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Advances In Head And Neck Cancer Immunology And Immunotherapy
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Book Synopsis Advances in Head and Neck Cancer Immunology and Immunotherapy by : Rasha Abu-Eid
Download or read book Advances in Head and Neck Cancer Immunology and Immunotherapy written by Rasha Abu-Eid and published by Frontiers Media SA. This book was released on 2019-06-19 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the immunology of different cancers has led to great advances in developing cancer immunotherapies which are successfully used in generating effective anti-tumour immune responses. Head and neck cancers are no exception and various immunotherapies are now under study for the treatment of this diverse group of diseases. The articles in in this eBook provide a range of topics that highlight some of the latest advances in head and neck cancer immunology and immunotherapy. The authors of these articles provide their unique insight and expertise and suggest future directions for translational clinical research.
Book Synopsis Immune Checkpoint Inhibitors in Cancer by : Fumito Ito
Download or read book Immune Checkpoint Inhibitors in Cancer written by Fumito Ito and published by Elsevier Health Sciences. This book was released on 2018-09-03 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It's an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. - Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. - Helps you translate current research and literature into practical information for daily practice. - Presents information logically organized by disease site. - Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. - Consolidates today's available information on this timely topic into one convenient resource.
Book Synopsis Cancer Immunotherapy Principles and Practice by : Lisa H. Butterfield
Download or read book Cancer Immunotherapy Principles and Practice written by Lisa H. Butterfield and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part 1: Intratumoral Signatures Associated With Immune Responsiveness
Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Book Synopsis Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy by : Maria E. Suarez-Almazor
Download or read book Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy written by Maria E. Suarez-Almazor and published by Springer Nature. This book was released on 2021-02-16 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease. This handbook provides clinicians with a comprehensive overview of the management of rheumatic irAE that develop from cancer immunotherapy. It focuses on the irAE seen with ICI, the most frequently used agents in treating cancer. It provides an overview of cancer immunology, immunotoxicity, and immunotherapies such as ICI, cytokine-based therapy, and CART. It examines the epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of a variety of rheumatic immune-related adverse events arising from these therapies. Chapters also cover cancer immunotherapy in patients with preexisting rheumatic diseases such as inflammatory arthritis and other connective tissue disorders. The book helps clinicians to distinguish the current types of cancer immunotherapy and general toxicity patterns, recognize and diagnose rheumatic clinical syndromes, understand the pathogenesis of irAE, and consider risk–benefit ratios when managing patients with rheumatic irAE. Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses alike in rheumatology, clinical immunology, oncology, and internal medicine.
Book Synopsis Tumor Immunology and Immunotherapy by : Robert C. Rees
Download or read book Tumor Immunology and Immunotherapy written by Robert C. Rees and published by Oxford University Press, USA. This book was released on 2014 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Book Synopsis Tertiary Lymphoid Structures by : Marie-Caroline Dieu-Nosjean
Download or read book Tertiary Lymphoid Structures written by Marie-Caroline Dieu-Nosjean and published by Humana Press. This book was released on 2018-09-05 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
Book Synopsis Cancer Immunology and Immunotherapy by : Glenn Dranoff
Download or read book Cancer Immunology and Immunotherapy written by Glenn Dranoff and published by Springer Science & Business Media. This book was released on 2011-04-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz
Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.
Book Synopsis Reconstruction of the Head and Neck by : Eric M. Genden
Download or read book Reconstruction of the Head and Neck written by Eric M. Genden and published by Thieme. This book was released on 2012-05-25 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thieme congratulates Eric M. Genden on being chosen by New York magazine for its prestigious ‘Best Doctors 2017' list. A unique approach to surgical reconstruction of the head and neck" Written and edited by renowned leaders in the field, Reconstruction of the Head and Neck takes a defect-oriented approach that enables surgeons to match their patients' defects with those included in the book and offers clinicians excellent guidance on the latest techniques for achieving optimal functional and aesthetic surgical results. Topics covered include oromandibular complex reconstruction, skull base reconstruction, microvascular reconstruction, and more. Special Features: Authors have organized the chapters by specific defect, so readers can easily find the reconstructive options for their patients Experts cover the reconstruction of major soft tissue, bony and muscular defects of the head, neck, and skull base in detail More than 200 color illustrations help clarify the surgical methods described in the text Experienced surgeons review approaches to reconstruction and the fine points that surgeons need to know for the best outcomes For each defect, the steps in the procedure, the orientations of the flap, and the details that confer excellent surgical results are covered. Surgeons and fellows involved in head and neck reconstruction will greatly benefit from the extensive coverage of the best methods to treat some of the most challenging defects they will face.
Book Synopsis Treatment of Bone and Soft Tissue Sarcomas by : Per-Ulf Tunn
Download or read book Treatment of Bone and Soft Tissue Sarcomas written by Per-Ulf Tunn and published by Springer Science & Business Media. This book was released on 2008-12-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.
Book Synopsis Improving Outcomes in Oral Cancer by : Deepak Kademani
Download or read book Improving Outcomes in Oral Cancer written by Deepak Kademani and published by Springer Nature. This book was released on 2019-11-13 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together experts in the field of maxillofacial and head and neck oncology to provide a comprehensive clinical and translational update on oral cancer that focuses especially on prognosis. Readers will find up-to-date information on disease staging and the pathological, genetic, and surgical factors that affect patient outcomes. Individual chapters describe the most recent advances in radiotherapy, chemotherapy, and immunotherapy, again with careful analysis of the treatment-related factors relevant to response and survival. Management of premalignant lesions and risk factors for malignant transformation are discussed, and the latest knowledge on chemoprevention is presented. Further topics to be addressed include reconstruction of oral cancer defects, salvage options in the event of recurrence, and the prediction of quality of life following treatment. The book will be of value to all clinicians who care for patients with oral cancer in their everyday practice.
Book Synopsis Translational Research in Breast Cancer by : Dong-Young Noh
Download or read book Translational Research in Breast Cancer written by Dong-Young Noh and published by Springer Nature. This book was released on 2021-05-13 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
Book Synopsis HPV Infection in Head and Neck Cancer by : Wojciech Golusiński
Download or read book HPV Infection in Head and Neck Cancer written by Wojciech Golusiński and published by Springer. This book was released on 2016-10-03 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is exceptional in presenting an interdisciplinary approach to the subject of human papillomavirus (HPV) infection in the context of head and neck cancer. Leading experts in the field discuss the epidemiology and molecular biology of HPV-positive head and neck squamous cell carcinoma, HPV testing, the nonsurgical and surgical treatment of HPV-positive tumors, predictive factors for outcome and quality of life, and ongoing trials on the effectiveness of vaccination in disease prevention. It also provides recommendations for testing, diagnosis treatment and vaccination. Otolaryngologists, head and neck surgeons, medical oncologists, radiation oncologists, molecular biologists and pathologists will find this book a valuable resource.
Book Synopsis The Basics of Cancer Immunotherapy by : Haidong Dong
Download or read book The Basics of Cancer Immunotherapy written by Haidong Dong and published by Springer. This book was released on 2018-01-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease. Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems. Some key features of the book are: Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy. Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy. Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.
Book Synopsis Head and Neck Cancer by : Jacques Bernier
Download or read book Head and Neck Cancer written by Jacques Bernier and published by Springer. This book was released on 2016-08-22 with total page 877 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks. In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
Book Synopsis Advances in Cancer Immunotherapy by : Tasuku Honjo
Download or read book Advances in Cancer Immunotherapy written by Tasuku Honjo and published by . This book was released on 2021 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
