Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Xenobiotics And Cancer
Download Xenobiotics And Cancer full books in PDF, epub, and Kindle. Read online Xenobiotics And Cancer ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author :Takamatsu no Miya Hi Gan Kenkyū Kikin. International Symposium Publisher :Taylor & Francis ISBN 13 :9780748400379 Total Pages :394 pages Book Rating :4.4/5 (3 download)
Book Synopsis Xenobiotics and Cancer by : Takamatsu no Miya Hi Gan Kenkyū Kikin. International Symposium
Download or read book Xenobiotics and Cancer written by Takamatsu no Miya Hi Gan Kenkyū Kikin. International Symposium and published by Taylor & Francis. This book was released on 1991 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 21st International Symposium of the Princess Takamatsu Cancer Resarch Fund covered advances in chemical carcinogenesis and cancer chemotherapy. It notes that humans are continuously exposed to carcinogens, so the amount of carcinogenic xenobiotics and the human response to them is important.
Book Synopsis Xenobiotics in Chemical Carcinogenesis by : Akhileshwar Kumar Srivastava
Download or read book Xenobiotics in Chemical Carcinogenesis written by Akhileshwar Kumar Srivastava and published by Academic Press. This book was released on 2022-02-17 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development. Lastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants. Covers the exposure and transmission of various toxic xenobiotics substances, including nanomaterials, to humans and their interaction with specific tissues in precipitating the development of cancers Unravels the toxicokinetic and toxicodynamic processes of toxic xenobiotics in bioaccumulation Examines the genetic aberrations in cancer genomes by genetic-environmental interactions in carcinogenesis Explains the biotransformation mechanisms of toxic xenobiotics by gut microbes in humans
Author :Takamatsu no Miya Hi Gan Kenkyū Kikin. International Symposium Publisher : ISBN 13 :9784762246678 Total Pages :368 pages Book Rating :4.2/5 (466 download)
Book Synopsis Xenobiotics and Cancer; Implications for Chemical Carcinogenesis and Cancer Chemotherapy by : Takamatsu no Miya Hi Gan Kenkyū Kikin. International Symposium
Download or read book Xenobiotics and Cancer; Implications for Chemical Carcinogenesis and Cancer Chemotherapy written by Takamatsu no Miya Hi Gan Kenkyū Kikin. International Symposium and published by . This book was released on 1991 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Encyclopedia of Cancer by : Manfred Schwab
Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Book Synopsis XENOBIOTIC METABOLIZING GENE POLYMORPHISMS AND SUSCEPTIBILITY TO HEAD AND NECK CANCER by : Dr.A. Anuradha
Download or read book XENOBIOTIC METABOLIZING GENE POLYMORPHISMS AND SUSCEPTIBILITY TO HEAD AND NECK CANCER written by Dr.A. Anuradha and published by Lulu.com. This book was released on 2017-12-30 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a term used to describe diseases in which abnormal cells divide without control and are able to invade different tissues. Cancer cells can spread to various parts of the body through the blood and lymph systems. There are more than 100 different kinds of cancers. Cancers are often named for the organ or type of cell in which they start - for example, colon cancer means cancer in the colon. Different Cancers can be grouped into broader categories.
Book Synopsis The Potential Role of Xenobiotics in the Etiology of Breast Cancer by : Diane Cheryl Carter
Download or read book The Potential Role of Xenobiotics in the Etiology of Breast Cancer written by Diane Cheryl Carter and published by . This book was released on 1995 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Xenobiotic Metabolism by : John W. Finley
Download or read book Xenobiotic Metabolism written by John W. Finley and published by . This book was released on 1985 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolism of Drugs and Other Xenobiotics by : Pavel Anzenbacher
Download or read book Metabolism of Drugs and Other Xenobiotics written by Pavel Anzenbacher and published by John Wiley & Sons. This book was released on 2012-02-23 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Genetic Polymorphisms in Xenobiotic Metabolism Enzyme Genes and Their Associations with Colorectal Cancer and Breast Cancer in Han Chinese Population by : Linghong Liao
Download or read book Genetic Polymorphisms in Xenobiotic Metabolism Enzyme Genes and Their Associations with Colorectal Cancer and Breast Cancer in Han Chinese Population written by Linghong Liao and published by . This book was released on 2008 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :International Society for the Study of Xenobiotics Publisher :Taylor & Francis Group ISBN 13 : Total Pages :400 pages Book Rating :4.3/5 (91 download)
Book Synopsis Metabolism of Xenobiotics by : International Society for the Study of Xenobiotics
Download or read book Metabolism of Xenobiotics written by International Society for the Study of Xenobiotics and published by Taylor & Francis Group. This book was released on 1988 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Bhaskar L. V. K. S. Publisher :Createspace Independent Publishing Platform ISBN 13 :9781534786523 Total Pages :64 pages Book Rating :4.7/5 (865 download)
Book Synopsis Detox Genes by : Bhaskar L. V. K. S.
Download or read book Detox Genes written by Bhaskar L. V. K. S. and published by Createspace Independent Publishing Platform. This book was released on 2016-06-20 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotransformation is the metabolic conversion of endogenous and xenobiotic chemicals to more water-soluble compounds. Xenobiotic biotransformation is accomplished by a limited number of enzymes with broad substrate specificities. Liver is considered to be the main center of detoxification. The result of biotransformation in most cases is detoxification; nevertheless, metabolism of some xenobiotics produces metabolites more reactive than their substrate compound and leads to harmful changes. The biotransformation system involves several enzyme systems that are commonly divided into two phases. Phase I enzymes are responsible for oxidation, reduction or hydrolysis and can be either detoxifying or activating. Phase II enzymes exert mainly detoxifying potential by conjugation. The cytochrome P450 enzyme superfamily, including CYP1A1 and CYP2E1 constitutes the majority of Phase I enzymes, while the microsomal epoxide hydrolase (mEH), N-acetyl transferases (NATs) and Glutathione S-Transferases are phase II enzymes primarily responsible for detoxification of xenobiotics. Accumulating data suggest that genetic polymorphisms in genes controlling carcinogen metabolism is responsible for the individual variations in cancer risk. From the broad literature available, the current book project summarizes the role specific polymorphisms in genes encoding xenobiotic metabolism, in predisposing the individuals to various cancers.
Book Synopsis Cytochromes P450 by : Costas Ioannides
Download or read book Cytochromes P450 written by Costas Ioannides and published by Royal Society of Chemistry. This book was released on 2008 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by a team of internationally respected scientists, this book provides up-to-date information on the extensively studied cytochrome P450 enzyme in a very accessible manner.
Book Synopsis Bioactive Compounds and Cancer by : John A. Milner
Download or read book Bioactive Compounds and Cancer written by John A. Milner and published by Humana. This book was released on 2016-08-23 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the wealth of new information generated by the scientific community during the last decade on the role of nutrition on cancer risk, this book provides a forum for presentation and discussion of recent scientific data and highlights a set of dietary recommendations. Bioactive Compounds and Cancer presents chapters that highlight laboratory and clinical findings on how selected nutrients function as signaling molecules and, as such, influence cellular behavior and cancer predisposition. This important compendium focuses on understanding the role of nutrition in cancer biology, the molecular action of bioactive food components and xenobiotics on cancer risk, the role of dietary components in cancer prevention and/or treatment, and nutrition education with the most up to date dietary recommendations that may reduce cancer risk. This volume will be of interest to specialized health professionals, clinicians, nurses, basic and clinical researchers, graduate students, and health officials of public and private organizations.
Book Synopsis Toward Absolute Quantitation in Cell Culture by : Claire Marie Doskey
Download or read book Toward Absolute Quantitation in Cell Culture written by Claire Marie Doskey and published by . This book was released on 2016 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic health science research, which includes cell culture, typically underpins clinical and toxicological research. The results are used to predict biological effects of xenobiotics, e.g. environmental toxins and drugs, in humans. A goal of this research program was to apply aspects of quantitative redox biology to three separate, but interrelated projects that address improvements that can be made to evidence-based biological and toxicological research. This includes using absolute quantitation: to improve the specification of dose of xenobiotics added to cell culture systems; to determine absolute differences between the antioxidant capacity of tumor and normal cells; and to predict the implications of this new knowledge on the use of pharmacological ascorbate as an adjuvant in cancer therapy. Dose is a central parameter in determining the biological consequences of a xenobiotic; however, the dose of a xenobiotic at which these consequences are observed is dependent not only on biological variables, but also the physical aspects of cell culture experiments (i.e. cell number, medium volume). This is often overlooked due to the unrecognized ambiguity in the dominant metric used to express dose, i.e. initial concentration of xenobiotic. We hypothesized that specifying the dose of xenobiotics absolutely (as moles of xenobiotic per cell; mol cell-1) will reduce this ambiguity and provide additional information that is difficult to discern when traditional dosing metrics (initial concentration) are used. We investigated the use of mol cell-1 as an informative dosing metric using two model compounds: 1,4-benzoquinone and oligomycin A. When the dose of these two compounds was specified as mole cell-1, the toxicity observed was independent of the physical conditions used (i.e. number of cells, volume of medium).
Book Synopsis Xenobiotic Modulation of Human Mammary Epithelial Cell Gap Junctional Intercellular Communication and Growth by :
Download or read book Xenobiotic Modulation of Human Mammary Epithelial Cell Gap Junctional Intercellular Communication and Growth written by and published by . This book was released on 1997 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of breast cancer is increasing dramatically in the United States. Man-made environmental agents such as pesticides, polychlorinated biphenyls (PCBs), phthalate esters, and dioxin have been implicated in this increase. Many xenobiotics such as DDT and PCBs have weak estrogenic activity and may enhance breast cancer formation by an estrogenic effect on breast epithelial cell growth. These agents also inhibit gap junctional intercellular communication (GJIC). This effect may be involved in the ability of these agents to enhance growth and breast cancer formation. The studies outlined in this proposal will determine whether there is a link between xenobiotic inhibition of human mammary epithelial cell GJIC, growth, and estrogenicity. These studies are highly relevant to the prevention of breast cancer. An understanding of the relationship between xenobiotic inhibition of GJIC, estrogenic activity, and the enhancement of growth in human breast epithelial cells will lead to more widely acceptable, mechanism-based arguments that xenobiotics are involved in the etiology of human breast cancer. This should lead to more focused regulatory efforts to reduce exposure to these agents.
Book Synopsis Genetic Polymorphisms of the Human Xenobiotic-metabolising Enzymes by : Zhao Bin
Download or read book Genetic Polymorphisms of the Human Xenobiotic-metabolising Enzymes written by Zhao Bin and published by . This book was released on 1998 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
