When Blood Breaks Down

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When Blood Breaks Down

Author : Mikkael A. Sekeres
Publisher : MIT Press
ISBN 13 : 0262542250
Total Pages : 325 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis When Blood Breaks Down by : Mikkael A. Sekeres

Download or read book When Blood Breaks Down written by Mikkael A. Sekeres and published by MIT Press. This book was released on 2021-08-17 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading cancer specialist tells the powerful stories of 3 adult leukemia patients—shining new light on the hidden history of the disease and the drugs developed to treat it. “A look at leukemia patients’ fear, survival and grace while fighting the disease . . . a quiet chronicle of life with and beyond leukemia, and sometimes life’s end.” —The Washington Post When you are told that you have leukemia, your world stops. Your brain can’t function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together. Sekeres, who writes regularly for the “Well” section of The New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family’s wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimate conversations between Sekeres and his patients, and we watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it—describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia. The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

When Blood Breaks Down

Author : Mikkael A. Sekeres
Publisher : MIT Press
ISBN 13 : 0262043726
Total Pages : 325 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis When Blood Breaks Down by : Mikkael A. Sekeres

Download or read book When Blood Breaks Down written by Mikkael A. Sekeres and published by MIT Press. This book was released on 2020-04-21 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading cancer specialist tells the compelling stories of three adult leukemia patients, shedding new light on the disease itself and the drugs developed to treat it When you are told that you have leukemia, your world stops. Your brain can’t function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together. Sekeres, who writes regularly for the “Well” section of The New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family’s wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimate conversations between Sekeres and his patients, and we watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it—describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia. The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

Bad Blood

Author : John Carreyrou
Publisher : Vintage
ISBN 13 : 1524731668
Total Pages : 354 pages
Book Rating : 4.5/5 (247 download)

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Book Synopsis Bad Blood by : John Carreyrou

Download or read book Bad Blood written by John Carreyrou and published by Vintage. This book was released on 2018-05-21 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • The gripping story of Elizabeth Holmes and Theranos—one of the biggest corporate frauds in history—a tale of ambition and hubris set amid the bold promises of Silicon Valley, rigorously reported by the prize-winning journalist. With a new Afterword covering her trial and sentencing, bringing the story to a close. “Chilling ... Reads like a thriller ... Carreyrou tells [the Theranos story] virtually to perfection.” —The New York Times Book Review In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the next Steve Jobs: a brilliant Stanford dropout whose startup “unicorn” promised to revolutionize the medical industry with its breakthrough device, which performed the whole range of laboratory tests from a single drop of blood. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.5 billion. There was just one problem: The technology didn’t work. Erroneous results put patients in danger, leading to misdiagnoses and unnecessary treatments. All the while, Holmes and her partner, Sunny Balwani, worked to silence anyone who voiced misgivings—from journalists to their own employees.

Drugs and the FDA

Author : Mikkael A. Sekeres
Publisher : MIT Press
ISBN 13 : 0262047314
Total Pages : 319 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Drugs and the FDA by : Mikkael A. Sekeres

Download or read book Drugs and the FDA written by Mikkael A. Sekeres and published by MIT Press. This book was released on 2022-09-27 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the FDA was shaped by public health crises and patient advocacy, told against a background of the contentious hearings on the breast cancer drug Avastin. Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer’s drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate US authority on a drug’s safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA’s cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world. It took a series of tragedies and health crises, as well as patient advocacy, for the government to take responsibility for ensuring the efficacy and safety of drugs and medical devices. Before the FDA existed, drug makers could hawk any potion, claim treatment of any ailment, and make any promise on a label. But then, throughout the twentieth century, the government was forced to take action when children were poisoned by contaminated diphtheria and smallpox vaccines, an early antibiotic contained antifreeze, a drug prescribed for morning sickness in pregnancy caused babies to be born disfigured, and access to AIDS drugs was limited to a few clinical trials while thousands died. Sekeres describes all these events against the backdrop of the contentious 2011 hearings on the breast cancer drug Avastin, in which he participated as a panel member. The Avastin hearings, he says, put to the test a century of the FDA’s evolution, demonstrating how its system of checks and balances works—or doesn’t work.

What Happens When a Kid Has Cancer

Author : Sara Olsher
Publisher :
ISBN 13 : 9781736611463
Total Pages : 36 pages
Book Rating : 4.6/5 (114 download)

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Book Synopsis What Happens When a Kid Has Cancer by : Sara Olsher

Download or read book What Happens When a Kid Has Cancer written by Sara Olsher and published by . This book was released on 2021-04-23 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: When a child is diagnosed with cancer, life flips upside-down. Suddenly, our days (and our thoughts) are dominated by doctors, nurses, child life specialists, and a million technical terms that will make anyone's head spin. Add extreme fear and anxiety to that, and you've got a recipe for the most stressful time in a family's life.What Happens When a Kid Has Cancer is a book written with purpose of relieving the anxiety and confusion that comes from a child's cancer diagnosis and treatment.What Happens When a Kid Has Cancer covers the main points of pediatric cancer - what it is and what the experience of treatment is like - and shows how it can change a kid's day. The book is great for ages 4 -10 and discusses:- The science of cancer- Changes to routines- Surgery and anesthesia - Chemotherapy- Hair loss and hair changes- Port, central line, and tubies- Hospital stays- Radiation- Scans and blood draws- Emotions relating to cancerOver the course of a year and with the help of both experts and families who have been through pediatric cancer, author and illustrator Sara Olsher explains the science of cancer (in an age-appropriate, totally non-scary way) and uses an illustrated calendar to show how various treatments affect a child's day-to-day. This method of teaching is based on decades of solid science about how kids learn and cope with the major day-to-day changes that result from issues like cancer. By creating a routine that kids can see and understand, parents can restore a sense of safety and predictability in their kids' lives, helping them to be more resilient in the face of life's inevitable challenges. What Happens When a Kid Has Cancer? helps families that want to reduce their kids' anxiety surrounding a very scary diagnosis. It aims to empower kids with knowledge, which is proven to help kids through traumatic situations.

Drugs and the FDA

Author : Mikkael A. Sekeres
Publisher : MIT Press
ISBN 13 : 0262548399
Total Pages : 319 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Drugs and the FDA by : Mikkael A. Sekeres

Download or read book Drugs and the FDA written by Mikkael A. Sekeres and published by MIT Press. This book was released on 2024-02-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the FDA was shaped by public health crises and patient advocacy, told against a background of the contentious hearings on the breast cancer drug Avastin. Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer’s drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate US authority on a drug’s safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA’s cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world. It took a series of tragedies and health crises, as well as patient advocacy, for the government to take responsibility for ensuring the efficacy and safety of drugs and medical devices. Before the FDA existed, drug makers could hawk any potion, claim treatment of any ailment, and make any promise on a label. But then, throughout the twentieth century, the government was forced to take action when children were poisoned by contaminated diphtheria and smallpox vaccines, an early antibiotic contained antifreeze, a drug prescribed for morning sickness in pregnancy caused babies to be born disfigured, and access to AIDS drugs was limited to a few clinical trials while thousands died. Sekeres describes all these events against the backdrop of the contentious 2011 hearings on the breast cancer drug Avastin, in which he participated as a panel member. The Avastin hearings, he says, put to the test a century of the FDA’s evolution, demonstrating how its system of checks and balances works—or doesn’t work.

The Breakthrough

Author : Charles Graeber
Publisher : Hachette+ORM
ISBN 13 : 145556849X
Total Pages : 314 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis The Breakthrough by : Charles Graeber

Download or read book The Breakthrough written by Charles Graeber and published by Hachette+ORM. This book was released on 2015-12-01 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

The Emperor of All Maladies

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Wasted Wombs

Author : Erica van der Sijpt
Publisher : Vanderbilt University Press
ISBN 13 : 0826504027
Total Pages : 324 pages
Book Rating : 4.8/5 (265 download)

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Book Synopsis Wasted Wombs by : Erica van der Sijpt

Download or read book Wasted Wombs written by Erica van der Sijpt and published by Vanderbilt University Press. This book was released on 2018-03-27 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Central to this book are Gbigbil women's experiences with different "reproductive interruptions": miscarriages, stillbirths, child deaths, induced abortions, and infertility. Rather than consider these events as inherently dissimilar as women do in Western countries, the Gbigbil women of eastern Cameroon see them all as instances of "wasted wombs" that leave their reproductive trajectories hanging in the balance. The women must navigate this uncertainty while negotiating their social positions, aspirations for the future, and the current workings of their bodies. Providing an intimate look into these processes, Wasted Wombs shows how Gbigbil women constantly shift their interpretations of when a pregnancy starts, what it contains, and what is lost in case of a reproductive interruption, in contrast to Western conceptions of fertility and loss. Depending on the context and on their life aspirations--be it marriage and motherhood, or an educational trajectory and employment, or profitable sexual affairs with so-called "big fish"--women negotiate and manipulate the meanings and effects of reproductive interruptions. Paradoxically, they often do so while portraying themselves as powerless. Wasted Wombs carefully analyzes such tactics in relation to the various social predicaments that emerge around reproductive interruptions, as well as the capricious workings of women's physical bodies.

Anatomy and Physiology

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

State of New York Supreme Court Appellate Division Fourth Department

Author :
Publisher :
ISBN 13 :
Total Pages : 1178 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis State of New York Supreme Court Appellate Division Fourth Department by :

Download or read book State of New York Supreme Court Appellate Division Fourth Department written by and published by . This book was released on with total page 1178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Color Theory for the Make-up Artist

Author : Katie Middleton
Publisher : Taylor & Francis
ISBN 13 : 1000599310
Total Pages : 239 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Color Theory for the Make-up Artist by : Katie Middleton

Download or read book Color Theory for the Make-up Artist written by Katie Middleton and published by Taylor & Francis. This book was released on 2022-10-19 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Color Theory for the Make-up Artist: Understanding Color and Light for Beauty and Special Effects (Second Edition) analyzes and explains traditional color theory for fine artists and applies it to make-up artistry. This beautifully illustrated guide begins with the basics of color theory – why we see color, how to categorize and identify color, and relationships between colors – and relates these concepts to beauty and special effects make-up. The book provides a wealth of information, including how to mix flesh tones by using only primary colors, how these colors in paints and make-up are sourced and created, the reason for variations in skin colors and undertones, and how to identify and match these using make-up while choosing flattering colors for the eyes, lips, and cheeks. Colors found inside the body are explained for special effects make-up, like why we bruise, bleed, or appear sick. Ideas and techniques are also described for painting prosthetics, in addition to using color as inspiration in make-up designs. The book also discusses how lighting affects color on film, television, theater, and photography sets, and how to properly light a workspace for successful applications. The second edition features: A brand-new chapter on color inspiration in make-up and design Additional and updated diagrams More real-life application photos and demonstrations, including new examples of tattoo covering and prosthetic painting using optical mixtures, airbrush, and stippling Expanded discussion on undertones, skin variations, color correction, pigments, colored gels, and more Filled with stunning photography and practical information, Color Theory for the Make-up Artist provides guidance and inspiration for both professionals and beginners who wish to train their eye further to understand and recognize distinctions in color.

When Breath Becomes Air

Author : Paul Kalanithi
Publisher : Random House
ISBN 13 : 1473523494
Total Pages : 260 pages
Book Rating : 4.4/5 (735 download)

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Book Synopsis When Breath Becomes Air by : Paul Kalanithi

Download or read book When Breath Becomes Air written by Paul Kalanithi and published by Random House. This book was released on 2016-02-04 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: **THE MILLION COPY BESTSELLER** 'Rattling. Heartbreaking. Beautiful,' Atul Gawande, bestselling author of Being Mortal What makes life worth living in the face of death? At the age of thirty-six, on the verge of completing a decade's training as a neurosurgeon, Paul Kalanithi was diagnosed with inoperable lung cancer. One day he was a doctor treating the dying, the next he was a patient struggling to live. When Breath Becomes Air chronicles Kalanithi's transformation from a medical student asking what makes a virtuous and meaningful life into a neurosurgeon working in the core of human identity - the brain - and finally into a patient and a new father. Paul Kalanithi died while working on this profoundly moving book, yet his words live on as a guide to us all. When Breath Becomes Air is a life-affirming reflection on facing our mortality and on the relationship between doctor and patient, from a gifted writer who became both. 'A vital book about dying. Awe-inspiring and exquisite. Obligatory reading for the living' Nigella Lawson

A Manual for the Practice of Surgery

Author : Thomas Bryant
Publisher :
ISBN 13 :
Total Pages : 710 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis A Manual for the Practice of Surgery by : Thomas Bryant

Download or read book A Manual for the Practice of Surgery written by Thomas Bryant and published by . This book was released on 1879 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Winchester v. Meads, 372 MICH 593 (1964)

Author :
Publisher :
ISBN 13 :
Total Pages : 492 pages
Book Rating : 4.L/5 ( download)

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Book Synopsis Winchester v. Meads, 372 MICH 593 (1964) by :

Download or read book Winchester v. Meads, 372 MICH 593 (1964) written by and published by . This book was released on 1964 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: 36

Your Skin and Bones

Author : Melanie Waldron
Publisher : Capstone Classroom
ISBN 13 : 1410959864
Total Pages : 50 pages
Book Rating : 4.4/5 (19 download)

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Book Synopsis Your Skin and Bones by : Melanie Waldron

Download or read book Your Skin and Bones written by Melanie Waldron and published by Capstone Classroom. This book was released on 2014-01-01 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the human skeleton, muscles, and skin, discussing their composition, structure, functions, and disorders.

Campbell's Physiology Notes For Nurses

Author : John Campbell
Publisher : John Wiley & Sons
ISBN 13 : 0470032413
Total Pages : 208 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Campbell's Physiology Notes For Nurses by : John Campbell

Download or read book Campbell's Physiology Notes For Nurses written by John Campbell and published by John Wiley & Sons. This book was released on 2006-02-22 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This accessible and friendly text is based on the premise that all nurses need a working knowledge of the normal functioning of the human body. It is only when we understand the normal that the abnormal pathological situation makes sense. If we can understand how the body goes wrong then it often becomes obvious what needs to be done to treat the disorder. So physiology and pathophysiology can both be used to inform our clinical interventions and provide us with rationales for care. In this concise text, John Campbell explains the physiology and necessary basic science in a way that is easy to understand and learn. Diagrams are an important part of this philosophy.