Advanced Techniques in Diagnostic Microbiology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387328920
Total Pages : 550 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Advanced Techniques in Diagnostic Microbiology by : Yi-Wei Tang

Download or read book Advanced Techniques in Diagnostic Microbiology written by Yi-Wei Tang and published by Springer Science & Business Media. This book was released on 2007-01-16 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical microbiologists are engaged in the field of diagnostic microbiology to determine whether pathogenic microorganisms are present in clinical specimens collected from patients with suspected infections. If microorganisms are found, these are identified and susceptibility profiles, when indicated, are determined. During the past two decades, technical advances in the field of diagnostic microbiology have made constant and enormous progress in various areas, including bacteriology, mycology, mycobacteriology, parasitology, and virology. The diagnostic capabilities of modern clinical microbiology laboratories have improved rapidly and have expanded greatly due to a technological revolution in molecular aspects of microbiology and immunology. In particular, rapid techniques for nucleic acid amplification and characterization combined with automation and user-friendly software have significantly broadened the diagnostic arsenal for the clinical microbiologist. The conventional diagnostic model for clinical microbiology has been labor-intensive and frequently required days to weeks before test results were available. Moreover, due to the complexity and length of such testing, this service was usually directed at the hospitalized patient population. The physical structure of laboratories, staffing patterns, workflow, and turnaround time all have been influenced profoundly by these technical advances. Such changes will undoubtedly continue and lead the field of diagnostic microbiology inevitably to a truly modern discipline. Advanced Techniques in Diagnostic Microbiology provides a comprehensive and up-to-date description of advanced methods that have evolved for the diagnosis of infectious diseases in the routine clinical microbiology laboratory. The book is divided into two sections. The first techniques section covers the principles and characteristics of techniques ranging from rapid antigen testing, to advanced antibody detection, to in vitro nucleic acid amplification techniques, and to nucleic acid microarray and mass spectrometry. Sufficient space is assigned to cover different nucleic acid amplification formats that are currently being used widely in the diagnostic microbiology field. Within each technique, examples are given regarding its application in the diagnostic field. Commercial product information, if available, is introduced with commentary in each chapter. If several test formats are available for a technique, objective comparisons are given to illustrate the contrasts of their advantages and disadvantages. The second applications section provides practical examples of application of these advanced techniques in several "hot" spots in the diagnostic field. A diverse team of authors presents authoritative and comprehensive information on sequence-based bacterial identification, blood and blood product screening, molecular diagnosis of sexually transmitted diseases, advances in mycobacterial diagnosis, novel and rapid emerging microorganism detection and genotyping, and future directions in the diagnostic microbiology field. We hope our readers like this technique-based approach and your feedback is highly appreciated. We want to thank the authors who devoted their time and efforts to produce their chapters. We also thank the staff at Springer Press, especially Melissa Ramondetta, who initiated the whole project. Finally, we greatly appreciate the constant encouragement of our family members through this long effort. Without their unwavering faith and full support, we would never have had the courage to commence this project.

Advanced Techniques in Diagnostic Microbiology

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Author :
Publisher : Springer
ISBN 13 : 3319951114
Total Pages : 760 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Advanced Techniques in Diagnostic Microbiology by : Yi-Wei Tang

Download or read book Advanced Techniques in Diagnostic Microbiology written by Yi-Wei Tang and published by Springer. This book was released on 2018-11-09 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.

Advanced Techniques in Diagnostic Cellular Pathology

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Publisher : John Wiley & Sons
ISBN 13 : 9780470745021
Total Pages : 214 pages
Book Rating : 4.7/5 (45 download)

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Book Synopsis Advanced Techniques in Diagnostic Cellular Pathology by : Mary Hannon-Fletcher

Download or read book Advanced Techniques in Diagnostic Cellular Pathology written by Mary Hannon-Fletcher and published by John Wiley & Sons. This book was released on 2009-03-12 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years cellular pathology has become more closely involved in the direct management of patients with the introduction of molecular technologies and targeted therapies. Advanced Techniques in Diagnostic Cellular Pathology introduces students and professionals to these concepts and the key technologies that are influencing clinical practice today. Each chapter is carefully structured to introduce the very latest techniques and describe their clinical purpose, principle, method and application in cellular pathology. The advantages of various methods for preparing, observing and demonstrating cells and tissues employed to assist in diagnosis are explored, in addition to the use of quantitative methods in the detection and diagnosis of disease. Supplementary web-based material including annotated virtual microscope slides is available with the book. This is provided courtesy of i-Path Diagnostics Ltd and can be accessed online from their website www.pathxl.com Describes the very latest, emerging and established molecular aspects of diagnostic pathology. A clear, focused approach with each chapter containing a summary, a review of basic principles and clinical applications. Includes web-based annotated virtual microscope slides. Contributions from experienced practitioners contain numerous real-world examples illustrating the use of different diagnostic techniques, and their clinical relevance Written by a team of experienced practitioners this book will prove invaluable both to postgraduate biomedical science students who are training to be cellular pathologists and to professionals working in diagnostic and research laboratories as part of their continuing professional development.

Improving Diagnosis in Health Care

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Publisher : National Academies Press
ISBN 13 : 0309377722
Total Pages : 473 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Improving Diagnosis in Health Care by : National Academies of Sciences, Engineering, and Medicine

Download or read book Improving Diagnosis in Health Care written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-12-29 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

Advanced Techniques in Diagnostic Microbiology

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Author :
Publisher : Springer
ISBN 13 : 3319339001
Total Pages : 544 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Advanced Techniques in Diagnostic Microbiology by : Yi-Wei Tang

Download or read book Advanced Techniques in Diagnostic Microbiology written by Yi-Wei Tang and published by Springer. This book was released on 2018-11-09 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.

Home Performance Diagnostics: the Guide to Advanced Testing

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Publisher : the Building Performance Workshop
ISBN 13 : 0615594751
Total Pages : 218 pages
Book Rating : 4.6/5 (155 download)

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Book Synopsis Home Performance Diagnostics: the Guide to Advanced Testing by : Corbett Lunsford

Download or read book Home Performance Diagnostics: the Guide to Advanced Testing written by Corbett Lunsford and published by the Building Performance Workshop. This book was released on 2012-02-28 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: NOW AT YOUR FINGERTIPS: Every performance test for completing a home energy audit. If you're a professional in today's fast-evolving industry of high performance construction and retrofits, then you've probably found yourself wondering a few things: Who can show me how to run that test? How do I get the most out of the equipment I own? Why do the tests work, and how do I explain them? What quality control methods should I use? Which tools will make my job faster and easier? With this guide, experienced and new diagnosticians alike will get step-by-step details on advanced testing, complete with best practices, important concepts and pitfalls, ways to present data to the client, Step-By-Step photographs, and time-saving tips, plus quiz questions for each diagnostic!

Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications

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Author :
Publisher : IGI Global
ISBN 13 : 1605663158
Total Pages : 598 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications by : Exarchos, Themis P.

Download or read book Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications written by Exarchos, Themis P. and published by IGI Global. This book was released on 2009-04-30 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book includes state-of-the-art methodologies that introduce biomedical imaging in decision support systems and their applications in clinical practice"--Provided by publisher.

Basic and Advanced Laboratory Techniques in Histopathology and Cytology

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Publisher : Springer Nature
ISBN 13 : 9811966168
Total Pages : 350 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Basic and Advanced Laboratory Techniques in Histopathology and Cytology by : Pranab Dey

Download or read book Basic and Advanced Laboratory Techniques in Histopathology and Cytology written by Pranab Dey and published by Springer Nature. This book was released on 2023-01-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this well-received book provides detailed information on the basic and advanced laboratory techniques in histopathology and cytology. It offers clear guidance on the principles and techniques of routine and special laboratory techniques. It also covers advanced laboratory techniques such as immunocytochemistry, flow cytometry, liquid-based cytology, polymerase chain reactions, tissue microarray, molecular technology, etc. The book's second edition covers several important recent topics with many new chapters, such as liquid biopsy, artificial neural network, digital pathology, and next-generation sequencing. Each chapter elucidates basic principle, practical methods, troubleshooting, and clinical applications of the technique. It includes multiple colored line drawings, microphotographs, and tables to illustrate each technique. The book is a helpful guide to the post-graduate students and fellows in pathology, practicing pathologists, as well as laboratory technicians, and research students.

Statistical Methods in Diagnostic Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 1118626044
Total Pages : 597 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Statistical Methods in Diagnostic Medicine by : Xiao-Hua Zhou

Download or read book Statistical Methods in Diagnostic Medicine written by Xiao-Hua Zhou and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.

ADVANCED DIAGNOSTIC TECHNIQUES

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Publisher : DENTOMED PUBLICATION HOUSE
ISBN 13 : 9388535626
Total Pages : 84 pages
Book Rating : 4.3/5 (885 download)

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Book Synopsis ADVANCED DIAGNOSTIC TECHNIQUES by : Dr. KANWARDEEP KAUR

Download or read book ADVANCED DIAGNOSTIC TECHNIQUES written by Dr. KANWARDEEP KAUR and published by DENTOMED PUBLICATION HOUSE. This book was released on 2021-08-01 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: The practice of pathology is currently undergoing significant change, in large part due to advances in the analysis of DNA, RNA, and proteins in tissues. These advances have permitted improved biologic insights into many developmental, inflammatory, metabolic, infectious, and neoplastic diseases. Moreover, molecular analysis has also led to improvements in accuracy of disease diagnosis and classification. It is likely that, in the future, these methods will increasingly enter into the day-to-day diagnosis and management of patients.

Atlas of Diagnostic Cytopathology

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Author :
Publisher : Saunders
ISBN 13 :
Total Pages : 888 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Atlas of Diagnostic Cytopathology by : Barbara F. Atkinson

Download or read book Atlas of Diagnostic Cytopathology written by Barbara F. Atkinson and published by Saunders. This book was released on 2004 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New Edition of the field's standard sourcebook delivers thoroughly revised and up-to-date coverage of aspiration and exfoliative cytology and its impact on the practice of anatomic pathology today. Over 1,700 all-new, full-color illustrations capture the appearance of a complete range of cytopathology specimens, their histologic correlations, and the results of relevant ancillary studies. Each chapter discusses the challenges of that specimen site; describes the diagnostic criteria and differential diagnosis; and explains how the diagnosis is reached.

Diagnostic Techniques in Genetics

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Publisher : John Wiley & Sons
ISBN 13 : 0470870265
Total Pages : 270 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Diagnostic Techniques in Genetics by : Jean-Louis Serre

Download or read book Diagnostic Techniques in Genetics written by Jean-Louis Serre and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments within molecular biology and genetic engineering have led to huge advances and changes within the biological sciences especially within the field of human genetics. Diagnostic Techniques in Genetics offers an important overview of how DNA or RNA technology may be applied to a large set of genetic diagnoses. The first part of the book focuses on DNA/RNA applications and includes many of the latest developments in the field combined with routine procedures of genetic diagnoses, for example cloning and sequencing DNA. The DNA applications presented in the first chapter are then each applied to a specific kind of genetic diagnosis and the text concludes with a chapter devoted to population genetics. First published in French by Dunod in 2002, this book is an excellent reference for students taking courses in molecular biology, medicine and medical genetics. It is also a useful introduction for postgraduate students and researchers in the field who require a general overview of genetic diagnoses.

Advanced Automotive Fault Diagnosis

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Publisher : Routledge
ISBN 13 : 1136430830
Total Pages : 289 pages
Book Rating : 4.1/5 (364 download)

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Book Synopsis Advanced Automotive Fault Diagnosis by : Tom Denton

Download or read book Advanced Automotive Fault Diagnosis written by Tom Denton and published by Routledge. This book was released on 2006-08-14 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostics, or fault finding, is a fundamental part of an automotive technician's work, and as automotive systems become increasingly complex there is a greater need for good diagnostic skills. Advanced Automotive Fault Diagnosis is the only book to treat automotive diagnostics as a science rather than a check-list procedure. Each chapter includes basic principles and examples of a vehicle system followed by the appropriate diagnostic techniques, complete with useful diagrams, flow charts, case studies and self-assessment questions. The book will help new students develop diagnostic skills and help experienced technicians improve even further. This new edition is fully updated to the latest technological developments. Two new chapters have been added – On-board diagnostics and Oscilloscope diagnostics – and the coverage has been matched to the latest curricula of motor vehicle qualifications, including: IMI and C&G Technical Certificates and NVQs; Level 4 diagnostic units; BTEC National and Higher National qualifications from Edexcel; International Motor Vehicle qualifications such as C&G 3905; and ASE certification in the USA.

Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition

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Publisher : Springer Science & Business Media
ISBN 13 : 1461437792
Total Pages : 412 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition by : Reza Shaker

Download or read book Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition written by Reza Shaker and published by Springer Science & Business Media. This book was released on 2012-09-14 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition is the first in class comprehensive multidisciplinary text to encompass the entire field of deglutition. The book is designed to serve as a treasured reference of diagnostics and therapeutics for swallowing clinicians from such diverse backgrounds as gastroenterology, speech language pathology, otolaryngology, rehabilitation medicine, radiology and others. Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition brings together up-to-date information on state-of-the–art diagnostic and therapeutic modalities form disciplines of gastroenterology, speech language pathology, otolaryngology and radiology through contributions of 28 innovators, and master clinicians for the benefit of patients and providers alike. It concisely organizes the wealth of knowledge that exists in each of the contributing disciplines into one comprehensive information platform. Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition provides a one-stop destination for members of all specialties to obtain state-of-the-knowledge information on advanced diagnostic modalities and management. It is an essential reference for all deglutologists.

Advanced Characterization Techniques, Diagnostic Tools and Evaluation Methods in Heritage Science

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Author :
Publisher : Springer
ISBN 13 : 3319753169
Total Pages : 110 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Advanced Characterization Techniques, Diagnostic Tools and Evaluation Methods in Heritage Science by : David M. Bastidas

Download or read book Advanced Characterization Techniques, Diagnostic Tools and Evaluation Methods in Heritage Science written by David M. Bastidas and published by Springer. This book was released on 2018-12-29 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details the application of advanced characterisation techniques and diagnostic tools to heritage science, including the evaluation of heritage assets’ condition, their preservation and restoration. It examines the use of electrochemical techniques in conservation science, with a particular focus on how to solve problems in taking on-site measurements. Specifically, it introduces readers to a new gel polymer (GPE) electrochemical cell developed by the authors for the characterisation of metallic heritage objects. Other techniques used to characterise and monitor reinforced concrete objects in more modern buildings are also covered, including non-destructive electrochemical techniques that allow steel corrosion to be assessed in these structures, and in those that are used to protect and repair such buildings. The usefulness of the NMR-Mouse nuclear magnetic resonance sensor in the assessment and preservation of softer heritage materials, such as wood, parchment, bone, and painted walls, is covered, as well as Infrared reflectography for examining paintings and laser cleaning for restoring them. The book introduces ultra-High Performance Liquid Chromatography (u-HPLC) with a diode-array (DAD) and mass–mass (MS-MS) quadruple time-of-flight spectroscopy (QTOF). This new technique can be applied to the analysis and identification of natural and synthetic organic pigments and its use is demonstrated in several case studies. This book provides a rigorous scientific grounding in the application of state-of-the-art techniques in heritage science and conservation, and offers a practical handbook for practitioners.

Biosensor Based Advanced Cancer Diagnostics

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Publisher : Academic Press
ISBN 13 : 0128236515
Total Pages : 439 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Biosensor Based Advanced Cancer Diagnostics by : Raju Khan

Download or read book Biosensor Based Advanced Cancer Diagnostics written by Raju Khan and published by Academic Press. This book was released on 2021-08-25 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. - Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers - Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications - Offers an insight into how to develop cost-effective diagnostics for early detection of cancer

Microscale Diagnostic Techniques

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Publisher : Springer Science & Business Media
ISBN 13 : 3540264493
Total Pages : 268 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Microscale Diagnostic Techniques by : Kenny Breuer

Download or read book Microscale Diagnostic Techniques written by Kenny Breuer and published by Springer Science & Business Media. This book was released on 2005-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microscale Diagnostic Techniques highlights the most innovative and powerful developments in microscale diagnostics. It provides a resource for scientists and researchers interested in learning about the techniques themselves, including their capabilities and limitations. The fields of Micro- and Nanotechnology have emerged over the past decade as a major focus of modern scientific and engineering research and technology. Driven by advances in microfabrication, the investigation, manipulation and engineering of systems characterized by micrometer and, more recently, nanometer scales have become commonplace throughout all technical disciplines. With these developments, an entirely new collection of experimental techniques has been developed to explore and characterize such systems.