Update On Polymers For Ocular Drug Delivery

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Update on Polymers for Ocular Drug Delivery

Author : Atish S Mundada
Publisher : Smithers Rapra
ISBN 13 : 1847355641
Total Pages : 210 pages
Book Rating : 4.8/5 (473 download)

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Book Synopsis Update on Polymers for Ocular Drug Delivery by : Atish S Mundada

Download or read book Update on Polymers for Ocular Drug Delivery written by Atish S Mundada and published by Smithers Rapra. This book was released on 2011-12-20 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological and anatomical constraints only a small fraction of the drug, effectively 1% or even less of the instilled dose is ocularly absorbed. The effective dose of medication administered ophthalmically may be altered by increasing the retention time of medication in contact with the surface of the eye. To date, Pharmaceutical Technologists have tried to develop different novel formulations like gel, ocular inserts, collagen shields, implants, liposomes, nanoparticles, penetration enhancers and in-situ gelling systems, in order to increase the bioavailability and duration of the therapeutic action of ocular drugs and polymers plays an important role in all these approaches. This book provides detailed information regarding all such polymers which have been used and shown to be excellent in improving the bioavailability of ocular drugs.

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra
Publisher : Elsevier
ISBN 13 : 0128226684
Total Pages : 594 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Applications of Polymers in Drug Delivery by : Ambikanandan Misra

Download or read book Applications of Polymers in Drug Delivery written by Ambikanandan Misra and published by Elsevier. This book was released on 2020-10-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. Explains how polymers can be prepared and utilized for all major drug delivery routes Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Basic Fundamentals of Drug Delivery

Author :
Publisher : Academic Press
ISBN 13 : 0128179104
Total Pages : 810 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Basic Fundamentals of Drug Delivery by :

Download or read book Basic Fundamentals of Drug Delivery written by and published by Academic Press. This book was released on 2018-11-30 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study

Treatise on Ocular Drug Delivery

Author : Ashim K. Mitra
Publisher : Bentham Science Publishers
ISBN 13 : 1608051757
Total Pages : 301 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Treatise on Ocular Drug Delivery by : Ashim K. Mitra

Download or read book Treatise on Ocular Drug Delivery written by Ashim K. Mitra and published by Bentham Science Publishers. This book was released on 2013-06-26 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.

Ocular Drug Delivery: Advances, Challenges and Applications

Author : Richard T. Addo
Publisher : Springer
ISBN 13 : 3319476912
Total Pages : 185 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Ocular Drug Delivery: Advances, Challenges and Applications by : Richard T. Addo

Download or read book Ocular Drug Delivery: Advances, Challenges and Applications written by Richard T. Addo and published by Springer. This book was released on 2016-11-16 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Nano-Biomaterials For Ophthalmic Drug Delivery

Author : Yashwant Pathak
Publisher : Springer
ISBN 13 : 331929346X
Total Pages : 627 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Nano-Biomaterials For Ophthalmic Drug Delivery by : Yashwant Pathak

Download or read book Nano-Biomaterials For Ophthalmic Drug Delivery written by Yashwant Pathak and published by Springer. This book was released on 2016-11-12 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.

Ocular Drug Delivery Systems

Author : Deepak Thassu
Publisher : CRC Press
ISBN 13 : 1439848009
Total Pages : 477 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Ocular Drug Delivery Systems by : Deepak Thassu

Download or read book Ocular Drug Delivery Systems written by Deepak Thassu and published by CRC Press. This book was released on 2012-10-02 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems presents research on the development of currently marketed devices and recent trends in the topical delivery of drugs to the posterior of the eye. With contributions from leading pharmaceutical researchers and industry experts, eye researchers, surgeons, pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis, the book presents the state of the art in the use of nanoparticles in ocular drug delivery systems and also sets the stage for future developments. This volume provides both a current evaluation and a future roadmap for developments in ocular drug delivery. The subjects range from biological needs to material challenges and finally to clinical applications for improving drug delivery for conditions where treatments already exist. It also explores areas where effective drugs may be currently available but yet need a safe, efficient, and efficacious delivery vehicle.

Ophthalmic Drug Delivery

Author : M.F. Saettone
Publisher : Springer Science & Business Media
ISBN 13 : 1475741758
Total Pages : 193 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Ophthalmic Drug Delivery by : M.F. Saettone

Download or read book Ophthalmic Drug Delivery written by M.F. Saettone and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the International Symposium on Ophthalmie Drug Delivery, which was held in Pisa in October 1986. Topical ophthalmic therapy is a matter of interest to specialists from different fields (medical, pharmaceutical, chemical, technological, etc.), who, unfortunately, have a tendency to meet separately, thus limiting a diffusion of knowledge, ideas and experience that would greatly favour the overall pro gress in this area of research. The Symposium, for the first time in Europe, provided the opportunity for specialists from different disciplines and from different countfies to meet, to discuss and to share their experience. This multidisciplinary approach is reflected in the wide variety of topics that appear in the book. The papers are aimed at reviewing many of the complex, interrelated, medical pharmaceutical and technological facets of topical ophthalmic therapy. lt is our hope that they may stimulate further thought in this fascinating field, and may provide possible guidelines for future research. The editors wish to express their appreciation to the sponsors of the Symposium: Fidia Research Laboratories, whose generosity permitted the meeting tobe held, and the ltalian National Research Council (CNR, Progetto Finalizzato Chimica Fine e Secondaria) who gave its scientific tutorship. Thanks are also due to the other Symposium contributors, ACRAF SpA, Rome, and Allergan Italia SpA, Rome. The assistance, support and coopera tion given before, during and after the Symposium by Dr. Patrizia Chetoni, Dr. Maria Tilde Torracca and Dr. Elena Parolini arealso gratefully acknowledged.

Molecularly Imprinted Polymers as Advanced Drug Delivery Systems

Author : Zhaosheng Liu
Publisher : Springer Nature
ISBN 13 : 9811602271
Total Pages : 218 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Molecularly Imprinted Polymers as Advanced Drug Delivery Systems by : Zhaosheng Liu

Download or read book Molecularly Imprinted Polymers as Advanced Drug Delivery Systems written by Zhaosheng Liu and published by Springer Nature. This book was released on 2021-04-23 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1490107959
Total Pages : 1209 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2013 Edition by :

Download or read book Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Molecular Pharmacology. The editors have built Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Pharmacology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Polymeric Drug Delivery Systems

Author : Glen S. Kwon
Publisher : CRC Press
ISBN 13 : 9780824725327
Total Pages : 680 pages
Book Rating : 4.7/5 (253 download)

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Book Synopsis Polymeric Drug Delivery Systems by : Glen S. Kwon

Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Ophthalmic Drug Delivery

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (927 download)

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Book Synopsis Ophthalmic Drug Delivery by :

Download or read book Ophthalmic Drug Delivery written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Smart Polymeric Nano-Constructs in Drug Delivery

Author : Suresh P Vyas
Publisher : Academic Press
ISBN 13 : 0323913997
Total Pages : 626 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Smart Polymeric Nano-Constructs in Drug Delivery by : Suresh P Vyas

Download or read book Smart Polymeric Nano-Constructs in Drug Delivery written by Suresh P Vyas and published by Academic Press. This book was released on 2022-11-12 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. Provides comprehensive overview of the potential role of polymeric systems in drug delivery Explores the design, synthesis, and application of different smart material-based delivery systems Includes fundamental and clinical applications

Update on Polymers for Pulmonary Drug Delivery

Author : Hugh D. C. Smyth
Publisher : Smithers Rapra Technology
ISBN 13 : 9781847356536
Total Pages : 300 pages
Book Rating : 4.3/5 (565 download)

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Book Synopsis Update on Polymers for Pulmonary Drug Delivery by : Hugh D. C. Smyth

Download or read book Update on Polymers for Pulmonary Drug Delivery written by Hugh D. C. Smyth and published by Smithers Rapra Technology. This book was released on 2013-04-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary drug delivery has been a rapidly expanding field, moving from the traditional propellant-based metered-dose inhaler delivery of small asthma drugs, to a broader landscape of new devices and novel drugs for local and systemic delivery. The field has greatly expanded yet the tools for pulmonary drug-delivery systems have not kept pace with the potential applications. One of the key developments has been the use of polymers to achieve better control of pulmonary drug delivery. This has the potential to expand the toolbox available for researchers in the field to deliver their new chemical entities successfully to the lung. This book reviews the use of polymers in pulmonary drug delivery, encompassing polymers from their use in devices and packaging, in addition to their use as excipients in formulations delivered to the airways. The book is arranged by application and extensively reviews the technical and patent literature. This is the first volume totally dedicated to polymers in pulmonary drug delivery and should be the resource of choice for those in the field, especially managers in the pharma/biotech industry. Naturally, the text will be of great interest to academics and graduate students. Finally, regulatory affiliated scientists will also find this resource invaluable.

Ocular Theraputics and Drug Delivery

Author : Indra K. Reddy
Publisher : CRC Press
ISBN 13 : 9781566762137
Total Pages : 618 pages
Book Rating : 4.7/5 (621 download)

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Book Synopsis Ocular Theraputics and Drug Delivery by : Indra K. Reddy

Download or read book Ocular Theraputics and Drug Delivery written by Indra K. Reddy and published by CRC Press. This book was released on 1995-12-12 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since ocular therapeutics and drug delivery is a subject of interest to specialists from various disciplines such as chemical, biochemical, medical, pharmaceutical, and toxicological, it truly presents a unique situation requiring a multi-disciplinary approach in understanding and addressing various problems. Yet we see that scientists associated with these areas are working, by and large, independently of one another, thus limiting dissemination of knowledge, experience and ideas that would greatly enhance the overall progress in this area of research. Regrettably, the information currently available in ocular therapeutics and drug delivery, though extensive, is still fragmented into various disciplines making meaningful synthesis difficult. Several books are available that cover one or two aspects of the multi-disciplinary fields on an individual basis; however, none is available that covers all of them. The chapters contained in this book are specific to various interrelated areas of ocular therapeutics and drug delivery and are written by acknowledged experts from both academia and industry. The book itself is divided into five parts, namely: (I) overview,basic principles, and methodology; (II) pathopharmacology and clinical applications; (III) chemical/ biochemical approaches to ocular drug delivery; (IV) formulation and drug delivery considerations; and (V) industrial and regulatory considerations. Individual chapters in each section, apart from presenting a concise text, entail an extensive listing of references.

Biopharmaceutics of Ocular Drug Delivery

Author : Peter Edman
Publisher : CRC Press
ISBN 13 : 1000693775
Total Pages : 215 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Biopharmaceutics of Ocular Drug Delivery by : Peter Edman

Download or read book Biopharmaceutics of Ocular Drug Delivery written by Peter Edman and published by CRC Press. This book was released on 2019-08-15 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant new book on drug delivery to the eye Biopharmaceutics of Ocular Drug Delivery examines the current physiological, anatomical, pharmaceutical/technological, and biopharmaceutical knowledge on ocular drug delivery. Leading ophthalmic researchers cover topics such as the formulation and usage of ophthalmic solutions and suspensions, the influence of surfactants and preservatives on ocular drug absorption, and new techniques that include bioadhesion and the use of hyaluronic acid as an ophthalmic vehicle. Promising research on new delivery systems for improved drug therapy is highlighted, including new pharmaceutical vehicles, inserts, liposomes, nanoparticles, and prodrugs. Biopharmaceutics of Ocular Drug Delivery is one of the few books available on drug delivery to the eye and will be an important reference for ophthalmologists, pharmacologists, pharmaceutical researchers, and other scientists interested in the topic.

Drug Delivery Nanosystems

Author : Natassa Pippa
Publisher : CRC Press
ISBN 13 : 0429955227
Total Pages : 418 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Drug Delivery Nanosystems by : Natassa Pippa

Download or read book Drug Delivery Nanosystems written by Natassa Pippa and published by CRC Press. This book was released on 2019-01-15 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology seeks to exploit distinct technological advances controlling the structure of nanoscale biomaterials at a nanodimensional scale approaching individual molecules and their aggregates or supramolecular structures. The term "nanomedicine" is used to describe those technologies under the umbrella of nanotechnology that have therapeutic applications in human health. This book presents recent trends and research achievements in the field of pharmaceutical nanotechnology and advanced drug delivery nanosystems, especially for theranostic purposes. The applications of drug delivery nanosystems considered carriers of active pharmaceutical ingredients (APIs) (e.g., proteins, peptides, and nucleic acids) are analyzed on the basis of technology, preparation protocols, and biomedical applications. The book also extensively reports on the principles, design protocols, and applications of nanosystems in drug delivery, imaging, and targeting of active molecules of pharmaceutical interest.