Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download X Ray Crystallographic Studies Of Three Nucleic Acid Binding Proteins full books in PDF, epub, and Kindle. Read online X Ray Crystallographic Studies Of Three Nucleic Acid Binding Proteins ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : Bart L. Staker
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)
Download or read book X-ray Crystallographic Studies of Three Nucleic Acid Binding Proteins written by Bart L. Staker and published by . This book was released on 2000 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eric Ennifar
Publisher : Humana
ISBN 13 : 9781493946419
Total Pages : 0 pages
Book Rating : 4.9/5 (464 download)
Download or read book Nucleic Acid Crystallography written by Eric Ennifar and published by Humana. This book was released on 2016-10-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes comprehensive and up-to-date coverage of all nucleic-acid-specific steps used in X-ray crystallography, from macromolecule production to structure determination. Chapters dedicated to RNA preparation and crystallogenesis will be of interest to beginners, while chapters focused on data collection, phasing and refinement will be particularly useful to researchers with a higher level of expertise. Several functional case studies are also presented in the last part of the book. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Nucleic Acid Crystallography: Methods and Protocols presents protocols that are aimed at both researchers and students who are interested in the structural biology of DNA or RNA, alone or in complex with proteins or ligands.
Author : Arnaud Ducruix
Publisher :
ISBN 13 : 0199636788
Total Pages : 460 pages
Book Rating : 4.1/5 (996 download)
Download or read book Crystallization of Nucleic Acids and Proteins written by Arnaud Ducruix and published by . This book was released on 1999 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crystallography is the major method of determining structures of biological macromolecules yet crystallization techniques are still regarded as difficult to perform. This new edition of Crystallization of Nucleic Acids and Proteins: A Practical Approach continues in the vein of the first edition by providing a detailed and rational guide to producing crystals of proteins and nucleic acids of sufficient quantity and quality for diffraction studies. It has been thoroughly updated to include all the major new techniques such as the uses of molecular biology in structural biology (maximizing expression systems, sequence modifications to enable crystallization, and the introduction of anomalous scatterers); diagnostic analysis of prenucleation and nucleation by spectroscopic methods; and the two- dimensional electron crystallography of soluble proteins on planar lipid films. As well as an introduction to crystallogenesis, the other topics covered are: Handling macromolecular solutions, experimental design, seeding, proceeding from solutions to crystals Crystallization in gels Crystallization of nucleic acid complexes and membrane proteins Soaking techniques Preliminary characterization of crystals in order to tell whether they are suitable for diffraction studies. As with all Practical Approach books the protocols have been written by experienced researchers and are tried an tested methods. The underlying theory is brought together with the laboratory protocols to provide researchers with the conceptual and methodological tools necessary to exploit these powerful techniques. Crystallization of Nucleic Acids and Proteins: A Practical Approach 2e will be an invaluable manual of practical crystallization methods to researchers in molecular biology, crystallography, protein engineering, and biological chemistry.
Author : Stephen Neidle
Publisher : Springer
ISBN 13 : 1349063789
Total Pages : 236 pages
Book Rating : 4.3/5 (49 download)
Download or read book Topics in Nucleic Acid Structure written by Stephen Neidle and published by Springer. This book was released on 1987-06-18 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chenda O. Seng
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (871 download)
Download or read book Studies on the Three-dimensional Structures of Proteins Using X-ray Crystallography written by Chenda O. Seng and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: X-ray diffraction is the technique of choice to determine the three-dimensional structures of proteins. In this study it has been applied to solve the structure of the survival motor neuron (SMN) proteins, the Fenna-Mathews-Olson (FMO) from Pelodictyon phaeum (Pld. phaeum) protein, and the synthetic ATP binding protein DX. Spinal muscular atrophy (SMA) is an autosomal recessive genetic disease resulting in muscle atrophy and paralysis via degeneration of motor neurons in the spinal cord. In this work, we used X-ray diffraction technique to solve the structures of the three variant of the of SMN protein, namely SMN 1-4, SMN-WT, and SMN-delta7. The SMN 1-4, SMN-WT, and SMN-delta7 crystals were diffracted to 2.7 Å, 5.5 Å and 3.0 Å, respectively. The three-dimensional structures of the three SMN proteins have been solved. The FMO protein from Pld. phaeum is a water soluble protein that is embedded in the cytoplasmic membrane and serves as an energy transfer funnel between the chlorosome and the reaction center. The FMO crystal diffracted to 1.99Å resolution and the three-dimensional structure has been solved. In previous studies, double mutant, DX, protein was purified and crystallized in the presence of ATP (Simmons et al., 2010; Smith et al. 2007). DX is a synthetic ATP binding protein which resulting from a random selection of DNA library. In this study, DX protein was purified and crystallized without the presence of ATP to investigate the conformational change in DX structure. The crystals of DX were diffracted to 2.5 Å and the three-dimensional structure of DX has been solved.
Author : M. Sundaralingam
Publisher :
ISBN 13 :
Total Pages : 784 pages
Book Rating : 4.3/5 (91 download)
Download or read book Structure and Conformation of Nucleic Acids and Protein-nucleic Acid Interactions written by M. Sundaralingam and published by . This book was released on 1975 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: X-ray diffraction studies of tRNAs and synthetases; nmr and raman studieson nucleic acids and polynucleotides; Protein- nucleic acid (nucleotide) interactions; Protein- acid (nucleotide coenzyme) interactions; Structure and conformation of nucleic acids x- ray, nmr, and theory.
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kiyoshi Nagai
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.3/5 (91 download)
Download or read book RNA-protein Interactions written by Kiyoshi Nagai and published by Oxford University Press, USA. This book was released on 1994 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.
Author : E. Clementi
Publisher : Springer Science & Business Media
ISBN 13 : 1468453084
Total Pages : 454 pages
Book Rating : 4.4/5 (684 download)
Download or read book Structure and Dynamics of Nucleic Acids, Proteins, and Membranes written by E. Clementi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects a number of the invited lectures and a few selected contrib utions presented at the International Symposium on Structure and Dynamics of Nucleic Acids, Proteins and Membranes held August 31st through September 5th, 1986, in Riva del Garda, Italy. The title of the conference as well as a number of the topics covered represent a continuation of two previous conferences, the first held in 1982 at the University of California in San Diego, and the second in 1984 in Rome at the Accademia dei Lincei. These two earlier conferences have been documented in Structure and Dynamics: Nucleic Acids and Proteins, edited by E. Clementi and R. H. Sarma, Adenine Press, New York, 1983, and Structure and Motion: Membranes, Nucleic Acids and Proteins, edited by E. Clementi, G. Corongiu, M. H. Sarma and R. H. Sarma, Adenine Press, New York, 1985. At this conference in Riva del Garda we were very hesitant to keep the name of the conference the same as the two previous ones. Indeed, a number of topics discussed in this conference were not included in the previous ones and even the emphasis of this gathering is only partly reflected in the conference title. An alternative title would have been Structure and Dynamics of Nucleic Acids, Proteins, and Higher Functions, or, possibly, "higher components" rather than "higher functions.
Author : Jan Drenth
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)
Download or read book Principles of Protein X-ray Crystallography written by Jan Drenth and published by . This book was released on 1994 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals so set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive intro ductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses. Charles R. Cantor v Preface Macromolecules are the principal nonaqueous components of living cells. Among the macromolecules (proteins, nucleic acids, and carbohydrates), proteins are the largest group.
Author : Wing-Lun Law
Publisher :
ISBN 13 : 9781361262696
Total Pages : pages
Book Rating : 4.2/5 (626 download)
Download or read book Expression, Purification and Preliminary X-Ray Crystallographic Studies of Two Nucleotide Binding Proteins written by Wing-Lun Law and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Expression, Purification and Preliminary X-ray Crystallographic Studies of Two Nucleotide Binding Proteins" by Wing-lun, Law, 羅永倫, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b4693911 Subjects: Carrier proteins Nucleotides
Author : Xiaofei Jia
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (129 download)
Download or read book X-ray Crystallographic Studies of Cellular Retinoic Acid-binding Protein II Mutants Designed as Rhodopsin Mimics written by Xiaofei Jia and published by . This book was released on 2008 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Wing-lun Law
Publisher :
ISBN 13 :
Total Pages : 246 pages
Book Rating : 4.:/5 (772 download)
Download or read book Expression, Purification and Preliminary X-ray Crystallographic Studies of Two Nucleotide Binding Proteins written by Wing-lun Law and published by . This book was released on 2011 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Soheila Vaezeslami
Publisher :
ISBN 13 :
Total Pages : 530 pages
Book Rating : 4.3/5 (129 download)
Download or read book X-ray Crystallographic Studies of Mutants of Cellular Retinoic Acid Binding Protein (II) Toward Designing a Mimic of Rhodopsin written by Soheila Vaezeslami and published by . This book was released on 2006 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leonard J. Banaszak
Publisher : Elsevier
ISBN 13 : 0080521843
Total Pages : 180 pages
Book Rating : 4.0/5 (85 download)
Download or read book Foundations of Structural Biology written by Leonard J. Banaszak and published by Elsevier. This book was released on 2000-02-08 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features* Explains how to use coordinate databases and atomic coordinates of biological macromolecules* Teaches the skills of stereoviewing* Contains computer-generated stereographics* Describes the principles of symmetry and handedness in proteins and DNA* Introduces metal and lipid binding proteins and DNA-protein interactions* Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions
Author : Jonathan D. Dinman
Publisher : Springer Science & Business Media
ISBN 13 : 1461439914
Total Pages : 325 pages
Book Rating : 4.4/5 (614 download)
Download or read book Biophysical approaches to translational control of gene expression written by Jonathan D. Dinman and published by Springer Science & Business Media. This book was released on 2012-09-20 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a premier resource on understanding the ribosome's essential nature and how it interacts with other proteins and nucleic acids to control protein synthesis. As one of the central foundations in our understanding of the biology at the molecular level, this topic appeals to a wide audience, from bench researcher to clinician. With the advent of atomic scale structures, methods to visualize and separate individual molecules, and the computational power to model the complex interactions of over a million atoms at once, our understanding of how gene expression is controlled at the level of protein translation is now deeply ensconced in the biophysical realm.
Author : Stephen Neidle
Publisher : Oxford University Press on Demand
ISBN 13 : 0198500386
Total Pages : 662 pages
Book Rating : 4.1/5 (985 download)
Download or read book Oxford Handbook of Nucleic Acid Structure written by Stephen Neidle and published by Oxford University Press on Demand. This book was released on 1999 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Handbook of Nucleic Acid Structure is a comprehensive reference text on all aspects of nucleic acid sturcture. Particular emphasis is placed on the results from X-ray crystallography and NMR studies, with both methods being given equal weight. The nineteen chapters describe in detail the variety of DNA and RNA structural types discovered to date with all the major 'native' structures being represented. The text progresses systematically through the polymorphs of double helicalDNA through to the higher-order organizations of triplexes, quadruplexes, and junctions, then to RNA structures in their various degrees of complexity. Each chapter has been written by authorities in the field who have worked together to provide this comprehensive text on nucleic acid structure. The whole project has been brought together and edited by Professor Stephen Neidle who is Director of the CRC Biomolecular Structure Unit at the Institute of Cancer Research.
