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2007 Archaea
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Download or read book Archaea written by Roger A. Garrett and published by John Wiley & Sons. This book was released on 2008-05-12 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduced by Crafoord Prize winner Carl Woese, this volumecombines reviews of the major developments in archaeal researchover the past 10–15 years with more specialized articlesdealing with important recent breakthroughs. Drawing on majorthemes presented at the June 2005 meeting held in Munich to honorthe archaea pioneers Wolfram Zillig and Karl O. Stetter, the bookprovides a thorough survey of the field from its controversialbeginnings to its ongoing expansion to include aspects ofeukaryotic biology. The editors have assembled articles from the premier researchersin this rapidly burgeoning field, including an account by CarlWoese of his original discovery of the Archaea (until 1990 termedarchaebacteria) and the initially mixed reactions of the scientificcommunity. The review chapters and specialized articles address theemerging significance of the Archaea within a broader scientificand technological context, and include accounts of cutting-edgeresearch developments. The book spans archaeal evolution,physiology, and molecular and cellular biology and will be anessential reference for both graduate students and researchers.
Book Synopsis Biocommunication of Archaea by : Guenther Witzany
Download or read book Biocommunication of Archaea written by Guenther Witzany and published by Springer. This book was released on 2017-09-27 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Archaea represent a third domain of life with unique properties not found in the other domains. Archaea actively compete for environmental resources. They perceive themselves and can distinguish between ‘self’ and ‘non-self’. They process and evaluate available information and then modify their behaviour accordingly. They assess their surroundings, estimate how much energy they need for particular goals, and then realize the optimum variant. These highly diverse competences show us that this is possible owing to sign(aling)- mediated communication processes within archaeal cells (intra-organismic), between the same, related and different archaeal species (interorganismic), and between archaea and nonarchaeal organisms (transorganismic). This is crucial in coordinating growth and development, shape and dynamics. Such communication must function both on the local level and between widely separated colony parts. This allows archaea to coordinate appropriate response behaviors in a differentiated manner to their current developmental status and physiological influences. This book will orientate further investigations on how archaeal ecosphere inhabitants communicate with each other to coordinate their behavioral patterns and whats the role of viruses in this highly dynamic interactional networks.
Download or read book 2007 Archaea written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Archaea are a fascinating and diverse group of prokaryotic organisms with deep roots overlapping those of eukaryotes. The focus of this GRC conference, 'Archaea: Ecology Metabolism & Molecular Biology', expands on a number of emerging topics highlighting the evolution and composition of microbial communities and novel archaeal species, their impact on the environment, archaeal metabolism, and research that stems from sequence analysis of archaeal genomes. The strength of this conference lies in its ability to couple reputable areas with new scientific topics in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.
Book Synopsis Recent advances in genomic and genetic studies in the Archaea by : Frank T. Robb
Download or read book Recent advances in genomic and genetic studies in the Archaea written by Frank T. Robb and published by Frontiers E-books. This book was released on with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: The accumulation of archaeal genomes has lagged significantly behind the Bacteria; however, in the last several years the coverage of the major phyla of Archaea has been significantly improved. There are now multiple genomes in several important genera such as Pyrobaculum, Sulfolobus, Thermococcus/Pyrococcus, Halobacterium, Methanosarcina, Methanopyrus and Methanocaldococcus. Comparative genomic studies are now under way, and in many cases there are several consortial multilaboratory groups, such as the SulfoSys community, which have started to break into new systems biology initiatives. At the same time, access to streamlined genetic approaches in the genera Sulfolobus, Thermococcus, Methanosarcina, and Halobacterium/Haloferax has improved significantly and is leveraging the genomic information in the Archaea. The result has been that genome-driven studies of metabolism, DNA replication and repair, transcription and translation, and posttranslational processing have become more detailed and that basic research findings are burgeoning. The areas of global gene regulation, the roles of small RNAs and mechanisms of transcription and DNA replication will be focus areas in the guidelines of this Research Topic. Recently, insights into the unique characteristics of archaeal transcription and the ability to study the effects of mutation in vivo following knock-in gene replacement have resulted in incisive findings.
Book Synopsis Brenner's Encyclopedia of Genetics by : Stanley Maloy
Download or read book Brenner's Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics
Book Synopsis Computational Methods for Understanding Bacterial and Archaeal Genomes by : Ying Xu
Download or read book Computational Methods for Understanding Bacterial and Archaeal Genomes written by Ying Xu and published by World Scientific. This book was released on 2008 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.
Book Synopsis Proceedings of the International Workshop on Geo-Omics of Archaea by : Chuanlun Zhang
Download or read book Proceedings of the International Workshop on Geo-Omics of Archaea written by Chuanlun Zhang and published by Frontiers Media SA. This book was released on 2022-02-16 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis RNA Metabolism and Gene Expression in Archaea by : Béatrice Clouet-d'Orval
Download or read book RNA Metabolism and Gene Expression in Archaea written by Béatrice Clouet-d'Orval and published by Springer. This book was released on 2017-10-28 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.
Book Synopsis Archaeal Cell Envelope and Surface Structures by : Sonja-Verena Albers
Download or read book Archaeal Cell Envelope and Surface Structures written by Sonja-Verena Albers and published by Frontiers Media SA. This book was released on 2016-03-10 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Archaea and Bacteria have complex cell envelopes that play important roles in several vital cellular processes, including serving as a barrier that protects the cytoplasm from the environment. Along with associated proteinaceous structures, cell envelopes also ensure cell stability, promote motility, mediate adherence to biotic and abiotic surfaces, and facilitate communication with the extracellular environment. While some aspects of the biosynthesis and structure of the cell are similar to the three domains of life, archaeal cell envelopes exhibit several unique characteristics. Moreover, recent analyzes have revealed that many features of cell envelopes can vary greatly between distantly related archaea. The collection of reviews and original research papers in this focused issue describes research that has been significantly expanded in our understanding of the mechanisms underlying the biogenesis and functions of archaeal cell envelopes and their constituent surface structures. Jain et al. (5) cytoplasmic membrane, isoprenoid lipid bilayer, as well as recently revealed the cytoplasmic membrane biosynthesis, which is conserved across the three domains of life. Complementing this review, Andreas Klingl summarizes the diverse structures and functions of archaeal cytoplasmic membranes (8). While most archaeal cells have a single membrane, the archaea have an outer membrane, which has been thought of in a different variety of archaeal lineages. One particular intriguing diderm is the hyperthermophilic archaeon. In the periplasmic space, ATP in the periplasmic space. Complementing this work, Kletzin provides an in-depth review of evolutionarily conserved and unique archaeal inner and outer membrane-associated cytochromes (7). The periplasmic space between the membranes of archaeal diderms does not contain a peptidoclycan layer. In fact, while the cytoplasmic membrane is superimposed by an S-layer in many monoderm archaea, it is unclear how diderms, and even some monoderm extremophiles that varnish to S-layer, withstand osmotic stress. As noted by Klingl (8), glycocalyx, lipoglycans, or other protective cell-associated glycoproteins, may take on the functions of a cell wall in some archaea. One such secreted protein, as described by Zenke et al., Is the halomucin of Haloquadratum walsbyi (15). While H. walsbyi does not have a cell wall, halomucine, an unusually large protein (9159aa), is thought to play an important role in protecting these extreme halophiles against desiccation. Interestingly, Candidatus Altiarchaeum hamiconexum, an uncultured diderm euryarchaeon, isolated from biofilms containing hammers, cell surface proteins with the appearance of grappling hooks that connect cells to each other and to abiotic surfaces. Perra's stunning imagery suggests that this is the case with the S-layer glycoproteins, possibly suggesting a case of divergent evolution (12). [0003] The present invention relates to a method and apparatus for the preparation of a medical device, Are conserved across the prokaryotic domains, being found in the majority of sequenced archaea, where, as in bacteria, they play key roles in processes necessary for biofilm formation (10, 13). Interestingly, as discussed by Albers and Jarrell (1), as well as Näther et al. (11), a type IV pilus-like structure is responsible for swimming motility in archaea. Many secreted proteins, including the S-layer glycoprotein and pilin-like proteins, are heavily post-translationally modified. [1]. [0002] The known proteolytic modifications of the proteins of the model haloarchaeon [1], vol. Using the results of proteomic studies, Leon et al. (9), providing an invaluable resource in silico prediction tools for the characterization of archaeal proteins, in general, but also specific phyla. Kandiba and Eichler review our current knowledge of N-glycosylation in archaea, including descriptions of the pathways the regulatory roles of this post-translational modification plays in cellular processes (6). Considering the unique aspects of the archaeal cell envelope, including not only the protein structures, but their post-translational modifications as well, it is not surprising that archaeal viruses have evolved specific mechanisms to infect and egress from archaeal cells, which are reviewed in this Issue by Quemin and Quax (14). Understanding the roles that can be seen in this book is a study of the development of biofuels in the field of bioinformatics, including mucosa-associated methanogenic archaea, can (2). (2) In this paper, Archaeal cell membranes and S-layer glycoproteins have been used to make liposomes and nanomaterials. Finally, a better understanding of the similarities and differences among the archaea as well as between the archaea and the other two domains will lead to the development of a more accurate phylogeny. In this issue, Forterre takes advantage of the latest profusion of genome studies, along with supporting in vivo work, to assemble an improved tree of life (3). Conflict of Interest Statement The authors declare that this is not the case. Acknowledgments The support of the National Science Foundation MCB-1413158 to MP and the ERC starting grant 311523 (archaellum) to SA are gratefully acknowledged. References: 1. Albers SV & Jarrell KF (2015) The archaellum: how Archaea swim. Frontiers in microbiology 6:23. 2. Bang C, et al. (2014) Biofilm formation of mucosa-associated methanoarchaeal strains. Frontiers in microbiology 5: 353. 3. Forterre P (2015) The Universal Tree: an update. Frontiers in Microbiology, in 4. Gimenez MI, Cerletti M, & De Castro RE (2015) Archaeal membrane-associated proteases: insights on Haloferax volcanii and other haloarchaea. Frontiers in microbiology 6:39. 5. Jain S, Caforio A, & Driessen AJ (2014) Biosynthesis of archaeal membrane ether lipids. Frontiers in microbiology 5: 641. 6. Kandiba L & Eichler J (2014) Archaeal S-layer glycoproteins: post-translational modification in the face of extremes. Frontiers in microbiology 5: 661. 7. Kletzin A, et al. (2015) Cytochromes c in Archaea: distribution, maturation, cell architecture, and the special case of Ignicoccus hospitalis. Frontiers in microbiology 6: 439. 8. Klingl A (2014) S-layer and cytoplasmic membrane - exceptions from the typical archaeal cell wall with a focus on double membranes. Frontiers in microbiology 5: 624. 9. Leon DR, et al. (2015) Mining proteomic data to expose protein modifications to methanosarcina mazei strain Go1. Frontiers in microbiology 6: 149. 10. Losensky G, Vidakovic L, Klingl A, Pfeifer F, & Frols S (2014) Novel pili-like surface structures of Halobacterium salinarum strain R1 are crucial for surface adhesion. Frontiers in microbiology 5: 755. 11. Nather-Schindler DJ, Schopf S, Bellack A, Rachel R, & Wirth R (2014) Pyrococcus furiosus flagella: biochemical and transcriptional analyzes identify the newly detected flaB0 gene to encode the major flagellin. Frontiers in microbiology 5: 695. 12. Perras AK, et al. (2015) S-layers at second glance? Altiarchaeal grappling hooks (hami) resemble archaeal S-layer proteins in structure and sequence. Frontiers in microbiology 6: 543. 13. Pohlschroder M & Esquivel RN (2015) Archaeal type IV pili and their involvement in biofilm formation. Frontiers in microbiology 6:19. 14. Quemin ER & Quax TE (2015) Archaeal viruses at the cell envelope: entry and egress. Frontiers in microbiology 6: 552. 15. Zenke R, et al. (2015) fluorescence microscopy visualization of halomucin, a secreted 927 kDa protein surrounding haloquadratum walsbyi cells. Frontiers in microbiology 6: 249.
Book Synopsis Archaea in the Environment: Views on Archaeal Distribution, Activity, and Biogeography by : Andreas Teske
Download or read book Archaea in the Environment: Views on Archaeal Distribution, Activity, and Biogeography written by Andreas Teske and published by Frontiers Media SA. This book was released on 2021-05-03 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Origin of Life via Archaea by : Richard Gordon
Download or read book Origin of Life via Archaea written by Richard Gordon and published by John Wiley & Sons. This book was released on 2024-08-26 with total page 1190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys the models for the origin of life and presents a new model starting with shaped droplets and ending with life as polygonal Archaea; it collects the most published micrographs of Archaea (discovered only in 1977), which support this conclusion, and thus provides the first visual survey of Archaea. Origin of Life via Archaea’s purpose is to add a new hypothesis on what are called “shaped droplets”, as the starting point, for flat, polygonal Archaea, supporting the Vesicles First hypothesis. The book contains over 6000 distinct references and micrographs of 440 extant species of Archaea, 41% of which exhibit polygonal phenotypes. It surveys the intellectual battleground of the many ideas of the origin of life on earth, chemical equilibrium, autocatalysis, and biotic polymers. This book contains 17 chapters, some coauthored, on a wide range of topics on the origin of life, including Archaea’s origin, patterns, and species. It shows how various aspects of the origin of life may have occurred at chemical equilibrium, not requiring an energy source, contrary to the general assumption. For the reader’s value, its compendium of Archaea micrographs might also serve many other interesting questions about Archaea. One chapter presents a theory for the shape of flat, polygonal Archaea in terms of the energetics at the surface, edges and corners of the S-layer. Another shows how membrane peptides may have originated. The book also includes a large table of most extant Archaea, that is searchable in the electronic version. It ends with a chapter on problems needing further research. Audience This book will be used by astrobiologists, origin of life biologists, physicists of small systems, geologists, biochemists, theoretical and vesicle chemists.
Book Synopsis RNA Turnover in Bacteria, Archaea and Organelles by : Lynne E. Maquat
Download or read book RNA Turnover in Bacteria, Archaea and Organelles written by Lynne E. Maquat and published by Academic Press. This book was released on 2008-12-23 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. Covers the difference in processing of mRNA between eukaryotes, bacteria and archea. Benefit: Processing of mRNA differs greatly between eukaryotes, bacteria and archea and this affords researchers readily reproducible techniques to understand and study the molecular pathogenesis of disease Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover which are central to the process of gene expression. Benefit: Keeps MIE buyers and online subscribers up-to-date with the latest research Offers step by step lab instructions including necessary equipment and reagents. Benefit: Provides tried and tested techniques which eliminate searching through many different sources. Tested techniques are trustworthy and avoid pitfalls so the same mistakes are not made over and over
Book Synopsis The Marine Microbiome by : Lucas J. Stal
Download or read book The Marine Microbiome written by Lucas J. Stal and published by Springer Nature. This book was released on 2022-02-28 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and expanded second edition reviews numerous aspects of the marine microbiome and its possible industrial applications. The marine microbiome is the total of microorganisms and viruses in the ocean and seas and in any connected environment, including the seafloor and marine animals and plants. In the first part of the book, diversity, origin and evolution of the marine microorganisms and viruses are discussed. The microbes presented originate from all three domains of life: Bacteria, Archaea, and Eukarya. The second part sheds some light on the different communities: it describes marine habitats and how their inhabitants control biogeochemical cycles. The third part finally examines the microbial ocean as a global system and evaluates methods of utilizing marine microbial resources. Adopting a translational approach, the book connects academic research with industrial applications, making it a fascinating read and valuable resource for microbiologists from both domains.
Book Synopsis Handbook of Molecular Microbial Ecology II by : Frans J. de Bruijn
Download or read book Handbook of Molecular Microbial Ecology II written by Frans J. de Bruijn and published by John Wiley & Sons. This book was released on 2011-09-27 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the first comprehensive two-volume reference to cover unculturable microorganisms in a large variety of habitats, which could not previously have been analyzed without metagenomic methodology. It features review articles as well as a large number of case studies, based largely on original publications and written by international experts. This second volume, Metagenomics in Different Habitats, covers such topics as: Viral genomes Metagenomics studies in a variety of habitats, including marine environments and lakes, soil, and human and animal digestive tracts Other habitats, including those involving microbiome diversity in human saliva and functional intestinal metagenomics; diversity of archaea in terrestrial hot springs; and microbial communities living at the surface of building stones Biodegradation Biocatalysts and natural products A special feature of this book is the highlighting of the databases and computer programs used in each study; they are listed along with their sites in order to facilitate the computer-assisted analysis of the vast amount of data generated by metagenomic studies. Such studies in a variety of habitats are described here, which present a large number of different system-dependent approaches in greatly differing habitats. Handbook of Molecular Microbial Ecology II is an invaluable reference for researchers in metagenomics, microbial ecology, microbiology, and environmental microbiology; those working on the Human Microbiome Project; microbial geneticists; and professionals in molecular microbiology and bioinformatics.
Download or read book Nitrification written by Bess B. Ward and published by American Society for Microbiology Press. This book was released on 2011-03-25 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: A full review of the latest research findings on microbes involved in conventional aerobic nitrification, anaerobic ammonia oxidation, and related processes. • Examines the four principal groups of nitrifying microbes including conventional aerobic bacterial ammonia oxidizers, recently discovered aerobic archaeal ammonia oxidizers, anaerobic ammonia-oxidizing planctomycetes, and nitrite-oxidizing bacteria. • Provides current information on the ecology, phylogeny, biochemistry, molecular biology, and genomics of each group of microbes. • Discusses the latest industrial applications of nitrification and anammox processes, and explores the ecology of nitrification in marine, freshwater, soil, and wastewater environments.
Book Synopsis The Biology of Reproduction by : Giuseppe Fusco
Download or read book The Biology of Reproduction written by Giuseppe Fusco and published by Cambridge University Press. This book was released on 2019-10-10 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: A look into the phenomena of sex and reproduction in all organisms, taking an innovative, unified and comprehensive approach.
Book Synopsis Evolutionary Genomics and Systems Biology by : Gustavo Caetano-Anoll¿s
Download or read book Evolutionary Genomics and Systems Biology written by Gustavo Caetano-Anoll¿s and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.
