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Author : Peter J. Munson
Publisher :
ISBN 13 :
Total Pages : 122 pages
Book Rating : 4.3/5 (91 download)
Download or read book A User's Guide to LIGAND written by Peter J. Munson and published by . This book was released on 1987 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sara E. Ingle
Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.3/5 (121 download)
Download or read book A user's guide for REDEQL.EPA written by Sara E. Ingle and published by . This book was released on 1978 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 650 pages
Book Rating : 4.E/5 ( download)
Download or read book Psychopharmacology Bulletin written by and published by . This book was released on 1993 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 1120 pages
Book Rating : 4.:/5 (89 download)
Download or read book Monthly Catalog of United States Government Publications written by and published by . This book was released on with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul J. Marangos
Publisher : Elsevier
ISBN 13 : 0323152805
Total Pages : 384 pages
Book Rating : 4.3/5 (231 download)
Download or read book Brain Receptor Methodologies Pt A written by Paul J. Marangos and published by Elsevier. This book was released on 2012-12-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Receptor Methodologies, Part A, General Methods and Concepts: Amines and Acetylcholine provides information pertinent to neurotransmitter and neuromodulator receptors in brain. This book explores the methodologies that can used to address several basic and clinical problems. Organized into two sections encompassing 18 chapters, this book starts with an overview of the receptor concept, which can be validated from indirect evidence obtained in studies of the quantitative aspects of drug antagonism. This text then examines the radioligand–receptor binding interactions. Other chapters consider immunocytochemistry, which has a primary role in determining the precise distribution of regulatory peptides to neural and endocrine elements of the diffuse neuroendocrine system. The final chapter discusses the use of the radioligand binding procedure for the study of muscarinic receptors, which has expanded the area of muscarinic receptor pharmacology. Biochemists, pharmacologists, physiologists, and researchers engaged in the fields of neurobiology and neuroscience will find this book extremely useful.
Author : Celerino Abad-Zapatero
Publisher : Academic Press
ISBN 13 : 0124046827
Total Pages : 179 pages
Book Rating : 4.1/5 (24 download)
Download or read book Ligand Efficiency Indices for Drug Discovery written by Celerino Abad-Zapatero and published by Academic Press. This book was released on 2013-01-22 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. - Provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery - Emphasizes the use of 'new variables' and more objective numerical methods to drive quicker and more effective drug discovery - Presents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework
Author : United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations
Publisher :
ISBN 13 :
Total Pages : 748 pages
Book Rating : 4.:/5 (51 download)
Download or read book Global Proliferation of Weapons of Mass Destruction written by United States. Congress. Senate. Committee on Governmental Affairs. Permanent Subcommittee on Investigations and published by . This book was released on 1996 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mark S. Gordon
Publisher : John Wiley & Sons
ISBN 13 : 1119129265
Total Pages : 499 pages
Book Rating : 4.1/5 (191 download)
Download or read book Fragmentation: Toward Accurate Calculations on Complex Molecular Systems written by Mark S. Gordon and published by John Wiley & Sons. This book was released on 2017-08-04 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fragmentation: Toward Accurate Calculations on Complex Molecular Systems introduces the reader to the broad array of fragmentation and embedding methods that are currently available or under development to facilitate accurate calculations on large, complex systems such as proteins, polymers, liquids and nanoparticles. These methods work by subdividing a system into subunits, called fragments or subsystems or domains. Calculations are performed on each fragment and then the results are combined to predict properties for the whole system. Topics covered include: Fragmentation methods Embedding methods Explicitly correlated local electron correlation methods Fragment molecular orbital method Methods for treating large molecules This book is aimed at academic researchers who are interested in computational chemistry, computational biology, computational materials science and related fields, as well as graduate students in these fields.
Author : Sara E. Ingle
Publisher :
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4.3/5 (121 download)
Download or read book REDEQL.EPAK written by Sara E. Ingle and published by . This book was released on 1980 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Irving M. Klotz
Publisher : John Wiley & Sons
ISBN 13 : 9780471176268
Total Pages : 196 pages
Book Rating : 4.1/5 (762 download)
Download or read book Ligand-Receptor Energetics written by Irving M. Klotz and published by John Wiley & Sons. This book was released on 1997-03-14 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Energetische Wechselbeziehungen zwischen Ligand und Rezeptor sind besonders bei der Wechselwirkung kleiner Moleküle mit größeren unter Bildung komplexer Makromoleküle von Bedeutung, welche eine essentielle Rolle in Chemie, Biochemie, Biophysik, Pharmakologie und vielen anderen Gebieten spielen. Hier werden die thermodynamischen Ansätze experimentell und theoretisch erläutert - mit vielen Illustrationen zur Erklärung der Ligand-Bindungskonzepte.
Author : Alfredo Ricci
Publisher : John Wiley & Sons
ISBN 13 : 3527347399
Total Pages : 480 pages
Book Rating : 4.5/5 (273 download)
Download or read book Methodologies in Amine Synthesis written by Alfredo Ricci and published by John Wiley & Sons. This book was released on 2021-04-26 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover a comprehensive overview of efficient synthetic routes to an important compound class in organic and pharmaceutical chemistry Methodologies in Amine Synthesis: Challenges and Applications delivers powerful and state-of-the-art methods for the efficient preparation of amines. The text summarizes recent advances in the electrophilic amination reaction, hydroamination, C-H amination and newly developed photocatalytic approaches. The distinguished editor has included resources that discuss organocatalytic and enzymatic routes to the generation of amines under mild and environmentally friendly conditions. The book also highlights the relevance of the amino function in bioactive molecules, drugs, and smart materials, as well as the palladium-catalyzed aromatic amination reaction. It presents efficient and practical synthetic methods, highlights the opportunities and challenges associated with each, and discusses their possible applications in pharmaceutical chemistry and materials science. Edited by the expert who wrote Modern Amination Methods and Amino Group Chemistry, the book includes a breadth and depth of material essential to the practice of academic and industrial chemists working in organic synthesis and catalysis. Readers will also benefit from the inclusion of: A thorough introduction to new openings and perspectives in the electrophilic amination Discussions of asymmetric catalysed hydroaminomethylation and amino organocatalysis A treatment of the synthetic application of transaminase or MAO biocatalysis to the synthesis of amines An exploration of recent developments in C-H amination, as well as photocatalytic approaches to the synthesis of amines An examination of primary amines from renewable bio-based resources Perfect for organic, natural product, catalytic, medicinal, and polymer chemists, Methodologies in Amine Synthesis: Challenges and Applications will also earn a place in the libraries of materials scientists and chemists working with organometallics who desire a one-stop reference edited by a well-known expert in the field.
Author :
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.3/5 (243 download)
Download or read book Ecological Research Series written by and published by . This book was released on 1978 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Warren J. Hehre
Publisher :
ISBN 13 : 9781890661038
Total Pages : 210 pages
Book Rating : 4.6/5 (61 download)
Download or read book PC Spartan Plus Tutorial and User's Guide, Version 1.0 written by Warren J. Hehre and published by . This book was released on 1997-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Armin de Meijere
Publisher : John Wiley & Sons
ISBN 13 : 3527655603
Total Pages : 1640 pages
Book Rating : 4.5/5 (276 download)
Download or read book Metal Catalyzed Cross-Coupling Reactions and More written by Armin de Meijere and published by John Wiley & Sons. This book was released on 2013-12-04 with total page 1640 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three volume book is the follow-up handbook to the bestselling volume "Metal-Catalyzed Cross-Coupling Reactions", the definitive reference in the field. In line with the enormous developments in this area, this is not a new edition, but rather a new book in three volumes with over 50% more content. This new content includes C-H activation, shifting the focus away from typical cross-coupling reactions, while those topics and chapters found in de Meijere/Diederich's book have been updated and expanded. With its highly experienced editor team and the list of authors reading like an international Who's-Who in the field, this work will be of great interest to every synthetic chemist working in academia and industry.
Author : Wavefunction, Incorporated
Publisher :
ISBN 13 : 9781890661090
Total Pages : 116 pages
Book Rating : 4.6/5 (61 download)
Download or read book PC Spartan Pro User's Guide written by Wavefunction, Incorporated and published by . This book was released on 1999-03 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ryohei Yamaguchi
Publisher : John Wiley & Sons
ISBN 13 : 1118203518
Total Pages : 358 pages
Book Rating : 4.1/5 (182 download)
Download or read book Ligand Platforms in Homogenous Catalytic Reactions with Metals written by Ryohei Yamaguchi and published by John Wiley & Sons. This book was released on 2014-11-17 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serving as a user's manual for synthetic organic and catalytic chemists, this book guides chemists in the design and choice of ligands to catalyze organic reactions and apply the results for more efficient, green, and practical synthesis. • Focuses on the role of ligands in metal complexes that catalyze green organic transformations: a hot topic in the area of organic synthesis and green chemistry • Offers a comprehensive resource to help readers design and choose ligands and understand selectivity/reactivity characteristics • Addresses a gap by taking novel ligand approaches and including up-to-date discussion on hydrogen transfers and reactions • Presents important industrial perspective and provides rational explanations of ligand effects, impacts, and novelty
Author : Gale Rhodes
Publisher : Academic Press
ISBN 13 : 0323137784
Total Pages : 217 pages
Book Rating : 4.3/5 (231 download)
Download or read book Crystallography Made Crystal Clear written by Gale Rhodes and published by Academic Press. This book was released on 2012-12-02 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists.Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science backgroundLeads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallographyExplains how to read crystallography papers in research journalsIf you use computer-generated models of proteins or nucleic acids for:Studying molecular interactionsDesigning ligands, inhibitors, or drugsEngineering new protein functionsInterpreting chemical, kinetic, thermodynamic, or spectroscopic dataStudying protein foldingTeaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.
