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Vasopressin And Oxytocin From Genes To Clinical Applications
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Book Synopsis Vasopressin and Oxytocin: From Genes to Clinical Applications by : D. Poulain
Download or read book Vasopressin and Oxytocin: From Genes to Clinical Applications written by D. Poulain and published by Elsevier. This book was released on 2002-10-24 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system. Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.
Book Synopsis Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease by : Rainer Landgraf
Download or read book Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease written by Rainer Landgraf and published by Elsevier. This book was released on 2008-09-10 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohypophysial system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike. Comprehensive review of OXT and AVP physiology and behaviour Each chapter covers a novel aspect of OXT and AVP research and is written by a leading expert Review articles are ideal for experts and newcomers to the field alike Discusses fascinating behavioural effects of oxytocin and vasopressin Summarizes the recent explosion of neuropeptide research, physiology and behaviour, is in one location
Book Synopsis Vasopressin and Oxytocin by : Hans H. Zingg
Download or read book Vasopressin and Oxytocin written by Hans H. Zingg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides a comprehensive overview of recent advances in the field of vasopressin and oxytocin. In the summer of 1997, scientists from over 20 countries congregated in Montreal for the 1997 World Congress of Neurohypophysial Hormones, a conference that united the fields of vasopressin, neurohypophysis and oxytocin in a single joint meeting that gave rise to the present book. The organization of a joint meeting was prompted by several recent developments. Specifically the molecular characterization of the vasopressin/oxytocin receptor family made it mandatory to adopt an integrated view and to discuss the vasopressin/oxytocin ligand/receptor family as a whole. To ensure em phasis on novelty, the conference focused on advances made over the last two years and also included important contributions by scientists that had not previously been associated with the vasopressin/oxytocin field. Vasopressin and oxytocin are two neurohormones that exert a wide spectrum of cen tral and peripheral actions. Accordingly, the vasopressin/oxytocin field embraces a large number of different domains, ranging from neuroscience, endocrinology, and oncology to renal, reproductive, and cardiovascular physiology and pathology.
Book Synopsis Oxytocin's routes in social behavior: into the 21st century. “Precision Medicine” approach for Oxytocin by : Alaine Keebaugh
Download or read book Oxytocin's routes in social behavior: into the 21st century. “Precision Medicine” approach for Oxytocin written by Alaine Keebaugh and published by Frontiers Media SA. This book was released on 2015-12-21 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our brain is endowed with an incredible capacity to be social, to trust, to cooperate, to be altruistic, to feel empathy and love. Nevertheless, the biological underpinnings of such behaviors remain partially hardwired. Seminal research in rodents has provided important insights on the identification of specific genes in modulating social behaviors, in particular, the arginine vasopressin receptor and the oxytocin receptor genes. These genes are involved in regulating a wide range of social behaviors, mother-infant interactions, social recognition, aggression and socio-sexual behavior. Remarkably, we now know that these genes contribute to social behavior in a broad range of species from voles to humans. Indeed, advances in human non-invasive neuroimaging techniques and genetics have enabled scientists to begin to elucidate the neurobiological basis of the complexity of human social behaviors using "pharmacological fMRI" and "imaging genetics". Over the past few years, there has been a strong interest focused on the role of oxytocin in modulating human social behaviors with translational relevance for understanding neuropsychiatric disorders, such as autism, schizophrenia and depression, in which deficits in social perception and social recognition are key phenotypes. The convergence of this interdisciplinary research is beginning to reveal the complex nature of oxytocin’s actions. For instance, the way that oxytocin does influence social functioning is highly related to individual differences in social experiences, but also to the inter-individual variability in the receptor distribution of this molecule in the brain. Remarkably, despite the increasing evidence that oxytocin has a key role in regulating human social behavior, we still lack of knowledge on the core mechanisms of action of this molecule. Understanding its fundamental actions is a crucial need in order to target optimal therapeutic strategies for human social disorders. The originality of this Research Topic stands on its translational focus on bridging the gap between fundamental knowledge acquired from oxytocin research in voles and monkeys and recent clinical investigations in humans. For instance, what are the key animal findings that can import further knowledge on the mechanisms of actions of this molecule in humans? What are the key experiences that can be performed in the animal model in order to answer significant science gaps in the treatment of neuropsychiatric disorders? Hence, within this Research Topic, we will review the current state of the field, identify where the gaps in knowledge are, and propose directions for future research. This issue will begin with a comparative review that examines the role of this peptide in diverse animal models, which highlights the adaptive value of oxytocin’s function across multiple species. Then, a series of reviews will examine the role of oxytocin in voles, primates, and humans with an eye toward revealing commonalities in the underlying brain circuits mediating oxytocin’s effects on social behavior. Next, there will be a translational review highlighting the evidence for oxytocin’s role in clinical applications in psychopathology. Hence, via the continuum of basic to translational research areas, we will try to address the important gaps in our understanding of the neurobiological routes of social cognition and the mechanisms of action of the neuropeptides that guide our behaviors and decisions.
Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Ramon Lim
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Ramon Lim and published by Springer Science & Business Media. This book was released on 2006-09-18 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.
Book Synopsis Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior by : Elena Choleris
Download or read book Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior written by Elena Choleris and published by Cambridge University Press. This book was released on 2013-04-11 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian neurohypophyseal peptide hormones oxytocin and vasopressin act to mediate human social behavior - they affect trust and social relationships and have an influence on avoidance responses. Describing the evolutionary roots of the effects that these neuropeptides have on behavior, this book examines remarkable parallel findings in both humans and non-human animals. The chapters are structured around three key issues: the molecular and neurohormonal mechanisms of peptides; phylogenetic considerations of their role in vertebrates; and their related effects on human behavior, social cognition and clinical applications involving psychiatric disorders such as autism. A final chapter summarizes current research perspectives and reflects on the outlook for future developments. Providing a comparative overview and featuring contributions from leading researchers, this is a valuable resource for graduate students, researchers and clinicians in this rapidly developing field.
Book Synopsis Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior by : Elena Choleris
Download or read book Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior written by Elena Choleris and published by Cambridge University Press. This book was released on 2013-04-11 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian neurohypophyseal peptide hormones oxytocin and vasopressin act to mediate human social behavior - they affect trust and social relationships and have an influence on avoidance responses. Describing the evolutionary roots of the effects that these neuropeptides have on behavior, this book examines remarkable parallel findings in both humans and non-human animals. The chapters are structured around three key issues: the molecular and neurohormonal mechanisms of peptides; phylogenetic considerations of their role in vertebrates; and their related effects on human behavior, social cognition and clinical applications involving psychiatric disorders such as autism. A final chapter summarizes current research perspectives and reflects on the outlook for future developments. Providing a comparative overview and featuring contributions from leading researchers, this is a valuable resource for graduate students, researchers and clinicians in this rapidly developing field.
Book Synopsis Neuropsychiatric Disorders by : Koho Miyoshi
Download or read book Neuropsychiatric Disorders written by Koho Miyoshi and published by Springer Science & Business Media. This book was released on 2010-08-09 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the latest findings in the field and includes chapters on delusional symptoms, mood disorders and neurotic symptoms, cognitive impairment, behavioral and personality changes, and recently, cerebral alterations revealed in PTSD patients and in endogenous psychoses through neuroimaging and neuropathology. These findings will certainly widen the realm of neuropsychiatry going forward and will prove of great value to specialists as well as to academics and trainees in neurology, psychiatry, neuropsychology, neuroradiology, neuropathology, neurophysiology, neurochemistry, and clinical genetics. Ultimately, neuropsychiatry aims to prevent and reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders.
Book Synopsis The Neurohypophysis, Physiological and Clinical Aspects by : Seymour Reichlin
Download or read book The Neurohypophysis, Physiological and Clinical Aspects written by Seymour Reichlin and published by Plenum Publishing Corporation. This book was released on 1984 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Social Hormones and Human Behavior by :
Download or read book Social Hormones and Human Behavior written by and published by . This book was released on 2015 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Origins of the Social Mind by : Bruce J. Ellis
Download or read book Origins of the Social Mind written by Bruce J. Ellis and published by Guilford Press. This book was released on 2005-01-01 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying an evolutionary framework to advance the understanding of child development, this volume brings together leading figures to contribute chapters in their areas of expertise. Researcher- and student-friendly chapters adhere to a common format.
Book Synopsis Clinical Neuroendocrinology by : Michael Wilkinson
Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Book Synopsis Textbook of Endocrine Physiology by : William J. Kovacs
Download or read book Textbook of Endocrine Physiology written by William J. Kovacs and published by OUP USA. This book was released on 2011-11-11 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sixth edition of this highly popular text retains its comprehensive coverage of endocrine basics from previous editions while featuring entirely new chapters on several topics, including the assessment of endocrine function, sexual differentiation, growth regulation, the thyroid, the adrenals, and calcium homeostasis. Chapters have been updated and reorganized to make information easily accessible in concise form, and new figures and tables have been added to enhance the presentation of complex concepts. Fundamental principles of endocrine physiology are reinforced with illustrative examples from clinical observation and the limitations of current knowledge are properly identified. The ideal resource for students entering the field, the Textbook of Endocrine Physiology aims to provide for all a solid basis in fundamentals of endocrinology and for some, inspiration for the pursuit of advanced medical or graduate studies in the field.
Book Synopsis The Neurohypophysis by : William George North
Download or read book The Neurohypophysis written by William George North and published by . This book was released on 1993 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: These conference proceedings on the neurohypophysis, studies central vassopressin-neurons and oxytocin-neurons, and the influence that products of these neurons have on brain function and on the control of homeostasis. Reviews are presented on anatomy and biosynthesis, structure and circuitry, release of neurohypophysial hormones, mechanisms of action and metabolism, physiological actions, influence on behaviour, interactions with the immune system, roles in homeostasis and integration with other hormone systems.
Book Synopsis Social Hormones and Human Behavior: What Do We Know and Where Do We Go from Here by : Idan Shalev
Download or read book Social Hormones and Human Behavior: What Do We Know and Where Do We Go from Here written by Idan Shalev and published by Frontiers Media SA. This book was released on 2015-02-11 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxytocin (OT) and arginine vasopressin (AVP) are the paramount social hormones in mammals and accumulating evidence also strengthens the unique role of these neuropeptides also in human social behavior. Indeed from voles to humans, OT and AVP modulate an intriguing number of social behaviors resonating across species such as the quality of pair bonding, parenting, modulations of social stress, in-group & out-group relationships and social communications. Recent molecular genetic studies of the oxytocin (OXTR), arginine vasopressin 1a (AVPR1a) and arginine vasopressin 1b (AVPR1b) receptors have strengthened the role of these two neuropeptides in a range of normal and pathological human behaviors. Importantly, dysfunctions in the OT and AVP neural pathways are likely contributing to deficits in social skills and communication in disorders such as autism. This Research Topic covers the state of the science and provides a deep view of social hormone research in humans to illustrates how pharmacological, genetic and neuroimaging strategies can be successfully combined toward unraveling the mystery of how human social behavior is regulated. Understanding human social behavior at the molecular level, i.e. social neuroscience, is not only crucial for treatment and diagnosis of disorders characterized by deficits in social cognition but also has important implications in establishing the congruence of findings from different approaches in the Social Sciences and Biology. We bring together in this issue a broad spectrum of investigators from the neurosciences, genetics, psychology, economics and political science towards a deeper understanding of the biological roots of human social behavior. We hope that this transdisciplinary Research Topic will bring new insights and ideas to the field, give future perspectives while also addressing open questions and limitation in order to develop intervention and prevention strategies, and to translate the basic social hormone research into clinical applications. This Research Topic covers the state of the science and provides a deep view of social hormone research in humans to illustrates how pharmacological, genetic and neuroimaging strategies can be successfully combined toward unraveling the mystery of how human social behavior is regulated. Understanding human social behavior at the molecular level, aka social neuroscience, is not only crucial for treatment and diagnosis of disorders characterized by deficits in social cognition but such an understanding has important implications for consilience of the Social Sciences and Biology. We bring together in this issue a broad spectrum of investigators from the neurosciences, genetics, psychology, economics and political science towards a deeper understanding of the biological roots of human social behavior. We hope that this transdisciplinary Research Topic will bring new insights and ideas to the field, give future perspectives while also addressing open questions and limitation in order to develop intervention and prevention strategies, and to translate the basic social hormone research into clinical applications.
Book Synopsis Using Eye Movements as an Experimental Probe of Brain Function by : R. John Leigh
Download or read book Using Eye Movements as an Experimental Probe of Brain Function written by R. John Leigh and published by Elsevier. This book was released on 2008-09-02 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor Professor Jean Büttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological, pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus, and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments for nystagmus and motion sickness. * Clinicians will find important new information on the substrate for spinocerebellar ataxia, late-onset Tay-Sachs disease, Huntington disease, and pulvinar lesions * Organizes multiple articles on such topics as proprioception, short and longer-term memory, and hereditary cerebellar ataxias for a more coherent presentation * Articles on anatomic tracers, functional imaging, and computational neuroscience are illustrated in color
Book Synopsis Serotonin-Dopamine Interaction: Experimental Evidence and Therapeutic Relevance by : Giuseppe Di Giovanni
Download or read book Serotonin-Dopamine Interaction: Experimental Evidence and Therapeutic Relevance written by Giuseppe Di Giovanni and published by Elsevier. This book was released on 2008-09-26 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson’s disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions. Provides an understanding of the interaction between Serotonin and Dopamine Appeals equally to specialists, general practitioners, students and researchers Contributes to the debate on new pharmacological approaches to several psychopathological states Gives a comprehensive anatomical description plus the physiology and pharmacology of dopaminergic and serotonergic systems Singles out neuropsychiatric and suggests new therapeutic approaches
