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Author : Stephen J. Pandol
Publisher : Frontiers Media SA
ISBN 13 : 288963082X
Total Pages : 191 pages
Book Rating : 4.8/5 (896 download)
Download or read book Xenobiotics and the Gut Microbiome in Health and Disease written by Stephen J. Pandol and published by Frontiers Media SA. This book was released on 2019-10-14 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309458390
Total Pages : 133 pages
Book Rating : 4.3/5 (94 download)
Download or read book The Chemistry of Microbiomes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-19 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
Author :
Publisher : Elsevier
ISBN 13 : 0323997872
Total Pages : 290 pages
Book Rating : 4.3/5 (239 download)
Download or read book Human Microbiome in Health and Disease - Part A written by and published by Elsevier. This book was released on 2022-09-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Microbiome in Health and Disease, Volume 191, Part A presents updated knowledge on human microbiome as covered by renowned science faculty across the globe. Chapters in this volume include an introduction to human microbiome, Structure, functions and diversity of healthy human microbiome, Role of human microbiome in cancer, Gut microbiota and gastrointestinal cancer, Dysbiosis of human microbiome and metabolic diseases, Gut microbiome and type 2 diabetes, Gut microbiome and non-alcoholic fatty liver disease, Hepatic drug metabolism and intestinal microbiota, Emerging tools for understanding the human microbiome, and Microbiome therapeutics: Opportunity and challenges, and more. These chapters cover the composition, diversity, dynamics and functions of human microbiome in health and disease. This book will form an excellent and informative text on keystone, autochthonous, and exogenous microbiota important for human health in a simple to understand and easy to read format. Covers the structure, functions and diversity of human microbiome in health and disease Includes discussions on drug metabolisms and microbiome based therapeutics Presents emerging tools for understanding the human microbiome
Author : Alessio Fasano
Publisher : MIT Press
ISBN 13 : 0262362694
Total Pages : 551 pages
Book Rating : 4.2/5 (623 download)
Download or read book Gut Feelings written by Alessio Fasano and published by MIT Press. This book was released on 2021-03-16 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why the microbiome—our rich inner ecosystem of microorganisms—may hold the keys to human health and change the way we understand, treat, and prevent disease. We are at the dawn of a new scientific revolution. Our understanding of how to treat and prevent diseases has been transformed by knowledge of the microbiome—the rich ecosystem of microorganisms in and on every human. In Gut Feelings, Alessio Fasano and Susie Flaherty show why we must go beyond the older, myopic view of microorganisms as our enemies to a broader understanding of the microbiome as a parallel civilization that we need to understand, respect, and engage with for the benefit of our own health. Recent advances in understanding the microbiome and its role in human health dovetail with the development of personalized or “precision” medicine to create treatments and prevention programs targeted to the molecular imprint of an individual. Fasano and Flaherty explore the microbiome's part in such diseases as gut inflammatory disorders, obesity, neurological conditions, and cancer, and they explain new research in prebiotics, probiotics, synbiotics, and psychobiotics. They also discuss the microbiome and immune function, including a possible role in COVID-19 treatment. By simultaneously expanding our perspective to encompass large datasets and multiple factors in human health, and narrowing our focus to identify the individual communities in the human microbiome, we will enlarge—and perhaps reinvent—our understanding of how to combat disease and maintain health.
Author : Nathan W. Schmidt
Publisher : Frontiers Media SA
ISBN 13 : 288963003X
Total Pages : 275 pages
Book Rating : 4.8/5 (896 download)
Download or read book The Gut Microbiome in Health and Disease written by Nathan W. Schmidt and published by Frontiers Media SA. This book was released on 2019-12-24 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Debabrata Biswas
Publisher : Springer Nature
ISBN 13 : 3030473848
Total Pages : 288 pages
Book Rating : 4.0/5 (34 download)
Download or read book Gut Microbiome and Its Impact on Health and Diseases written by Debabrata Biswas and published by Springer Nature. This book was released on 2020-08-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.
Author : Dirk Haller
Publisher : Springer
ISBN 13 : 3319905457
Total Pages : 356 pages
Book Rating : 4.3/5 (199 download)
Download or read book The Gut Microbiome in Health and Disease written by Dirk Haller and published by Springer. This book was released on 2018-07-27 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Author : Hans Selye
Publisher : Springer Science & Business Media
ISBN 13 : 3642651925
Total Pages : 1158 pages
Book Rating : 4.6/5 (426 download)
Download or read book Hormones and Resistance written by Hans Selye and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 1158 pages. Available in PDF, EPUB and Kindle. Book excerpt: 7 If so, the individual members of each class thus identified could then be subjected to a more profound pharmacokinetic analysis. In other words, we had to determine first which hormone protects against which drug, before we could explore how it did this. We had to know first that a hormone has adaptive value before we could ask whether this is due to a syntoxic or a catatoxic mechanism. Such observations, as the fact that an indomethacin-induced intestinal ulcer can be prevented by ethylestrenol, orthat cortisol aggravates certain infections, reveal nothing about how these hormones work; but only findings of this type can tell us where further research would be rewarding. Of course, scientists can rarely identify by direct observation the tbings that they are looking for; most of the time they have to be guided by indirect indices. The ebernist often first detects a compound, or even a particular functional group in its molecule, by inference from a color reaction, a revealing X-ray diffraction pattern or the formation of a characteristic precipitate. The physician must first suspect the presence of a microbe through certain clinical signs and symptoms before he can verify his diagnosis by looking for a particular organism. It is perhaps not too daring to hope that in our first efforts to clarify the role of hormones in resistance, simple, directly visible indicators might also serve us best.
Author : Shayne Cox Gad
Publisher : CRC Press
ISBN 13 : 042978144X
Total Pages : 477 pages
Book Rating : 4.4/5 (297 download)
Download or read book Toxicology of the Gastrointestinal Tract, Second Edition written by Shayne Cox Gad and published by CRC Press. This book was released on 2018-10-26 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309468698
Total Pages : 123 pages
Book Rating : 4.3/5 (94 download)
Download or read book Environmental Chemicals, the Human Microbiome, and Health Risk written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-01 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.
Author : Ana R. Maria Moise
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.4/5 (6 download)
Download or read book The Gut Microbiome written by Ana R. Maria Moise and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This accessibly written, comprehensive summary of research findings on the gut microbiome and its implications for health and disease--a topic of growing interest and concern--serves as an essential resource for teachers and students. Most people know that the digestive tract contains billions of helpful gut bacteria, but how does the gut microbiome affect our health? What exactly do these bacteria do, and what are the negative effects when these microorganisms are harmed by what we eat and do? What impacts might they have on conditions such as irritable bowel syndrome (IBS), obesity, and autism? This book provides an accessible, holistic introduction to the study of the human gut microbiome and its effects on digestion and disease--one of the newest and most rapidly expanding fields in medicine today. The gut microbiome is known as "the forgotten organ" because it is not identified as part of the human body per se, yet it has an immense influence on many systems in the body. The Gut Microbiome: Exploring the Connection between Microbes, Diet, and Health explains what the microbiome is, the many functions it serves, how it can be either harmed or supported by our actions, and the role it may play in various diseases and in determining our overall health. The book examines the various potential causes of imbalance in the microbiome, such as diet and other lifestyle factors, and then identifies strategies for improving human health by protecting the gut microbiota. The science-based information is detailed but accessible to general readers or students without extensive background knowledge.
Author : Gilberto Antonio Bastidas Pacheco
Publisher : BoD – Books on Demand
ISBN 13 : 1789859018
Total Pages : 376 pages
Book Rating : 4.7/5 (898 download)
Download or read book Parasitology and Microbiology Research written by Gilberto Antonio Bastidas Pacheco and published by BoD – Books on Demand. This book was released on 2020-06-17 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of both unicellular and multicellular living beings and the diseases they produce from a biological point of view requires constant review of their relationship with their host and environment, given their indisputable sanitary importance. In this sense, in parasitology and microbiology, updated and concise information on life cycle, taxonomic classification, clinical manifestations, diagnosis, treatment, epidemiological behavior, and control measures is of vital importance. This is what we pursue with this book. The approach to parasitology and microbiology and the research that is carried out on it is unquestionable because the associations between life forms have been present from the very beginning of life.Research in parasitology and microbiology is necessary and indispensable for controlling diseases that affect much of the world with serious economic and social consequences. The challenge is to promote research to keep these diseases at bay. This book shows what has been done up to now and what can be done in the future to combat infectious diseases.
Author : C.S.M. Cowan
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331806856X
Total Pages : 158 pages
Book Rating : 4.3/5 (18 download)
Download or read book Microbes and the Mind written by C.S.M. Cowan and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-06 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.
Author : George Jabboure Netto
Publisher : Springer
ISBN 13 : 3319968300
Total Pages : 638 pages
Book Rating : 4.3/5 (199 download)
Download or read book Genomic Applications in Pathology written by George Jabboure Netto and published by Springer. This book was released on 2018-12-10 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the applications and demands continue to evolve rapidly. This has created a tremendous need for a comprehensive resource on genomic applications in clinical and anatomic pathology. We believe that our current textbook provides such a resource to practicing molecular pathologists, hematopathologists and other subspecialized pathologists, general pathologists, pathology and other trainees, oncologists, geneticists and a growing spectrum of other clinicians. With periodic updates and a sufficiently rapid time from submission to publication, this textbook will be the resource of choice for many professionals and teaching programs. Its focus on genomics parallels the evolution of these technologies as primary methods in the clinical lab. The rapid evolution of genomics and its applications in medicine necessitates the (frequent) updating of this publication. This text will provide a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays will be discussed together with issues related to reporting and the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms will be detailed. Genomic applications in pharmacogenomics, inherited genetic diseases and infectious diseases will also be discussed. The latest iteration of practice recommendations or guidelines in genomic testing put forth by stakeholder professional organizations such as the College of American Pathology and the Association for Molecular Pathology, will be discussed as well as regulatory issues and laboratory accreditation related to genomic testing. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.
Author : Akhileshwar Kumar Srivastava
Publisher : Academic Press
ISBN 13 : 0323906818
Total Pages : 328 pages
Book Rating : 4.3/5 (239 download)
Download or read book Xenobiotics in Chemical Carcinogenesis written by Akhileshwar Kumar Srivastava and published by Academic Press. This book was released on 2022-02-17 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development. Lastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants. Covers the exposure and transmission of various toxic xenobiotics substances, including nanomaterials, to humans and their interaction with specific tissues in precipitating the development of cancers Unravels the toxicokinetic and toxicodynamic processes of toxic xenobiotics in bioaccumulation Examines the genetic aberrations in cancer genomes by genetic-environmental interactions in carcinogenesis Explains the biotransformation mechanisms of toxic xenobiotics by gut microbes in humans
Author : Francisco A . Tomás-Barberán
Publisher : John Wiley & Sons
ISBN 13 : 1119563720
Total Pages : 560 pages
Book Rating : 4.1/5 (195 download)
Download or read book Dietary Polyphenols written by Francisco A . Tomás-Barberán and published by John Wiley & Sons. This book was released on 2020-12-15 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.
Author : B. Koletzko
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318026913
Total Pages : 334 pages
Book Rating : 4.3/5 (18 download)
Download or read book Pediatric Nutrition in Practice written by B. Koletzko and published by Karger Medical and Scientific Publishers. This book was released on 2015-04-17 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no other time in life when the provision of adequate and balanced nutrition is of greater importance than during infancy and childhood. During this dynamic phase characterized by rapid growth, development and developmental plasticity, a sufficient amount and appropriate composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and the metabolic programming of long-term health and well-being. This compact reference text provides concise information to readers who seek quick guidance on practical issues in the nutrition of infants, children and adolescents. After the success of the first edition, which sold more than 50'000 copies in several languages, the editors prepared this thoroughly revised and updated second edition which focuses again on nutritional challenges in both affluent and poor populations around the world. Serving as a practical reference guide, this book will contribute to further improving the quality of feeding of healthy infants and children, as well as enhancing the standards of nutritional care in sick children.
