Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Amphioxus Immunity
Download Amphioxus Immunity full books in PDF, epub, and Kindle. Read online Amphioxus Immunity ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Download or read book Amphioxus Immunity written by An-Long Xu and published by Elsevier. This book was released on 2015-12-31 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as: Amphioxus as a model for understanding the evolution of vertebrates basic knowledge of immunology immune organs and cells of amphioxus a genomic and transcriptomic view of the Amphioxus immunity pattern recognition system in Amphioxus transcription factors in Amphioxus the complement system of Amphioxus the oxidative burst system in Amphioxus immune effectors in Amphioxus lipid signaling of immune response in Amphioxus apoptosis in amphioxus; primitive adaptive immune system of Amphioxus and future research directions This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity. Provides new evidence on the origin of the adaptive immune system, the evolution of innate immunity, and evolution-stage specific immune defense mechanisms Not only presents the cells and molecules involved in the adaptive immune response in Amphioxus, but also characterizes the origination and evolution of the gene families and pathways involved in innate immunity Includes much pioneering work, from the molecular, genomic, and cellular to the individual level
Download or read book Amphioxus Immunity written by Anlong Xu and published by . This book was released on 2011 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Comparative Immunology by : Edwin L. Cooper
Download or read book Advances in Comparative Immunology written by Edwin L. Cooper and published by Springer. This book was released on 2018-08-07 with total page 1048 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.
Book Synopsis Evolution of Innate Immunity in Eukarya: Advances and Implications by : Jean L. Scholz
Download or read book Evolution of Innate Immunity in Eukarya: Advances and Implications written by Jean L. Scholz and published by Frontiers Media SA. This book was released on 2022-05-06 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Issues in Immunology Research: 2011 Edition by :
Download or read book Issues in Immunology Research: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1988 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Immunology Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunology Research. The editors have built Issues in Immunology Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunology Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book The M2 Macrophage written by Tamás Röszer and published by Springer Nature. This book was released on 2020-08-03 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.
Book Synopsis Issues in Immunology Research: 2012 Edition by :
Download or read book Issues in Immunology Research: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2013-01-10 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Immunology Research / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunogenetics. The editors have built Issues in Immunology Research: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunogenetics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Changing Views of the Evolution of Immunity by : Gary W. Litman
Download or read book Changing Views of the Evolution of Immunity written by Gary W. Litman and published by Frontiers E-books. This book was released on 2014-01-22 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The multitude of cells, signaling pathways, receptors, novel genetic recombination mechanisms and interactive pathways of receptor function and cell differentiation that constitute the vertebrate adaptive immune system are integrally linked with the multicomponent innate immune system. At first glance, the levels of complexity seen in both systems at the phylogenetic level of mammals present what seem to be insurmountable hurdles in terms of achieving a systematic understanding of the evolution of immunity. New research directions and approaches suggest that resolution of many long-standing questions in this area is now possible. Historically, immunologists considered lower vertebrates and invertebrates as “simpler” forms, i.e., they were expected to possess more basic (less layered) levels of immunological complexity and thus potentially would serve as important resources. By considering the systematic placement of representative species in the context of phylogeny, characterizing their immune receptors, co-receptors as well as accessory molecules and evaluating responses to immunologic stimuli, it was thought that a clearer picture of immune evolution would emerge. There is no doubt that this approach has achieved some notable successes but for the most part it has fallen short in terms of achieving a broad understanding of the immunologic needs of many relevant models and how adaptive change in immune function is effected. Even if a structurally relevant ortholog of an immune effector is identified in a model organism, there is no reason to assume that it functions in a corresponding manner in disparate phylogenetic taxa. For example, survival of a sessile marine invertebrate, whose anatomical form puts it in open and contiguous contact with a literal sea of microorganisms and viruses, would be thought to depend, at least in part, on a “capable” immune response; however, at present, we have no real understanding of how this is achieved in an integrated manner. Furthermore, questions arise as to whether or not phenomena that are considered integral components of vertebrate-type immunity such as memory, tolerance, somatic change and clonal selection exist in invertebrates and if their functions parallel those recognized in mammals. More often than not, our interpretations are guided by preconceived notions that are based on observations made in distant species that often do not apply to far- removed taxa. We anticipate that major advances in our understanding of this broad subject are now forthcoming as resources exist or are being developed for examining important model organisms in their natural environments instead of within the confines of in vitro systems of potentially remote physiological significance. Taking a wide range of hypotheses, observations and interpretations into account, in this special topic, contributors have developed a comprehensive overview emphasizing new directions and interpretations for understanding basic aspects of immunity that consider unique features inherent to various model systems, their life histories and habitats. Approaches applied with key model organisms maintained and confronted with relevant challenges under natural conditions are emphasized. Current concepts of self and nonself are addressed not only in terms of immunity but also reproductive fitness. How genetic variation in immune effector molecules is achieved and maintained in natural populations is examined; particular attention is directed to response interfaces that factor in symbiotic interactions. Gene expansion and mechanisms of genetic diversification are explored. How diverse molecules and a variety of effector cells contribute to our broad understanding of the evolution of a remarkably complex, integrated system and how this work is facilitating our understanding of mammalian immunity is addressed.
Book Synopsis Invertebrate Pathology by : Andrew F. Rowley
Download or read book Invertebrate Pathology written by Andrew F. Rowley and published by Oxford University Press. This book was released on 2022-02-07 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many invertebrates are serious pests of agriculture (e.g., mites and locusts), vectors of disease (e.g., mosquitoes and aquatic snails) and venomous (e.g., scorpions), whilst others are beneficial to humans as pollinators, food sources, and detritivores. Despite their obvious ecological, medical, and economic importance, this is the first comprehensive review of invertebrate diseases to be available within a single volume. Concurrent molecular and bioinformatics developments over the last decade have catalysed a renaissance in invertebrate pathology. High-throughput sequencing, handheld diagnostic kits, and the move to new technologies have rapidly increased our understanding of invertebrate diseases, generating a large volume of fundamental and applied research on the topic. An overview is now timely and this authoritative work assembles an international team of the leading specialists in the field to review the main diseases and pathologic manifestations of all the major invertebrate groups. Each chapter adopts a common plan in terms of its scope and approach to achieve a succinct and coherent synthesis. Invertebrate Pathology is aimed at graduate students and researchers in the fields of disease ecology, invertebrate biology, comparative immunology, aquaculture, fisheries, veterinary science, evolution, and conservation. It will be particularly useful for readers new to the field as well as a broader interdisciplinary audience of practitioners and resource managers.
Book Synopsis The Evolution of the Immune System by : Davide Malagoli
Download or read book The Evolution of the Immune System written by Davide Malagoli and published by Academic Press. This book was released on 2016-07-21 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership
Book Synopsis Handbook of Marine Model Organisms in Experimental Biology by : Agnes Boutet
Download or read book Handbook of Marine Model Organisms in Experimental Biology written by Agnes Boutet and published by CRC Press. This book was released on 2021-12-13 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of molecular approaches for comparative biology and the rapid development of new molecular tools is unprecedented. The extraordinary molecular progress belies the need for understanding the development and basic biology of whole organisms. Vigorous international efforts to train the next-generation of experimental biologists must combine both levels – next generation molecular approaches and traditional organismal biology. This book provides cutting-edge chapters regarding the growing list of marine model organisms. Access to and practical advice on these model organisms have become a conditio sine qua non for a modern education of advanced undergraduate students, graduate students and postdocs working on marine model systems. Model organisms are not only tools they are also bridges between fields – from behavior, development and physiology to functional genomics. Key Features Offers deep insights into cutting-edge model system science Provides in-depth overviews of all prominent marine model organisms Illustrates challenging experimental approaches to model system research Serves as a reference book also for next-generation functional genomics applications Fills an urgent need for students Related Titles Jarret, R. L. & K. McCluskey, eds. The Biological Resources of Model Organisms (ISBN 978-1-1382-9461-5) Kim, S.-K. Healthcare Using Marine Organisms (ISBN 978-1-1382-9538-4) Mudher, A. & T. Newman, eds. Drosophila: A Toolbox for the Study of Neurodegenerative Disease (ISBN 978-0-4154-1185-1) Green, S. L. The Laboratory Xenopus sp. (ISBN 978-1-4200-9109-0)
Book Synopsis Physiology; general pathology; general therapeutics; immunity by : Charles Eucharist de Medicis Sajous
Download or read book Physiology; general pathology; general therapeutics; immunity written by Charles Eucharist de Medicis Sajous and published by . This book was released on 1903 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Phosphotransferases (Nitrogenous Group Acceptor) Research and Application: 2013 Edition by :
Download or read book Advances in Phosphotransferases (Nitrogenous Group Acceptor) Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Phosphotransferases (Nitrogenous Group Acceptor) Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Creatine Kinase in a concise format. The editors have built Advances in Phosphotransferases (Nitrogenous Group Acceptor) Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Creatine Kinase in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Phosphotransferases (Nitrogenous Group Acceptor) Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Bacterial Antigens—Advances in Research and Application: 2013 Edition by :
Download or read book Bacterial Antigens—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Antigens—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Bacterial Polysaccharides. The editors have built Bacterial Antigens—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bacterial Polysaccharides in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bacterial Antigens—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Across the Bridge written by Henry Gee and published by University of Chicago Press. This book was released on 2018-07-04 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Addresses an important topic for biologists and zoologists about vertebrates’ place in the ‘grand scheme’ . . . genuinely witty and charming . . . magnificent.” —Neil J. Gostling, University of Southampton Our understanding of vertebrate origins and the backbone of human history evolves with each new fossil find and DNA map. Many species have now had their genomes sequenced, and molecular techniques allow genetic inspection of even non-model organisms. But as longtime Nature editor Henry Gee argues in Across the Bridge, despite these giant strides and our deepening understanding of how vertebrates fit into the tree of life, the morphological chasm between vertebrates and invertebrates remains vast and enigmatic. As Gee shows, even as scientific advances have falsified a variety of theories linking these groups, the extant relatives of vertebrates are too few for effective genetic analysis. Moreover, the more we learn about the species that do remain—from sea-squirts to starfish—the clearer it becomes that they are too far evolved along their own courses to be of much use in reconstructing what the latest invertebrate ancestors of vertebrates looked like. Fossils present yet further problems of interpretation. Tracing both the fast-changing science that has helped illuminate the intricacies of vertebrate evolution as well as the limits of that science, Across the Bridge helps us to see how far the field has come in crossing the invertebrate-to-vertebrate divide—and how far we still have to go. “A beautiful ode to some of the least appreciated animals . . . guides the reader joyfully through deuterostomes—weaving disparate elements of embryology, paleontology, and morphology into an unprecedented and accessible narrative.” —Jakob Vinther, University of Bristol
Book Synopsis Advanced Pharmacology for Prescribers by : Brent Q. Luu, PharmD, BCPS, BCACP
Download or read book Advanced Pharmacology for Prescribers written by Brent Q. Luu, PharmD, BCPS, BCACP and published by Springer Publishing Company. This book was released on 2021-01-13 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivers the critical information primary care providers need to be thoroughly informed prescribers This unique resource—an evidence-based pharmacology text and reference for advanced practice students and clinicians—guides users in analyzing the pharmacological foundations of drug therapy and fosters the development of sound clinical judgment in determining the appropriate medication for every patient across the lifespan. Targeting the specific needs of APRN and PA students and clinicians, the text is a “bridge” between standard, lengthy pharmacology texts and quick pocket references that lack information regarding key pharmacotherapy principles. Featuring an applied therapeutic approach to major disorders and their pharmacologic treatment, the book examines how medications act on the body and visa versa, while teaching the rationale for using specific therapeutic agents or drug classes. Each chapter includes case studies that apply the concepts discussed, relevant diagnostic studies, applicable guidelines, genomics, and important lifespan considerations. Of special interest is a chapter on pharmacogenetics explaining the basic principles underlying our current understanding of genetic variations in response to pharmacotherapy and adverse drug reactions. Easily digestible chapters include objectives and review questions. Ancillary resources include an instructor manual with learning objectives, chapter summaries, and case studies; chapter PowerPoint slides; test bank; and image bank. Key Features: Delivers an applied, evidence-based foundation on the basic science underlying prescribing Targets the specific needs of APRN and PA students and professionals and related healthcare providers Provides clinical decision-making tools and principles to support sound prescribing judgment Focuses on synthesizing drugs to manage commonly occurring disorders Includes strategies for addressing the needs of specific populations throughout the lifespan Includes abundant case studies illuminating key concepts Includes a robust instructor manual with learning objectives, chapter summaries, and case studies; PowerPoint slides; test bank; and image bank. Purchase includes access to the eBook for use on most mobile devices or computers.
Book Synopsis Origin and Evolution of the Vertebrate Immune System by : L. Du Pasquier
Download or read book Origin and Evolution of the Vertebrate Immune System written by L. Du Pasquier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.
