Vector control and the elimination of gambiense human African trypanosomiasis (HAT)

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Author :
Publisher : World Health Organization
ISBN 13 : 9240051864
Total Pages : 62 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Vector control and the elimination of gambiense human African trypanosomiasis (HAT) by :

Download or read book Vector control and the elimination of gambiense human African trypanosomiasis (HAT) written by and published by World Health Organization. This book was released on 2022-06-30 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vector control and the elimination of gambiense human African trypanosomiasis (HAT) – Joint FAO/WHO Virtual Expert Meeting, 5-6 October 2021

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Author :
Publisher : Food & Agriculture Org.
ISBN 13 : 9251362505
Total Pages : 62 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Vector control and the elimination of gambiense human African trypanosomiasis (HAT) – Joint FAO/WHO Virtual Expert Meeting, 5-6 October 2021 by : Food and Agriculture Organization of the United Nations

Download or read book Vector control and the elimination of gambiense human African trypanosomiasis (HAT) – Joint FAO/WHO Virtual Expert Meeting, 5-6 October 2021 written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2022-06-14 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human African trypanosomiasis (HAT) is a vector-borne parasitic disease transmitted by tsetse flies in sub-Saharan Africa. The gambiense form of the disease (gHAT) is endemic in western and central Africa and is responsible for more than 95 percent of the HAT cases reported annually. In the road map for neglected tropical diseases 2021–2030, WHO targeted gHAT for elimination of transmission by 2030. FAO supports this goal within the framework of the Programme against African Trypanosomosis (PAAT). In the framework of the WHO network for HAT elimination, FAO and WHO convened a virtual expert meeting to review vector control in the context of gHAT elimination. The experts included health officials from endemic countries and representatives from research and academic institutions, international organizations and the private sector. Seven endemic countries provided reports on recent and ongoing vector control interventions against gHAT at national level (i.e. Angola, Cameroon, Côte d’Ivoire, Chad, Democratic Republic of the Congo, Guinea and Uganda). The country reports were followed by thematic sessions on various aspects of vector control: tools, costs, community-based approaches, monitoring and reporting. Tsetse control was also discussed in the broader framework of One Health, and in particular in relation to the control of animal trypanosomosis. This report presents a summary of the findings and lessons learned.

Control and Surveillance of Human African Trypanosomiasis

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Author :
Publisher : World Health Organization
ISBN 13 : 9241209844
Total Pages : 249 pages
Book Rating : 4.2/5 (412 download)

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Book Synopsis Control and Surveillance of Human African Trypanosomiasis by :

Download or read book Control and Surveillance of Human African Trypanosomiasis written by and published by World Health Organization. This book was released on 2013 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report provides information about new diagnostic approaches, new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease. Human African Tryponosomiasis (HAT) is a disease that afflicts populations in rural Africa, where the tsetse fly vector that transmits the causative trypanosome parasites thrives. There are two forms of HAT: one, known as gambiense HAT, is endemic in West and Central Africa and causes over 95% of current cases; the other, known as rhodesiense HAT, is endemic in East and southern Africa and accounts for the remainder of cases. The presence of parasites in the brain leads to progressive neurological breakdown. Changes to sleep-wake patterns are among the symptoms that characterize the disease, also known as "sleeping sickness". Eventually, patients fall into a coma and die if not treated. Different treatments are available against parasites present in the haemolymphatic system (first stage) and those that have entered the brain (second stage). Currently, lumbar puncture is required to select the appropriate drug.

Human African Trypanosomiasis (Sleeping Sickness)

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Author :
Publisher : MDPI
ISBN 13 : 3039289632
Total Pages : 280 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Human African Trypanosomiasis (Sleeping Sickness) by : Christian Burri

Download or read book Human African Trypanosomiasis (Sleeping Sickness) written by Christian Burri and published by MDPI. This book was released on 2020-06-17 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills, treatment remains error-prone and reports on long-term survivors have emerged, and the relevance of the animal reservoir for T. b. gambiense HAT needs clarification. In addition, to win the “end game” against this massively stigmatized disease, the human factor will play a key role. This Special Issue addresses many of the burning topics about disease elimination in its 12 research and 7 review articles and one case study. The papers critically reflect the approaches used, investigate the mentioned challenges, and propose novel approaches and interventions from various points of view.

Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country

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Author :
Publisher : World Health Organization
ISBN 13 : 9240075550
Total Pages : 44 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country by : World Health Organization

Download or read book Criteria and procedures for the verification of elimination of transmission of T. b. gambiense to the human population in a given country written by World Health Organization and published by World Health Organization. This book was released on 2023-11-06 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Report of the fifth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination, Geneva, Switzerland, 7-9 June 2023

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Author :
Publisher : World Health Organization
ISBN 13 : 9240091238
Total Pages : 111 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Report of the fifth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination, Geneva, Switzerland, 7-9 June 2023 by : World Health Organization

Download or read book Report of the fifth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination, Geneva, Switzerland, 7-9 June 2023 written by World Health Organization and published by World Health Organization. This book was released on 2024-05-03 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concerted efforts by national programmes, supported by public–private partnerships, nongovernmental organizations, donors and academia under the auspices and coordination of the World Health Organization (WHO), have produced important achievements in the control of human African trypanosomiasis (HAT). As a consequence, the disease was targeted for elimination as a public health problem by 2020. The Sixty-sixth World Health Assembly endorsed this goal in resolution WHA66.12 on Neglected tropical diseases, adopted in 2013. National sleeping sickness control programmes (NSSCPs) are core to progressing in the control of the disease and in adapting to the different epidemiological situations. The involvement of different partners, as well as the support and trust of long-term donors, has been crucial for these achievements. More than 20 years of partnership among WHO, Sanofi and Bayer have enabled WHO to strengthen and sustain financial, technical and material support for the implementation of control activities in countries where HAT is endemic. The long-term support from the Government of Belgium, the Bill & Melinda Gates Foundation (BMGF) and other research institutions in the Democratic Republic of the Congo (DRC) has also been essential. WHO convened the fifth stakeholders meeting on the elimination of HAT due to infection with Trypanosoma brucei gambiense (g-HAT) and Trypanosoma brucei rhodesiense (r-HAT) in Geneva, Switzerland, on 7–9 June 2023. The meeting was held again in person after the coronavirus disease (COVID-19) pandemic and jointly for both forms of the disease. The previous meetings on g-HAT held in 2014, 2016 and 2018, as well as on r-HAT in 2015, 2017 and 2019, and jointly for g-HAT and r-HAT in 2021 (8) reinforced the partnership and commitment for HAT elimination and structured the mechanisms of collaboration within the WHO network for HAT elimination. The network includes NSSCPs, groups developing new tools, international and nongovernmental organizations involved in disease control, and donors. Fewer than 1000 cases of HAT annually have been reported over the past 5 years, which is a historic achievement. The area at risk has been substantially reduced. The elimination of HAT as a public health problem at the global level has been achieved. The new road map for neglected tropical diseases (NTDs) 2021−2030 (“the road map”) with the target to interrupt the transmission of g-HAT requires the strengthened and sustained efforts of all stakeholders, national authorities and partners, under WHO coordination. It will take disproportionally high efforts and innovative strategies to find the last cases of g-HAT and neutralize its transmission. Given the limited resources and other competing public health priorities, this is a challenge that requires our joint commitment.

Human African Trypanosomiasis (Sleeping Sickness)

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Author :
Publisher :
ISBN 13 : 9783039289646
Total Pages : 280 pages
Book Rating : 4.2/5 (896 download)

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Book Synopsis Human African Trypanosomiasis (Sleeping Sickness) by : Christian Burri

Download or read book Human African Trypanosomiasis (Sleeping Sickness) written by Christian Burri and published by . This book was released on 2020 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills, treatment remains error-prone and reports on long-term survivors have emerged, and the relevance of the animal reservoir for T. b. gambiense HAT needs clarification. In addition, to win the “end game” against this massively stigmatized disease, the human factor will play a key role. This Special Issue addresses many of the burning topics about disease elimination in its 12 research and 7 review articles and one case study. The papers critically reflect the approaches used, investigate the mentioned challenges, and propose novel approaches and interventions from various points of view.

Control and Surveillance of Human African Trypanosomiasis

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Author :
Publisher :
ISBN 13 :
Total Pages : 237 pages
Book Rating : 4.:/5 (871 download)

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Book Synopsis Control and Surveillance of Human African Trypanosomiasis by :

Download or read book Control and Surveillance of Human African Trypanosomiasis written by and published by . This book was released on 2013 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018

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Author :
Publisher : World Health Organization
ISBN 13 : 9240002294
Total Pages : 74 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018 by :

Download or read book Report of the third WHO stakeholders meeting on gambiense human African trypanosomiasis elimination, Geneva, Switzerland, 18-20 April 2018 written by and published by World Health Organization. This book was released on 2020-03-30 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Report of the fourth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination

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Author :
Publisher : World Health Organization
ISBN 13 : 924004504X
Total Pages : 90 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Report of the fourth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination by :

Download or read book Report of the fourth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination written by and published by World Health Organization. This book was released on 2022-06-06 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Human African Trypanosomiasis, Sleeping Sickness

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 2817808576
Total Pages : 347 pages
Book Rating : 4.8/5 (178 download)

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Book Synopsis Progress in Human African Trypanosomiasis, Sleeping Sickness by : Michel Dumas

Download or read book Progress in Human African Trypanosomiasis, Sleeping Sickness written by Michel Dumas and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human African Trypaniosomiasis (HAT) or sleeping sickness is an old disease to be now considered as reemergent. HAT is endemic in 36 sub-Saharan African countries, in areas where tsetse flies are found. The public health importance of HAT is underestimated, but the disease causes severe social disruption in many rural areas. Along the past fifteen years, numerous studies were made, and now, the mechanisms involved in the disease pathogenesis and in the characteristics of sleep-wake disruption become to be better understood. But, since 50 years, when current drugs were introduced, problems regarding HAT chemotherapy have not been solved. Nevertheless, in-depth studies about trypanosome metabolism have permitted to discover new drug targets. Written by specialists who are very experienced in their respective fields, the contributions provide an indispensable tool for practitioners and scientists.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

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Author :
Publisher : World Health Organization
ISBN 13 : 9241564865
Total Pages : 211 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Investing to Overcome the Global Impact of Neglected Tropical Diseases by : World Health Organization

Download or read book Investing to Overcome the Global Impact of Neglected Tropical Diseases written by World Health Organization and published by World Health Organization. This book was released on 2015-08-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Human Emerging and Re-emerging Infections

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118644646
Total Pages : 2365 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Human Emerging and Re-emerging Infections by : Sunit Kumar Singh

Download or read book Human Emerging and Re-emerging Infections written by Sunit Kumar Singh and published by John Wiley & Sons. This book was released on 2015-11-09 with total page 2365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Toolkit for Integrated Vector Management in Sub-Saharan Africa (A)

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Author :
Publisher : World Health Organization
ISBN 13 : 9241549653
Total Pages : 242 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Toolkit for Integrated Vector Management in Sub-Saharan Africa (A) by : World Health Organization

Download or read book Toolkit for Integrated Vector Management in Sub-Saharan Africa (A) written by World Health Organization and published by World Health Organization. This book was released on 2016-07-27 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. It is an extension of earlier guidance and teaching material published by the World Health Organization (WHO): Handbook for integrated vector management Monitoring and evaluation indicators for integrated vector management Guidance on policy-making for integrated vector management and Core structure for training curricula on integrated vector management. The toolkit provides the technical detail required to plan implement monitor and evaluate an IVM approach. IVM can be used when the aim is to control or eliminate vector-borne diseases and can also contribute to insecticide resistance management. This toolkit provides information on where vector-borne diseases are endemic and what interventions should be used presenting case studies on IVM as well as relevant guidance documents for reference. The diseases that are the focus of this toolkit are malaria lymphatic filariasis dengue leishmaniasis onchocerciasis human African trypanosomiasis and schistosomiasis. It also includes information on other viral diseases (Rift Valley fever West Nile fever Chikungunya yellow fever) and trachoma. If other vector-borne diseases appear in a country or area vector control with an IVM approach should be adopted as per national priorities. Malaria as one of the most important vector-borne diseases in sub-Saharan Africa is the main focus of this document. Programmes targeting other vector-borne diseases can learn from the experiences gained from malaria vector control and presented here.

An Elimination Investment Case (EIC) for Human African Trypanosomiasis (HAT) Trypanosoma Brucei (T.b.) Gambiense ("sleeping Sickness")

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis An Elimination Investment Case (EIC) for Human African Trypanosomiasis (HAT) Trypanosoma Brucei (T.b.) Gambiense ("sleeping Sickness") by : Claudette Simone Sutherland

Download or read book An Elimination Investment Case (EIC) for Human African Trypanosomiasis (HAT) Trypanosoma Brucei (T.b.) Gambiense ("sleeping Sickness") written by Claudette Simone Sutherland and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The African Trypanosomes

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Publisher : Springer Science & Business Media
ISBN 13 : 0306468948
Total Pages : 185 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis The African Trypanosomes by : Samuel J. Black

Download or read book The African Trypanosomes written by Samuel J. Black and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: African trypanosomes are tsetse-transmitted protozoa that inhabit the extracellular compartment of host blood. They cause fatal sleeping sickness in people, and Nagana, a wasting and generally fatal disease, in cattle. While trypanosomes are most common to Africa (about 30% of Africa's cattle graze on the fringe of the tsetse habitat), some species have spread beyond its boarders to Asia, the Middle East and South America. The African Trypanosomes, volume one of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

Traces of the Future

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Author :
Publisher : Intellect (UK)
ISBN 13 : 9781783207251
Total Pages : 0 pages
Book Rating : 4.2/5 (72 download)

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Book Synopsis Traces of the Future by : Wenzel Geissler

Download or read book Traces of the Future written by Wenzel Geissler and published by Intellect (UK). This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a close look at the vestiges of twentieth-century medical work at five key sites in Africa: Senegal, Nigeria, Cameroon, Kenya, and Tanzania. The authors aim to understand the afterlife of scientific institutions and practices and the "aftertime" of scientific modernity and its attendant visions of progress and transformation. Straightforward scholarly work is juxtaposed here with altogether more experimental approaches to fieldwork and analysis, including interview fragments; brief, reflective essays; and a rich photographic archive. The result is an unprecedented view of the lingering traces of medical science from Africa's past.