Adrenal bioactivation and toxicity of 3-MeSO [sub] 2-DDE, o,p'-DDD and DMBA investigated in tissue slice culture

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Publisher :
ISBN 13 : 9789155451851
Total Pages : 49 pages
Book Rating : 4.4/5 (518 download)

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Book Synopsis Adrenal bioactivation and toxicity of 3-MeSO [sub] 2-DDE, o,p'-DDD and DMBA investigated in tissue slice culture by : Örjan Lindhe

Download or read book Adrenal bioactivation and toxicity of 3-MeSO [sub] 2-DDE, o,p'-DDD and DMBA investigated in tissue slice culture written by Örjan Lindhe and published by . This book was released on 2001 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: I developed a precision-cut adrenal slice culture procedure to investigate cytochrome P450 (CYP) catalysed irreversible binding and adrenocorticolytic effects in human, rodent, and fish adrenal tissue, ex vivo.

A Textbook of Modern Toxicology

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Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 518 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Textbook of Modern Toxicology by : Ernest Hodgson

Download or read book A Textbook of Modern Toxicology written by Ernest Hodgson and published by McGraw-Hill Medical Publishing. This book was released on 1997 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.

Cytochrome P450

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Publisher : Springer Science & Business Media
ISBN 13 : 0387274472
Total Pages : 702 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Cytochrome P450 by : Paul R. Ortiz de Montellano

Download or read book Cytochrome P450 written by Paul R. Ortiz de Montellano and published by Springer Science & Business Media. This book was released on 2007-02-05 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Detoxication Mechanisms

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Publisher :
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.:/5 (41 download)

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Book Synopsis Detoxication Mechanisms by : Richard Tecwyn Williams

Download or read book Detoxication Mechanisms written by Richard Tecwyn Williams and published by . This book was released on 1949 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Adrenal in Toxicology

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Publisher : CRC Press
ISBN 13 : 0748403302
Total Pages : 331 pages
Book Rating : 4.7/5 (484 download)

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Book Synopsis Adrenal in Toxicology by : Philip W. Harvey

Download or read book Adrenal in Toxicology written by Philip W. Harvey and published by CRC Press. This book was released on 1996-03-28 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adrenal gland is vitally important to health and secretes hormones that control many bodily processes ranging from normal metabolism to the response to stressful circumstances. The corticosteroid hormones are the basis for anti-inflammatory medicines and are very widely prescribed. Changes in the function of the adrenal gland, either naturally through stress or disease, or through the action of drugs and chemicals, can have a major impact on the body.; This text focuses on adrenal toxicity, examining how drugs and chemicals can directly and indirectly affect this gland. Coverage includes: classification of the types of adrenal and endocrine toxicity; the mechanistic and molecular basis of toxicity; reasons why the adrenal is the most common target organ in the endocrine system; drug toxicity specific to patients with adrenal disorders; drug- corticosteroid interactions; adverse drug reactions; and how the adrenal gland is vital in tolerance to toxic insult.

Molecular and Biochemical Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 1119042437
Total Pages : 1040 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Molecular and Biochemical Toxicology by : Robert C. Smart

Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2017-11-06 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Alphaherpesviruses

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Publisher : Caister Academic Press Limited
ISBN 13 : 9781904455769
Total Pages : 0 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Alphaherpesviruses by : Sandra Knowles Weller

Download or read book Alphaherpesviruses written by Sandra Knowles Weller and published by Caister Academic Press Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

Toxicology Handbook

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Publisher : Elsevier Australia
ISBN 13 : 0729539393
Total Pages : 543 pages
Book Rating : 4.7/5 (295 download)

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Book Synopsis Toxicology Handbook by : Lindsay Murray

Download or read book Toxicology Handbook written by Lindsay Murray and published by Elsevier Australia. This book was released on 2011 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Toxicology Handbook 2e is a practical, didactic guide to the approach, assessment and management of poisoned patients. It has been written for hospital-based doctors at all levels and describes the risk assessment-based approach pioneered by the principal authors. the concise layout enables the reader to quickly locate information in a poisoning emergency. the book also features locally relevant information on bites, stings and envenoming. This book will also be useful for ambulance service paramedics and pharmacists.

Introduction to Biochemical Toxicology

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Publisher : Wiley-Interscience
ISBN 13 : 9780471333340
Total Pages : 0 pages
Book Rating : 4.3/5 (333 download)

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Book Synopsis Introduction to Biochemical Toxicology by : Ernest Hodgson

Download or read book Introduction to Biochemical Toxicology written by Ernest Hodgson and published by Wiley-Interscience. This book was released on 2001-02-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Biochemical Toxicology Third Edition Over the past several decades, biochemical toxicology has contributed greatly to the advancement of scientific disciplines ranging from medicine and pharmacology to environmental science and industrial hygiene. In its never-ending quest to define the biochemical, cellular, and molecular events occurring when toxicants interact with organisms, biochemical toxicology provides the rational basis for, among other things, our understanding of acute and chronic toxic processes, the development of new therapies, the determination of toxic hazards, and the development of medical and agricultural biocides. Recent applications of new molecular and cellular techniques have greatly expanded our knowledge of how toxicants produce their adverse effects. As a consequence, the time has come for a substantial revision of Professor Ernest Hodgson's classic reference in the field. This Third Edition now contains updated overview chapters on immunochemical and molecular techniques. It also features entirely new chapters covering such crucial topics as immunotoxicology, cutaneous toxicology, reproductive and developmental toxicology, and molecular epidemiology.

Principles of Biochemical Toxicology, Third Edition

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Publisher : CRC Press
ISBN 13 : 9780748407378
Total Pages : 408 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Principles of Biochemical Toxicology, Third Edition by : John Timbrell

Download or read book Principles of Biochemical Toxicology, Third Edition written by John Timbrell and published by CRC Press. This book was released on 1999-10-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Dictionary of Toxicology

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Publisher : Nature Publishing Group
ISBN 13 : 9781561592166
Total Pages : 504 pages
Book Rating : 4.5/5 (921 download)

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Book Synopsis Dictionary of Toxicology by : Ernest Hodgson

Download or read book Dictionary of Toxicology written by Ernest Hodgson and published by Nature Publishing Group. This book was released on 1998-01-01 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 4,000 insightful definitions, Dictionary of Toxicology is the only book to bring together in one place the language of toxicology. This edition contains 40% new material in areas such as molecular, environmental and regulatory toxicology. In addition, one third of the first edition entries have been revised. A new comprehensive subject area index guides users to all entries pertinent to particular topical areas. Ideal for those studying and/or working in toxicology, pharmacology, medicine, biotechnology, R&D in industry, government and science policy.

Casarett and Doull's Toxicology

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Publisher : McGraw-Hill Professional Publishing
ISBN 13 : 9780070349636
Total Pages : 0 pages
Book Rating : 4.3/5 (496 download)

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Book Synopsis Casarett and Doull's Toxicology by : Louis J. Casarett

Download or read book Casarett and Doull's Toxicology written by Louis J. Casarett and published by McGraw-Hill Professional Publishing. This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This newest addition to the Companion Handbook Series is perfect for the toxicologist or pharmacy student who requires a brief introduction to the fundamental principles of toxicology but does not have immediate access to the textbook, nor the time for consultation. Fully page referenced to the classic text in the field, concepts are organized and presented in a logical progression from general principles to specific topics such as organ system toxicology, specific agent toxicology, and environmental toxicology. Where possible the information is summarized in tables or presented in outline format.

General and Applied Toxicology

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Publisher :
ISBN 13 : 9781561592425
Total Pages : 2199 pages
Book Rating : 4.5/5 (924 download)

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Book Synopsis General and Applied Toxicology by : Bryan Ballantyne

Download or read book General and Applied Toxicology written by Bryan Ballantyne and published by . This book was released on 1999 with total page 2199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Toxicology

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Publisher : Elsevier
ISBN 13 : 0080468845
Total Pages : 6448 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2010-06-01 with total page 6448 pages. Available in PDF, EPUB and Kindle. Book excerpt: An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version

Environmental Toxicants

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Publisher : John Wiley & Sons
ISBN 13 : 0470442883
Total Pages : 1189 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Environmental Toxicants by : Morton Lippmann

Download or read book Environmental Toxicants written by Morton Lippmann and published by John Wiley & Sons. This book was released on 2009-03-26 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the most current information and research available for performing risk assessments on exposed individuals and populations, giving guidance to public health authorities, primary care physicians, and industrial managers Reviews current knowledge on human exposure to selected chemical agents and physical factors in the ambient environment Updates and revises the previous edition, in light of current scientific literature and its significance to public health concerns Includes new chapters on: airline cabin exposures, arsenic, endocrine disruptors, and nanoparticles

Air Pollution Injury to Vegetation

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Publisher :
ISBN 13 :
Total Pages : 52 pages
Book Rating : 4.:/5 (25 download)

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Book Synopsis Air Pollution Injury to Vegetation by : Ibrahim Joseph Hindawi

Download or read book Air Pollution Injury to Vegetation written by Ibrahim Joseph Hindawi and published by . This book was released on 1970 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Toxicology

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Publisher : Elsevier
ISBN 13 : 0080548008
Total Pages : 9894 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Encyclopedia of Toxicology by : Bruce Anderson

Download or read book Encyclopedia of Toxicology written by Bruce Anderson and published by Elsevier. This book was released on 2005-05-31 with total page 9894 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the Encyclopedia of Toxicology continues its comprehensive survey of toxicology. This new edition continues to present entries devoted to key concepts and specific chemicals. There has been an increase in entries devoted to international organizations and well-known toxic-related incidents such as Love Canal and Chernobyl. Along with the traditional scientifically based entries, new articles focus on the societal implications of toxicological knowledge including environmental crimes, chemical and biological warfare in ancient times, and a history of the U.S. environmental movement. With more than 1150 entries, this second edition has been expanded in length, breadth and depth, and provides an extensive overview of the many facets of toxicology. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. *Second edition has been expanded to 4 volumes *Encyclopedic A-Z arrangement of chemicals and all core areas of the science of toxicology *Covers related areas such as organizations, toxic accidents, historical and social issues, and laws *New topics covered include computational toxicology, cancer potency factors, chemical accidents, non-lethal chemical weapons, drugs of abuse, and consumer products and many more!