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Active Surveillance For Localized Prostate Cancer
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Book Synopsis Active Surveillance for Localized Prostate Cancer by : Laurence Klotz
Download or read book Active Surveillance for Localized Prostate Cancer written by Laurence Klotz and published by Humana Press. This book was released on 2017-09-29 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
Book Synopsis Active Surveillance for Localized Prostate Cancer by : Laurence Klotz
Download or read book Active Surveillance for Localized Prostate Cancer written by Laurence Klotz and published by Springer Science & Business Media. This book was released on 2012-06-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehensive guide to the management of patients on surveillance. The volume covers the many complexities and nuances to this approach including, patient selection, risk assessment, how to overcome 'cancer hysteria' when counseling patients, identifying appropriate triggers for intervention, use of PSA kinetics and MR imaging information, technique and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.
Book Synopsis An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer by :
Download or read book An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :U. S. Department of Health and Human Services Publisher :CreateSpace ISBN 13 :9781484054628 Total Pages :344 pages Book Rating :4.0/5 (546 download)
Book Synopsis An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer by : U. S. Department of Health and Human Services
Download or read book An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer written by U. S. Department of Health and Human Services and published by CreateSpace. This book was released on 2013-04-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2011, more than 240,000 men are projected to be diagnosed with prostate cancer, and 33,000 are projected to die from the disease in the United States. In the United States, most cases of prostate cancer are detected via prostate-specific antigen (PSA) screening. The cancer is usually localized, and most tumors have low histological grades and low Gleason scores. Indeed, more than half of prostate cancers detected by PSA screening are expected to be early-stage, low-risk tumors. Such cancers are an infrequent cause of death, and those affected are more likely to die of unrelated causes. A number of immediate active treatment options are available for localized prostate cancer. Most commonly, radical prostatectomy (RP) or radiation therapy (RT), with or without androgen deprivation therapy (ADT), are offered with curative intent. However, the clinical benefit of immediate therapy with curative intent has not yet been demonstrated for localized prostate cancer in a PSA-screened population. It is likely that a large number of men are receiving active treatment with curative intent without much likelihood of obtaining any clinical benefit due to the slow progression of many prostate tumors. Both surgical and radiation treatments result in significant short- and long-term adverse events, including impotence, urinary dysfunction, and other complications. Thus, determination of the appropriate management strategy for early-stage, low-risk prostate cancer is an important public health concern. Active surveillance (AS) and watchful waiting (WW) are two observational followup strategies that forgo immediate therapy in patients with prostate cancer, with the goal of minimizing the morbidities and costs of immediate active treatment for men who may never develop cancer-related symptoms or who are interested in palliative treatments only. AS is curative in intent, and WW is palliative. AS is appropriate in men with disease believed to be indolent and therefore may not require therapy. Because prediction tools are imperfect, these men are monitored closely and treated with curative intent at signs of progression or patient choice. In this way, the considerable adverse effects of treatment are at best avoided, and at least deferred. This approach is to be distinguished from men for whom treatment is deemed inappropriate because of comorbidity; for these men, WW is generally considered, as it offers the option of palliative therapy upon symptomatic disease progression. AS often entails a multifactorial followup of patients—monitoring of PSA values, digital rectal examinations (DRE), prostate imaging, and periodic prostate biopsies—while WW is commonly a relatively passive strategy—with interventions triggered by symptoms. However, there is a continuum of aggressiveness of followup for both AS and WW, as practiced in the community. The objective of this report is to summarize the existing literature regarding the role of AS in the management of early-stage, low-risk prostate cancer. Both the report and the corresponding NIH State-of-the-Science conference are a part of the NIH Consensus Development Program, the purpose of which is to evaluate the scientific evidence on a particular topic and develop a consensus statement that advances research in that area. Key Questions provided to the EPC for systematic review include: 1. How have the patient population and the natural history of prostate cancer diagnosed in the United States changed in the last 30 years? 2. How are active surveillance and other observational management strategies defined? 3. What factors affect the offer of, acceptance, and adherence to active surveillance? 4. What are the comparative short- and long-term outcomes of active surveillance versus immediate treatment with curative intent for localized prostate cancer? 5. What are the research needs regarding active surveillance (or watchful waiting) in localized prostate cancer?
Book Synopsis The Prostate Cancer Dilemma by : Nelson N. Stone
Download or read book The Prostate Cancer Dilemma written by Nelson N. Stone and published by Springer. This book was released on 2015-10-19 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in early prostate cancer. The book reviews new data about genetic markers, transperineal mapping biopsy and mpMRI, how to apply each of these technologies in patients with elevated PSA, when a prior prostate biopsy performed by the standard TRUS method is negative and in cases where low risk disease is already diagnosed, how to differentiate those men who might harbor more aggressive disease from those who do not. Over 75% of newly diagnosed prostate cancer meets the criteria for low risk disease which has created a dilemma for both patients and clinicians. Active surveillance programs have been initiated and are reviewed. How the new technologies impact surveillance programs is addressed. Clinical stage designation is updated and a new intra-prostatic staging system is discussed. Prostate biopsy techniques utilizing transrectal ultrasound, transperineal mapping, elastography and mpMRI are compared. Finally, utilization of this new technology in the application of focal therapy is reviewed. The Prostate Cancer Dilemma will serve as a very useful resource for physicians and researchers dealing with, and interested in this challenging malignancy. Chapters are written by experts in their fields and include the most up to date scientific and clinical information as well as links to procedural video content.
Book Synopsis Technical Aspects of Focal Therapy in Localized Prostate Cancer by : Eric Barret
Download or read book Technical Aspects of Focal Therapy in Localized Prostate Cancer written by Eric Barret and published by Springer. This book was released on 2015-01-29 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.
Book Synopsis Management of Prostate Cancer by : Michel Bolla
Download or read book Management of Prostate Cancer written by Michel Bolla and published by Springer Science & Business Media. This book was released on 2012-04-24 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an exhaustive review of the current state of the art in the management of prostate cancer, from screening to treatment. A particular feature is the emphasis placed on the value of a multidisciplinary approach. The opening chapters address basic aspects including epidemiology, biology, and chemoprevention. The role of individual and mass screening is carefully appraised, and diagnosis, clinical work-up, and the role of active surveillance are discussed in detail. Subsequent chapters are devoted to each of the therapies that may be employed, including open and robotic laparoscopic radical prostatectomy, the various forms of radiation therapy, high-intensity focused ultrasound, cryotherapy, hormonal therapy, and targeted therapies and vaccination. Up-to-date data from clinical trials are included. The editors are members of the EORTC who have coordinated phase III EORTC trials and have worldwide reputations.
Book Synopsis The Gleason Grading System by : Epstein
Download or read book The Gleason Grading System written by Epstein and published by Lippincott Williams & Wilkins. This book was released on 2013 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gleason system is the most important prognostic marker of prostate cancer that is critical to patient management and drives therapies across all disciplines dealing with prostate cancer. In addition to an extensive number of photographs, this book discusses in detail clinically related issues that are crucial for the urologist, radiotherapist, and oncologists to know, such as predicting upgrading and downgrading from needle biopsy to radical prostatectomy, risk of Gleason grading change over time, significance of tertiary grade patterns, and prognosis and implications related to various Gleason scores and different therapies. Images that were particularly difficult for contributing pathologists sent in for consultation are used in addition to classic examples, as these cases are the most informative in showing the difficulties with Gleason grading.
Book Synopsis Reading MRI of the Prostate by : Ananya Panda
Download or read book Reading MRI of the Prostate written by Ananya Panda and published by Springer Nature. This book was released on 2020-01-01 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise guide to prostate cancer imaging. Beginning with normal MR anatomy, the book details the various components of a typical mpMRI protocol and discusses MR interpretation and reporting under PI-RADS version 2 guidelines. MR appearances of atypical locations of prostate cancer, common tumor mimics, MR-guided biopsy strategies, and the role of active surveillance are also covered. Reading MRI of the Prostate aims to help urologists and radiologists understand the evaluation and interpretation of prostate MRIs.
Book Synopsis Management of Prostate Cancer by : Michel Bolla
Download or read book Management of Prostate Cancer written by Michel Bolla and published by Springer. This book was released on 2017-01-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach. The editors are very excited about the outstanding new or updated contributions from the different expert authors. The opening chapters address basic aspects including epidemiology, pathology, biology, genetics, and chemoprevention. The role of individual and mass screening is carefully appraised, and extensive attention is devoted to diagnosis and clinical work-up by means of recently implemented investigations such as multiparametric MRI and choline PET-CT. The use of active surveillance is examined in detail. Subsequent chapters discuss the different therapies that may be employed: open and minimally invasive, including robot-assisted, radical prostatectomy, the various forms of radiation treatment, high-intensity focused ultrasound, cryotherapy, hormonal manipulations, chemotherapy, targeted therapies, and immunotherapy. Up-to-date results from practice-changing phase III randomized clinical trials are included and special insights are provided into the interpretation of results and the patient’s perspective.
Book Synopsis Multidisciplinary Management of Prostate Cancer by : Vincenzo Gentile
Download or read book Multidisciplinary Management of Prostate Cancer written by Vincenzo Gentile and published by Springer Science & Business Media. This book was released on 2014-04-11 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is the most common neoplasm in men and its management is very complex, in terms of both diagnosis and treatment. In recent years the value of multidisciplinary management within a prostate cancer unit has been increasingly recognized. Such a multidisciplinary approach within a specialized unit involves a variety of specialists, including urologists, oncologists, radiotherapists, radiologists and pathologists. This book describes in detail the advantages of multidisciplinary management of prostate cancer. It opens by explaining the nature of the required multidisciplinary team and the potential benefits of the prostate cancer unit as a structure for the delivery of specialist multidisciplinary care. Epidemiological aspects favoring multidisciplinary management are described and each element of care within the context of the prostate cancer unit is then discussed; also has been described the role of advanced imaging (Multiparametric MRI) in the management of PCa. Early diagnosis, risk classification, treatment decision making, surgery, radiotherapy, medical therapies and health care support are all fully considered. This book will be informative and enlightening for all who are involved in the management of patients with prostate cancer.
Author :Manish I. Patel Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318071528 Total Pages :194 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts: Prostate Cancer by : Manish I. Patel
Download or read book Fast Facts: Prostate Cancer written by Manish I. Patel and published by Karger Medical and Scientific Publishers. This book was released on 2023-12-07 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is the second most common cancer in men worldwide, but it is unusual among solid tumors in that many men die with, rather than of, the disease. This raises challenges in terms of deciding if, when, and how to intervene to control tumor growth and spread in order to extend survival without compromising quality of life. The many developments in the field since the last edition of this book include continuing studies to improve detection and monitoring of the disease, with the evaluation of MRI for screening and prostate-specific membrane antigen (PSMA)-PET/CT for staging. Treatment options have also continued to improve and expand for all stages of the disease with the development of ultrahypofractionated radiotherapy, oral LHRH antagonists, PARP inhibitors and lutetium-177 PSMA-617 radioligand therapy.
Author :Manish I. Patel Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318072397 Total Pages :194 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts: Prostate Cancer by : Manish I. Patel
Download or read book Fast Facts: Prostate Cancer written by Manish I. Patel and published by Karger Medical and Scientific Publishers. This book was released on 2024-02-27 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is the second most common cancer in men worldwide, but it is unusual among solid tumors in that many men die with, rather than of, the disease. This raises challenges in terms of deciding if, when, and how to intervene to control tumor growth and spread in order to extend survival without compromising quality of life. The many developments in the field since the last edition of this book include continuing studies to improve detection and monitoring of the disease, with the evaluation of MRI for screening and prostate-specific membrane antigen (PSMA)-PET/CT for staging. Treatment options have also continued to improve and expand for all stages of the disease with the development of ultrahypofractionated radiotherapy, oral LHRH antagonists, PARP inhibitors and lutetium-177 PSMA-617 radioligand therapy.
Book Synopsis Chemotherapy and Immunotherapy in Urologic Oncology by : Edouard J. Trabulsi
Download or read book Chemotherapy and Immunotherapy in Urologic Oncology written by Edouard J. Trabulsi and published by Springer Nature. This book was released on 2020-09-29 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.
Book Synopsis Clinical Oncology by : Martin D. Abeloff
Download or read book Clinical Oncology written by Martin D. Abeloff and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A must-have reference, this new edition provides practical information on treatment guidelines, details of diagnosis and therapy, and personal recommendations on patient management from experts in the field. Consistently formatted chapters allow for a user-friendly presentation for quick access of key information by the practicing clinician. Completely updated, this new edition includes all of the latest developments in treatment strategies of medical, surgical and radiation oncologists.
Book Synopsis Imaging and Focal Therapy of Early Prostate Cancer by : Thomas J. Polascik
Download or read book Imaging and Focal Therapy of Early Prostate Cancer written by Thomas J. Polascik and published by Springer Science & Business Media. This book was released on 2012-12-02 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy, ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.
Book Synopsis Prostate Cancer by : Ashutosh K. Tewari
Download or read book Prostate Cancer written by Ashutosh K. Tewari and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do you manage patients with prostate cancer? Could you use an expert guide examining all possible management options? Prostate Cancer: diagnosis and clinical management providesurologists and oncologists of all levels with up-to-date, evidence-based guidance to the diagnosis, treatment and clinical management of a disease which accounts for a quarter of all cancers affecting men. Designed to be as practical and accessible as possible, leading experts discuss key issues in prostate cancer management and examine how to deliver best practice in the clinical care of their patients. Topics covered include: What must be considered when counseling newly-diagnosed cancer patients Radical surgery options for prostate cancer Novel therapies for localized prostate cancer How should metastatic prostate cancer be diagnostic and managed What are the best methods of administering end of life care for the patient Brought to you by a highly experienced editor team, and containing key points, management algorithms, practice tips and the latest AUA and EAU clinical guidelines, this is the ideal consultation tool for doctors both on the wards and in the office.
