Author : Rudolf Valenta
Publisher : Springer Science & Business Media
ISBN 13 : 3642200540
Total Pages : 188 pages
Book Rating : 4.6/5 (422 download)
Book Synopsis Vaccines against Allergies by : Rudolf Valenta
Download or read book Vaccines against Allergies written by Rudolf Valenta and published by Springer Science & Business Media. This book was released on 2011-08-26 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are celebrating this year the hundred years ́ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin” by administering increasing doses of grass pollen extract before the grass pollen season to allergic patients. Although it was unknown at that time that allergy represents an immunological hypersensitivity disease, the treatment was effective and many observations made by Noon remained valid until today. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects. In fact, more than 25% of the population suffer from IgE-mediated allergies which therefore represent a major health burden of our society, particularly because untreated allergy often progresses to severe disabling forms of disease, such as asthma and sometimes kills sensitized people through anaphylaxis.