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Vitamin D And Cholesterol
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Book Synopsis Vitamin D and Cholesterol by : David S. Grimes
Download or read book Vitamin D and Cholesterol written by David S. Grimes and published by YPD-BOOKS. This book was released on 2009 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its discovery in the early years of the 20th Century, and its use as the treatment of childhood rickets, vitamin D has become neglected. This book sets out to explain why these things have happened, explaining how the benefits of vitamin D extend beyond healthy bones to a vital role in the development of immunity.
Book Synopsis The Great Cholesterol Myth, Revised and Expanded by : Jonny Bowden
Download or read book The Great Cholesterol Myth, Revised and Expanded written by Jonny Bowden and published by Fair Winds Press. This book was released on 2020-08-04 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best-selling book on heart disease, updated with the latest research and clinical findings on high-fat/ketogenic diets, sugar, genetics, and other factors. Heart disease is the #1 killer. However, traditional heart disease protocols—with their emphasis on lowering cholesterol—have it all wrong. Emerging science is showing that cholesterol levels are a poor predictor of heart disease and that standard prescriptions for lowering it, such as ineffective low-fat/high-carb diets and serious, side-effect-causing statin drugs, obscure the real causes of heart disease. Even doctors at leading institutions have been misled for years based on creative reporting of research results from pharmaceutical companies intent on supporting the $31-billion-a-year cholesterol-lowering drug industry. The Great Cholesterol Myth reveals the real culprits of heart disease, including: inflammation, fibrinogen, triglycerides, homocysteine, belly fat, triglyceride to HDL ratios, and high glycemic levels. Best-selling health authors Jonny Bowden, PhD, and Stephen Sinatra, MD, give readers a four-part strategy based on the latest studies and clinical findings for effectively preventing, managing, and reversing heart disease, focusing on diet, exercise, supplements, and stress and anger management. Myths vs. Facts Myth: High cholesterol is the cause of heart disease. Fact: Cholesterol is only a minor player in the cascade of inflammation which is a cause of heart disease. Myth: Saturated fat is dangerous. Fact: Saturated fats are not dangerous. The killer fats are the transfats from partially hydrogenated oils. â?? Myth: The higher the cholesterol, the shorter the lifespan. Fact: Higher cholesterol protects you from gastrointestinal disease, pulmonary disease, and hemorrhagic stroke. Myth: High cholesterol is a predictor of heart attack. Fact: There is no correlation between cholesterol and heart attacks. Myth: Lowering cholesterol with statin drugs will prolong your life. Fact: There is no data to show that statins have a significant impact on longevity. Myth: Statin drugs are safe. Fact: Statin drugs can be extremely toxic including causing death. Myth: Statin drugs are useful in men, women, and the elderly. Fact: Statin drugs do the best job in middle-aged men with coronary disease. Myth: Statin drugs are useful in middle-aged men with coronary artery disease because of its impact on cholesterol. Fact: Statin drugs reduce inflammation and improve blood viscosity (thinning blood). Statins are extremely helpful in men with low HDL and coronary artery disease.
Book Synopsis Vitamin D Receptor (VDR) and Cholesterol Homeostasis by : Holly Quach
Download or read book Vitamin D Receptor (VDR) and Cholesterol Homeostasis written by Holly Quach and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D deficiency is speculated to play a role in hypercholesterolemia. However, there has been little molecular evidence to link the two until recent evidence identified the vitamin D receptor (VDR) and its natural ligand, 1Îą,25-dihydroxyvitamin D3 [1,25(OH)2D3], as key regulators of cholesterol metabolism. In the liver, 1,25(OH)2D3-liganded VDR directly inhibited the small heterodimer partner (Shp) to increase expression of cholesterol 7Îą-hydroxylase (Cyp7a1), the rate-limiting enzyme for cholesterol metabolism to bile acids, a mechanism independent of the farnesoid X receptor. Vitamin D deficiency was established in mice after 8 weeks of the D-deficient diet, which resulted in decreased levels of plasma and liver 1,25(OH)2D3, downregulation of hepatic Vdr and Cyp7a1, and elevation of Shp. Consequently, higher plasma and liver cholesterol levels were observed. Intervention with 1,25(OH)2D3 or vitamin D3 reversed the altered expression of these cholesterol-regulating genes and lowered cholesterol levels back to baseline levels. The correlations between liver cholesterol vs. liver 1,25(OH)2D3 and Cyp7a1 expression in mice were also found in human liver tissue, suggesting that the VDR could be a potential therapeutic target for cholesterol lowering. However, the therapeutic utility of 1,25(OH)2D3 is limited by hypercalcemia and by its feedback control mechanisms. When given exogenously, 1,25(OH)2D3 triggered inhibition of its synthesis enzyme (Cyp27b1) but induction of its degradation enzyme (Cyp24a1) in a dose-dependent manner, events that are predicted by compartmental and physiologically-based pharmacokinetic/pharmacodynamic modeling. These models provide a foundation for predicting 1,25(OH)2D3 disposition for inter-species scaling and for exploration of alternative dosing schemes and routes of administration to describe the dynamics of 1,25(OH)2D3 in its new therapeutic roles. Overall, these findings highlight the importance of vitamin D status and the VDR as regulators of hypercholesterolemia.
Book Synopsis Nutrition and Traumatic Brain Injury by : Institute of Medicine
Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Book Synopsis Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride by : Institute of Medicine
Download or read book Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride written by Institute of Medicine and published by National Academies Press. This book was released on 1999-10-17 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1941, Recommended Dietary Allowances (RDAs) has been recognized as the most authoritative source of information on nutrient levels for healthy people. Since publication of the 10th edition in 1989, there has been rising awareness of the impact of nutrition on chronic disease. In light of new research findings and a growing public focus on nutrition and health, the expert panel responsible for formulation RDAs reviewed and expanded its approachâ€"the result: Dietary Reference Intakes. This new series of references greatly extends the scope and application of previous nutrient guidelines. For each nutrient the book presents what is known about how the nutrient functions in the human body, what the best method is to determine its requirements, which factors (caffeine or exercise, for example) may affect how it works, and how the nutrient may be related to chronic disease. The first volume of Dietary Reference Intakes includes calcium, phosphorus, magnesium, vitamin D, and fluoride. The second book in the series presents information about thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Based on analysis of nutrient metabolism in humans and data on intakes in the U.S. population, the committee recommends intakes for each age groupâ€"from the first days of life through childhood, sexual maturity, midlife, and the later years. Recommendations for pregnancy and lactation also are made, and the book identifies when intake of a nutrient may be too much. Representing a new paradigm for the nutrition community, Dietary Reference Intakes encompasses: Estimated Average Requirements (EARs). These are used to set Recommended Dietary Allowances. Recommended Dietary Allowances (RDAs). Intakes that meet the RDA are likely to meet the nutrient requirement of nearly all individuals in a life-stage and gender group. Adequate Intakes (AIs). These are used instead of RDAs when an EAR cannot be calculated. Both the RDA and the AI may be used as goals for individual intake. Tolerable Upper Intake Levels (ULs). Intakes below the UL are unlikely to pose risks of adverse health effects in healthy people. This new framework encompasses both essential nutrients and other food components thought to pay a role in health, such as dietary fiber. It incorporates functional endpoints and examines the relationship between dose and response in determining adequacy and the hazards of excess intake for each nutrient.
Book Synopsis Ultraviolet Light in Human Health, Diseases and Environment by : Shamim I. Ahmad
Download or read book Ultraviolet Light in Human Health, Diseases and Environment written by Shamim I. Ahmad and published by Springer. This book was released on 2017-11-08 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the roles and importance of Ultraviolet (UV) light from sun and from man-made UV lamps in our daily life, on health and diseases, also its application in sterilization and treatment. The key words are: reactive oxygen species, DNA damage, UV mutagenicity, skin cancers, polymorphous light eruption, Xeroderma pigmentosum, vitiligo, psoriasis, rheumatoid arthritis, diabetes mellitus, metabolic syndromes, cardiovascular diseases, dermatology, photobiology, photodermatosis, vitamin D synthesis, vitamin D efficiency, water sterilization, blood sterilization, phototherapies, skin tanning and UV dosimeter. The book starts with introduction to UV light and the history of development of UV lamps and its applications. It then moves to describing the interaction of this light with biological components and the production of reactive oxygen species, their roles in cell signaling, cellular defense from foreign invaders, in mutagenesis leading to skin diseases including vitiligo, polymorphous light eruption and various forms of skin cancer. Then it presents the synthesis and importance of UV light and diseases, induced due to the deficiency of vitamin D. Roles of UV light in sterilization, disinfection, phototherapies are depicted in the next part and finally use and abuse of UV light in tanning salon and the availability and importance of use of UV dosimeter are highlighted. The three main focuses of this book are: - Damage to biological systems by UV light leading to certain skin diseases; most importantly skin cancers. - Importance of UV light in the in vivo synthesis of vitamin D when human bodies are exposed to it. - Diseases caused due to the deficiency of vitamin D and the use of UV lamps in phototherapy and sterilization processes. The editor has considerable experience in publishing medical books and has used it critically selecting the matters which will attract the readers from many areas of medical and non-medical fields. It is hoped that the materials presented in this book will give great benefit and will stimulate both novice and expert researchers in the field. The book gives excellent overviews of the current status of research and pointers to the future research achievements. Clinicians, medical general practitioners, technicians and staff working in UV related industries and especially those working in tanning salon should benefit from the information presented in safe handling of this light.
Book Synopsis The Effect of Vitamin D and Cholesterol on Capillary Permeability by : Alene Freudenheim Silver
Download or read book The Effect of Vitamin D and Cholesterol on Capillary Permeability written by Alene Freudenheim Silver and published by . This book was released on 1947 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Fat-Soluble Vitamins by : H. DeLuca
Download or read book The Fat-Soluble Vitamins written by H. DeLuca and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first demonstration of the existence of a vitamin and the full recognition of this fact are often attributed to the work of McCollum, who found that a sub stance in butterfat and cod-liver oil was necessary for growth and health of ani mals fed purified diets. It became obvious that an organic substance present in microconcentrations was vital to growth and reproduction of animals. Following the coining of the word vitamine by Funk, McCollum named this fat-soluble sub stance vitamin A. We can, therefore, state that vitamin A was certainly one of the first known vitamins, yet its function and the function of the other fat-soluble vitamins had remained largely unknown until recent years. However, there has been an explosion of investigation and new information in this field, which had remained quiescent for at least two or three decades. It is now obvious that the fat-soluble vitamins function quite differently from their water-soluble counter parts. We have learned that vitamin D functions by virtue of its being converted in the kidney to a hormone that functions to regulate calcium and phosphorus metabolism. This new endocrine system is in the process of being elucidated in detail, and in addition, the medical use of these hormonal forms of vitamin D in the treatment of a variety of metabolic bone diseases has excited the medical com munity.
Book Synopsis Diet and Health by : National Research Council
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Book Synopsis Cholesterol Down by : Janet Bond Brill, PhD, RD, LDN
Download or read book Cholesterol Down written by Janet Bond Brill, PhD, RD, LDN and published by Harmony. This book was released on 2009-01-21 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Take control of your cholesterol with this 10-point plan from nutrition and fitness expert Dr. Janet Brill—without using drugs. If you are one of the nearly 100 million Americans struggling with high cholesterol, then Dr. Janet Brill offers you a revolutionary new plan for taking control of your health—without the risks of statin drugs. With Dr. Brill’s breakthrough Cholesterol Down Plan, you simply add nine “miracle foods” to your regular diet and thirty minutes of walking to your daily routine. That’s all. This straightforward and easy-to-follow program can lower your LDL (“bad”) cholesterol by as much as 47 percent in just four weeks. Cholesterol Down explains Dr. Brill’s ten-point plan as well as the science behind it. You’ll learn how each miracle food affects LDL cholesterol and how the foods work together for maximum effect, as well as: • How eating whole grains helps reduce LDL cholesterol in your bloodstream • Why antioxidants keep plaque from building up in your arteries • How certain steps change the structure of LDL cholesterol particles (and why it’s best for them to be large and fluffy) • Why walking just thirty minutes a day lowers “bad” cholesterol and cuts dangerous belly fat With everything you need to stay focused on the plan, including a daily checklist, a six-month chart for racking LDL cholesterol changes, tools for assessing your risk level for cardiovascular disease, sample weekly menus, and even heart-healthy recipes, Cholesterol Down is the safe and effective alternative or complement to statin drugs.
Book Synopsis Lipoproteins in Health and Disease by : John Betteridge
Download or read book Lipoproteins in Health and Disease written by John Betteridge and published by CRC Press. This book was released on 1999-04-02 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive work deals with the major health problem of high lipid levels in blood, a cause of serious heart and vascular disease. Formerly the province only of the chemical pathologist, cardiologists and general physicians are now offering treatment as new 'lipid-lowering' drugs become available. The area is also of considerable interest to public health physicians as changes in lifestyle (such as dietary and smoking habits) have significant effects on lipid levels. A prestigious team of contributors covers all aspects of the topic, from molecular biology to practical dietary management to help reduce lipid levels.
Download or read book Nutrigenomics written by Carsten Carlberg and published by Springer. This book was released on 2016-06-11 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively. Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.
Download or read book Vitamin D written by Michael F. Holick and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter refer virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authori ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences.
Book Synopsis Survival of the Sickest LP by : Dr. Sharon Moalem
Download or read book Survival of the Sickest LP written by Dr. Sharon Moalem and published by Harper Collins. This book was released on 2007-05-22 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Was diabetes evolution's response to the last Ice Age? Did a deadly genetic disease help our ancestors survive the bubonic plagues of Europe? Will a visit to the tanning salon help lower your cholesterol? Why do we age? Why are some people immune to HIV? Can your genes be turned on—or off? Survival of the Sickest is fi lled with fascinating insights and cutting-edge research, presented in a way that is both accessible and utterly absorbing. This is a book about the interconnectedness of all life on earth—and especially what that means for us. Read it. You're already living it.
Book Synopsis Foods to lower cholesterol by : Owen Jones
Download or read book Foods to lower cholesterol written by Owen Jones and published by Tektime. This book was released on 2022-06-27 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: I hope that you will find the information helpful and useful. Cholesterol is quite a buzz word these days, because the balance that you have literally means life or death. However, there are still several schools of thought that claim to be right. It makes decision-making regarding food for most of us very difficult. I hope that this booklet will spark your interest enough to look into the subject more deeply. The information in this audiobook on cholesterol and related subjects is organized into 17 chapters of about 500-600 words each. It will help you set understand and manage your cholesterol levels, and it may even help you stay off tablets. As an added bonus, I am granting you permission to use the content on your own website or in your own blogs and newsletter, although it is better if you rewrite them in your own words first. Translator: Owen Jones PUBLISHER: TEKTIME
Book Synopsis Studies on Atherosclerosis by : Martin Rodriguez-Porcel
Download or read book Studies on Atherosclerosis written by Martin Rodriguez-Porcel and published by Springer. This book was released on 2016-12-22 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the role free radicals and antioxidants within the development of vascular disease, examining fundamental research and translating preclinical knowledge to clinical trials. The expertly authored chapters describe the relationship of oxidative stress to atherosclerosis and the cardiovascular system, exploring its role in cardiac fibrosis, renovascular disease, hypertension, and regulation of blood pressure and cerebral vascular tone. The concluding chapter discusses the current state of clinical research, contextualizing clinical trials within the existing theoretical framework and analyzing attempts to preserve oxidant stress under various conditions. With its concise and authoritative analysis of pre-clinical research and clinical results, Studies in Atherosclerosis – part of the bestselling Oxidative Stress in Basic Research and Clinical Practice series – is essential for researchers and clinicians focusing in cardiology, nephrology, or oxidative stress.
Book Synopsis Cholesterol Clarity by : Jimmy Moore
Download or read book Cholesterol Clarity written by Jimmy Moore and published by Victory Belt Publishing. This book was released on 2013-08-27 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are you confused by what your cholesterol levels really say about your health? Don't you wish someone could just spell it out in simple, easy-to-understand language and tell you what, if anything, you need to do about your cholesterol? Good news! That's precisely what Cholesterol Clarity is designed to do. Jimmy Moore, a prominent and highly respected health blogger and podcaster, has teamed up with Dr. Eric Westman, a practicing internist and nutrition researcher, to bring you one of the most unique books you'll ever read on this subject, featuring exclusive interviews with twenty-nine of the world's top experts from various fields to give you the complete lowdown on cholesterol. If you're worried about any confusing medical jargon in this book, don't be—this critical information is broken down for you to grasp what is really important and what is not. You won't find this kind of comprehensive, cutting-edge, expert-driven cholesterol information all in one place anywhere else. Has your doctor told you your total and/or LDL cholesterol is too high and thus requires you to take immediate action to lower it? Has the solution to your "high cholesterol" been to cut down on your saturated fat intake, eat more "healthy" whole grains and vegetable oils, and possibly even take a prescription medication like a statin to lower it to "desirable" levels? If so, then this is the book for you. Learn what the real deal is from some of the leading experts on the subject. Not only will Cholesterol Clarity tell you what your cholesterol tests—LDL, HDL, triglycerides, and other key cholesterol markers—really mean, but it will also arm you with nutritional guidance that will lead you to optimal health. Are you ready to find out what the HDL is wrong with your numbers?Within the pages of this book you'll learn invaluable lessons, including: • Why your LDL-C and total cholesterol numbers may not be as important in determining your health as your doctor may think-The undeniable negative role that chronic inflammation plays in your health • Why cholesterol-lowering statin drugs don't necessarily solve your heart health concerns • Why your doctor should be testing for LDL particles and particle size when measuring cholesterol • Why HDL and triglycerides are far more predictive of health concerns than LDL-C and total cholesterol • Why consuming foods with saturated fat is good for you, and why carbohydrate-based foods can be detrimental to attaining the best cholesterol numbers • Why a growing number of physicians, researchers, and nutritionists believe treating cholesterol numbers is virtually irrelevant Contributing experts include Cassie Bjork, RD; Philip Blair, MD; Jonny Bowden, PhD; John Briffa, BSc, MB, BS; Dominic D'Agostino, PhD; William Davis, MD; Thomas Dayspring, MD; David Diamond, PhD; Ron Ehrlich, BDS, FACNEM; Jeffry N. Gerber, MD; David Gillespie; Duane Graveline, MD; Paul Jaminet, PhD; Malcolm Kendrick, MD; Ronald Krauss, MD; Fred Kummerow, PhD; Dwight C. Lundell, MD; Robert Lustig, MD; Chris Masterjohn, PhD; Donald Miller, MD; Rakesh "Rocky" Patel, MD; Fred Pescatore, MD; Uffe Ravnskov, MD, PhD; Stephanie Seneff, PhD; Cate Shanahan, MD; Ken Sikaris, BSc, MBBS, FRCPA, FAACB, FFSc; Patty Siri-Tarino, PhD; Mark Sisson; Gary Taubes
