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Author : Zheng Fu
Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.3/5 (121 download)
Download or read book A Combinatorial Approach to Genome-wide Ortholog Assignment Via Genome Rearrangement written by Zheng Fu and published by . This book was released on 2007 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Guanqun Shi
Publisher :
ISBN 13 : 9781124940571
Total Pages : 75 pages
Book Rating : 4.9/5 (45 download)
Download or read book Combinatorial Approaches to Accurate Identification of Orthologous Genes written by Guanqun Shi and published by . This book was released on 2011 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: The accurate identification of orthologous genes across different species is a critical and challenging problem in comparative genomics and has a wide spectrum of biological applications including gene function inference, evolutionary studies and systems biology. During the past several years, many methods have been proposed for ortholog assignment based on sequence similarity, phylogenetic approaches, synteny information, and genome rearrangement. Although these methods share many commonly assigned orthologs, each method tends to produce an ortholog assignment significantly different from the others.
Author : Josep Diaz
Publisher : Springer
ISBN 13 : 3540380450
Total Pages : 532 pages
Book Rating : 4.5/5 (43 download)
Download or read book Approximation, Randomization, and Combinatorial Optimization. Algorithms and Techniques written by Josep Diaz and published by Springer. This book was released on 2006-08-29 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the joint refereed proceedings of the 9th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX 2006 and the 10th International Workshop on Randomization and Computation, RANDOM 2006. The book presents 44 carefully reviewed and revised full papers. Among the topics covered are design and analysis of approximation algorithms, hardness of approximation problems, small spaces and data streaming algorithms, embeddings and metric space methods, and more.
Author : Peter Markstein
Publisher : World Scientific
ISBN 13 : 1908979097
Total Pages : 472 pages
Book Rating : 4.9/5 (89 download)
Download or read book Computational Systems Bioinformatics (Volume 6) - Proceedings Of The Conference Csb 2007 written by Peter Markstein and published by World Scientific. This book was released on 2007-09-12 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. Abstracts from the keynote addresses and invited talks are also included.The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field./a
Author : Peter Markstein
Publisher : World Scientific
ISBN 13 : 1860948731
Total Pages : 472 pages
Book Rating : 4.8/5 (69 download)
Download or read book Computational Systems Bioinformatics written by Peter Markstein and published by World Scientific. This book was released on 2007 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. Abstracts from the keynote addresses and invited talks are also included. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Sample Chapter(s). Chapter 1: Whole-Genome Analysis of Dorsal Gradient Thresholds in the Drosophila Embryo (102 KB). Contents: Learning Predictive Models of Gene Regulation (C Leslie); Algorithms for Selecting Breakpoint Locations to Optimize Diversity in Protein Engineering by Site-Directed Protein Recombination (W Zheng et al.); Cancer Molecular Pattern Discovery by Subspace Consensus Kernel Classification (X Han); Transcriptional Profiling of Definitive Endoderm Derived from Human Embryonic Stem Cells (H Liu et al.); A Markov Model Based Analysis of Stochastic Biochemical Systems (P Ghosh et al.); Clustering of Main Orthologs for Multiple Genomes (Z Fu & T Jiang); Extraction, Quantification and Visualization of Protein Pockets (X Zhang & C Bajaj); Consensus Contact Prediction by Linear Programming (X Gao et al.); An Active Visual Search Interface for Medline (W Xuan et al.); Exact and Heuristic Algorithms for Weighted Cluster Editing (S Rahmann et al.); Reconcilation with Non-binary Species Trees (B Vernot et al.); and other papers. Readership: Research and application community in bioinformatics, systems biology, medicine, pharmacology and biotechnology. Graduate researchers in bioinformatics and computational biology.
Author : Guillaume Bourque
Publisher : Springer Science & Business Media
ISBN 13 : 3540445293
Total Pages : 239 pages
Book Rating : 4.5/5 (44 download)
Download or read book Comparative Genomics written by Guillaume Bourque and published by Springer Science & Business Media. This book was released on 2006-09-19 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 4th RECOMB Comparative Genomics Satellite Workshop, RECOMB-CG 2006. The 17 revised full papers presented were carefully reviewed and selected from 34 initial submissions. The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from new quantitative discoveries about genome structure and process to theorems on the complexity of computational problems inspired by genome comparison.
Author : Hervé Tettelin
Publisher : Springer Nature
ISBN 13 : 3030382818
Total Pages : 311 pages
Book Rating : 4.0/5 (33 download)
Download or read book The Pangenome written by Hervé Tettelin and published by Springer Nature. This book was released on 2020-04-30 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Author : Olivier Gascuel
Publisher : OUP Oxford
ISBN 13 : 9780191513732
Total Pages : 444 pages
Book Rating : 4.5/5 (137 download)
Download or read book Mathematics of Evolution and Phylogeny written by Olivier Gascuel and published by OUP Oxford. This book was released on 2005-02-24 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book considers evolution at different scales: sequences, genes, gene families, organelles, genomes and species. The focus is on the mathematical and computational tools and concepts, which form an essential basis of evolutionary studies, indicate their limitations, and give them orientation. Recent years have witnessed rapid progress in the mathematics of evolution and phylogeny, with models and methods becoming more realistic, powerful, and complex. Aimed at graduates and researchers in phylogenetics, mathematicians, computer scientists and biologists, and including chapters by leading scientists: A. Bergeron, D. Bertrand, D. Bryant, R. Desper, O. Elemento, N. El-Mabrouk, N. Galtier, O. Gascuel, M. Hendy, S. Holmes, K. Huber, A. Meade, J. Mixtacki, B. Moret, E. Mossel, V. Moulton, M. Pagel, M.-A. Poursat, D. Sankoff, M. Steel, J. Stoye, J. Tang, L.-S. Wang, T. Warnow, Z. Yang, this book of contributed chapters explains the basis and covers the recent results in this highly topical area.
Author : Guillaume Fertin
Publisher : MIT Press
ISBN 13 : 0262062828
Total Pages : 305 pages
Book Rating : 4.2/5 (62 download)
Download or read book Combinatorics of Genome Rearrangements written by Guillaume Fertin and published by MIT Press. This book was released on 2009 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.
Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128170778
Total Pages : 476 pages
Book Rating : 4.1/5 (281 download)
Download or read book Pan-genomics: Applications, Challenges, and Future Prospects written by Debmalya Barh and published by Academic Press. This book was released on 2020-03-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics, thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics , encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives Discusses current bioinformatics tools and strategies for exploiting pangenomics data Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Author : Stephen J. O'Brien
Publisher : John Wiley & Sons
ISBN 13 : 1119418046
Total Pages : 1008 pages
Book Rating : 4.1/5 (194 download)
Download or read book Atlas of Mammalian Chromosomes written by Stephen J. O'Brien and published by John Wiley & Sons. This book was released on 2020-04-02 with total page 1008 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE UPDATED NEW EDITION OF THE POPULAR COLLECTION OF HIGH-RESOLUTION CHROMOSOME PHOTOGRAPHS—FOR GENETICISTS, MAMMOLOGISTS, AND BIOLOGISTS INTERESTED IN COMPARATIVE GENOMICS, SYSTEMATICS, AND CHROMOSOME STRUCTURE Filled with a visually exquisite collection of the banded metaphase chromosome karyotypes from some 1,000 species of mammals, the Atlas of Mammalian Chromosomes offers an unabridged compendium of the state of this genomic art form. The Atlas??contains the best karyotype produced, the common and Latin name of the species, the published citation, and identifies the contributing authors. Nearly all karyotypes are G-banded, revealing the chromosomal bar codes of homologous segments among related species. The Atlas brings together information from a range of cytogenetic literature and features high-quality karyotype images for nearly every mammal studied to date. When the Atlas was first published, only three mammals were sequenced. Today, that number is over 300. Now in its second edition, this book contains extensive revisions and major additions such as new karyotypes that employ G- and C- banding to represent euchromatin and heterochromatin genome composition, new phylogenetic trees for each order, homology segment chromosome information on published aligned chromosome painting. Summaries of the painting data for some species indicate conserved homology segments among compared species. An invaluable resource for today's comparative genomics era, this comprehensive collection of high-resolution chromosome photographs: Assembles information previously scattered throughout the cytogenetics literature in one comprehensive volume Provides chromosome information and illustrations for the karyotypes of 300 new species Addresses the mandate of the Human Genome Project to annotate the genomes of other organisms Serves as a basis for chromosome-level genome assemblies Offers a detailed summation of three decades of ZooFish (chromosome painting) Presents high-resolution photos of karyotypes that represent more than 1,000 mammal species Written for geneticists, mammalogists, and biologists, the Atlas of Mammalian Chromosomes offers a step forward for an understanding of species formation, of genome organization, and of DNA script for natural selection.
Author :
Publisher :
ISBN 13 :
Total Pages : 888 pages
Book Rating : 4.3/5 (91 download)
Download or read book Mathematical Reviews written by and published by . This book was released on 2008 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marie-Paule Lefranc
Publisher : Elsevier
ISBN 13 : 0080542646
Total Pages : 413 pages
Book Rating : 4.0/5 (85 download)
Download or read book The T Cell Receptor FactsBook written by Marie-Paule Lefranc and published by Elsevier. This book was released on 2001-07-13 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.
Author : João Carlos Setubal
Publisher : Springer Nature
ISBN 13 : 1071638386
Total Pages : 622 pages
Book Rating : 4.0/5 (716 download)
Download or read book Comparative Genomics written by João Carlos Setubal and published by Springer Nature. This book was released on with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Renato Paro
Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)
Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Author : Vishvanath Nene
Publisher : Springer Science & Business Media
ISBN 13 : 3540740422
Total Pages : 253 pages
Book Rating : 4.5/5 (47 download)
Download or read book Genome Mapping and Genomics in Animal-Associated Microbes written by Vishvanath Nene and published by Springer Science & Business Media. This book was released on 2008-11-24 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achievements and progress in genome mapping and the genomics of microbes supersede by far those for higher plants and animals, in part due to their enormous economic implication but also smaller genome size. In the post-genomic era, whole genome sequences of animal-associated microbes are providing clues to depicting the genetic basis of the complex host-pathogen relationships and the evolution of parasitism; and to improving methods of controlling pathogens. This volume focuses on a globally important group of intracellular prokaryotic pathogens which affect livestock animals. These include Brucella, Mycobacterium, Anaplasma and Ehrlichia, as well as the protozoan pathogens Cryptosporidium and Theileria, for which genome sequence data is available. Insights from comparative genomics of the microbes described provide clues to the adaptation involved in host-microbe interactions, as well as resources potentially useful for application in future research and product development.
Author : Supratim Choudhuri
Publisher : Elsevier
ISBN 13 : 0124105106
Total Pages : 238 pages
Book Rating : 4.1/5 (241 download)
Download or read book Bioinformatics for Beginners written by Supratim Choudhuri and published by Elsevier. This book was released on 2014-05-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration
