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Author : William B. Blesser
Publisher :
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)
Download or read book A Systems Approach to Biomedicine written by William B. Blesser and published by . This book was released on 1969 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William B. Blesser
Publisher :
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)
Download or read book A Systems Approach to Biomedicine written by William B. Blesser and published by . This book was released on 1969 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas Deisboeck
Publisher : Springer Science & Business Media
ISBN 13 : 0387335323
Total Pages : 857 pages
Book Rating : 4.3/5 (873 download)
Download or read book Complex Systems Science in Biomedicine written by Thomas Deisboeck and published by Springer Science & Business Media. This book was released on 2007-06-13 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.
Author : Edison T. Liu
Publisher : Academic Press
ISBN 13 : 0080919839
Total Pages : 450 pages
Book Rating : 4.0/5 (89 download)
Download or read book Systems Biomedicine written by Edison T. Liu and published by Academic Press. This book was released on 2009-09-17 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable Includes a thorough discussion of the applications of quantitative principles to biomedical problems
Author : Robert S. Cutler
Publisher : Forgotten Books
ISBN 13 : 9780483293823
Total Pages : 86 pages
Book Rating : 4.2/5 (938 download)
Download or read book Project Soap written by Robert S. Cutler and published by Forgotten Books. This book was released on 2018-03-20 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Project Soap: A Systems Approach to Biomedical Research Program Management; A Case Study A procedure which organizes relevant information for research program planning and evaluation is presented, and extension of this recommended procedure to wider use by science administrators elsewhere in govern ment is discussed. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Author : Robert S.. Cutler
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.:/5 (245 download)
Download or read book Project SOAP written by Robert S.. Cutler and published by . This book was released on 1973 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William Hersh
Publisher : Springer Science & Business Media
ISBN 13 : 0387226788
Total Pages : 524 pages
Book Rating : 4.3/5 (872 download)
Download or read book Information Retrieval written by William Hersh and published by Springer Science & Business Media. This book was released on 2006-05-04 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coupled with the growth of the World Wide Web, the topic of health information retrieval has had a tremendous impact on consumer health information. With the aid of newly added questions and discussions at the end of each chapter, this Second Edition covers theory practical applications, evaluation, and research directions of all aspects of medical information retireval systems.
Author : Ian Lyons
Publisher : John Wiley & Sons
ISBN 13 : 1118294718
Total Pages : 560 pages
Book Rating : 4.1/5 (182 download)
Download or read book Biomedical Science written by Ian Lyons and published by John Wiley & Sons. This book was released on 2011-11-16 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brand new Lecture Notes title provides the core biomedical science study and revision material that medical students need to know. Matching the common systems-based approach taken by the majority of medical schools, it provides concise, student-led content that is rooted in clinical relevance. The book is filled with learning features such as key definitions and key conditions, and is cross-referenced to develop interdisciplinary awareness. Although designed predominantly for medical students, this new Lecture Notes book is also useful for students of dentistry, pharmacology and nursing. Biomedical Science Lecture Notes provides: A brand new title in the award-winning Lecture Notes series A concise, full colour study and revision guide A 'one-stop-shop' for the biomedical sciences Clinical relevance and cross referencing to develop interdisciplinary skills Learning features such as key definitions to aid understanding
Author : Lani Russell
Publisher : SAGE
ISBN 13 : 1446292827
Total Pages : 387 pages
Book Rating : 4.4/5 (462 download)
Download or read book Sociology for Health Professionals written by Lani Russell and published by SAGE. This book was released on 2013-11-28 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sociology is a key topic for all trainee health professionals, but many struggle to see what sociology has to offer. Based on years of experience teaching sociology to healthcare students, Lani Russell has written a truly introductory text which explains the main sociological concepts without jargon or becoming too advanced. Using carefully chosen examples, she shows how health issues are influenced by social phenomena such as class, race or sexuality and the relevance this has for practitioners. The book includes: -The main sociological concepts relevant to healthcare students -Examples linking sociological concepts and major health topics -Exercises to test students′ understanding -Glossaries of key terms and key theorists -Advice on further reading -A full companion website with teaching materials for lecturers and learning resources for students This is the ideal text to recommend to students who need an accessible introduction to the sociology of health and illness.
Author : Shailza Singh
Publisher : Springer Nature
ISBN 13 : 9811919534
Total Pages : 170 pages
Book Rating : 4.8/5 (119 download)
Download or read book Systems Biomedicine Approaches in Cancer Research written by Shailza Singh and published by Springer Nature. This book was released on 2022-08-10 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the applications of systems biology and synthetic biology in cancer medicine. It highlights the use of computational and mathematical models to decipher the complexity of cancer heterogeneity. The book emphasizes the modeling approaches for predicting behavior of cancer cells, tissues in context of drug response, and angiogenesis. It introduces cell-based therapies for the treatment of various cancers and reviews the role of neural networks for drug response prediction. Further, it examines the system biology approaches for the identification of medicinal plants in cancer drug discovery. It explores the opportunities for metabolic engineering in the realm of cancer research towards development of new cancer therapies based on metabolically derived targets. Lastly, it discusses the applications of data mining techniques in cancer research. This book is an excellent guide for oncologists and researchers who are involved in the latest cancer research.
Author :
Publisher :
ISBN 13 :
Total Pages : 75 pages
Book Rating : 4.:/5 (966 download)
Download or read book Project SOAP, Systems Approach to Biomedical Research Program Management written by and published by . This book was released on 1973 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael G. Sargent
Publisher : Cambridge University Press
ISBN 13 : 9781139443937
Total Pages : 376 pages
Book Rating : 4.4/5 (439 download)
Download or read book Biomedicine and the Human Condition written by Michael G. Sargent and published by Cambridge University Press. This book was released on 2005-02-28 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to avoid disease, how to breed successfully and how to live to a reasonable age, are questions that have perplexed mankind throughout history. This 2005 book explores our progress in understanding these challenges, and the risks and rewards of our attempts to find solutions. From the moment of conception, nutrition and exposure to microbes or alien chemicals have consequences that are etched into our cells and genomes. Such events have a crucial impact on development in utero and in childhood, and later, on the way we age, respond to infection, or the likelihood of developing chronic diseases, including cancer. The issues covered include the powerful influence of infectious disease on human society, the burden of our genetic legacy and the lottery of procreation. The author discusses how prospects for human life might continually improve as biomedicine addresses these problems and also debates the ethical checkpoints encountered.
Author : Mariano Bizzarri
Publisher : Springer Nature
ISBN 13 : 3030328570
Total Pages : 493 pages
Book Rating : 4.0/5 (33 download)
Download or read book Approaching Complex Diseases written by Mariano Bizzarri and published by Springer Nature. This book was released on 2020-04-17 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
Author : Edwin L. Cooper
Publisher : Springer Science & Business Media
ISBN 13 : 9780306482885
Total Pages : 514 pages
Book Rating : 4.4/5 (828 download)
Download or read book Complementary and Alternative Approaches to Biomedicine written by Edwin L. Cooper and published by Springer Science & Business Media. This book was released on 2004-09-23 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the proceedings of an international symposium that examined the newest parameters in alternative and complementary medicine, thus covering a rapidly growing field of medicine that has strong advocates as well as strong opponents. Topics include both basic research and clinical applications, allowing the text to present high quality, peer reviewed, chapter style contributions that dispel some of the pseudoscience and myth surrounding alternative and complimentary medicine.
Author : Pietro Lio
Publisher : Frontiers E-books
ISBN 13 : 2889193748
Total Pages : 114 pages
Book Rating : 4.8/5 (891 download)
Download or read book Comprehensive Systems Biomedicine written by Pietro Lio and published by Frontiers E-books. This book was released on 2014-12-03 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biomedicine is a field in perpetual development. By definition a translational discipline, it emphasizes the role of quantitative systems approaches in biomedicine and aims to offer solutions to many emerging problems characterized by levels and types of complexity and uncertainty unmet before. Many factors, including technological and societal ones, need to be considered. In particular, new technologies are providing researchers with the data deluge whose management and exploitation requires a reinvention of cross-disciplinary team efforts. The advent of “omics” and high-content imaging are examples of advances de facto establishing the necessity of systems approaches. Hypothesis-driven models and in silico validation tools in support to all the varieties of experimental applications call for a profound revision. The focus on phases like mining and assimilating the data has substantially increased so to allow for interpretable knowledge to be inferred. Notably, to be able to tackle the newly generated data dimensionality, heterogeneity and complexity, model-free and data-driven intensive applications are increasingly shaping the computational pipelines and architectures that quant specialists set aside of the high-throughput genomics, transcriptomics, proteomics platforms. As for the societal aspects, in many advanced societies health care needs now more than in the past to address the problem of managing ageing populations and their complex morbidity patterns. In parallel, there is a growing research interest on the impact that cross-disciplinary clinical, epidemiological and quantitative modelling studies can have in relation to outcomes potentially affecting the quality of life of many people. Complex systems, including those characterizing biomedicine, are assessed in both their functionality and stability, and also relatively to the capacity of generating information from diversity, variation, and complexity. Due to the combined interactions and effects, such systems embed prediction power available for instance in both target identification or marker discovery, or more generally for conducting inference about patients’ pathological states, i.e. normal versus disease, diagnostic or prognostic analysis, and preventive assessment (e.g., risk evaluation). The ultimate goal, personalized medicine, will be achieved based on the confluence of the system’s predictive power to patient-specific profiling.
Author : Merrill Singer
Publisher : John Wiley & Sons
ISBN 13 : 0470483008
Total Pages : 418 pages
Book Rating : 4.4/5 (74 download)
Download or read book Introduction to Syndemics written by Merrill Singer and published by John Wiley & Sons. This book was released on 2009-06-03 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the growing field of syndemic theory and research, a framework for the analysis and prevention of disease interactions that addresses underlying social and environmental causes. This perspective complements single-issue prevention strategies, which can be effective for discrete problems, but often are mismatched to the goal of protecting the public's health in its widest sense. "Merrill Singer has astutely described why health problems should not be seen in isolation, but rather in the context of other diseases and the social and economic inequities that fuel them. An important read for public health and social scientists." —Michael H. Merson, director, Duke Global Health Institute "Not only does this book provide a persuasive theoretical biosocial model of syndemics, but it also illustrates the model with a wide variety of fascinating historical and contemporary examples." —Peter J. Brown, professor of Anthropology and Global Health and director, Center for Health, Culture, and Society, Emory University "The concept of syndemics is Singer's most important contribution to critical medical anthropology as it interfaces with an ecosocial approach to epidemiology." —Mark Nichter, Regents Professor, Department of Anthropology, University of Arizona "Merrill Singer offers the public the most comprehensive work ever written on this key area of research and policy making." —Francisco I. Bastos, chairman of the graduate studies on epidemiology, Fundacao Oswaldo Cruz "Exquisitely describes how this new approach is a critical tool that brings together veterinary, medical, and social sciences to solve emerging infectious and non-infectious diseases of today's world." —Bonnie Buntain, MS, DVM, diplomate, American College of Veterinary Preventive Medicine "For too long the great integrative perspectives on modern biomedicine and public health disease ecology and social medicine-have remained more or less separate. In this innovative and provocative book, Merrill Singer develops a valuable synthesis that will reshape the way we think about health and disease." —Warwick H. Anderson, MD, PhD, professorial research fellow, Department of History and Centre for Values, Ethics, and the Law in Medicine, University of Sidney
Author : William B. Blesser
Publisher :
ISBN 13 :
Total Pages : 615 pages
Book Rating : 4.:/5 (781 download)
Download or read book A System Approach to Biomedicine written by William B. Blesser and published by . This book was released on 1969 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt:
