Aluminium and Alzheimer's Disease

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Author :
Publisher : Elsevier
ISBN 13 : 0080525504
Total Pages : 453 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Aluminium and Alzheimer's Disease by : C. Exley

Download or read book Aluminium and Alzheimer's Disease written by C. Exley and published by Elsevier. This book was released on 2001-07-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to impact upon mammalian physiology and function and range from clinical studies, through animal models of disease to the detailed biochemistry of aluminium toxicity. Chapters are also included on epidemiology and other factors involved in the aetiology of Alzheimer's.This is the first time that this subject has been treated in such a comprehensive manner. The research detailed in each chapter, includes the latest research in the field, it has been critically appraised and this appraisal has been used by each author to present an informed opinion of its relevance to aluminium and Alzheimer's disease. The chapters are much more than reviews; they are a statement of the state of the art and of what the future may hold for research in this field. As a whole they show the high quality of research that has been carried out in our efforts to understand the toxicity of aluminium in man and that we are far away from discounting the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease.

Aluminum, Drinking Water, and Alzheimer's Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Aluminum, Drinking Water, and Alzheimer's Disease by : Steve Harold Reiber

Download or read book Aluminum, Drinking Water, and Alzheimer's Disease written by Steve Harold Reiber and published by . This book was released on 1996 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aluminium in Biology and Medicine

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470514310
Total Pages : 326 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Aluminium in Biology and Medicine by : Derek J. Chadwick

Download or read book Aluminium in Biology and Medicine written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examines the chemistry and biology of aluminum compounds focusing on the evidence for and against aluminum's role in Alzheimer's disease.

Neurotoxicity of Aluminum

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Author :
Publisher : Springer
ISBN 13 : 9811313709
Total Pages : 191 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Neurotoxicity of Aluminum by : Qiao Niu

Download or read book Neurotoxicity of Aluminum written by Qiao Niu and published by Springer. This book was released on 2018-10-12 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.

Magnesium in the Central Nervous System

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Author :
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Aluminum and Health

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Author :
Publisher : CRC Press
ISBN 13 : 9780824780265
Total Pages : 318 pages
Book Rating : 4.7/5 (82 download)

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Book Synopsis Aluminum and Health by : H. J. Gitelman

Download or read book Aluminum and Health written by H. J. Gitelman and published by CRC Press. This book was released on 1988-11-04 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hot topic. Contributors address: guidelines for sampling and analyzing aluminum levels in the body, how acid rain alters aluminum in the typical North American diet, the alleged link between aluminum and Alzheimer's disease, the role of aluminum in the dynamics of bone physiology, occupational exp

Aluminum Neurotoxicity

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Author :
Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Aluminum Neurotoxicity by : Leopold Liss

Download or read book Aluminum Neurotoxicity written by Leopold Liss and published by . This book was released on 1980 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurodegeneration and Alzheimer's Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119356784
Total Pages : 548 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Neurodegeneration and Alzheimer's Disease by : Ralph N. Martins

Download or read book Neurodegeneration and Alzheimer's Disease written by Ralph N. Martins and published by John Wiley & Sons. This book was released on 2019-07-10 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.

Alzheimer's Disease: Cellular and Molecular Aspects of Amyloid beta

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780387232256
Total Pages : 442 pages
Book Rating : 4.2/5 (322 download)

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Book Synopsis Alzheimer's Disease: Cellular and Molecular Aspects of Amyloid beta by : J. Robin Harris

Download or read book Alzheimer's Disease: Cellular and Molecular Aspects of Amyloid beta written by J. Robin Harris and published by Springer Science & Business Media. This book was released on 2004-12-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: To understand Alzheimer's disease (AD) is one of the major thrusts of present-day clinical research, strongly supported by more fimdamental cellular, biochemical, immunological and structural studies. It is these latter that receive attention within this book. This compilation of 20 chapters indicates the diversity of work currently in progress and summarizes the current state of knowledge. Experienced authors who are scientifically active in their fields of study have been selected as contributors to this book, in an attempt to present a reasonably complete survey of the field. Inevitably, some exciting topics for one reason or another have not been included, for which we can only apologize. Standardization of terminology is often a problem in science, not least in the Alzheimer field; editorial effort has been made to achieve standardization between the Chapters, but some minor yet acceptable personal / author variation is still present, i. e. P-amyloid/amyloid-P; Ap42/Apl-42/APi. 42! The book commences with a broad survey of the contribution that the range of available microscopical techniques has made to the study of Alzheimer's amyloid plaques and amyloid fibrillogenesis. This chapter also serves as an Introduction to the book, since several of the topics introduced here are expanded upon in later chapters. Also, it is significant to the presence of this chapter that the initial discovery of brain plaques, by Alois Alzheimer, utilized light microscopy, a technique that continues to be extremely valuable in present-day AD research.

Neurotoxicity of Aluminum

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Author :
Publisher : Springer Nature
ISBN 13 : 9819915929
Total Pages : 324 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Neurotoxicity of Aluminum by : Qiao Niu

Download or read book Neurotoxicity of Aluminum written by Qiao Niu and published by Springer Nature. This book was released on 2023-07-08 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.

Reducing the Risk of Alzheimer's

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Author :
Publisher : Stein & Day Pub
ISBN 13 : 9780812831375
Total Pages : 194 pages
Book Rating : 4.8/5 (313 download)

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Book Synopsis Reducing the Risk of Alzheimer's by : Michael A. Weiner

Download or read book Reducing the Risk of Alzheimer's written by Michael A. Weiner and published by Stein & Day Pub. This book was released on 1987 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: A book primarily for healthy people who want to ... avoid getting Alzheimer's disease.

Aluminum and Health

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Publisher :
ISBN 13 :
Total Pages : 9 pages
Book Rating : 4.:/5 (414 download)

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Book Synopsis Aluminum and Health by : Seymour G. Epstein

Download or read book Aluminum and Health written by Seymour G. Epstein and published by . This book was released on 1987 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroprotective Effects of Phytochemicals in Neurological Disorders

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Publisher : John Wiley & Sons
ISBN 13 : 1119155142
Total Pages : 662 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Neuroprotective Effects of Phytochemicals in Neurological Disorders by : Tahira Farooqui

Download or read book Neuroprotective Effects of Phytochemicals in Neurological Disorders written by Tahira Farooqui and published by John Wiley & Sons. This book was released on 2017-03-20 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.

Brain Banking

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Publisher : Elsevier
ISBN 13 : 0444636420
Total Pages : 448 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Brain Banking by :

Download or read book Brain Banking written by and published by Elsevier. This book was released on 2018-02-27 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases. Offers comprehensive coverage of the functional realities of brain banking, with a focus on brain donor recruitment strategies, brain bank networks, ethical issues, and more Serves as a valuable resource for staff in existing brain banks by highlighting best practices Enhances the sharing of expertise between existing banks and highlights a range of techniques applicable to banked tissue for neuroscience researchers Authored by leaders from brain banks around the globe – the broadest, most expert coverage available

Aluminium and Alzheimer's Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (897 download)

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Book Synopsis Aluminium and Alzheimer's Disease by : W. F. Forbes

Download or read book Aluminium and Alzheimer's Disease written by W. F. Forbes and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Issues In Aluminium Toxicity

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Author :
Publisher : CRC Press
ISBN 13 : 9781439805671
Total Pages : 272 pages
Book Rating : 4.8/5 (56 download)

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Book Synopsis Research Issues In Aluminium Toxicity by : A RobertYokel

Download or read book Research Issues In Aluminium Toxicity written by A RobertYokel and published by CRC Press. This book was released on 1997-04-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work focuses primarily on identifying the research needs in this area of neurotoxicology. Based on papers presented for the International Symposium on Aluminium Toxicity, held in Vancouver in 1995, it reviews the knowledge and research required in each specific area.

Relevant Information on Alzheimer's Disease and Aluminum

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (631 download)

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Book Synopsis Relevant Information on Alzheimer's Disease and Aluminum by : Seymour G. Epstein

Download or read book Relevant Information on Alzheimer's Disease and Aluminum written by Seymour G. Epstein and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: