A Multidisciplinary Look At Stenotrophomonas Maltophilia An Emerging Multi Drug Resistant Global Opportunistic Pathogen

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A Multidisciplinary Look at Stenotrophomonas maltophilia: An Emerging Multi-Drug-Resistant Global Opportunistic Pathogen

Author : Joanna S. Brooke
Publisher : Frontiers Media SA
ISBN 13 : 2889453537
Total Pages : 135 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis A Multidisciplinary Look at Stenotrophomonas maltophilia: An Emerging Multi-Drug-Resistant Global Opportunistic Pathogen by : Joanna S. Brooke

Download or read book A Multidisciplinary Look at Stenotrophomonas maltophilia: An Emerging Multi-Drug-Resistant Global Opportunistic Pathogen written by Joanna S. Brooke and published by Frontiers Media SA. This book was released on 2017-12-12 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stenotrophomonas maltophilia is a Gram-negative bacterium found in water, plant rhizospheres, animals, and foods. It is associated with a variety of infections in humans, involving respiratory tract (most common), soft tissue and bone, blood, eye, heart, and brain. This opportunistic pathogen is of serious concern to the immunocompromised patient population, and it is also being isolated with increasing frequency from the respiratory tract of individuals with cystic fibrosis. The observed increase worldwide in antibiotic resistance and the ability of this organism to make biofilms on epithelial cells and medical devices make it difficult for health-care personnel to treat infections caused by this pathogen. Recently, several genomes of S. maltophilia have been sequenced, revealing high genetic diversity among isolates. This pathogen uses a variety of molecular mechanisms to acquire and demonstrate resistance to an impressive array of antimicrobial drugs. Research has also focused on the pathogenesis of S. maltophilia in animal models and the resulting host immune response. S. maltophilia is recognized as an important organism in the plant microbiome. This environmental bacterium uses a diffusible signal mechanism for controlling its colonization and interaction with other bacteria and plants. S. maltophilia has also gained considerable research interest for its biotechnological applications, with recent studies on enzyme production, anti-biofilm strategies, biodegradation, and bioremediation. This e-book focuses on the latest developments in the areas of physiology, genomics, infection and immunity, host-pathogen interaction, pathogenesis, antimicrobial resistance and therapy, molecular epidemiology, applied and environmental microbiology, bioremediation and biotechnology.

The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life

Author : Tatiana Venkova
Publisher : Frontiers Media SA
ISBN 13 : 2889455742
Total Pages : 518 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life by : Tatiana Venkova

Download or read book The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life written by Tatiana Venkova and published by Frontiers Media SA. This book was released on 2018-10-17 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readily measured processes and effects on higher organisms. Although molecular genetics and microbiology were among the scientific fields that have mostly benefited from the discoveries made in bacteria, our current state of knowledge has gone beyond what anyone could have ever imagined. The present Research Topic aims to cover new and exciting broad aspects of the importance of bacteria to human life, both positive and negative influences. Regulation of bacterial gene expression, replication and segregation control mechanisms, cell to cell communication via quorum sensors, and the relatively recent finding of bacterial immunity via CRISPR, have led to the development of many, and very important new tools in biotechnology and the emerging field of molecular medicine. The battle against infectious diseases has also benefited from the genetic approaches that have been developed in the quest for finding new targets and novel drugs against pathogenic bacteria. At the next level, the human microbiome project has opened up new avenues in understanding the role of bacteria in human health and wellbeing. Finally, the relationship between bacterial infections and human cancers will also be covered, a subject that is still under verification through rigorous experimental approaches. Special emphasis will be given to the bacterial accessory genome, i.e the mobilome, as the primary cause of health-threatening antimicrobial resistance and the production of toxins and virulence factors. Taking into account the evolutionary importance of horizontal gene transfer and the additional beneficial roles of certain bacterial mobile genetic elements, they help project best “the Good, the Bad and the Ugly” outline of this topic. At the time this eBook is about to be published, our Research Topic has registered nearly 55, 000 views.

Vaginal microecological disorder and gynecological diseases

Author : Zhangran Chen
Publisher : Frontiers Media SA
ISBN 13 : 2832538371
Total Pages : 188 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Vaginal microecological disorder and gynecological diseases by : Zhangran Chen

Download or read book Vaginal microecological disorder and gynecological diseases written by Zhangran Chen and published by Frontiers Media SA. This book was released on 2023-11-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aquatic one health—the intersection of marine wildlife health, public health, and our oceans

Author : Stephanie Norman
Publisher : Frontiers Media SA
ISBN 13 : 2832527426
Total Pages : 130 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Aquatic one health—the intersection of marine wildlife health, public health, and our oceans by : Stephanie Norman

Download or read book Aquatic one health—the intersection of marine wildlife health, public health, and our oceans written by Stephanie Norman and published by Frontiers Media SA. This book was released on 2023-06-30 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Beneficial Microbes Alleviate Climatic Stresses in Plants

Author : Ying Ma
Publisher : Frontiers Media SA
ISBN 13 : 2889459241
Total Pages : 117 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Beneficial Microbes Alleviate Climatic Stresses in Plants by : Ying Ma

Download or read book Beneficial Microbes Alleviate Climatic Stresses in Plants written by Ying Ma and published by Frontiers Media SA. This book was released on 2019-07-30 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic addresses the mechanisms by which beneficial soil microbes, such as fungi and bacteria, protect their host plant from ‘climatic stresses’ that are increasing due to climate change. We will highlight 1) recent progress in fundamental research, 2) applied studies aimed at promoting sustainable agriculture and environmental remediation, and 3) emerging biotechnologies that promote crop adaptation to climate change. Plants respond to various climatic stresses such as drought, salinity, elevated CO2, and extreme temperatures. These responses induce changes at the molecular, cellular, and physiological levels that restrict the establishment, growth, and development of the plant. Understanding these changes has become an important research goal due to concerns about the adverse effects of climatic stresses on agriculture sustainability, global food security, and even plant-based remediation technologies. Some beneficial soil microorganisms, such as arbuscular mycorrhizal fungi and plant growth promoting bacteria, are able to protect and promote the growth of their host plants by acting as bioprotectants (via induced systemic resistance), biopesticides (via antibiotic functions) and phytostimulators (via triggering hormonal signaling networks). Plant adaptation to various climatic stresses is dynamic and involves complex cross-talk within the regulatory network (e.g. transcription factors, kinase cascades, and signaling molecules). However, the detailed molecular, cellular and physiological mechanisms underlying plant–beneficial microbe interactions in climatic stress adaptation remain largely unknown.

Microbial Threats to Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309185548
Total Pages : 397 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Threats to Health by : Institute of Medicine

Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Antimicrobial Resistance

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309060842
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Antimicrobial Resistance by : Institute of Medicine

Download or read book Antimicrobial Resistance written by Institute of Medicine and published by National Academies Press. This book was released on 1998-06-13 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly worrisome situation, however, because resistance is growing and accelerating while the world's tools for combating it decrease in power and number. In addition, the cost of the problemâ€"especially of multidrug resistanceâ€"in terms of money, mortality, and disability are also rising. This book summarizes a workshop on antimicrobial resistance held by the Forum on Emerging Infections. The goal of the Forum on Emerging Infections is to provide an opportunity for representatives of academia, industry, government, and professional and interest groups to examine and discuss scientific and policy dilemmas of common interest that are specifically related to research on and the prevention, detection, and management of emerging infections. Organized as a topic-by-topic synthesis of presentations and exchanges during the workshop, the book highlights lessons learned, delineates a range of pivotal issues and the problems they raise, and proposes some simplified ideas about possible responses.

MRCOG Part One

Author : Alison Fiander
Publisher : Cambridge University Press
ISBN 13 : 1107667135
Total Pages : 557 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis MRCOG Part One by : Alison Fiander

Download or read book MRCOG Part One written by Alison Fiander and published by Cambridge University Press. This book was released on 2016-10-13 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.

Surgical Intensive Care Medicine

Author : John M. O'Donnell
Publisher : Springer Science & Business Media
ISBN 13 : 0387778934
Total Pages : 711 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Surgical Intensive Care Medicine by : John M. O'Donnell

Download or read book Surgical Intensive Care Medicine written by John M. O'Donnell and published by Springer Science & Business Media. This book was released on 2009-11-18 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are honored to present the second edition of Surgical Intensive Care Medicine. Our first edition was considered to be an important contribution to the critical care literature and received excellent reviews from Critical Care Medicine, Chest, and Anesthesiology. In the second edition, the basic organization of the book remains unchanged, being composed of 60 carefully selected chapters divided into 11 sections. The book begins with general topics in primary intensive care, such as airway management and vascular cannulation, followed by categories based on medical and surgical subspecialties. While the chapters discuss definitions, pathophysiology, clinical course, complications, and prognosis, the primary emphasis is devoted to patient management. The contents of the current edition have been comprehensively upgraded and the chapters retained from the first edition have been thoroughly updated, revised, or rewritten. In this second edition, some new topics have been added including Postoperative Care of the Obese Patient, Postoperative Care of the Pancreas Transplant Patient, Optimization of High-Risk Surgical Patients, Post- erative Alcohol Withdrawal Syndrome, Ethics and End of Life Issues, Improving the ICU, and Continuous Medical Education in Intensive Care Medicine. We are extremely fortunate to have high-quality contributors, many of whom are nationally and internationally recognized researchers, speakers, and practitioners in Cri- cal Care Medicine. An important feature of this latest edition is the geographical diversity of its authors. Most are based in the United States, but colleagues from Canada, England, Ireland, Germany, Belgium, Holland, France, Italy, Portugal, and Australia have also made notable contributions.

New edge of antibiotic development: antimicrobial peptides and corresponding resistance

Author : Octavio L. Franco
Publisher : Frontiers E-books
ISBN 13 : 2889193012
Total Pages : 145 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis New edge of antibiotic development: antimicrobial peptides and corresponding resistance by : Octavio L. Franco

Download or read book New edge of antibiotic development: antimicrobial peptides and corresponding resistance written by Octavio L. Franco and published by Frontiers E-books. This book was released on 2014-09-26 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial peptides, commonly isolated from several organisms, have been considered part of innate immune system and also as potential antimicrobial drugs. Besides its antimicrobial activity, some AMPs also have antifungal activity, inmmunomodulatory and antitumural activities. Lately not only nature has become a source of AMPs. Besides isolation of natural organisms, antimicrobial peptides might be improved or created using computational tools. This opens even more this so amazing field by creating infinite novel and remarkable possibilities. Overall the current issue highlights the relevance of such Research Topic with perspectives to develop entirely new molecules with vast application within health and agricultural field with higher affinity for its target with concomitant reduction of side effects.

Tackling Wasteful Spending on Health

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264266410
Total Pages : 306 pages
Book Rating : 4.2/5 (642 download)

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Book Synopsis Tackling Wasteful Spending on Health by : OECD

Download or read book Tackling Wasteful Spending on Health written by OECD and published by OECD Publishing. This book was released on 2017-01-10 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Countries could potentially spend significantly less on health care with no impact on health system performance, or on health outcomes. This report reviews strategies put in place by countries to limit ineffective spending and waste.

The Perfect Slime

Author : Hans-Curt Flemming
Publisher : IWA Publishing
ISBN 13 : 1780407416
Total Pages : 336 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis The Perfect Slime by : Hans-Curt Flemming

Download or read book The Perfect Slime written by Hans-Curt Flemming and published by IWA Publishing. This book was released on 2016-09-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases

Author : Mahendra Rai
Publisher : Academic Press
ISBN 13 : 0128014717
Total Pages : 341 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases by : Mahendra Rai

Download or read book Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases written by Mahendra Rai and published by Academic Press. This book was released on 2015-05-23 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. - Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases - Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. - Delivers commentary from an international researcher base, providing insights across differing economic statuses - Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer - Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

IFIC Basic Concepts of Infection Control

Author : Candace Friedman
Publisher :
ISBN 13 : 9780955586101
Total Pages : 210 pages
Book Rating : 4.5/5 (861 download)

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Book Synopsis IFIC Basic Concepts of Infection Control by : Candace Friedman

Download or read book IFIC Basic Concepts of Infection Control written by Candace Friedman and published by . This book was released on 2007-01-01 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Evolving Threat of Antimicrobial Resistance

Author : World Health Organization
Publisher :
ISBN 13 : 9789241503181
Total Pages : 0 pages
Book Rating : 4.5/5 (31 download)

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Book Synopsis The Evolving Threat of Antimicrobial Resistance by : World Health Organization

Download or read book The Evolving Threat of Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance development is a natural process of adaption leading to a limited lifespan of antibiotics. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. A crisis has been building up over decades, so that today common and life-threatening infections are becoming difficult or even impossible to treat. It is time to take much stronger action worldwide to avert an ever increasing health and economic burden. A new WHO publication "The evolving threat of antimicrobial resistance--Options for action" describes examples of policy activities that have addressed AMR in different parts of the world. The aim is to raise awareness and to stimulate further coordinated efforts.

Abdominal Sepsis

Author : Massimo Sartelli
Publisher : Springer
ISBN 13 : 3319597043
Total Pages : 404 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Abdominal Sepsis by : Massimo Sartelli

Download or read book Abdominal Sepsis written by Massimo Sartelli and published by Springer. This book was released on 2018-03-20 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with this problem. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations and diverticulitis, Clostridium difficile infection and the role of candida in abdominal sepsis, but also by an extensive discussion of issues including antimicrobial resistance, damage control surgery, principles of antimicrobial therapy, hemodynamic support, adjunctive therapies, and thromboprophylaxis. Abdominal sepsis is the host’s systemic inflammatory response to intra-abdominal infections. It is associated with significant morbidity and mortality rates, and represents the second most common cause of sepsis-related mortality at intensive care units. Gathering contributions by authoritative experts from all around the world, this book will allow acute care surgeons, abdominal surgeons, intensive care clinicians, and students to broaden their understanding of intra-abdominal sepsis in daily clinical practice.

Selective Decontamination of the Digestive Tract (SDD)

Author : Hans Rommes
Publisher : Springer Nature
ISBN 13 : 3030652254
Total Pages : 304 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Selective Decontamination of the Digestive Tract (SDD) by : Hans Rommes

Download or read book Selective Decontamination of the Digestive Tract (SDD) written by Hans Rommes and published by Springer Nature. This book was released on 2021-03-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the basic concepts of Selective Decontamination of the Digestive tract (SDD) to help those involved in treating critically ill patients to improve outcomes and the quality of care. SDD has led to major changes in our understanding, the treatment and prevention of infections in critically ill patients over the past 40 years. It is the most studied intervention in intensive care medicine and is the subject of 73 randomized controlled trials, including over 15000 patients and 15 meta-analyses. SDD reduces morbidity and mortality, is cost-effective and safe as SDD does not increase antimicrobial resistance. Correct application of the SDD strategy enables ICU teams to control infections – even in ICUs with endemic antibiotic resistant microorganisms such as methicillin resistant S. aureus (MRSA). Describing the concept and application of SDD, and presenting case studies and microbiological flow charts, this practical guide will appeal to intensivists, critical care practitioners, junior doctors, microbiologists and ICU-nurses as well as infection control specialists and pharmacists.