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Abnormalities Of The Sex Chromosome Complement In Man
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Book Synopsis Abnormalities of the Sex Chromosome Complement in Man by : Medical Research Council (Great Britain)
Download or read book Abnormalities of the Sex Chromosome Complement in Man written by Medical Research Council (Great Britain) and published by . This book was released on 1964 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Abnormalities of the Sex Chromosome Complement in Man by : Medical Research Council
Download or read book Abnormalities of the Sex Chromosome Complement in Man written by Medical Research Council and published by . This book was released on 1964 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Abnormalities of the Sex Chromosome Complement in Man by : William Michael Court Brown
Download or read book Abnormalities of the Sex Chromosome Complement in Man written by William Michael Court Brown and published by . This book was released on 1964 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Special Report Series No. 305 written by and published by . This book was released on 1964 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sex Chromosomes by : Ursula Mittwoch
Download or read book Sex Chromosomes written by Ursula Mittwoch and published by Academic Press. This book was released on 2014-06-28 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex Chromosomes focuses on the study of sex chromosomes, including human chromosomal abnormalities, behavior and characteristics of chromosomes, and cell division. The book first offers information on the chromosomal basis of sex determination, as well as development of the cell theory, mitosis, fertilization, meiosis, and discovery of sex chromosomes. The publication also ponders on the mitosis, meiosis, and formation of gametes. Discussions focus on the special characteristics of sex chromosomes, abnormalities of cell division, and sexual differentiation. The manuscript reviews sex chromosomes in plants, Drosophila, and Lepidoptera. The book also examines sex-chromosome mechanisms that differ the classic type; sex chromosomes in fishes, amphibia, reptiles, and birds; and sex chromosomes in man. Discussions focus on normal human sex chromosomes, Turner's syndrome, Klinefelter's syndrome, true hermaphrodites, testicular feminization, and pseudohermaphrodites. Sex chromosomes in mammals other than man, including monotremata, marsupialia, insectivora, rodentia, and carnivora, are discussed. The publication is a dependable reference for readers interested in the study of sex chromosomes.
Book Synopsis The Sex Chromosome Complement is an Important Determinant in Obesity and Related Diseases by : Jenny Chen Link
Download or read book The Sex Chromosome Complement is an Important Determinant in Obesity and Related Diseases written by Jenny Chen Link and published by . This book was released on 2015 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is associated with numerous metabolic disorders, including hypertension, hyperlipidemia, insulin resistance, and atherosclerosis. In addition, obesity is a risk factor for cardiovascular disease and cancer, the leading causes of mortality. It is thus critical to understand the environmental and genetic components that contribute to the development of obesity, one of which is sex. The sexual dimorphism in fat accumulation and distribution has been well established for a few decades. Premenopausal women tend to gain fat near the hips and thighs, while men and postmenopausal women tend to accumulate fat in the abdominal cavity. These sex differences have often been attributed to sex hormones, but sex differences in metabolic traits remain long after gonadal hormones have declined. This suggests that factors other than sex hormones could contribute to sex differences in metabolism. The sex chromosome complement is the fundamental difference between male and female cells. Because XX chromosomes often coexist with ovaries and XY chromosomes are coupled with testes, the distinct effects of gonadal type and sex chromosomes are difficult to distinguish. A unique mouse model called the Four Core Genotypes (FCG) generates XX female, XX male, XY female, and XY male mice, and is an innovative tool to study effects of the sex chromosome complement (XX male/female vs. XY male/female) independently from effects of gonadal hormones (XX/XY male vs. XX/XY female). We used FCG mice to study sex differences in obesity and related metabolic disorders. We compared gonadally intact mice with gonadectomized mice to assess acute effects of gonadal hormones, and we nutritionally challenged mice with a high fat diet and a high cholesterol diet to identify diet-sex interactions. Male and female mice with two X chromosomes gain more weight, have increased adiposity, and accumulate more hepatic lipid compared to XY mice. In addition, XX mice have increased HDL cholesterol levels, regardless of the dietary or hormone milieu. Sex chromosome differences were also detected at the molecular level, modulating mRNA and microRNA expression. Our studies demonstrate that the sex chromosome complement is a major determinant of body weight, adiposity, and associated metabolic traits such as hepatic lipid and plasma lipid levels. The key findings from this dissertation will shed light on sex differences in obesity and are important for improving prevention and treatment of metabolic disease.
Book Synopsis Sex Chromosomes by : Cynthia N. Weingarten
Download or read book Sex Chromosomes written by Cynthia N. Weingarten and published by Nova Science Publishers. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex chromosomes determine the sex of an organism. A human somatic cell has two sex chromosomes: XY in male and XX in female. A human germ cell has one sex chromosome: X or Y in a sperm and X in an egg. When an X-sperm is combined with an egg, the resulting zygote (fertilised egg) will contain two X chromosomes. A person developed from the XX-zygote will have the characteristics of a female. Combination of a Y-sperm and an egg will produce a male. Usually, a woman has two X chromosomes (XX) and a man one X and one Y (XY). However, both male and female characteristics can sometimes be found in one individual, and it is possible to have XY women and XX men. Analysis of such individuals has revealed some of the molecules involved in sex determination, including one called SRY, which is important for testis formation. SRY (which stands for sex-determining region Y gene) is found on the Y chromosome. In the cell, it binds to other DNA and in doing so distorts it dramatically out of shape. This alters the properties of the DNA and likely alters the expression of a number of genes, leading to testis formation. Most XX men who lack a Y chromosome do still have a copy of the SRY gene on one of their X chromosomes (moved there by chromosomal translocation). This copy accounts for their maleness. However, because the remainder of the Y chromosome is missing they frequently do not develop secondary sexual characteristics in the usual way. This book presents the latest research in the field from around the world.
Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine
Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Book Synopsis Gardner and Sutherland's Chromosome Abnormalities and Genetic Counseling by : R.J. McKinlay Gardner
Download or read book Gardner and Sutherland's Chromosome Abnormalities and Genetic Counseling written by R.J. McKinlay Gardner and published by Oxford University Press. This book was released on 2018-02-06 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even as classic cytogenetics has given way to molecular karyotyping, and as new deletion and duplication syndromes are identified almost every day, the fundamental role of the genetics clinic remains mostly unchanged. Genetic counselors and medical geneticists explain the "unexplainable," helping families understand why abnormalities occur and whether they're likely to occur again. Chromosome Abnormalities and Genetic Counseling is the genetics professional's definitive guide to navigating both chromosome disorders and the clinical questions of the families they impact. Combining a primer on these disorders with the most current approach to their best clinical approaches, this classic text is more than just a reference; it is a guide to how to think about these disorders, even as our technical understanding of them continues to evolve. Completely updated and still infused with the warmth and voice that have made it essential reading for professionals across medical genetics, this edition of Chromosome Abnormalities and Genetic Counseling represents a leap forward in clinical understanding and communication. It is, as ever, essential reading for the field.
Download or read book MRCOG Part One written by Alison Fiander and published by Cambridge University Press. This book was released on 2016-10-13 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.
Book Synopsis Gigantism and Acromegaly by : Constantine A. Stratakis
Download or read book Gigantism and Acromegaly written by Constantine A. Stratakis and published by Academic Press. This book was released on 2021-06-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Book Synopsis Textbook of Human Reproductive Genetics by : Karen Sermon
Download or read book Textbook of Human Reproductive Genetics written by Karen Sermon and published by Cambridge University Press. This book was released on 2014-04-10 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.
Book Synopsis Genetics for Surgeons by : Patrick John Morrison
Download or read book Genetics for Surgeons written by Patrick John Morrison and published by Remedica. This book was released on 2005 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).
Download or read book Neurogenetics, Part I written by and published by Elsevier. This book was released on 2018-01-08 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist. Presents a comprehensive coverage of neurogenetics Details the latest science and impact on our understanding of neurological psychiatric disorders Provides a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Book Synopsis Chromosome Abnormalities and Genetic Counseling by : R.J. MKinlay Gardner
Download or read book Chromosome Abnormalities and Genetic Counseling written by R.J. MKinlay Gardner and published by OUP USA. This book was released on 2012 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cytogenetics continue to crop up in wonderful ways, and we know exponentially more about chromosomes now than mere decades ago. Likewise, the necessary skills in offering genetic counseling continue to evolve. This new edition of Chromosome Abnormalities in Genetic Counseling offers a practical, up-to-date guide for the genetic counselor to marshal cytogenetic data and analysis clearly and effectively to families.
Book Synopsis High-Quality, High-Volume Spay and Neuter and Other Shelter Surgeries by : Sara White
Download or read book High-Quality, High-Volume Spay and Neuter and Other Shelter Surgeries written by Sara White and published by John Wiley & Sons. This book was released on 2020-01-03 with total page 1014 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference provides veterinarians with everything they need to know about performing surgeries such as spaying and neutering in busy animal shelters. It includes surgical and anesthetic techniques, perioperative procedures, reproductive medicine, and program management regarding dogs, cats, rabbits, and other small mammals. With more than 550 full-color images, High-Quality, High-Volume Spay and Neuter and Other Shelter Surgeries provides spay-neuter and shelter veterinarians with information on the most current clinical techniques. Dozens of veterinary experts offer their expert advice and knowledge on perioperative care, surgery instrumentation, infectious disease control, anesthesia protocols, CPR, the fundamentals of HQHVSN, and more. Covers all aspects of common shelter surgeries, including surgical and anesthetic techniques, perioperative procedures, reproductive medicine, and program management Provides coverage of dogs, cats, rabbits, and other small mammals Written by leaders in the field with experience in surgery, medicine, spay-neuter practice, teaching, and research High-Quality, High-Volume Spay and Neuter and Other Shelter Surgeries is an excellent resource for veterinarians, veterinary technicians, and students, as well as clinic and shelter owners.
Book Synopsis Concepts of Biology by : Samantha Fowler
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
