A Molecular Genome Scan And Positional Candidate Gene Analysis For Important Economic Traits In The Pig

Download A Molecular Genome Scan And Positional Candidate Gene Analysis For Important Economic Traits In The Pig full books in PDF, epub, and Kindle. Read online A Molecular Genome Scan And Positional Candidate Gene Analysis For Important Economic Traits In The Pig ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

A Molecular Genome Scan and Positional Candidate Gene Analysis for Important Economic Traits in the Pig

Author : Massoud Malek
Publisher :
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.:/5 (143 download)

DOWNLOAD NOW!

Book Synopsis A Molecular Genome Scan and Positional Candidate Gene Analysis for Important Economic Traits in the Pig by : Massoud Malek

Download or read book A Molecular Genome Scan and Positional Candidate Gene Analysis for Important Economic Traits in the Pig written by Massoud Malek and published by . This book was released on 2001 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meat quality contributes considerably to the profit involved in pork production. The main objectives of this study were to identify the chromosomal locations for growth, body composition and meat quality related traits in pigs and to identify genes that control quantitative traits of economic importance. Genome scans were employed to identify these chromosomal regions. A three-generation resource family was developed using two Berkshire grand sires and nine Yorkshire grand dams. Data for 40 traits (growth, body composition and meat quality) were collected from 525 F2 progeny. Linkage analysis and regression interval mapping based on 125 micro satellite markers were used for QTL detection. Significance thresholds were determined by permutation tests. Significant QTL at the chromosome wise 5% level were detected for a total of over 100 growth (chromosomes 1,2,3,4,6, 7, 8, 9, 11, 13, 14, X), back fat (chromosomes 1, 4, 5, 6, 7, 10, 13, 14) and meat quality traits (chromosomes 1, 2, 4, 5, 6, 8, 10, 11, 12, 13, 14, 15, 17, 18, X). Five genes (ACACB, PPP1CC, GPR49, DUSP6, and ATP2B1) from human chromosome 12 were chosen as possible candidate genes for QTL detected on chromosome 5. These genes were successfully mapped by physical and genetic methods. Two genes (DUSP6, ATP2B1) were considered for further positional candidate gene analysis. A ATP2B1-Afl III polymorphism revealed significant associations with growth, body composition, and meat quality traits (glycogen content and potential, and ham and loin pH) in the BxY F2 population, but only with light reflectance of ham in a commercial line. A DUSP6-Pst1 Polymorphism was associated with fat traits, which was consistent in the QTL analysis and association studies in the BxY family and in two commercial lines. The identified ATP2B1 and DUSP6 polymorphisms could potentially be used as markers to track associated QTL and to discover the causative DNA differences.

Molecular Dissection of Genomic Regions Influencing Important Economic Traits in the Pig

Author : Antonio Marcos Costa do Amaral Ramos
Publisher :
ISBN 13 :
Total Pages : 274 pages
Book Rating : 4.:/5 (31 download)

DOWNLOAD NOW!

Book Synopsis Molecular Dissection of Genomic Regions Influencing Important Economic Traits in the Pig by : Antonio Marcos Costa do Amaral Ramos

Download or read book Molecular Dissection of Genomic Regions Influencing Important Economic Traits in the Pig written by Antonio Marcos Costa do Amaral Ramos and published by . This book was released on 2006 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, numerous genes and genomic regions associated with pork quality were identified. There is great potential for the pig industry in using information from molecular markers for the improvement of pork quality traits, such as color, marbling and pH. Besides the traditional fresh pork market, the production of dry-cured pork products, like Country Hams, has also increased. We collected data on fresh and dry-cured Country Hams to investigate the relationships between these traits and to analyze the effect of genetic markers on fresh and dry-cured ham processing characteristics. Significant positive correlations between yield and firmness, color, pH and marbling were detected, indicating that good pork quality is necessary to maximize Country Ham yield. Additionally, a number of genetic markers was significantly associated with yield and fresh pork quality, including the cathepsin F and stearoyl-CoA desaturase genes. Other chromosomal regions affecting pork quality were identified in genome scans, an approach that identified numerous QTL (quantitative trait loci) for pork quality. However, the mutations underlying these QTL need to be identified first in order for the industry to take full advantage of this information. We mapped 21 genetic markers to a QTL region for meat color and lactate related traits located on pig chromosome 17 (SSC17). As a consequence, the marker density of the SSC17 QTL region was greatly improved. This is an important and necessary first step towards the identification of QTL causative mutations. We then dissected the QTL region on SSC17 using a combination of approaches that included novel QTL mapping approaches and the assembly of the largest continuous contig of pig sequence to date. After the regions more likely to contain the QTL causative mutations were identified we individually sequenced 14 genes in these regions and several polymorphisms were discovered, including non-synonymous exonic polymorphisms. Further analyses of the data identified mutations in two genes, AURKA (aurora kinase A) and BMP7 (bone morphogenetic protein 7), that can potentially be responsible for the observed QTL, as well as other markers in linkage disequilibrium with the QTL traits. These results will be helpful for possible pig selection schemes using molecular genetics information.

Molecular and Association Analyses of the Androgen Receptor Gene as a Candidate for Production and Reproduction Traits in Pigs

Author : Nares Trakooljul
Publisher : Cuvillier Verlag
ISBN 13 : 3865373151
Total Pages : 133 pages
Book Rating : 4.8/5 (653 download)

DOWNLOAD NOW!

Book Synopsis Molecular and Association Analyses of the Androgen Receptor Gene as a Candidate for Production and Reproduction Traits in Pigs by : Nares Trakooljul

Download or read book Molecular and Association Analyses of the Androgen Receptor Gene as a Candidate for Production and Reproduction Traits in Pigs written by Nares Trakooljul and published by Cuvillier Verlag. This book was released on 2004 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mapping and Investigational Analysis of Candidate Genes in the Pig

Author : Jill Ann Sherwood
Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.:/5 (744 download)

DOWNLOAD NOW!

Book Synopsis Mapping and Investigational Analysis of Candidate Genes in the Pig by : Jill Ann Sherwood

Download or read book Mapping and Investigational Analysis of Candidate Genes in the Pig written by Jill Ann Sherwood and published by . This book was released on 2001 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of candidate genes in the pig is important for research leading to the improvement of meat quality. In addition, the analysis and characterization has the potential to benefit research in other areas, including human medicine. The diseases of interest for this thesis study included nemaline myopathy and type 2 diabetes mellitus. Identification of candidate genes for these disorders was based on their relationship to certain human diseases, and their potential to affect certain meat quality traits. Four separate genes were chosen based on proposed function in humans, and proposed location based on the human and pig comparative maps: beta tropomyosin (TPM2), muscle glycogen synthase (GYS1), protein-tyrosine phosphatase IB (PTP1B), and cAMP-dependent protein kinase inhibitor gamma (PKIG). The GYS1, PTP1B and PKIG genes may have an effect on diabetes or the development of the disease, and TPM2 may be associated with a phenotype similar to nemaline myopathy. In addition, all of the genes listed have the potential to affect meat quality traits in the pig. For each porcine gene, analysis included partial sequencing, identification of polymorphisms, physical and linkage mapping, and association studies to determine if these genes were associated with any pork quality traits measured. Association studies with GYS1 revealed some association with fat and tenderness-related traits, while analysis of PTP1B showed association with glycogen and lactate-related traits. No significant associations were noted with the TPM2 or PKIG genes in this thesis study. Sequence data for each of these genes adds to the body of knowledge about the pig genome and these specific genes, and identification of the map locations of each of these genes in the pig refines the comparative maps between pigs and humans. In addition, association studies have revealed that two of these genes, GYS1 and PTP1B, may be useful for marker-assisted selection in pigs, and information for all genes has the potential to improve the understanding of human disorders.

Molecular Genetic Analysis of Positional Candidate Genes for Mammary Gland Characteristics in Pigs

Author : Siriwadee Chomdej
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (181 download)

DOWNLOAD NOW!

Book Synopsis Molecular Genetic Analysis of Positional Candidate Genes for Mammary Gland Characteristics in Pigs by : Siriwadee Chomdej

Download or read book Molecular Genetic Analysis of Positional Candidate Genes for Mammary Gland Characteristics in Pigs written by Siriwadee Chomdej and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics of Litter Size and Prenatal Survival in Pigs

Author : Silvia Clara Hernández Velasco
Publisher :
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.:/5 (827 download)

DOWNLOAD NOW!

Book Synopsis Genetics of Litter Size and Prenatal Survival in Pigs by : Silvia Clara Hernández Velasco

Download or read book Genetics of Litter Size and Prenatal Survival in Pigs written by Silvia Clara Hernández Velasco and published by . This book was released on 2012 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Female reproductive performance is a critical component of sustainable pig production systems. There is abundant evidence of genetic variation in these traits among pig breeds. The aims of this study were to identify quantitative trait loci (QTL) affecting reproductive traits and to identify and characterise positional candidate gene(s) underlying the QTL. A Large White - Meishan F2 population was scanned for QTL with effects on reproductive traits. This analysis revealed 13 putative QTLs on seven different chromosomes with effects on five different traits: ovulation rate (OR), teat number (TN), prenatal survival (PS), total born alive (TBA) and litter size (LS). QTL for PS and LS on chromosome 8 were fine mapped and Secreted Phosphoprotein 1 (SPP1) confirmed as a candidate gene. A genome-wide association study was performed on a diverse population of different breeds and crosses lines, for reproductive traits including LS, TBA, number of stillborn piglets, and number of mummified piglets. Fourteen SNPs were found significantly associated with reproductive traits. The functional study of SPP1 examined the hypothesis that differences in foetal growth may be associated with the effectiveness of conceptus attachment, as measured by SPP1 expression. Patterns of SPP1 mRNA and protein expression in placental and uterine tissues supplying the smallest and a normal-sized foetus from the same uterus were examined in Large White-Landrace (LW-LR), Large White (LW) and Meishan (MS) females 40 and 45 of pregnancy. The smallest LW-LR foetuses tended to have a higher level of SPP1 mRNA in endometrium tissue compared to the normal-sized foetuses. However, placenta expression was higher in the normal-sized foetuses compared to the smallest ones. SPP1 protein levels in normal sized foetuses were significantly higher than in the smallest litter mates for all the tissues. Significantly higher levels of SPP1 mRNA and protein were found in MS compared to LW. In both breeds, significant differences between sizes were found in some tissues, with similar expression patterns in respect to size, for both mRNA and protein in endometrial tissues when compared to contemporary LW. In placenta, the direction of the expression differed between breeds, with a higher expression of mRNA and protein in the normal-sized MS foetuses and in the smallest sized LW foetuses. The comparison of SPP1 expression between different foetal sizes and different breeds revealed associations between breed, foetal size, and SPP1 protein, factors implicated in PS and LS. These results together with the genetic evidence indicate that the potential role of SPP1 in placental and foetal development merits further investigation.

The Genetics of the Pig

Author : Max Frederick Rothschild
Publisher : CABI
ISBN 13 : 1845937562
Total Pages : 525 pages
Book Rating : 4.8/5 (459 download)

DOWNLOAD NOW!

Book Synopsis The Genetics of the Pig by : Max Frederick Rothschild

Download or read book The Genetics of the Pig written by Max Frederick Rothschild and published by CABI. This book was released on 2011 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of pig genetics and genomics has advanced significantly in recent years, creating fresh insights into biological processes. This comprehensive reference work discusses pig genetics and its integration with livestock management and production technology to improve performance. Fully updated throughout to reflect advances in the subject, this new edition also includes new information on genetic aspects of domestication, colour variation, genomics and pig breeds, with contributions from international experts active in the field.

Comparative Genome Analysis in the Pig as a Model for Understanding Human Obesity

Author : Kwan-Suk Kim
Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (143 download)

DOWNLOAD NOW!

Book Synopsis Comparative Genome Analysis in the Pig as a Model for Understanding Human Obesity by : Kwan-Suk Kim

Download or read book Comparative Genome Analysis in the Pig as a Model for Understanding Human Obesity written by Kwan-Suk Kim and published by . This book was released on 2003 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation reports on studies of the pig genome as a model to identify obesity-related genes. Pig geneticists have sought to reduce fat in their pigs through selective breeding, and these efforts ultimately improved the genetic potential in the pig for higher growth, increased efficiency of conversion of food into body weight and lower fat percentage in the body. Therefore, the genetic information obtained from lean growth in the pig can be applicable to studying the genetic basis of human obesity and other related health problems. A three-generation pig family and several commercial lines of pigs were used to study porcine obesity quantitative trait loci (QTL), and genes for the relevant phenotypes to human growth and obesity. Several candidate genes were successfully localized within the porcine obesity QTL and the comparative locations of these QTL and candidate genes were discussed in the present study. Furthermore, the relationships between DNA polymorphisms of the candidate genes and a variety of phenotypic measurements were studied. These results provide important insights into the role of biological candidate genes in obesity and other related metabolic disorders. The functional properties of a naturally occurring variant of porcine melanocortin-4 receptor (MC4R) gene were comparatively characterized to determine functionally important structural amino acid residues in the MC4R sequences. This research also discovered a unique imprinting phenotype in the porcine delta-like 1 (DLK1) locus. The imprinting phenotype was first found in the callipyge locus in sheep and called 'polar overdominance'. However, further identification has been elusive in other mammals. The results of the porcine DLK1 locus indicate that the inheritance mechanism of polar overdominance for callipyge sheep might have a conserved role for growth and fat deposition phenotypes in pigs and the DLK1 gene might be an important player for the imprinting phenotypes. This dissertation demonstrates the useful value of comparative genomic study of pigs as a model organism to investigate genes of interest for human health, especially obesity, and the results also have implications for the development of improved genetic selection programs for the targeted traits of interest in pig production systems.

Genetic Analysis of Quantitative Traits Using Domestic Animals

Author : Hee-Bok Park
Publisher :
ISBN 13 : 9789155460563
Total Pages : 51 pages
Book Rating : 4.4/5 (65 download)

DOWNLOAD NOW!

Book Synopsis Genetic Analysis of Quantitative Traits Using Domestic Animals by : Hee-Bok Park

Download or read book Genetic Analysis of Quantitative Traits Using Domestic Animals written by Hee-Bok Park and published by . This book was released on 2004 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt:

High-Throughput Phenotyping in the Genomic Improvement of Livestock

Author : Fabyano Fonseca Silva
Publisher : Frontiers Media SA
ISBN 13 : 2889711455
Total Pages : 216 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis High-Throughput Phenotyping in the Genomic Improvement of Livestock by : Fabyano Fonseca Silva

Download or read book High-Throughput Phenotyping in the Genomic Improvement of Livestock written by Fabyano Fonseca Silva and published by Frontiers Media SA. This book was released on 2021-08-03 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Genomics

Author : Bhanu P. Chowdhary
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!

Book Synopsis Animal Genomics by : Bhanu P. Chowdhary

Download or read book Animal Genomics written by Bhanu P. Chowdhary and published by S. Karger AG (Switzerland). This book was released on 2003 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals, and the initiation of whole genome sequencing projects for some of the animal species. Like in humans and mice, this will set the stage for a new level of research and real time complex analysis of the genomes of these species. Animal Genomics signifies the beginning of a new era in this field and celebrates the achievements of the past 20 years of genomics research. It will be of special interest to researchers involved in genome analysis - both gross chromosomal as well as molecular - in various animal species, and to comparative and evolutionary geneticists.

Proceedings

Author :
Publisher :
ISBN 13 :
Total Pages : 474 pages
Book Rating : 4.E/5 ( download)

DOWNLOAD NOW!

Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on 1998 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: New technologies for the production of "Next Generation" feeds and additives; Food safety in veterinary science; Recent advances in animal genome and genetic resources for efficient animal production; Role of water buffaloes in producing foods; Efficient animal producion systems in harsh environments.

A Bird's-Eye View of Veterinary Medicine

Author : Carlos C. Perez-Marin
Publisher : BoD – Books on Demand
ISBN 13 : 9535100319
Total Pages : 630 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!

Book Synopsis A Bird's-Eye View of Veterinary Medicine by : Carlos C. Perez-Marin

Download or read book A Bird's-Eye View of Veterinary Medicine written by Carlos C. Perez-Marin and published by BoD – Books on Demand. This book was released on 2012-02-22 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary medicine is advancing at a very rapid pace, particularly given the breadth of the discipline. This book examines new developments covering a wide range of issues from health and welfare in livestock, pets, and wild animals to public health supervision and biomedical research. As well as containing reviews offering fresh insight into specific issues, this book includes a selection of scientific articles which help to chart the advance of this science. The book is divided into several sections. The opening chapters cover the veterinary profession and veterinary science in general, while later chapters look at specific aspects of applied veterinary medicine in pets and in livestock. Finally, research papers are grouped by specialisms with a view to exploring progress in areas such as organ transplantation, therapeutic use of natural substances, and the use of new diagnostic techniques for disease control. This book was produced during World Veterinary Year 2011, which marked the 250th anniversary of the veterinary profession. It provides a fittingly concise and enjoyable overview of the whole science of veterinary medicine.

European Local Pig Breeds - Diversity and Performance

Author : Marjeta Čandek-Potokar
Publisher : BoD – Books on Demand
ISBN 13 : 1789854075
Total Pages : 320 pages
Book Rating : 4.7/5 (898 download)

DOWNLOAD NOW!

Book Synopsis European Local Pig Breeds - Diversity and Performance by : Marjeta Čandek-Potokar

Download or read book European Local Pig Breeds - Diversity and Performance written by Marjeta Čandek-Potokar and published by BoD – Books on Demand. This book was released on 2019-02-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Local or autochthonous pig breeds represent a pool of genetic diversity of porcine species and a link with old-style traditional production systems and traditional pork products. These breeds were largely abandoned because they were not competitive in the concept of modern, industrial type of pig production. Despite an increased interest for local pig breeds in the past years, they remain largely untapped and the knowledge about their characteristics is limited, which was a challenge undertook in the project TREASURE in the frame of multicriteria evaluation of local pig breeds. The book represents a valuable compendium of data on census, breeding organisations, production systems, and performances with ambition to present their contemporary (preserved) phenotype. This work has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634476 for project with acronym TREASURE. The content of this book reflects only the authors' view and the European Union Agency is not responsible for any use that may be made of the information it contains.

Dissertation Abstracts International

Author :
Publisher :
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!

Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2006 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Commencement

Author : Iowa State University
Publisher :
ISBN 13 :
Total Pages : 562 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!

Book Synopsis Commencement by : Iowa State University

Download or read book Commencement written by Iowa State University and published by . This book was released on 2001 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proceedings of the 9th International Congress on Obesity

Author : Geraldo Medeiros-Neto
Publisher : John Libbey Eurotext
ISBN 13 : 9782742004607
Total Pages : 1084 pages
Book Rating : 4.0/5 (46 download)

DOWNLOAD NOW!

Book Synopsis Proceedings of the 9th International Congress on Obesity by : Geraldo Medeiros-Neto

Download or read book Proceedings of the 9th International Congress on Obesity written by Geraldo Medeiros-Neto and published by John Libbey Eurotext. This book was released on 2003 with total page 1084 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is officially recognised as a major worldwide public health problem. "Progress in Obesity Research: 9" fulfils the need for an accessible and fundamental research, highly recommended towards a better understanding of obesity. It will prove an indispensable resource for all those involved in the research, prevention and treatment of obesity.