Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Volume Ii Novel Molecular Mechanisms And Innovative Therapeutic Approaches For Age Associated Diseases
Download Volume Ii Novel Molecular Mechanisms And Innovative Therapeutic Approaches For Age Associated Diseases full books in PDF, epub, and Kindle. Read online Volume Ii Novel Molecular Mechanisms And Innovative Therapeutic Approaches For Age Associated Diseases ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Volume II: Novel molecular mechanisms and innovative therapeutic approaches for age-associated diseases by : Leming Sun
Download or read book Volume II: Novel molecular mechanisms and innovative therapeutic approaches for age-associated diseases written by Leming Sun and published by Frontiers Media SA. This book was released on 2023-01-09 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Novel Molecular Mechanisms and Innovative Therapeutic Approaches for Age-Associated Diseases by : Leming Sun
Download or read book Novel Molecular Mechanisms and Innovative Therapeutic Approaches for Age-Associated Diseases written by Leming Sun and published by Frontiers Media SA. This book was released on 2022-06-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Role of Nrf2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches by : Javier Egea
Download or read book Role of Nrf2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches written by Javier Egea and published by Frontiers Media SA. This book was released on 2020-01-02 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurotrophins Biodelivery to CNS: Innovative Approaches for Disease-Modifying Therapy by : Viviana Triaca
Download or read book Neurotrophins Biodelivery to CNS: Innovative Approaches for Disease-Modifying Therapy written by Viviana Triaca and published by Frontiers Media SA. This book was released on 2022-06-01 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Novel Anti-inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies by : Carla Maria Pedrosa Ribeiro
Download or read book Novel Anti-inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies written by Carla Maria Pedrosa Ribeiro and published by Frontiers Media SA. This book was released on 2022-01-04 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurodegeneration: From Genetics to Molecules, Volume II by : Victoria Campos-Peña
Download or read book Neurodegeneration: From Genetics to Molecules, Volume II written by Victoria Campos-Peña and published by Frontiers Media SA. This book was released on 2022-01-24 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Encyclopedia of Biomedical Gerontology by :
Download or read book Encyclopedia of Biomedical Gerontology written by and published by Academic Press. This book was released on 2019-11-20 with total page 1656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Biomedical Gerontology, Three Volume Set presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention. Provides a ‘one-stop’ resource to information written by world-leading scholars in the field of biomedical gerontology Fills a critical gap of information in a field that has seen significant progress in the last 10 years
Book Synopsis Innovative approaches and therapeutic perspectives for early-onset neurodevelopmental disorders: from bench to bedside. by : Barbara Bardoni
Download or read book Innovative approaches and therapeutic perspectives for early-onset neurodevelopmental disorders: from bench to bedside. written by Barbara Bardoni and published by Frontiers Media SA. This book was released on 2024-03-11 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: In partnership with the Jacques Monod Conference “Genetics, environment, signaling & synaptic plasticity in developmental brain disorders: from bench to bedside", the Frontiers in Neuroscience Journal announces an article collection that will highlight cutting-edge research presented at the 2022 meeting from Monday 11th Apr - Friday 15th Apr in Roscoff (Brittany). Neurodevelopmental Disorders (NDDs) are a highly heterogeneous group of disorders with a prevalence of 3% of the worldwide population. These disorders include Intellectual Disability (ID), autism spectrum disorder (ASD), attention deficit hyperactivity disorder, specific learning disorder, motor and language disorder, schizophrenia, and epilepsy. Thus, NDDs are characterized by deficits in cognition, social interaction, behavior, and motor functioning as a result of abnormal brain development. Several of these phenotypes can co-exist in the same patient. Indeed, for instance, up to 50% of ASD patients display also ID. Similarly, the prevalence of epilepsy in ID patients is around 26%. This phenotypic overlap is also mirrored at the genetic and molecular levels. For instance, some pathways (e.g., Rho-GTPase, group I mGluRs, cAMP and WNT) have been found to be altered in different forms of NDDs, both of genetic and environmental origin.
Book Synopsis Neuroinflammation, Neurodegeneration and Metabolic Disease: From Molecular Mechanisms to Therapeutic Innovation by : Fawaz Alzaid
Download or read book Neuroinflammation, Neurodegeneration and Metabolic Disease: From Molecular Mechanisms to Therapeutic Innovation written by Fawaz Alzaid and published by Frontiers Media SA. This book was released on 2024-09-05 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroinflammation manifests as changes to cognition or behavior, or as altered function in peripheral tissues. Patients with metabolic diseases (e.g., diabetes, obesity) are more likely to suffer with neuroinflammation since the disrupted metabolism and chronic low-grade inflammation that accompany metabolic diseases extends to the nervous system. Neuroinflammation will then lead to functional impairment and progressive loss of neuronal structure, with neurodegeneration being the end result. Factors like chronic hyperglycemia, dyslipidemia and insulin resistance are candidate drivers of neuroinflammation and neurodegeneration. The effects on the nervous system also contribute to worsening insulin resistance and a further loss of metabolic function and homeostasis in innervated peripheral tissues (e.g., liver, adipose tissue). Persistent metabolic stress predisposes patients to peripheral neuropathies, cognitive dysfunction, and development of neurodegenerative diseases (e.g., Alzheimer’s disease). Multiple associations link metabolic disease to neuropathology, targeting neuroinflammation to preserve neuronal integrity holds promise for managing metabolic diseases and associated neurological complications. Research on "Neuroinflammation, Neurodegeneration and Metabolic Disease: From Molecular Mechanisms to Therapeutic Innovation" is necessary to address several critical gaps in our understanding and treatment of metabolic diseases and of neuropathology. Firstly, while the role of systemic inflammation in metabolic diseases has been extensively studied, the specific impact of nervous system inflammation – neuroinflammation – and resulting neurodegeneration on these conditions is still an emerging field. Investigating the mechanisms by which neuroinflammation and neurodegeneration contribute to metabolic diseases can provide valuable insights into the pathogenesis and progression of these conditions.
Book Synopsis Characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases, 2nd edition by : Chengjin Gao
Download or read book Characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases, 2nd edition written by Chengjin Gao and published by Frontiers Media SA. This book was released on 2024-11-06 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systemic inflammatory response is evident in inflammatory diseases, and the immune system secretes many cytokines involved, resulting in a robust immune response. For example, the pathogenesis of sepsis includes abnormal immune cell activation in the early stages as well as sepsis-related immunosuppression. During the immunosuppressive phase, CD4+ T cells, CD8+ T cells, Th17 cells, and ?d T cells are reduced while regulatory T cells increase. At the same time, T lymphocytes and neutrophils, as immune effector cells, interact with each other and play a key role in regulating the immune response to immune-inflammatory diseases. The increased release of neutrophil extracellular trap networks (NETs) by neutrophils leads to a significant upregulation of NETs-DNA-MPO, which further aggravates the septic inflammatory response and organ functional impairment. Therefore, it is important to deeply investigate the characteristic clinical immune phenotypes and molecular mechanisms associated with inflammatory diseases, and targeting therapies against them may provide new ideas for the precise treatment of diseases. The goal of this Research Topic is to provide a forum to advance research on the contribution of the fundamental mechanisms of immune system development and function, with special emphasis on the description and mechanism of clinical immunological phenotypes in different immune disorders and the definition of their molecular basis. The Research Topic had the bullet points including but not limited to the following: 1) Description of the immune phenotypes of various common acute and chronic diseases; 2) The regulatory mechanisms of different factors on the development and function of the host immune system; 3) Inflammatory immunological mechanisms, organ function, and interorgan interactions.
Book Synopsis The Physiology of Inflammation – The Final Common Pathway to Disease by : Alexandrina Ferreira Mendes
Download or read book The Physiology of Inflammation – The Final Common Pathway to Disease written by Alexandrina Ferreira Mendes and published by Frontiers Media SA. This book was released on 2019-02-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation "low grade". This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies.
Book Synopsis Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment by : Ruowen Zhang
Download or read book Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment written by Ruowen Zhang and published by Frontiers Media SA. This book was released on 2024-09-20 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal (GI) cancer, the group of cancers that affect the gastrointestinal tract and other organs that are contained within the digestive system, including the esophagus, pancreas, stomach, colon, rectum, anus, liver, biliary system and small intestine, is the most common malignant diseases with high mortality rates, leading to a substantial burden on public health and healthcare systems around the world. Diverse subtypes of GI cancer impressively exhibit similar characteristics like high frequency oncogenic mutation burden, early metastatic potency, chemo-resistance and immunotherapeutic tolerance indicating a possible unique tumorigenic mechanism.
Book Synopsis Anti-Aging Pharmacology by : Vitaly Koltover
Download or read book Anti-Aging Pharmacology written by Vitaly Koltover and published by Academic Press. This book was released on 2022-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world's leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice. - Includes updated information about current developments in anti-aging pharmacology - Offers practical advice on the applicability of certain healthspan-promoting medications - Discusses potential challenges related to the translation of anti-aging drugs in clinical practice
Book Synopsis Women in Molecular Mechanisms of Aging Research by : Consuelo Borras
Download or read book Women in Molecular Mechanisms of Aging Research written by Consuelo Borras and published by Frontiers Media SA. This book was released on 2024-11-07 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are delighted to present the inaugural Frontiers in Aging 'Women in Molecular Mechanisms of Aging Research' series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women to enter science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. To change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers. Therefore, Frontiers in Aging is proud to offer this platform to promote the work of women scientists who are involved in research in the field of aging and related molecular mechanisms. The work presented in this Research Topic highlights the diversity of research performed and presents advances in theory, experiment, and methodology with applications to compelling problems, covering the following aspects, but not limited to: - Sex differences in molecular mechanisms of aging - Sex dimorphism in age-related diseases - Perspectives on the future of Molecular Mechanisms of Aging Research - Molecular Mechanisms of Aging Research and its impact on older women - Articles spotlighting excellent female-led contributions to the field of Aging - Perspectives on a specific field of Molecular Mechanisms of Aging Research inspired, started, or sparked by a woman - Research on gender disparities in healthcare in aging
Book Synopsis Translational Advances in Alzheimer's, Parkinson's, and other Dementia: Molecular Mechanisms, Biomarkers, Diagnosis, and Therapies, Volume II by : Jiehui Jiang
Download or read book Translational Advances in Alzheimer's, Parkinson's, and other Dementia: Molecular Mechanisms, Biomarkers, Diagnosis, and Therapies, Volume II written by Jiehui Jiang and published by Frontiers Media SA. This book was released on 2022-11-15 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Novel Diagnostic and Therapeutic Strategies for Retinal Diseases by : Shaochong Zhang
Download or read book Novel Diagnostic and Therapeutic Strategies for Retinal Diseases written by Shaochong Zhang and published by Frontiers Media SA. This book was released on 2022-10-25 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Review on Diverse Neurological Disorders by : Rameshwar Nath Chaurasia
Download or read book A Review on Diverse Neurological Disorders written by Rameshwar Nath Chaurasia and published by Elsevier. This book was released on 2024-06-05 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to World Health Organization (WHO) one billion people worldwide are affected by one of the thousands of neurological disorders, including epilepsy, Alzheimer disease, strokes, and headaches. Neurological disorders also include brain injuries, neuroinfections, multiple sclerosis and Parkinson disease. A Review on Neurological Disorders: Pathophysiology, Molecular Mechanisms, and Therapeutics covers the major topics related to neurological disorders, current challenges in diagnosis and intervention. This book is organized into four distinct sections, starting with an introduction, providing a general overview of the epidemiology of neurological disorders, pathogenesis and management. The second section presents the aspects of brain diseases due to infection of bacteria, parasite, fungus and viruses. The third section discusses neurodegenerative disorders due to comorbid factors like diabetes, hypertension, hyperlipidemia and post traumatic brain injuries. The last section covers prevention through application of bioactive compounds and neuroprotective agents. - Epidemiology of neurological disorders and pathogenesis. - Explores neuroinflammation, ligand-receptors binding, and neurodegeneration. - Discusses aging and associated disorders in the onset of neurological disorders. - Neuropharmacology and the protective role of bioactive compounds in neuroprotection.
