or read book New Vessels for the Heart written by Thomas Joseph Stegmann and published by Cardiovascular Biotherapeutics Incorporated. This book was released on 2005 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physiologic and Pathologic Angiogenesis

Author : Dan Simionescu
Publisher : BoD – Books on Demand
ISBN 13 : 9535130234
Total Pages : 466 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Physiologic and Pathologic Angiogenesis by : Dan Simionescu

Download or read book Physiologic and Pathologic Angiogenesis written by Dan Simionescu and published by BoD – Books on Demand. This book was released on 2017-04-05 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Angiogenesis and Direct Myocardial Revascularization

Author : Roger J. Laham
Publisher : Springer Science & Business Media
ISBN 13 : 1592599346
Total Pages : 372 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Angiogenesis and Direct Myocardial Revascularization by : Roger J. Laham

Download or read book Angiogenesis and Direct Myocardial Revascularization written by Roger J. Laham and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.

Biochemical Basis and Therapeutic Implications of Angiogenesis

Author : Jawahar Mehta
Publisher : Springer Science & Business Media
ISBN 13 : 1461458579
Total Pages : 536 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Biochemical Basis and Therapeutic Implications of Angiogenesis by : Jawahar Mehta

Download or read book Biochemical Basis and Therapeutic Implications of Angiogenesis written by Jawahar Mehta and published by Springer Science & Business Media. This book was released on 2013-03-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body. It plays a critical role in both physiological processes such as growth and development as well as pathological processes including cancer and different types of tumors. Angiogenesis is also essential for the regeneration and survival of cells in several disease conditions such as ischemic heart disease (myocardial infarction), atherosclerosis, brain injury (stroke) and diabetes. Since the mechanisms of angiogenesis are organ specific and differ among various diseases, it is proposed to devote one section of this book to the development of angiogenesis in some selected diseases such as cancer, ischemic heart disease, atherosclerosis, diabetes and stroke. It is pointed out that extensive research work in this regard has been carried out in the area of cancer and heart disease, whereas relatively less attention has been paid to studying angiogenesis in other disease conditions.

Angiogenesis and Vascularisation

Author : Józef Dulak
Publisher : Springer Science & Business Media
ISBN 13 : 3709114284
Total Pages : 414 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Angiogenesis and Vascularisation by : Józef Dulak

Download or read book Angiogenesis and Vascularisation written by Józef Dulak and published by Springer Science & Business Media. This book was released on 2014-02-10 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the overview of the current knowledge in some fields of vascular biology, addressing cellular and molecular aspects of blood-vessel formation and their role in health and disease. The major factors involved in the formation of blood vessels are presented by scientists actively involved in this area of research. Special emphasis is put on the presentation of various molecular mechanisms not addressed in similar works to date. The book is divided into three parts. The first part describes the cells and mediators in angiogenesis. The significance of various populations of potential endothelial progenitors is particularly highlighted. The chapters of the second part focus on molecular mechanisms, with special emphasis on the role of hypoxia, gasotransmitters and reactive oxygen species as well as microRNAs in regulation of angiogenic processes. In the third part, the pathological aspects of disturbed – aggravated or impaired – vascularization are discussed and new modalities for potential therapies are presented. The book is intended for scientists and PhD students in the fields of vascular biology and cancer research. It may be of interest for medical professionals in the fields of cardiovascular disease, diabetes, oncology and rheumatoid arthritis.

Cardiovascular Genomics

Author : Mohan K. Raizada
Publisher : Springer Science & Business Media
ISBN 13 : 1592598838
Total Pages : 367 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Cardiovascular Genomics by : Mohan K. Raizada

Download or read book Cardiovascular Genomics written by Mohan K. Raizada and published by Springer Science & Business Media. This book was released on 2008-02-24 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

Coronary Heart Disease

Author : Zeev Vlodaver
Publisher : Springer Science & Business Media
ISBN 13 : 146141475X
Total Pages : 543 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Coronary Heart Disease by : Zeev Vlodaver

Download or read book Coronary Heart Disease written by Zeev Vlodaver and published by Springer Science & Business Media. This book was released on 2012-01-07 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary Heart Disease: Clinical, Pathological, Imaging, and Molecular Profiles presents a comprehensive picture of ischemic heart disease for practitioners, students, and investigators dealing with the varied facets of this complex subject. Individual chapters introduce the anatomy of the coronary blood vessels and cardiac development, while others consider current imaging modalities utilized for ischemic heart disease, including stress echo, nuclear diagnostic tests, non-invasive coronary artery imaging, and coronary angiography. Imaging chapters provide key clinical information on techniques and indications, and include examples of both normal and abnormal patterns. The principle thrust of the book concerns coronary atherosclerosis, the pathology of which is presented in conjunction with the results of anatomic, non-invasive imaging and angiographic studies. Related chapters cover atherogenesis, presenting new insights into the pathophysiology of the vulnerable plaque, the role of progenitor cells in vascular injury, inflammation and atherogenesis, and the genomics of vascular remodeling. Additional topics covered include angina pectoris, acute coronary syndromes, healed myocardial infarction and congestive heart failure, catheter-based and surgical revascularization, and surgical treatment of myocardial infarction and its sequelae. With contributions from a diverse group of internationally-known physicians with broad experience in the diagnosis and treatment of coronary heart disease, this book will be a valuable resource for practitioners in clinical cardiology, thoracic surgery, pathology, and cardiovascular molecular research, as well as for students in training.

Biochemical Basis and Therapeutic Implications of Angiogenesis

Author : Jawahar L. Mehta
Publisher : Springer
ISBN 13 : 3319611151
Total Pages : 548 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Biochemical Basis and Therapeutic Implications of Angiogenesis by : Jawahar L. Mehta

Download or read book Biochemical Basis and Therapeutic Implications of Angiogenesis written by Jawahar L. Mehta and published by Springer. This book was released on 2017-08-28 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis’ role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease. The book is comprehensive in its coverage of angiogenesis in a diverse set of diseases and examines the role of cellular and subcellular structures during the development of angiogenesis. Well-organized and thorough, this is an ideal book for researchers and biomedical engineers working in the field of therapeutic implications of angiogenesis. This book also: Covers the basics of the physiology of angiogenesis, including VEGF pathways in angiogenesis, integr ins in angiogenesis, angiogenesis and exercise physiology, and more Details the role of angiogenesis in atherosclerosis and heart disease, including vascular endothelial growth factor and atherosclerotic plaque progression as well as angiogenesis and heart failure Illustrates in detail brain angiogenesis after stroke and the relationship between angiogenesis and Alzheimer's disease

Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases

Author : Rory R. Koenen
Publisher : Frontiers Media SA
ISBN 13 : 288945620X
Total Pages : 118 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases by : Rory R. Koenen

Download or read book Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases written by Rory R. Koenen and published by Frontiers Media SA. This book was released on 2018-10-19 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology.

Inflammation and the Microcirculation

Author : D. Neil Granger
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041656
Total Pages : 99 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger

Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Applications of Biotechnology in Cardiovascular Therapeutics

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
ISBN 13 : 1617792403
Total Pages : 376 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Applications of Biotechnology in Cardiovascular Therapeutics by : Kewal K. Jain

Download or read book Applications of Biotechnology in Cardiovascular Therapeutics written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2011-07-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.

Endothelial Dysfunction

Author : Helena Lenasi
Publisher : BoD – Books on Demand
ISBN 13 : 1789842530
Total Pages : 432 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Endothelial Dysfunction by : Helena Lenasi

Download or read book Endothelial Dysfunction written by Helena Lenasi and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.

Cardiovascular Research

Author : Gerard Pasterkamp
Publisher : Springer Science & Business Media
ISBN 13 : 0387233296
Total Pages : 261 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Cardiovascular Research by : Gerard Pasterkamp

Download or read book Cardiovascular Research written by Gerard Pasterkamp and published by Springer Science & Business Media. This book was released on 2007-06-10 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, technical improvements have changed the inventory of many research laboratories. New techniques and discoveries continuously give rise to observations that result in the de?nition of new research objectives. In the past, - search departments were clearly demarcated. Nowadays, technology that is shared by all lines of research stimulates convergence of research interests. This also - plies to cardiovascular research. Vascular occlusive disease is now core business for researchers employed by cardiology, vascular surgery, vascular medicine, - diology, cell biology, chemistry, physiology, and many other areas. Knowledge on actual research development is shared by researchers with different skills. It is sometimes dif?cult to acquire expertise when a researcher feels his experimental work could be improved by introducing a new research technique. In this book, the investigator will ?nd an overview of recent developments that are relevant for research in general but cardiovascular research in particular. Genomics, p- teomics, microarray, RNAi, stem cells, and progenitor cells are just some phrases that have become increasingly prevalent in literature in the last few years and that are recognized by many, but are fully understood by few. In this book, experts share the most appreciated new developments and techniques in cardiovascular research. We hope that this book will help the reader who is working in the ?eld of cardiovascular research to understand and critically appreciate current research, and that it will help improve the quality of experimental work. Dr G.

Coronary Artery Disease

Author : Gregory W. Barsness
Publisher : Springer Science & Business Media
ISBN 13 : 1846284600
Total Pages : 196 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Coronary Artery Disease by : Gregory W. Barsness

Download or read book Coronary Artery Disease written by Gregory W. Barsness and published by Springer Science & Business Media. This book was released on 2011-12-07 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: A book directed towards individuals with an interest in the clinical treatment of patients with unrevascularizable angina. It explores the treatment options in the setting of a sound scientific background and provides guidance and predictions for future directions in this rapidly developing field. It is the only textbook of its kind and fulfils an unmet need for practicing internal medicine, family practice and cardiovascular clinicians. It also provides a reliable reference for clinical and basic researchers interested in this topic.

The ESC Textbook of Vascular Biology

Author : Rob Krams
Publisher : Oxford University Press
ISBN 13 : 0198755775
Total Pages : 347 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis The ESC Textbook of Vascular Biology by : Rob Krams

Download or read book The ESC Textbook of Vascular Biology written by Rob Krams and published by Oxford University Press. This book was released on 2017 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Textbook of Vascular Biology is a rich and clearly laid-out guide by leading European scientists providing comprehensive information on vascular physiology, disease, and research.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.