Virulence

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Bacterial Pathogens and Their Virulence Factors

Author : Douglas I. Johnson
Publisher : Springer
ISBN 13 : 3319676512
Total Pages : 451 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Bacterial Pathogens and Their Virulence Factors by : Douglas I. Johnson

Download or read book Bacterial Pathogens and Their Virulence Factors written by Douglas I. Johnson and published by Springer. This book was released on 2017-11-23 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Pathogens and their Virulence Factors contains a detailed description of 32 major bacterial pathogens that affect human health and their associated virulence determinants. Chapter 1 gives an overview of the different types and classes of general virulence factors involved in host cell adherence and invasion, dissemination within the host, host cell damage, and evasion of host defense systems, as well as mechanisms by which these virulence factors are regulated. Chapters 2 through 33 give concise descriptions of the disease states associated with the 32 bacterial genera and their major pathogenic species, along with an in-depth description of the individual virulence factors that have been found to be functionally involved in pathogenicity. A detailed bibliography derived from primary literature and review articles accompanies each of these chapters, allowing the reader to delve more deeply into individual pathogens and their virulence determinants. Chapter 34 discusses the exciting possibilities and initial successes of using detailed information on a pathogen’s virulence toolkit to design new therapeutics aimed at specific virulence traits.

Bacterial Virulence

Author : Anthony William Maresso
Publisher : Springer
ISBN 13 : 9783030204631
Total Pages : 212 pages
Book Rating : 4.2/5 (46 download)

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Book Synopsis Bacterial Virulence by : Anthony William Maresso

Download or read book Bacterial Virulence written by Anthony William Maresso and published by Springer. This book was released on 2019-09-18 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook introduces in an engaging way the fundamentals of how pathogenic bacteria interact with, and are virulent within, the human host. To inspire and educate the next generation of microbe hunters, the author, Microbiologist and Scientist Anthony William Maresso, integrates the major findings of the field into a single, easy-to-understand volume emphasizing a molecular appreciation of the concepts underlying bacterial infectious diseases. The work explores such themes as the history of Microbiology, bacterial structure and physiology, bacterial toxins, secretion systems, and adhesins, the host immune system and its battle with bacteria, biofilms, sepsis, and technologies/techniques to the present day. Fully illustrated in concept and packed with idea-provoking challenges highlighting “out-of-the-box” thinking, the work moves beyond being just a review of the scientific literature intent on equipping the next generation of Microbiologists and their teachers with the knowledge to confront, and hopefully one day defeat, the insidious microbes which undermine human health. This textbook is a resource for undergraduate, graduate, and medical students, as well as other health-oriented learners, postdoctoral scholars, basic scientists, and professors intent on expanding their knowledge of bacterial infection and virulence mechanisms.

Bacterial Pathogenesis

Author :
Publisher : Academic Press
ISBN 13 : 0080860567
Total Pages : 643 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Bacterial Pathogenesis by :

Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. - Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease - Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow - Covers safety aspects, detection, identification and speciation - Includes techniques for the study of host interactions and reactions in animals and plants - Describes biochemical and molecular genetic approaches - Essential methods for gene expression and analysis - Covers strategies and problems for disease control

Implication of Quorum Sensing System in Biofilm Formation and Virulence

Author : Pallaval Veera Bramhachari
Publisher : Springer
ISBN 13 : 9811324298
Total Pages : 377 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Implication of Quorum Sensing System in Biofilm Formation and Virulence by : Pallaval Veera Bramhachari

Download or read book Implication of Quorum Sensing System in Biofilm Formation and Virulence written by Pallaval Veera Bramhachari and published by Springer. This book was released on 2019-01-28 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.

Virulence Mechanisms of Bacterial Pathogens

Author : Indira T. Kudva
Publisher : John Wiley & Sons
ISBN 13 : 1555819281
Total Pages : 871 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Virulence Mechanisms of Bacterial Pathogens by : Indira T. Kudva

Download or read book Virulence Mechanisms of Bacterial Pathogens written by Indira T. Kudva and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ground-breaking overview of an enduring topic Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies. A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including how metabolism shapes the host-pathogen interface interactions across species and genera mechanisms of the secretion systems evasion, survival, and persistence mechanisms new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens Written to promote discussion, extrapolation, exploration, and multidimensional thinking, Virulence Mechanisms of Bacterial Pathogens serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, such as molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, molecular biologists, industry researchers, and technicians.

Classifying Drinking Water Contaminants for Regulatory Consideration

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309171121
Total Pages : 255 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Classifying Drinking Water Contaminants for Regulatory Consideration by : National Research Council

Download or read book Classifying Drinking Water Contaminants for Regulatory Consideration written by National Research Council and published by National Academies Press. This book was released on 2001-08-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Americans drink many gallons of tap water every day, but many of them question the safety of tap water every day as well. In fact, devices have been created to filter tap water directly before reaching cups. It's true; however, that the provision and management of safe drinking water throughout the United States have seen triumphs in public health since the beginning of the 20th century. Although, advances in water treatment, source water protection efforts, and the presence of local, state, and federal regulatory protection have developed over the years, water in the United States still contain chemical, microbiological, and other types of contaminants at detectable and at times harmful levels. This in addition to the growth of microbial pathogens that can resist traditional water treatment practices have led to the question: Where and how should the U.S. government focus its attention and limited resources to ensure safe drinking water supplies for the future? To deal with these issues the Safe Drinking Water Act (SDWA) Amendments of 1996 Safe included a request that the U.S. Environmental Protection Agency (EPA) publish a list of unregulated chemical and microbial contaminants and contaminant groups every five years that are or could pose risks in the drinking water of public water systems. The first list, called the Drinking Water Contaminant Candidate List (CCL), was published in March 1998. The main function of the CCL is to provide the basis for deciding whether to regulate at least five new contaminants from the CCL every five years. However, since additional research and monitoring need to be conducted for most of the contaminants on the 1998 CCL, the list is also used to prioritize these related activities. Classifying Drinking Water Contaminants for Regulatory Consideration is the third report by the Committee on Dinking Water Contaminants with the purpose of providing advice regarding the setting of priorities among drinking water contaminants in order to identify those contaminants that pose the greatest threats to public health. The committee is comprised of 14 volunteer experts in water treatment engineering, toxicology, public health, epidemiology, water and analytical chemistry, risk assessment, risk communication, public water system operations, and microbiology and is jointly overseen by the National Research Council's (NRC'S) Water Science and Technology Board and Board on Environmental Studies and Toxicology. In this report the committee needed to readdress its second report as well as explore the feasibility of developing and using mechanisms for identifying emerging microbial pathogens for research and regulatory activities. The promotion of public health remains the guiding principle of the committee's recommendations and conclusions in this report.

Regulation of Bacterial Virulence

Author : Michael L. Vasil
Publisher : American Society for Microbiology Press
ISBN 13 : 1555816762
Total Pages : 1189 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Regulation of Bacterial Virulence by : Michael L. Vasil

Download or read book Regulation of Bacterial Virulence written by Michael L. Vasil and published by American Society for Microbiology Press. This book was released on 2012-12-05 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch between distinct infectious states (e.g., acute vs. chronic). • Considers key issues about the mechanisms of gene regulation relating to: surface factors, exported toxins and export mechanisms. • Reflects on how the regulation of intracellular lifestyles and the response to stress can ultimately have an impact on the outcome of an infection. • Highlights and examines some emerging regulatory mechanisms of special significance. • Serves as an ideal compendium of valuable topics for students, researchers and faculty with interests in how the mechanisms of gene regulation ultimately affect the outcome of an array of bacterial infectious diseases.

Virulent Zones

Author : Lyle Fearnley
Publisher : Duke University Press
ISBN 13 : 1478012587
Total Pages : 174 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Virulent Zones by : Lyle Fearnley

Download or read book Virulent Zones written by Lyle Fearnley and published by Duke University Press. This book was released on 2020-10-01 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists have identified southern China as a likely epicenter for viral pandemics, a place where new viruses emerge out of intensively farmed landscapes and human--animal interactions. In Virulent Zones, Lyle Fearnley documents the global plans to stop the next influenza pandemic at its source, accompanying virologists and veterinarians as they track lethal viruses to China's largest freshwater lake, Poyang Lake. Revealing how scientific research and expert agency operate outside the laboratory, he shows that the search for origins is less a linear process of discovery than a constant displacement toward new questions about cause and context. As scientists strive to understand the environments from which the influenza virus emerges, the unexpected scale of duck farming systems and unusual practices such as breeding wild geese unsettle research objects, push scientific inquiry in new directions, and throw expert authority into question. Drawing on fieldwork with global health scientists, state-employed veterinarians, and poultry farmers in Beijing and at Poyang Lake, Fearnley situates the production of ecological facts about disease emergence inside the shifting cultural landscapes of agrarian change and the geopolitics of global health.

Principles of Bacterial Pathogenesis

Author : Eduardo A. Groisman
Publisher : Academic Press
ISBN 13 : 0080539580
Total Pages : 863 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Principles of Bacterial Pathogenesis by : Eduardo A. Groisman

Download or read book Principles of Bacterial Pathogenesis written by Eduardo A. Groisman and published by Academic Press. This book was released on 2001-01-09 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants. - Explains the basic principles of bacterial pathogenesis - Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans - Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors - Presents authoritative treatises of the major disease microorganisms

Risk and Technological Culture

Author : Joost Van Loon
Publisher : Routledge
ISBN 13 : 1134584466
Total Pages : 248 pages
Book Rating : 4.1/5 (345 download)

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Book Synopsis Risk and Technological Culture by : Joost Van Loon

Download or read book Risk and Technological Culture written by Joost Van Loon and published by Routledge. This book was released on 2013-01-11 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The question as to whether we are now entering a risk society has become a key debate in contemporary social theory. Risk and Technological Culture presents a critical discussion of the main theories of risk from Ulrich Becks foundational work to that of his contemporaries such as Anthony Giddens and Scott Lash and assesses the extent to which risk has impacted on modern societies. In this discussion van Loon demonstrates how new technologies are transforming the character of risk and examines the relationship between technological culture and society through substantive chapters on topics such as waste, emerging viruses, communication technologies and urban disorders. In so doing this innovative new book extends the debate to encompass theorists such as Bruno Latour, Donna Haraway, Gilles Deleuze, Felix Guattari and Jean-François Lyotard.

Moonlighting Proteins

Author : Brian Henderson
Publisher : John Wiley & Sons
ISBN 13 : 1118951115
Total Pages : 493 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Moonlighting Proteins by : Brian Henderson

Download or read book Moonlighting Proteins written by Brian Henderson and published by John Wiley & Sons. This book was released on 2017-04-17 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science.

Escherichia Coli

Author : Max Sussman
Publisher : Cambridge University Press
ISBN 13 : 9780521453615
Total Pages : 664 pages
Book Rating : 4.4/5 (536 download)

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Book Synopsis Escherichia Coli by : Max Sussman

Download or read book Escherichia Coli written by Max Sussman and published by Cambridge University Press. This book was released on 1997-03-27 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This topical compilation surveys the role of Escherichia coli in health and disease, including food poisoning.

Virulence Mechanisms of Plant-pathogenic Bacteria

Author : Nian Wang
Publisher :
ISBN 13 : 9780890545874
Total Pages : 492 pages
Book Rating : 4.5/5 (458 download)

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Book Synopsis Virulence Mechanisms of Plant-pathogenic Bacteria by : Nian Wang

Download or read book Virulence Mechanisms of Plant-pathogenic Bacteria written by Nian Wang and published by . This book was released on 2015 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

E. coli

Author : Michael Donnenberg
Publisher : Elsevier
ISBN 13 : 0080494811
Total Pages : 453 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis E. coli by : Michael Donnenberg

Download or read book E. coli written by Michael Donnenberg and published by Elsevier. This book was released on 2002-10-09 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research. - Single source of information of E. coli pathogenesis - Expert authors - Comprehensive coverage - Molecular mechanisms - Biology, evolution and genomics - Recent advances

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Concepts in Bacterial Virulence

Author : Wayne Russell
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805577869
Total Pages : 287 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Concepts in Bacterial Virulence by : Wayne Russell

Download or read book Concepts in Bacterial Virulence written by Wayne Russell and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades the increase in bacterial resistance has led to the search for novel antibacterial therapies and a better understanding of virulence mechanisms used by pathogens. It has been shown that the interplay between pathogenic bacteria and the host is complex and finely balanced. Successful pathogens can manipulate host homeostasis and normal cell functions using a variety of molecular strategies. This volume of the Karger book series Contributions to Microbiology summarizes some of the most important bacterial virulence mechanisms. Eminent scientists provide an update on recent findings in their fields. This state-of-the-art account will not only attract the interest of clinical and preclinical researchers, but will also be of great value to students with an interest in medicine, biology, chemistry, and infectious diseases.

Foodborne Pathogens

Author : Joshua B. Gurtler
Publisher : Springer
ISBN 13 : 3319568361
Total Pages : 653 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Foodborne Pathogens by : Joshua B. Gurtler

Download or read book Foodborne Pathogens written by Joshua B. Gurtler and published by Springer. This book was released on 2017-06-14 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne illnesses continue to be a major public health concern. All members of a particular bacterial genera (e.g., Salmonella, Campylobacter) or species (e.g., Listeria monocytogenes, Cronobacter sakazakii) are often treated by public health and regulatory agencies as being equally pathogenic; however, this is not necessarily true and is an overly conservative approach to ensuring the safety of foods. Even within species, virulence factors vary to the point that some isolates may be highly virulent, whereas others may rarely, if ever, cause disease in humans. Hence, many food safety scientists have concluded that a more appropriate characterization of bacterial isolates for public health purposes could be by virotyping, i.e., typing food-associated bacteria on the basis of their virulence factors. The book is divided into two sections. Section I, “Foodborne Pathogens and Virulence Factors,” hones in on specific virulence factors of foodborne pathogens and the role they play in regulatory requirements, recalls, and foodborne illness. The oft-held paradigm that all pathogenic strains are equally virulent is untrue. Thus, we will examine variability in virulence between strains such as Listeria, Salmonella, Campylobacter, Cronobacter, etc. This section also examines known factors capable of inducing greater virulence in foodborne pathogens. Section II, “Foodborne Pathogens, Host Susceptibility, and Infectious Dose” , covers the ability of a pathogen to invade a human host based on numerous extraneous factors relative to the host and the environment. Some of these factors include host age, immune status, genetic makeup, infectious dose, food composition and probiotics. Readers of this book will come away with a better understanding of foodborne bacterial pathogen virulence factors and pathogenicity, and host factors that predict the severity of disease in humans.