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Advances In Lipobiology
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Book Synopsis Advances in Lipobiology, Volume 1 by : R.W. Gross
Download or read book Advances in Lipobiology, Volume 1 written by R.W. Gross and published by Elsevier. This book was released on 1996-09-24 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipobiology is an interdisciplinary field which incorporates critical aspects of lipid and lipoprotein chemistry into the disciplines of cell biology and physiology. During the last decade, advances in our understanding of the structure and function of lipids, biological membranes and lipid-derived second messengers have underscored the importance of lipids in the regulation of cellular function. This series focuses on salient aspects of the role of lipids in metabolic regulation and cellular activation, with emphasis on emerging concepts and technologies. One goal of this series is to formulate cohesive criteria upon which a foundation for the evaluation of recent work can be based and future directions of research identified.
Download or read book Advances in Lipobiology written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Lipobiology, Volume 2 by : R.W. Gross
Download or read book Advances in Lipobiology, Volume 2 written by R.W. Gross and published by Elsevier. This book was released on 1997-10-21 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Lipobiology, Volume 2
Book Synopsis Advances in Lipobiology by : R.W. Gross
Download or read book Advances in Lipobiology written by R.W. Gross and published by Elsevier Science. This book was released on 1997-11-04 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Lipobiology, Volume 2 by : R.W. Gross
Download or read book Advances in Lipobiology, Volume 2 written by R.W. Gross and published by Elsevier Science. This book was released on 1997-10-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Structural Biology by : S.K. Malhotra
Download or read book Advances in Structural Biology written by S.K. Malhotra and published by Elsevier. This book was released on 1998-08-02 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 5 in the series Advances in Structural Biology is based upon a selection of articles presented at the Workshop on Molecular Bio-physics of the Cytoskeleton: Microtubule Formation, Structure, Function, and Interactions (August 18-22 1997 at the Banff Conference Centre in Banff, Alberta, Canada). Its main objective was to review the state-of-the-art of the field and stimulate a multidisciplinary investigation into the molecular biology of the cytoskeleton, which is amply manifested in the articles selected and published in this volume.
Book Synopsis Advances in Hemodynamics and Hemorheology, Volume 1 by : T.V. How
Download or read book Advances in Hemodynamics and Hemorheology, Volume 1 written by T.V. How and published by Elsevier. This book was released on 1996-09-24 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series presents reviews covering all aspects of haemodynamics and haemorheology. Topics covered include the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood flow in arteries and veins. The contributions aim to reflect the advances being made in experimental techniques and instrumentation for laboratory and clinical measurements and in numerical and mathematical modelling. Emphasis is placed on the scientific and engineering principles involved, but particular attention is also given to the clinical significance of this area of research. Topics covered by this volume include viscoelastic properties of blood and blood analogues; blood flow through narrow tubes; and numerical modelling of blood flow.
Book Synopsis Advances in Amino Acid Mimetics and Peptidomimetics by : A. Abell
Download or read book Advances in Amino Acid Mimetics and Peptidomimetics written by A. Abell and published by Elsevier. This book was released on 1997-11-19 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptidomimetics are compounds which mimic the biological activity of peptides while offering the advantages of increased bioavailability, biostability, bioefficiency, and bioselectivity against the natural biological target of the parent peptide. Examples of peptidomimetics have been isolated as natural products, synthesized as libraries from novel subunits, and designed on the basis of X-ray crystallographic studies and through an intricate knowledge of the biological mode of action of natural peptides. They offer challenging synthetic targets and are increasingly important medicinal agents and biological probes. As a consequence, peptidomimetics embrace much of what is modern medicinal and organic chemistry. This volume highlights some recent and exciting developments in the area.
Book Synopsis Lipobiology by : G. J. van der Vusse
Download or read book Lipobiology written by G. J. van der Vusse and published by Gulf Professional Publishing. This book was released on 2004 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Receptors of Cell Adhesion and Cellular Recognition by : A.G. Lee
Download or read book Receptors of Cell Adhesion and Cellular Recognition written by A.G. Lee and published by Elsevier. This book was released on 1996-06-25 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 3 of Biomembranes covers receptors of cell adhesion and cellular recognition. Proteins in the plasma membrane of cells are heavily involved in processes of cell adhesion, but such proteins were not actually isolated and characterized until the mid-1970s. Since then, application of the methods of molecular biology has led to the recognition of four major classes of cell adhesion molecule (CAMs), the immunoglobulin super family, the cadherins, the integrins, and the selecting. A convenient system in which to study the importance of cell adhesion is in blood platelets where aggregation eventually leads to thrombus formation in a process involving a range of surface glycoproteins. Interaction with the extracellular matrix is exemplified by CD44, the receptor for hyaluronan, and a complex carbohydrate that is a major component of the extracellular matrix surrounding migrating and proliferating cells. Membrane-associated mucins have a variety of effects on cell adhesion. The super family of immunoglobulin related proteins also include the T cell receptors and the major histocompatibility complex (MHC), which, together with the receptors for immunoglobulins (the Fc receptors), are of fundamental importance in the processes of immunity. Volume 3 of Biomembranes explores the structures and functions of the molecules involved in these important functions of the cell.
Download or read book Cell Adhesion written by D.R. Colman and published by Elsevier. This book was released on 1997-02-24 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: One prerequisite for the evolution of multicellular organisms was the invention of mechanisms by which cells could adhere to one another. At some point in our history, dividing cells no longer went their separate protozoic ways in the primordial oceans, but instead found that by maintaining an association, by sticking together but not fusing, numerous evolutionary advantages became possible. The subsequent development of specialized tissues and organs depended on the elaboration of incredibly sophisticated, regulatable cell-to-cell adhesion mechanisms which are known to operate in biological processes as diverse as the growth of the embryo, the immune response, the establishment of connections between nerve cells, and arteriosclerosis, to name just a few. Although we can only guess at the ancestral mechanisms that fostered the first primitive intercellular unions, some one billion years ago, we now recognize contemporary molecular "themes" with presumably ancient origins that mediate cell-cell interactions. The chapters in this book serve as useful, thought-provoking, but not exhaustive, commentaries on contemporary topics within the broad field of cell adhesion. If the reader detects a slight tilt toward those adhesion molecules that function in the nervous system, this is merely a reflection of this editor's interests, biases, and of course, limitations.
Book Synopsis Cytoskeleton in Specialized Tissues and in Pathological States by : J.E. Hesketh
Download or read book Cytoskeleton in Specialized Tissues and in Pathological States written by J.E. Hesketh and published by Elsevier. This book was released on 1996-06-25 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume deals with aspects of the cytoskeleton in different cell types and also describe examples of changes in the cytoskeleton which occur during various pathological states. These studies bring the exciting area of cytoskeleton research into the domain of medical science.
Book Synopsis Myocardial Preservation and Cellular Adaptation by : D.K. Das
Download or read book Myocardial Preservation and Cellular Adaptation written by D.K. Das and published by Elsevier. This book was released on 1998-12-18 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living organisms exhibit specific responses when confronted with sudden changes in their environmental conditions. The ability of the cells to acclimate to their new environment is the integral driving force for adaptive modification of the cells. Such adaptation involves a number of cellular and biochemical alteration including metabolic homeostasis and reprogramming of gene expression. Changes in metabolic pathways are generally short-lived and reversible, while the consequences of gene expression are a long-term process and may lead to permanent alternation in the pattern of adaptive responses. The heart possesses remarkable ability to adapt itself against any stressful situation by increasing resistance to the adverse consequences. Stress composes the foundation of many degenerative heart diseases including atherosclerosis, spasm, thrombosis, cardiomyopathy, and congestive heart failure. Based on the concept that excessive stress may play a crucial role in the pathogenesis of ischemic heart disease, attempts were made to design methods for preventing of myocardial injury. Creation of stress reactions by repeated ischemia and reperfusion or subjecting the hearts to heat or oxidative stress enables them to meet the future stress challenge. Repeated stress exposures adapt the heart to withstand more severe stress reactions probably by upregulating the cellular defense and direct accumulation of intracellular mediators, which presumably constitute the material basis of increased adaptation to stress. Thus, the powerful cardioprotective effect of adaptation is likely to originate at the cellular and molecular levels that compose fundamental processes in the prophylaxis of such diseases. Volume six of the Advances in Organ Biology series contains state-of-the-art reviews on myocardial preservation and cellular adaptation from the leading authorities in this subject.
Book Synopsis Diacylglycerol Kinase Signalling by : Isabel Merida
Download or read book Diacylglycerol Kinase Signalling written by Isabel Merida and published by Frontiers Media SA. This book was released on 2017-11-23 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DG), catalyzing its conversion into phosphatidic acid (PA). This reaction attenuates membrane DG levels, limiting the localization/activation of signaling proteins that bind this lipid. Initially recognized as modulators of classical and novel PKC family members, the function of the DGK has further expanded with the identification of novel DG effectors including Ras Guanyl nucleotide-releasing proteins (RasGRP) and chimaerin Rac GTPases. The product of the DGK reaction, PA, is also a signaling lipid that mediates activation of multiple proteins including the mammalian target of rapamycin (mTOR). The DGK pathway thus modulates two lipids with important signaling properties that are also key intermediates in lipid metabolism and membrane trafficking. The DGK family in eukaryotes comprises 10 different members grouped into five different subfamilies characterized by the presence of particular regulatory motifs. These regions allow the different DGK isoforms to establish specific complexes and/or to be recruited to specific subcellular compartments. The subtle regulation of DG and PA catalyzed byspecific DGKs is sensed by a restricted set of molecules, providing the means for spatio-temporal regulation of signals in highly specialized cell systems. In the recent years, multiple studies have unveiled the functions of specific isoforms, their mechanisms of regulation and their participation in different pathways leading to and from DG and PA. Animal models have greatly helped to understand the specialized contribution of DGK mediated signals, particularly in the immune and central nervous systems. Mice deficient for individual DGK isoforms show defects in T and B cell functions, dendritic spine maintenance, osteoclast and mechanical-induced skeletal muscle formation. Studies in flies and worms link DGK mediated DAG metabolism with mTOR- mediated regulation of lifespan and stress responses. In plants DGK mediated PA formation contributes to plant responses to environmental signals. Aberrant DGK function has been recently associated with pathological states, an expected consequence of the essential role of these enzymes in the regulation of multiple tissue and systemic functions. DGK mutations/deletions have been related to human diseases including diabetes, atypical hemolytic-uremic syndrome, Parkinson disease and bipolar disorders. On the contrary DGK upregulation emerges as a non-oncogenic addition of certain tumors and represents one of the main mechanism by which cancer evades the immune attack. As a result, the DGK field emerges an exciting new area of research with important therapeutic potential.
Book Synopsis Bio-inspired Polymers by : Nico Bruns
Download or read book Bio-inspired Polymers written by Nico Bruns and published by Royal Society of Chemistry. This book was released on 2016-10-14 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many key aspects of life are based on naturally occurring polymers, such as polysaccharides, proteins and DNA. Unsurprisingly, their molecular functionalities, macromolecular structures and material properties are providing inspiration for designing new polymeric materials with specific functions, for example, responsive, adaptive and self-healing materials. Bio-inspired Polymers covers all aspects of the subject, ranging from the synthesis of novel polymers, to structure-property relationships, materials with advanced properties and applications of bio-inspired polymers in such diverse fields as drug delivery, tissue engineering, optical materials and lightweight structural materials. Written and edited by leading experts on the topic, the book provides a comprehensive review and essential graduate level text on bio-inspired polymers for biochemists, materials scientists and chemists working in both industry and academia.
Book Synopsis Lipid Second Messengers by : Ronald P. Rubin
Download or read book Lipid Second Messengers written by Ronald P. Rubin and published by CRC Press. This book was released on 2020-10-14 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipid Second Messengers provides detailed methodology for analysis of various lipid signaling pathways. Authoritative contributors explain the factors that regulate lipid second messenger production by agonist-activated enzymes and examine their products. Topics discussed include procedures used to measure lipid-derived mediators such as lysophospholipids, arachidonic acid, eicosanoids, anandamide, and ceramides, and the enzymes responsible for generating these messengers, such as phospholipases, prostaglandin endoperoxide synthases, and sphingomyelinase.
Book Synopsis Lipid-Mediated Signaling by : Eric J. Murphy
Download or read book Lipid-Mediated Signaling written by Eric J. Murphy and published by CRC Press. This book was released on 2010-03-05 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade's worth of advances in research techniques that are pertinent in understand
