A Multicenter Prospective Randomized Clinical Trial Assessing Implant Design Modifications After 3 Years

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis A Multicenter Prospective Randomized Clinical Trial Assessing Implant Design Modifications After 3 Years by : Raes Stefanie

Download or read book A Multicenter Prospective Randomized Clinical Trial Assessing Implant Design Modifications After 3 Years written by Raes Stefanie and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background:The clinical outcome of implant therapy depends, apart from patient-related factors, on implant-related factors such as surface topography, design and prosthetic connection. Although nano-surface modifications increase osseointegration, initial implant stability at time of placement is an important clinical factor in implant survival and is considered a prerequisite for early or immediate loading protocols.Aim:This RCT evaluates the 3 years outcome of modifications of the OsseoSpeed implant (Dentsply Sirona Implants, Mu00f6lndal, Sweden) in terms of survival, bone level and peri-implant health. Alterations in the OsseoSpeed EV consisted of changes in dimensions of body shape, drilling procedures, drill design and abutment connection compared to the original OsseoSpeed TX.Material and methods:120 partially edentulous patients, enrolled in five clinics, were randomized to test (EV) and control (TX). 59 subjects received 79 EV and 61 subjects received 87 TX implants respectively. Cemented permanent restorations were placed on average 9 weeks later on titanium stock abutments. Peri-implant bone level changes, plaque, probing pocket depths and bleeding indices were assessed at restoration placement (baseline), and thereafter at 6, 12 and 36 months.Statistical comparison between EV and TX were done with Mann Whitney U-test with p0.05 as significance level.Results:104 subjects (50 EV, 54 TX) were assessed (66 and 75 implants respectively) after 3 years. Three patients discontinued due to failure, 7dropped out and 6 were not available. The groups were comparable (p0.05) regarding age, gender, race, smoking habits, tooth loss reason, periodontal history, implant location, length and diameter. Mean implant insertion torque was 30u00b113 Ncm and 22u00b19 Ncm for EV and TX, indicating improved stability for the modified protocol. Five of 79 EV implants were lost (93.6%, 4 prior and 1 post-loading). One of 87 TX implants failed prior to loading (98.9%). This difference was not statistically significant. Regarding crestal bone change, a mean gain was observed from baseline to 3 years of 0.29mm (SD 0.72) and 0.21mm (SD 0.48) for EV and TX respectively. Probing pocket depth at 3 years was 2.72mm (SD 0.73) vs. 2.82mm (SD 0.73). Plaque was present on 8.3% and 9.0% of surfaces, and bleeding on probing remained stable with a mean of 17.4% and 18.0%. None of the parameters were statistically significantly different between groups (p>0.05).Conclusion:Peri-implant health did not differ between OsseoSpeed EV and TX implants. A gain in crestal bone levels was observed in both groups but EV implants indicated an improved primary stability.Although not possible to determine, it cannot be excluded that in three of the four early EV failures, a deviation in the cortical bone preparation may have contributed to the outcome.Experiences from this study led to modifications of the suggested drilling protocol including widening of the spongious bone preparation to facilitate the implant placement within recommended torque value.

Small Clinical Trials

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Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

A Prospective Randomized Clinical Trial to Assess the Performance of Microtextured Dental Implants with Or Without a Machined Collar

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Publisher :
ISBN 13 :
Total Pages : 55 pages
Book Rating : 4.:/5 (911 download)

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Book Synopsis A Prospective Randomized Clinical Trial to Assess the Performance of Microtextured Dental Implants with Or Without a Machined Collar by : Elizabeth Felts Randall

Download or read book A Prospective Randomized Clinical Trial to Assess the Performance of Microtextured Dental Implants with Or Without a Machined Collar written by Elizabeth Felts Randall and published by . This book was released on 2015 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aim: To assess the performance of microtextured dental implants with or without a machined collar at one year after placement. Material and Methods: Fifty-eight patients received dental implant therapy to restore missing teeth in one area of the maxilla or mandible at the UAB Department of Graduate Periodontology. Residents in the program placed microtextured implants with a microtextured collar with microgrooves (test group) and microtextured implants with a machined collar (control group). Sites were randomized to the test group or control group. Study visit protocol was followed and implants were restored by off-site dentists. Sixty-nine (69) implants were assessed at one year for a final study visit. The primary outcome was to determine the difference between crestal bone levels in the test versus the control group implants as measured by differences in radiographic crestal bone heights at baseline and one year. Data collected consisted of periapical radiographs and clinical photographs that were taken at specific time points throughout the study period. Statistical analyses using individual t-tests and ANOVA were performed to analyze the data. Results: Statistical analysis determined that a significant difference in marginal bone loss was present between the roughened collar (0.65±0.43) and machined collar (1.20±0.62) MTX implants at one year (p

Oral Implantology

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Publisher : Gordon & Breach Science Publishers
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Oral Implantology by : Shumon Otobe

Download or read book Oral Implantology written by Shumon Otobe and published by Gordon & Breach Science Publishers. This book was released on 1990 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evidence-Based Implant Dentistry

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Publisher : Springer
ISBN 13 : 3319268724
Total Pages : 256 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Evidence-Based Implant Dentistry by : Oreste Iocca

Download or read book Evidence-Based Implant Dentistry written by Oreste Iocca and published by Springer. This book was released on 2016-09-28 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of implant dentistry, presenting up-to-date information that reflects the highest level of scientific evidence as presented in the specialized literature. Among the topics addressed by expert authors are the prognosis of natural tooth versus implant restorations, bone response to implant treatment, placement and loading time, implant design and length, platform design, implant abutments, prosthodontic treatment, reconstructive surgery, and periimplantitis. The amount of data available for the clinician working in the field of implantology is huge and constantly increasing. The task of remaining abreast of the latest evidence and applying it effectively in clinical practice is further hindered by the fact that many scientific papers make contradictory claims and contain methodological flaws and biases that generate confusion and lack of reliability. Against this background, Evidence-Based Implant Dentistry will serve the reader as a dependable and scientifically supported guide to current implant treatment and key issues in the field.

Comprehensive Biomaterials II

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Publisher : Elsevier
ISBN 13 : 0081006926
Total Pages : 4865 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Biomaterials II by : Kevin Healy

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Congenital Craniofacial Deformities: Genetic and Clinical Aspects

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Publisher : Frontiers Media SA
ISBN 13 : 2832537456
Total Pages : 79 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Congenital Craniofacial Deformities: Genetic and Clinical Aspects by : Hanyao Huang

Download or read book Congenital Craniofacial Deformities: Genetic and Clinical Aspects written by Hanyao Huang and published by Frontiers Media SA. This book was released on 2023-10-30 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:

3-year Results from the VA Multicenter Prospective Implant Study

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Publisher :
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.:/5 (63 download)

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Book Synopsis 3-year Results from the VA Multicenter Prospective Implant Study by : Robert J. Genco

Download or read book 3-year Results from the VA Multicenter Prospective Implant Study written by Robert J. Genco and published by . This book was released on 2000 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Atlas of Immediate Dental Implant Loading

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Publisher : Springer Nature
ISBN 13 : 3030055469
Total Pages : 383 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Atlas of Immediate Dental Implant Loading by : Miguel Peñarrocha-Diago

Download or read book Atlas of Immediate Dental Implant Loading written by Miguel Peñarrocha-Diago and published by Springer Nature. This book was released on 2019-10-03 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas, in which a wealth of illustrations are supported by clear explanatory text, offers an up-to-date and comprehensive overview of the immediate restoration of teeth and immediate functional loading when using different implant systems and surfaces in patients with single tooth loss or partial or complete edentulism. It provides guidance on all aspects of technique, including procedures for impression and measurement taking, and describes the surgical and prosthetic protocols applicable in various settings. The coverage encompasses the more advanced techniques used for immediate loading of implants placed in conjunction with grafting/augmentation procedures or in fresh extraction sockets, as well as immediate implant loading for mandibular and maxillary full-arch rehabilitation. This atlas will help dental students and practitioners to gain a sound understanding of immediate loading techniques, including their indications and limitations, and to apply them optimally in their practice. The atlas also shows and explains how to integrate a full digital workflow from the intraoral scanner to solve complex cases in a simple way.

Controversial Topics in Oral and Maxillofacial Surgery, An Issue of Dental Clinics of North America, E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0443183090
Total Pages : 249 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Controversial Topics in Oral and Maxillofacial Surgery, An Issue of Dental Clinics of North America, E-Book by : Harry Dym

Download or read book Controversial Topics in Oral and Maxillofacial Surgery, An Issue of Dental Clinics of North America, E-Book written by Harry Dym and published by Elsevier Health Sciences. This book was released on 2023-11-14 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Dental Clinics, guest editor Dr. Harry Dym brings his considerable expertise to the topic of Controversies in Oral and Maxillofacial Surgery. Evidence-based dentistry based on high-quality research is essential to help develop new treatments and alternative options. This issue tackles clinically relevant controversial subjects and helps present cogent, clear information for the clinician to determine the best possible solution or approach. Contains 14 relevant, practice-oriented topics, including short implants: their role in implant reconstruction; need for cone beam imaging in oral surgery and dentistry?; bisphosphonate therapy and its implications in dentistry and oral surgery; post-procedure analgesic management; controversies in the management of the sleep apnea patient; and more. Provides in-depth clinical reviews on controversies in oral and maxillofacial surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Osseointegration and Dental Implants

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Publisher : John Wiley & Sons
ISBN 13 : 0813804744
Total Pages : 444 pages
Book Rating : 4.8/5 (138 download)

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Book Synopsis Osseointegration and Dental Implants by : Asbjorn Jokstad

Download or read book Osseointegration and Dental Implants written by Asbjorn Jokstad and published by John Wiley & Sons. This book was released on 2009-03-03 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseointegration and Dental Implants offers a comprehensive guide to the state of the art of implant dentistry. Based around the proceedings of the Toronto Osseointegration Conference Revisited, it gathers together information on all aspects of implant dentistry and osseointegration, from basic scientific background, such as the biology of osseointegration and the biomechanics of implant surface design, to clinical relevance, such as treatment planning, loading protocols, and patient rehabilitation. This unique book shows implant dentistry as it is today, in all its diverse clinical applications, and provides an expert discussion of what we know, what we think we know, and what we need to find out.

Contemporary Implant Dentistry

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323043739
Total Pages : 1121 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Contemporary Implant Dentistry by : Carl E. Misch

Download or read book Contemporary Implant Dentistry written by Carl E. Misch and published by Elsevier Health Sciences. This book was released on 2007-11-26 with total page 1121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Turn to this new third edition for consistent outcomes on even your most complex implant cases! World-renowned dental implantologist Carl E. Misch gives you expert advice and guidance on the various surgical approaches to placing implants in the revision of his best-selling classic. Over 1,000 full-color illustrations depict details of implants, related materials, and surgical procedures, while well-known contributors (Mohamed Sharawy, Martha Warren Bidez, Adriano Piatelli, and others) share a wealth of knowledge in their respective fields. This third edition provides an excellent opportunity for you to develop and refine your skills and experience more consistent, predictable clinical outcomes. Thorough explanations of the rationale for implants and their specific characteristics discuss why different options work better for different patients; the rationale behind implant materials and sizes; and the overall science of osteointegrated implants - providing a full understanding of how implants behave under certain circumstances and how to make the best choices for implant patients. Chapter on Diagnostic Imaging and Techniques focuses on the latest technology available to determine patient conditions, familiarizing you with recent advances and how they apply to treatment planning principles. Section on Treatment Planning discusses the rationales for implant placement, variables in implants and patient conditions, and the four degrees of jaw bone density, Dr. Misch's best-known criterion for successful implant placement. Prepares you for actual treatment by reviewing scientific fundamentals such as applied anatomy, biomechanical principles, current biomaterials, prevention and management of dental infections, and pharmacologic considerations. Surgical procedure chapters are of benefit to the implant surgeon and are critical to the restoring dentist who wants to better understand and appreciate surgical concepts. Over 1,000 full-color illustrations depict details of implants, related materials, and surgical procedures. Brand-new coverage includes: Key Implant Positions and Number, Ideal Implant Surgery, Extraction Socket and Barrie Membrane Bone Grafts, Sinus Pathology and Complications of Sinus Grafts, Immediate Loading for a Single Tooth, Partially Edentulous and Completely Edentulous Patient. Important updates include indications and contraindications for rationale of biomechanical treatment plans, layered approach to bone grafting, autograft block bone grafting, soft tissue surgery, and implant esthetics and maintenance. A new chapter on Tissue Engineering uses current information on platelet-rich plasma membranes and other elements of tissue engineering so you can take advantage of appropriate materials. Emphasis on evidence-based implant outcomes provides valuable information on which procedures have the greatest likelihood of success and lowest risk of complications.

Rothman-Simeone The Spine E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323511953
Total Pages : 1956 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Rothman-Simeone The Spine E-Book by : Steven R. Garfin

Download or read book Rothman-Simeone The Spine E-Book written by Steven R. Garfin and published by Elsevier Health Sciences. This book was released on 2017-09-11 with total page 1956 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world’s most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz’s The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today’s newest developments in your practice. Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. Offers a newly revised, streamlined format that makes it easier than ever to find the information you need. Contains new chapters on the clinical relevance of finite element modeling and SI joint surgery. Includes an expanded section on minimally invasive spine surgery, including recent developments and future directions. Provides the latest evidence-based research from high-quality studies, including new randomized controlled trials for lumbar stenosis, surgery, fusion, and injections. Presents the knowledge and expertise of new international contributors, as well as new editorial leadership from Dr. Steven Garfin.

Newman and Carranza's Clinical Periodontology E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 032353323X
Total Pages : 1991 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Newman and Carranza's Clinical Periodontology E-Book by : Michael G. Newman

Download or read book Newman and Carranza's Clinical Periodontology E-Book written by Michael G. Newman and published by Elsevier Health Sciences. This book was released on 2018-05-29 with total page 1991 pages. Available in PDF, EPUB and Kindle. Book excerpt: From basic science and fundamental procedures to the latest advanced techniques in reconstructive, esthetic, and implant therapy, Newman and Carranza's Clinical Periodontology, 13th Edition is the resource you can count on to help master the most current information and techniques in periodontology. Full color photos, illustrations, and radiographs show you how to perform periodontal procedures, while renowned experts from across the globe explain the evidence supporting each treatment and lend their knowledge on how to best manage the outcomes. UNIQUE! Expert Consult platform offers a versatile print and digital resources that help bring text information to life. UNIQUE! Bonus content on Expert Consult includes multiple-choice self-assessment questions with instant feedback, chapter review PowerPoint slides, videos clips, case studies, and more. UNIQUE! Periodontal Pathology Atlas contains the most comprehensive collection of cases found anywhere. Full-color photos and anatomical drawings clearly demonstrate core concepts and reinforce important principles. UNIQUE! Chapter opener boxes in the print book alert readers when more comprehensive coverage of topics is available in the online version of the text. NEW! Chapters updated to meet the current exam requirements for the essentials in periodontal education. NEW! Case-based clinical scenarios incorporated throughout the book mimic the new patient case format used in credentialing exams. NEW! Additional tables, boxes, and graphics highlight need-to-know information. NEW! Virtual microscope on Expert Consult offers easy access to high-resolution views of select pathology images. NEW! Two new chapters cover periimplantitis and resolving inflammation. NEW! Section on evidence-based practice consists of two chapters covering evidence-based decision making and critical thinking.

Lindhe's Clinical Periodontology and Implant Dentistry

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Publisher : John Wiley & Sons
ISBN 13 : 1119438950
Total Pages : 1369 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Lindhe's Clinical Periodontology and Implant Dentistry by : Niklaus P. Lang

Download or read book Lindhe's Clinical Periodontology and Implant Dentistry written by Niklaus P. Lang and published by John Wiley & Sons. This book was released on 2021-07-28 with total page 1369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the latest edition of the cornerstone reference on periodontology and implant dentistry that combines scholarship and science with practical clinical instruction The Seventh Edition of Lindhe's Clinical Periodontology and Implant Dentistry brings together a distinguished team of periodontal specialists and academics who deliver another must-have resource for students, researchers, and practitioners specializing in periodontal care and implant dentistry. Seamlessly integrating the foundational science behind periodontology with practical clinical protocols in two comprehensive volumes, the chapters cover anatomy, microbiology, occlusion trauma, pathology, tissue regeneration, treatment planning protocols, infection control, reconstructive therapy, occlusal and prosthetic therapy, and more. The Seventh Edition of Lindhe's Clinical Periodontology and Implant Dentistry: Provides an introduction to anatomy, including periodontal tissues, the edentulous ridge, the mucosa at teeth and implants, and osseointegration Discusses the epidemiology of periodontal and peri-implant diseases Explores the microbiology, including dental biofilms and calculus, periodontal infections, peri-implant infections, the pathogenesis of gingivitis and periodontitis, and the genetic susceptibility to periodontal disease Includes the latest perio- and peri-implant disease classifications Contains updated evidence-based preventive and treatment modalities for the treatment of periodontal and peri-implant diseases Features the latest evidence-based therapeutic alternatives on the use of dental implants to rehabilitate the lost dentition Perfect for postgraduate dental students, researchers, and practitioners specializing in periodontal care and implant dentistry, Lindhe's Clinical Periodontology and Implant Dentistry continues to be the cornerstone reference work on periodontology.

Implant Surfaces and their Biological and Clinical Impact

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Publisher : Springer
ISBN 13 : 3662453797
Total Pages : 190 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Implant Surfaces and their Biological and Clinical Impact by : Ann Wennerberg

Download or read book Implant Surfaces and their Biological and Clinical Impact written by Ann Wennerberg and published by Springer. This book was released on 2015-01-05 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with the knowledge required in order to understand the chemical, physical, mechanical, and topographical aspects of implant surfaces, as well as their impact on the biological response. Common ways to modify implant surfaces are described, and methods for the evaluation of surface properties are presented in an easy-to-read style. Experimental results that have contributed to surface modifications relevant for commercial available implants are presented, with emphasis on in vivo and clinical studies. While the focus is primarily on surface modifications at the micrometer and nanometer levels, alterations at the millimeter level are also covered, including thread designs and their possible influence on stress distribution. In addition, it is analyzed how surface alterations have changed the clinical long-term results for certain groups of patients.

Translational Surgery

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Publisher : Elsevier
ISBN 13 : 0323906303
Total Pages : 770 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Translational Surgery by :

Download or read book Translational Surgery written by and published by Elsevier. This book was released on 2023-03-22 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it. Focuses on translational research in Surgery, covering the principles of evidence-based medicine and applying those principles to the design of translational investigations Provides a practical, straightforward approach to help surgeons and researchers navigate challenging aspects of study design and implementation Details valuable discussions on the critical appraisal of published studies in Surgery, allowing the reader to effectively use all types of evidence for patient care