Diversity of the Microbial World

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Publisher : Frontiers Media SA
ISBN 13 : 2889636658
Total Pages : 86 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Diversity of the Microbial World by : Angélica Cibrián-Jaramillo

Download or read book Diversity of the Microbial World written by Angélica Cibrián-Jaramillo and published by Frontiers Media SA. This book was released on 2020-07-17 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbes, or microorganisms, are tiny living beings that cannot be seen by the naked eye. These little guys are one of the oldest living things on Earth, and are extremely diverse in how they live and what they can do. They, for example, can live in many places, from the freezing iciness of glaciers, to the insides of other organisms, like termites or humans. Since they are virtually everywhere, microorganisms are essential for the biological processes that allow plants and animals to breath, eat and thrive. But how were they able to endure, adapt and flourish constantly over millions of years? The secrets of their success are still within them, coded into their genomes, waiting for us to understand them. Now, genomes, bacterial or otherwise, are the repositories of life. These repositories store almost every bit of information that allows living beings to live in discrete units called genes. Genes are strung together like the sentences in a book, interacting with each other to create meaning, saving the story of that particular book—or that particular living organism’s genome—so it can be copied, modified, corrected or enhanced, and then passed on to new generations. After many, many years of studying these “books,” we have learned to read and understand them, thanks to the technological innovations of the last decade. Nowadays, it is possible to get the full genomic sequence of practically any organism, and compare it with thousands of genomes from other organisms, letting us peek at the secrets that make each organism who it is. With the current technical abilities, the challenge now is not to obtain the information but to interpret all those chunks of the story. Finding ways to untangle the riddles of genomic information is the work of Genomics, the science that allows us to obtain, analyze and prioritize information among the many stories that we sequence everyday. To do this, Genomics draws from many sciences, like mathematics and computing sciences, making it a truly interdisciplinary endeavor. Right now , genomics are one of the most important areas of biology, and many, if not most, of current biological studies use at least a little bit of genomics. For example, genomics can be used to identify a microbe and give it a name, to learn about what types of things it can do or places it can live, and to figure out the mechanisms that enable it to survive under particular conditions. Here, we will dwell on some of the basic questions about microbial adaptation, biodiversity, and their relationships with other living beings using a genomic approach. We will also focus on the environment, trying to understand how such tiny little creatures are capable of solving their daily problems, and how they can alter the places in which they live. Learning about these mechanisms will not only provide us with knowledge about life in general but will also help us to understand these organisms as a fundamental component of our ecosystem, including their harmful and beneficial effects in all aspects of our daily life, which can be translated into useful applications in almost any imaginable way.

Microbial Evolution

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Publisher :
ISBN 13 : 9781621820376
Total Pages : 0 pages
Book Rating : 4.8/5 (23 download)

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Book Synopsis Microbial Evolution by : Howard Ochman

Download or read book Microbial Evolution written by Howard Ochman and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria have been the dominant forms of life on Earth for the past 3.5 billion years. They rapidly evolve, constantly changing their genetic architecture through horizontal DNA transfer and other mechanisms. Consequently, it can be difficult to define individual species and determine how they are related. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines how bacteria and other microbes evolve, focusing on insights from genomics-based studies. Contributors discuss the origins of new microbial populations, the evolutionary and ecological mechanisms that keep species separate once they have diverged, and the challenges of constructing phylogenetic trees that accurately reflect their relationships. They describe the organization of microbial genomes, the various mutations that occur, including the birth of new genes de novo and by duplication, and how natural selection acts on those changes. The role of horizontal gene transfer as a strong driver of microbial evolution is emphasized throughout. The authors also explore the geologic evidence for early microbial evolution and describe the use of microbial evolution experiments to examine phenomena like natural selection. This volume will thus be essential reading for all microbial ecologists, population geneticists, and evolutionary biologists.

Microbial Evolution and Co-Adaptation

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Publisher : National Academies Press
ISBN 13 : 0309131219
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine

Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

What You Need to Know about Infectious Disease

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis What You Need to Know about Infectious Disease by : Madeline Drexler

Download or read book What You Need to Know about Infectious Disease written by Madeline Drexler and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

When Giants Shift

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Publisher : Tredition Gmbh
ISBN 13 : 9783384268983
Total Pages : 0 pages
Book Rating : 4.2/5 (689 download)

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Book Synopsis When Giants Shift by : Sakina

Download or read book When Giants Shift written by Sakina and published by Tredition Gmbh. This book was released on 2024-06-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "When Giants Shift: How Tiny Bacteria Adapt to a Warming World" shrinks us down to the microscopic level to explore the fascinating world of bacteria and their response to a changing climate. Often seen as villains, this book reveals bacteria as resilient and adaptable giants (in their own tiny way) at the forefront of climate change. Discover how these microscopic marvels are shifting their behavior and communities as global temperatures rise. You'll learn how some bacteria thrive in hotter environments, potentially accelerating worrying processes, while others offer unexpected solutions. "When Giants Shift" explores the potential consequences of these bacterial adaptations - will they exacerbate climate change or offer a chance to mitigate its effects? The book delves into cutting-edge research on how scientists are studying these tiny climate influencers and their potential role in the fight for a sustainable future. This captivating look at the microscopic world will leave you with a newfound appreciation for bacteria and their surprising impact on our planet's future.

The Social Biology of Microbial Communities

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Publisher : National Academies Press
ISBN 13 : 0309264324
Total Pages : 633 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Social Biology of Microbial Communities by : Institute of Medicine

Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.

HALOPHILIC BACTERIA

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Publisher : Springer
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis HALOPHILIC BACTERIA by : Francisco Rodriguez-Valera

Download or read book HALOPHILIC BACTERIA written by Francisco Rodriguez-Valera and published by Springer. This book was released on 1988 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Threats to Health

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Publisher : National Academies Press
ISBN 13 : 0309185548
Total Pages : 397 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Threats to Health by : Institute of Medicine

Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Molecular Basis of Specific Mechanism for Bacterial Adaptation

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Publisher :
ISBN 13 : 9781536187519
Total Pages : 0 pages
Book Rating : 4.1/5 (875 download)

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Book Synopsis Molecular Basis of Specific Mechanism for Bacterial Adaptation by : Marcos López Pérez

Download or read book Molecular Basis of Specific Mechanism for Bacterial Adaptation written by Marcos López Pérez and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the appearance of Darwin's book, "The Origin of Species," adaptation is one of the processes that explains the diversity of species in ecosystems. Adaptive phenomena in the 19th century and until the mid-20th century have been analyzed in macroscopic biological systems, however since the second half of the 20th century and to date the development of disciplines such as Molecular Biology, has allowed us to delve into the mechanisms that regulate cell physiology. The molecular bases that allow explaining the adaptation processes of microorganisms to their environment have special relevance, because through their analysis it is possible to size the complexity of these mechanisms that involve receptors of a protein nature associated with transduction chains that transport the information flow to genomic DNA, and which subsequently involves the emission of a response through the expression of specific genes. From the point of view of the adaptive phenomenon analysis, the approach through the molecular bases makes it possible to understand the enormous diversity of the microbial world. Mainly for two reasons, on the one hand the presence of micro gradients in the bacterial ecological niches that are continuously fluctuating, which forces the microorganisms to a rapid adaptation phenomenon. And on the other hand, horizontal gene transfer phenomena, which allow bacteria the information exchange. These two elements carry great intensity in establishing new relationships. This phenomenon is especially relevant if it is related to a concept that Darwin cites in the Origin of Species, "The tangled riverbank", where it is emphasized that the new interactions establishment is the basic driving force for the new species generation. This mechanism is explained by the positive feedback loop generation, whereby ecosystems with high levels of biological diversity generate new interactions that lead to new species, which in turn tends to make the ecosystem network more complex. This complexity analyzed in its molecular bases allows to generate new research questions that can be applied to other knowledge areas, such as Biotechnology. The analysis of the molecular bases of the microorganisms adequacy, makes it possible to identify and characterize mechanisms that implemented in different pharmaceutical areas and agricultural industry has led to the product generation with high added value, a clear example of this economic development is the enzyme industry and even recombinant protein production. Finally, it is convenient to emphasize the need to incorporate the analysis of the molecular bases of adaptation from the perspective of omics techniques. Techniques that allow the study of processes and mechanisms to be approached from a global perspective. This book summarizes some topics of special relevance referring to adaptive processes of different microorganisms of special relevance both in basic and applied research.

Adaptations to a Microbial World

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Publisher :
ISBN 13 :
Total Pages : 322 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Adaptations to a Microbial World by : Angela Michelle Early

Download or read book Adaptations to a Microbial World written by Angela Michelle Early and published by . This book was released on 2014 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organisms are in constant contact with both harmful and benign microbes. Evolutionary approaches can enrich our understanding of these interactions and provide insight into their dynamics through time and across space. Here, I present an evolutionary study of the fruit fly Drosophila melanogaster to investigate the multiple ways microbes and parasites have shaped the evolution of this model host. Chapter 1 explores D. melanogaster's interactions with its gut bacteria. Using 37 inbred fly lines, I found that fly genotypes differ in their amount of gut bacteria. Gut microbiome size correlated with other phenotypes assayed in these lines, suggesting that commensal bacterial load may influence aspects of fly fitness-from nutrient allocation to mating behavior. While the fly only transiently interacts with these gut microbes, it maintains a lifelong relationship with the endosymbiont Wolbachia pipientis. In Chapter 2, I present a phylogenetic analysis of 65 globally distributed Wolbachia and mitochondrial genomes. Wolbachia infections showed strong geographic structuring and no evidence of horizontal transmission or recombination. Demonstrating a tight evolutionary relationship between host and bacteria, I determined that all extant Wolbachia infections in D. melanogaster are monophyletic, coalescing to a single infected individual approximately 2200 years ago. Chapter 3 more broadly considers all classes of parasites, pathogens, and commensals. Leveraging our extensive knowledge of D. melanogaster gene function, I infer global variation in pathogen-induced selection pressures, and find that immune processes differ in extent and route of local adaptation. Parasitoid wasps and viruses have most profoundly impacted the recent evolution of D. melanogaster immune genes, but the underlying genetic architectures of these adaptive events differ. Genes also experience intra-cellular selection pressures. In Chapter 4, I investigate how these intra-organismal forces shape immune gene adaptation by calculating metrics of network position and pleiotropy for each D. melanogaster immune gene. I found that protein-protein interactions constrain a gene's adaptive potential, but that this constraint is most apparent in processes that experience strong directional selection. Taken together, these studies provide a more complete picture of the multi-faceted nature of host-microbe interactions, and establish an expanded framework for future research in Drosophila immunity.

Uncultivated Microorganisms

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Publisher : Springer Science & Business Media
ISBN 13 : 3540854657
Total Pages : 215 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Uncultivated Microorganisms by : Slava S. Epstein

Download or read book Uncultivated Microorganisms written by Slava S. Epstein and published by Springer Science & Business Media. This book was released on 2009-09-01 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1898, an Austrian microbiologist Heinrich Winterberg made a curious observation: the number of microbial cells in his samples did not match the number of colonies formed on nutrient media (Winterberg 1898). About a decade later, J. Amann qu- tified this mismatch, which turned out to be surprisingly large, with non-growing cells outnumbering the cultivable ones almost 150 times (Amann 1911). These papers signify some of the earliest steps towards the discovery of an important phenomenon known today as the Great Plate Count Anomaly (Staley and Konopka 1985). Note how early in the history of microbiology these steps were taken. Detecting the Anomaly almost certainly required the Plate. If so, then the period from 1881 to 1887, the years when Robert Koch and Petri introduced their key inventions (Koch 1881; Petri 1887), sets the earliest boundary for the discovery, which is remarkably close to the 1898 observations by H. Winterberg. Celebrating its 111th anniversary, the Great Plate Count Anomaly today is arguably the oldest unresolved microbiological phenomenon. In the years to follow, the Anomaly was repeatedly confirmed by all microb- logists who cared to compare the cell count in the inoculum to the colony count in the Petri dish (cf., Cholodny 1929; Butkevich 1932; Butkevich and Butkevich 1936). By mid-century, the remarkable difference between the two counts became a universally recognized phenomenon, acknowledged by several classics of the time (Waksman and Hotchkiss 1937; ZoBell 1946; Jannasch and Jones 1959).

The Hologenome Concept: Human, Animal and Plant Microbiota

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3319042416
Total Pages : 187 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis The Hologenome Concept: Human, Animal and Plant Microbiota by : Eugene Rosenberg

Download or read book The Hologenome Concept: Human, Animal and Plant Microbiota written by Eugene Rosenberg and published by Springer Science & Business Media. This book was released on 2014-01-31 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

Microbial Stress Adaptation and Food Safety

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Publisher : CRC Press
ISBN 13 : 1420012827
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Microbial Stress Adaptation and Food Safety by : Ahmed E. Yousef

Download or read book Microbial Stress Adaptation and Food Safety written by Ahmed E. Yousef and published by CRC Press. This book was released on 2002-12-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to address the subject, Microbial Stress Adaptation and Food Safety emphasizes the implications of stress adaptation and its consequences for food safety. It covers the basic science, kinetics, mechanisms, assessment, and control of stress adaptation and its impact on the safety of foods produced by minimal processing or non-thermal technologies. World renowned experts in the field provide detailed accounts of problems associated with stress adaptation and suggest practical solutions for overcoming these problems.

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bugs as Drugs

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Publisher : John Wiley & Sons
ISBN 13 : 1555819702
Total Pages : 514 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Bugs as Drugs by : Robert A. Britton

Download or read book Bugs as Drugs written by Robert A. Britton and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria

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Publisher : John Wiley & Sons
ISBN 13 : 1119004896
Total Pages : 1472 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria by : Frans J. de Bruijn

Download or read book Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria written by Frans J. de Bruijn and published by John Wiley & Sons. This book was released on 2016-07-13 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.

Microbiome Under Changing Climate

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Publisher : Woodhead Publishing
ISBN 13 : 0323906974
Total Pages : 575 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Microbiome Under Changing Climate by : Ajay Kumar

Download or read book Microbiome Under Changing Climate written by Ajay Kumar and published by Woodhead Publishing. This book was released on 2022-01-21 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiome Under Changing Climate: Implications and Solutions presents the latest biotechnological interventions for the judicious use of microbes to ensure optimal agricultural yield. Summarizing aspects of vulnerability, adaptation and amelioration of climate impact, this book provides an important resource for understanding microbes, plants and soil in pursuit of sustainable agriculture and improved food security. It emphasizes the interaction between climate and soil microbes and their potential role in promoting advanced sustainable agricultural solutions, focusing on current research designed to use beneficial microbes such as plant growth promoting microorganisms, fungi, endophytic microbes, and more. Changes in climatic conditions influence all factors of the agricultural ecosystem, including adversely impacting yield both in terms of quantity and nutritional quality. In order to develop resilience against climatic changes, it is increasingly important to understand the effect on the native micro-flora, including the distribution of methanogens and methanotrophs, nutrient content and microbial biomass, among others. - Demonstrates the impact of climate change on secondary metabolites of plants and potential responses - Incorporates insights on microflora of inhabitant soil - Explores mitigation processes and their modulation by sustainable methods - Highlights the role of microbial technologies in agricultural sustainability