A Primer Of Population Genetics And Genomics

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A Primer of Population Genetics and Genomics

Author : Daniel L. Hartl
Publisher : Oxford University Press
ISBN 13 : 0192607049
Total Pages : 272 pages
Book Rating : 4.1/5 (926 download)

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Book Synopsis A Primer of Population Genetics and Genomics by : Daniel L. Hartl

Download or read book A Primer of Population Genetics and Genomics written by Daniel L. Hartl and published by Oxford University Press. This book was released on 2020-06-18 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Primer of Population Genetics and Genomics has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics. Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of current research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention. This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.

A Primer of Population Genetics

Author : Daniel L. Hartl
Publisher : Sinauer Associates, Incorporated
ISBN 13 : 9780878933013
Total Pages : 326 pages
Book Rating : 4.9/5 (33 download)

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Book Synopsis A Primer of Population Genetics by : Daniel L. Hartl

Download or read book A Primer of Population Genetics written by Daniel L. Hartl and published by Sinauer Associates, Incorporated. This book was released on 1988 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of molecular methods to study genetic polymorphisms has made a familiarity with population genetics essential for any biologist whose work is at the population level. A Primer of Population Genetics, Third Edition provides a concise but comprehensive introduction to population genetics. The four chapters of the book address genetic variation, the causes of evolution, molecular population genetics, and the genetic architecture of complex traits. Chapter-end problems reinforce ideas and, while there are some equations, the emphasis is on explanation rather than derivation.

A Primer of Molecular Population Genetics

Author : Asher D. Cutter
Publisher : Oxford University Press, USA
ISBN 13 : 0198838948
Total Pages : 266 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis A Primer of Molecular Population Genetics by : Asher D. Cutter

Download or read book A Primer of Molecular Population Genetics written by Asher D. Cutter and published by Oxford University Press, USA. This book was released on 2019 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

A Primer of Population Genetics and Genomics

Author : Daniel L. Hartl
Publisher :
ISBN 13 : 9780191895074
Total Pages : pages
Book Rating : 4.8/5 (95 download)

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Book Synopsis A Primer of Population Genetics and Genomics by : Daniel L. Hartl

Download or read book A Primer of Population Genetics and Genomics written by Daniel L. Hartl and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.

A Primer of Molecular Population Genetics

Author : Asher D. Cutter
Publisher : Oxford University Press
ISBN 13 : 0192575546
Total Pages : 266 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis A Primer of Molecular Population Genetics by : Asher D. Cutter

Download or read book A Primer of Molecular Population Genetics written by Asher D. Cutter and published by Oxford University Press. This book was released on 2019-06-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

A Primer of Ecological Genetics

Author : Jeffrey K. Conner
Publisher : Sinauer Associates Incorporated
ISBN 13 : 9780878932023
Total Pages : 304 pages
Book Rating : 4.9/5 (32 download)

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Book Synopsis A Primer of Ecological Genetics by : Jeffrey K. Conner

Download or read book A Primer of Ecological Genetics written by Jeffrey K. Conner and published by Sinauer Associates Incorporated. This book was released on 2004-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers basic concepts in population and quantitative genetics, including measuring selection on phenotypic traits. The emphasis is on material applicable to field studies of evolution focusing on ecologically important traits. Topics addressed are critical for training students in ecology, evolution, conservation biology, agriculture, forestry, and wildlife management. Many texts in this field are too complex and mathematical to allow the average beginning student to readily grasp the key concepts. A Primer of Ecological Genetics, in contrast, employs mathematics and statistics-fully explained, but at a less advanced level-as tools to improve understanding of biological principles. The main goal is to enable students to understand the concepts well enough that they can gain entry into the primary literature. Integration of the different chapters of the book shows students how diverse concepts relate to each other.

Molecular Population Genetics

Author : Matthew William Hahn
Publisher : Sinauer Associates, Incorporated
ISBN 13 : 9780878939657
Total Pages : 334 pages
Book Rating : 4.9/5 (396 download)

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Book Synopsis Molecular Population Genetics by : Matthew William Hahn

Download or read book Molecular Population Genetics written by Matthew William Hahn and published by Sinauer Associates, Incorporated. This book was released on 2018 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published by Sinauer Associates, an imprint of Oxford University Press. Provides descriptions of the methods and tools used in molecular population genetics, which has combined advances in molecular biology and genomics with mathematical and empirical findings to uncover the history of natural selection and demographic shifts in many organisms.

Population Genetics

Author : John H. Gillespie
Publisher : JHU Press
ISBN 13 : 0801880084
Total Pages : 263 pages
Book Rating : 4.8/5 (18 download)

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Book Synopsis Population Genetics by : John H. Gillespie

Download or read book Population Genetics written by John H. Gillespie and published by JHU Press. This book was released on 2004-08-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

Population Genetics

Author : Matthew B. Hamilton
Publisher : John Wiley & Sons
ISBN 13 : 1444362453
Total Pages : 658 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Population Genetics by : Matthew B. Hamilton

Download or read book Population Genetics written by Matthew B. Hamilton and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Conservation and the Genomics of Populations

Author : Fred W. Allendorf
Publisher : Oxford University Press
ISBN 13 : 0198856563
Total Pages : 785 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Conservation and the Genomics of Populations by : Fred W. Allendorf

Download or read book Conservation and the Genomics of Populations written by Fred W. Allendorf and published by Oxford University Press. This book was released on 2022 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relentless loss of biodiversity is among the greatest problems facing the world today. The third edition of this established textbook provides an updated and comprehensive overview of the essential background, concepts, and tools required to understand how genetics can be used to conservespecies, reduce threat of extinction, and manage species of ecological or commercial importance. This edition is thoroughly revised to reflect the major contribution of genomics to conservation of populations and species. It includes two new chapters: "Genetic Monitoring" and a final "ConservationGenetics in Practice" chapter that addresses the role of science and policy in conservation genetics.New genomic techniques and statistical analyses are crucial tools for the conservation geneticist. This accessible and authoritative textbook provides an essential toolkit grounded in population genetics theory, coupled with basic and applied research examples from plants, animals, and microbes. Thebook examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, evolutionary response to anthropogenic change, and applications in conservation and management.Conservation and the Genomics of Populations helps demystify genetics and genomics for conservation practitioners and early career scientists, so that population genetic theory and new genomic data can help raise the bar in conserving biodiversity in the most critical 20 year period in the historyof life on Earth. It is aimed at a global market of applied population geneticists, conservation practitioners, and natural resource managers working for wildlife and habitat management agencies. It will be of particular relevance and use to upper undergraduate and graduate students taking coursesin conservation biology, conservation genetics, and wildlife management.

Evolutionary Genetics

Author : Glenn-Peter Sætre
Publisher : Oxford University Press, USA
ISBN 13 : 0198830912
Total Pages : 327 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Evolutionary Genetics by : Glenn-Peter Sætre

Download or read book Evolutionary Genetics written by Glenn-Peter Sætre and published by Oxford University Press, USA. This book was released on 2019-05 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. The book also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Furthermore, at the end of each chapter, study questions are provided to motivate the reader to think and reflect on the concepts introduced. Practical experience is essential when it comes to developing an understanding of how to use genetic and genomic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and the analysis of evolutionary genetic data. The R environment stands out as an ideal all-purpose, open source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.

A Primer of Genome Science IRL

Author : Greg Gibson
Publisher : Sinauer
ISBN 13 : 9780878932368
Total Pages : 0 pages
Book Rating : 4.9/5 (323 download)

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Book Synopsis A Primer of Genome Science IRL by : Greg Gibson

Download or read book A Primer of Genome Science IRL written by Greg Gibson and published by Sinauer. This book was released on 2009-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible introduction to the field of genome science, it explains bioinformatic principles and experimental strategies alongside experimental methods. This edition has been updated to include the latest developments in next generation sequencing, high-volume genotyping and expression profiling, and advances in metabolomics.

Conservation and the Genetics of Populations

Author : Fred W. Allendorf
Publisher : John Wiley & Sons
ISBN 13 : 0470671459
Total Pages : 636 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Conservation and the Genetics of Populations by : Fred W. Allendorf

Download or read book Conservation and the Genetics of Populations written by Fred W. Allendorf and published by John Wiley & Sons. This book was released on 2012-12-17 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at: www.wiley.com/go/allendorf/populations.

Bioinformatics for Geneticists

Author : Michael R. Barnes
Publisher : John Wiley & Sons
ISBN 13 : 047086219X
Total Pages : 432 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Bioinformatics for Geneticists by : Michael R. Barnes

Download or read book Bioinformatics for Geneticists written by Michael R. Barnes and published by John Wiley & Sons. This book was released on 2003-07-01 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book illustrates the value of bioinformatics, not simply as a set of tools but rather as a science increasingly essential to navigate and manage the host of information generated by genomics and the availability of completely sequenced genomes. Bioinformatics can be used at all stages of genetics research: to improve study design, to assist in candidate gene identification, to aid data interpretation and management and to shed light on the molecular pathology of disease-causing mutations. Written specifically for geneticists, this book explains the relevance of bioinformatics showing how it may be used to enhance genetic data mining and markedly improve genetic analysis.

Principles of Population Genetics

Author : Daniel L. Hartl
Publisher : Sinauer Associates, Incorporated
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Principles of Population Genetics by : Daniel L. Hartl

Download or read book Principles of Population Genetics written by Daniel L. Hartl and published by Sinauer Associates, Incorporated. This book was released on 1989 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Darwinian evolution in mendelian populations. Random genetic drift. Mutation and the neutral theory. Natural selection. Inbreeding and other forms of nonrandom mating. Population subdivision and migration. Molecular population genetics. Evolutionary genetics of quantitative characters. Ecological genetics and speciation.

Introduction to Evolutionary Genomics

Author : Naruya Saitou
Publisher : Springer Science & Business Media
ISBN 13 : 1447153049
Total Pages : 476 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Introduction to Evolutionary Genomics by : Naruya Saitou

Download or read book Introduction to Evolutionary Genomics written by Naruya Saitou and published by Springer Science & Business Media. This book was released on 2014-01-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

An Introduction to Statistical Genetic Data Analysis

Author : Melinda C. Mills
Publisher : MIT Press
ISBN 13 : 0262357445
Total Pages : 433 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis An Introduction to Statistical Genetic Data Analysis by : Melinda C. Mills

Download or read book An Introduction to Statistical Genetic Data Analysis written by Melinda C. Mills and published by MIT Press. This book was released on 2020-02-18 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.