Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download A Characterization Of Pyrin full books in PDF, epub, and Kindle. Read online A Characterization Of Pyrin ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Philip E. Schaner
Publisher :
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.3/5 (91 download)
Download or read book A Characterization of Pyrin written by Philip E. Schaner and published by . This book was released on 2003 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Pablo Pelegrin
Publisher : Academic Press
ISBN 13 : 0323972063
Total Pages : 674 pages
Book Rating : 4.3/5 (239 download)
Download or read book Inflammasome Biology written by Pablo Pelegrin and published by Academic Press. This book was released on 2022-11-23 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities is a complete reference on the role of inflammasomes in health and disease. Sections cover the different types of inflammasomes, including cellular signaling, structural and evolutive aspects, overview the role of inflammasomes in key diseases, microbial infections and human body systems conditions, cover the interplay between Inflammasomes and cell death processes, and discuss current therapeutic opportunities driven by inflammasome research, including targeting, blocking and inhibiting the development of inflammasomes through both synthetic and natural compounds. This book is the perfect reference for cell biologists, immunologists and research clinicians to understand the foundations of inflammasomes and explore the therapeutic opportunities they present. Pharma researchers may also find this reference invaluable in devising new approaches to developing anti-inflammatory drugs. - Provides comprehensive coverage of the subject of inflammasome biology - Authored by leading experts worldwide - Provides biological insights that have both health implications and therapeutic potential
Author : Tommy Hlaing
Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.3/5 (91 download)
Download or read book Molecular Characterization of Defcap written by Tommy Hlaing and published by . This book was released on 2002 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 810 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2009 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dirk Holzinger
Publisher : Frontiers Media SA
ISBN 13 : 2889716619
Total Pages : 119 pages
Book Rating : 4.8/5 (897 download)
Download or read book Management of Autoinflammatory Diseases in Childhood written by Dirk Holzinger and published by Frontiers Media SA. This book was released on 2021-11-24 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 708 pages
Book Rating : 4.:/5 (31 download)
Download or read book The Journal of Immunology written by and published by . This book was released on 2007 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1681088304
Total Pages : 229 pages
Book Rating : 4.6/5 (81 download)
Download or read book Frontiers in Anti-Infective Drug Discovery: Volume 9 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-05-24 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs
Author : Edward D. Zanders
Publisher : John Wiley & Sons
ISBN 13 : 1118849825
Total Pages : 454 pages
Book Rating : 4.1/5 (188 download)
Download or read book Human Drug Targets written by Edward D. Zanders and published by John Wiley & Sons. This book was released on 2015-12-14 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of drug targets in a given disease has been central to pharmaceutical research from the latter half of the 20th century right up to the modern genomics era. Human Drug Targets provides an essential guide to one of the most important aspects of drug discovery – the identification of suitable protein and RNA targets prior to the creation of drug development candidates. The first part of the book consists of introductory chapters that provide the background to drug target discovery and highlight the way in which these targets have been organised into online databases. It also includes a user’s guide to the list of entries that forms the bulk of the book. Since this is not designed to be a compendium of drugs, the emphasis will be on the known (or speculated) biological role of the targets and not on the issues associated with pharmaceutical development. The objective is to provide just enough information to be informative and prompt further searches, while keeping the amount of text for each of the many entries to a minimum. Human Drug Targets will prove invaluable to those drug discovery professionals, in both industry and academia, who need to make some sense of the bewildering array of online information sources on current and potential human drug targets. As well as creating order out of a complex target landscape, the book will act as an ideas generator for potentially novel targets that might form the basis of future discovery projects.
Author : Charles W. Carter
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121827779
Total Pages : 756 pages
Book Rating : 4.8/5 (277 download)
Download or read book Macromolecular Crystallography written by Charles W. Carter and published by Gulf Professional Publishing. This book was released on 1997 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Phases * Map interpretation and refinement * Analysis and software.
Author : Lia Rimondini
Publisher : Frontiers Media SA
ISBN 13 : 2889666875
Total Pages : 176 pages
Book Rating : 4.8/5 (896 download)
Download or read book Rational Design and Characterization of Innovative Multifunctional Biomimetic Materials written by Lia Rimondini and published by Frontiers Media SA. This book was released on 2021-04-13 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Christine M. De Nardo
Publisher : Humana
ISBN 13 : 9781627035224
Total Pages : 0 pages
Book Rating : 4.0/5 (352 download)
Download or read book The Inflammasome written by Christine M. De Nardo and published by Humana. This book was released on 2013-07-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.
Author : Susan L. Fink
Publisher : Springer Nature
ISBN 13 : 1071630407
Total Pages : 228 pages
Book Rating : 4.0/5 (716 download)
Download or read book Pyroptosis written by Susan L. Fink and published by Springer Nature. This book was released on 2023-04-19 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores techniques used to study and understand the latest research on pyroptosis. The chapters in this book cover topics such as experimental methods to induce pyroptosis via inflammasomes; approaches to identifying inflammasome activation in humans; ways to induce and detect pore formation; and techniques to evaluate cellular outcomes of pyroptotic cell death. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Pyroptosis: Methods and Protocols is a valuable tool for researchers who want to expand their knowledge of this developing field. It will be especially beneficial for those working in the fields of immunology, cancer biology, microbiology, and cell biology.
Author : Marco Gattorno
Publisher : Springer
ISBN 13 : 3319146157
Total Pages : 166 pages
Book Rating : 4.3/5 (191 download)
Download or read book Familial Mediterranean Fever written by Marco Gattorno and published by Springer. This book was released on 2015-03-19 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic autoinflammatory disease. The opening chapters explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies. A large part of the book is then devoted to a detailed description of the typical and atypical clinical presentations, the disease course, and potential complications in both pediatric and adult patients. Guidance is provided on the measurement of disease severity and the management of patients in daily practice. The advice regarding treatment is based on the best currently available evidence and attention is also paid to important emerging treatments. The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Monogenic autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Familial Mediterranean fever itself is due to a mutation in the MEFV gene, which codes for the protein pyrin; it is characterized by periodic fever and episodes of painful inflammation in the abdomen, chest, and joints. Familial Mediterranean Fever will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with the disease.
Author : Anthony A. Gaspari
Publisher : Springer
ISBN 13 : 3319297856
Total Pages : 889 pages
Book Rating : 4.3/5 (192 download)
Download or read book Clinical and Basic Immunodermatology written by Anthony A. Gaspari and published by Springer. This book was released on 2017-04-24 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated volume provides a “user-friendly” reference for dermatologists, dermatology residents and students, as well as for health care workers in related fields to better understand immune-mediated skin diseases and their therapies. The focus is on what is needed by the physician/resident or student for betting understanding the pathophysiology of the disease as well as the mechanisms of action of the therapies. The reader can easily read about groups of related diseases as well as groups of related therapies. The level of complexity of the book is such that it has practical applications on a daily basis but can also be used by the resident as a teaching tool and as a handy source of review for the boards. In addition, it can be used the practicing dermatologist to study for recertification. The scope of the book is immunology, immunogenetics, immunopathology and immunopharmacology as they relate to clinical dermatology.
Author : Tom O'Brien
Publisher : CRC Press
ISBN 13 : 9781420045413
Total Pages : 312 pages
Book Rating : 4.0/5 (454 download)
Download or read book Design of Caspase Inhibitors as Potential Clinical Agents written by Tom O'Brien and published by CRC Press. This book was released on 2008-10-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the Therapeutic Potential for Caspase Inhibitors: Present and Future Caspases represent one of the most specific protease families described to date. These extremely important enzymes are crucial to the destruction of aberrant cells – the body’s self-protection mechanism for warding off the growth of abnormal cells, many of which can promote cancer. Design of Caspase Inhibitors as Potential Clinical Agents introduces cutting-edge evidence regarding caspases’ role in pro-inflammatory responses. New research now shows that the inhibition of caspase function is a critical component for the treatment of many diseases, including: Arthritic and neurological disorders Lung disease Hereditary fever syndromes Inflammatory bowel and skin diseases Sepsis Liver fibrosis Outlines Efforts to Develop Molecule Inhibitors for Caspase Activity Transformation Under the editorial guidance of authoritative inflammatory disease, small molecule discovery, and apoptosis researchers, the book organizes the wide array of caspase literature into one convenient resource. It also summarizes the relative difficulty of transitioning a caspase small molecule inhibitor from the lab to the clinic and suggests approaches to circumvent this difficulty. Taking a novel, yet core approach to disease treatment, this seminal work sets the stage to combat a slew of debilitating diseases through groundbreaking drug development.
Author : Heide Schatten
Publisher : Springer
ISBN 13 : 1493929046
Total Pages : 395 pages
Book Rating : 4.4/5 (939 download)
Download or read book The Cytoskeleton in Health and Disease written by Heide Schatten and published by Springer. This book was released on 2015-08-21 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.
Author : K. Aktories
Publisher : Springer Science & Business Media
ISBN 13 : 3662059711
Total Pages : 713 pages
Book Rating : 4.6/5 (62 download)
Download or read book Bacterial Protein Toxins written by K. Aktories and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
