Understanding Bulk Behavior Of Particulate Materials From Particle Scale Simulations

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Understanding Bulk Behavior of Particulate Materials from Particle Scale Simulations

Author : Xiaoliang Deng
Publisher :
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.:/5 (954 download)

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Book Synopsis Understanding Bulk Behavior of Particulate Materials from Particle Scale Simulations by : Xiaoliang Deng

Download or read book Understanding Bulk Behavior of Particulate Materials from Particle Scale Simulations written by Xiaoliang Deng and published by . This book was released on 2016 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particulate materials play an increasingly significant role in various industries, such as pharmaceutical manufacturing, food, mining, and civil engineering. The objective of this research is to better understand bulk behaviors of particulate materials from particle scale simulations. Packing properties of assembly of particles are investigated first, focusing on the effects of particle size, surface energy, and aspect ratio on the coordination number, porosity, and packing structures. The simulation results show that particle sizes, surface energy, and aspect ratio all influence the porosity of packing to various degrees. The heterogeneous force networks within particle assembly under external compressive loading are investigated as well. The results show that coarse-coarse contacts dominate the strong network and coarse-fine contacts dominate the total network. Next, DEM models are developed to simulate the particle dynamics inside a conical screen mill (comil) and magnetically assisted impaction mixer (MAIM), both are important particle processing devices. For comil, the mean residence time (MRT), spatial distribution of particles, along with the collision dynamics between particles as well as particle and vessel geometries are examined as a function of the various operating parameters such as impeller speed, screen hole size, open area, and feed rate. The simulation results can help better understand dry coating experimental results using comil. For MAIM system, the magnetic force is incorporated into the contact model, allowing to describe the interactions between magnets. The simulation results reveal the connections between homogeneity of mixture and particle scale variables such as size of magnets and surface energy of non-magnets. In particular, at the fixed mass ratio of magnets to non-magnets and surface energy the smaller magnets lead to better homogeneity of mixing, which is in good agreement with previously published experimental results. Last but not least, numerical simulations, along with theoretical analysis, are performed to investigate the interparticle force of dry coated particles. A model is derived and can be used to predict the probabilities of hose-host (HH), host-guest (HG), and guest-guest (GG) contacts. The results indicate that there are three different regions dominated by HH, HG, and GG contacts, respectively. Moreover, the critical SAC for the transition of HG to GG contacts is lower than previously estimated value. In summary, particle packing, particle dynamics associated with various particle processing devices, and interparticle force of dry coated particles are investigated in this thesis. The results show that particle scale information such as coordination number, collision dynamics, and contact force between particles from simulation results can help better understand bulk properties of assembly of individual particles.

Blaze-DEM a GPU Based Large Scale 3D Discrete Element Particle Transport Framework

Author : Nicolin Govender
Publisher :
ISBN 13 :
Total Pages : 95 pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis Blaze-DEM a GPU Based Large Scale 3D Discrete Element Particle Transport Framework by : Nicolin Govender

Download or read book Blaze-DEM a GPU Based Large Scale 3D Discrete Element Particle Transport Framework written by Nicolin Govender and published by . This book was released on 2015 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the dynamic behavior of particulate materials is extremely important to many industrial processes with a wide range of applications ranging from hopper flows in agriculture to tumbling mills in the mining industry. Thus simulating the dynamics of particulate materials is critical in the design and optimization of such processes. The mechanical behavior of particulate materials is complex and cannot be described by a closed form solution for more than a few particles. A popular and successful numerical approach in simulating the underlying dynamics of particulate materials is the discrete element method (DEM). However, the DEM is computationally expensive and computationally viable simulations are typically restricted to a few particles with realistic particle shape or a larger number of particles with an often oversimplified particle shape. It has been demonstrated for numerous applications that an accurate representation of the particle shape is essential to accurately capture the macroscopic transport of particulates. The most common approach to represent particle shape is by using a cluster of spheres to approximate the shape of a particle. This approach is computationally intensive as multiple spherical particles are required to represent a single non-spherical particle. In addition spherical particles are for certain applications a poor approximation when sharp interfaces are essential to capture the bulk transport behavior. An advantage of this approach is that non-convex particles are handled with ease. Polyhedra represent the geometry of most convex particulate materials well and when combined with appropriate contact models exhibit realistic transport behavior to that of the actual system. However detecting collisions between the polyhedra is computationally expensive, often limiting simulations to only a few thousand of particles. Driven by the demand for real-time graphics, the Graphical Processor Unit (GPU) offers cluster type performance

Particulate Products

Author : Henk G. Merkus
Publisher : Springer Science & Business Media
ISBN 13 : 3319007149
Total Pages : 479 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Particulate Products by : Henk G. Merkus

Download or read book Particulate Products written by Henk G. Merkus and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particulate products make up around 80% of chemical products, from all industry sectors. Examples given in this book include the construction materials, fine ceramics and concrete; the delicacies, chocolate and ice cream; pharmaceutical, powders, medical inhalers and sun screen; liquid and powder paints. Size distribution and the shape of the particles provide for different functionalities in these products. Some functions are general, others specific. General functions are powder flow and require – at the typical particulate concentrations of these products – that the particles cause adequate rheological behavior during processing and/or for product performance. Therefore, this book addresses particle packing as well as its relation to powder flow and rheological behavior. Moreover, general relationships to particle size are discussed for e.g. color and sensorial aspects of particulate products. Product-specific functionalities are often relevant for comparable product groups. Particle size distribution and shape provide, for example, the following functionalities: - dense particle packing in relation to sufficient strength is required in concrete construction, ceramic objects and pharmaceutical tablets - good sensorial properties (mouthfeel) to chocolate and ice cream - effective dissolution, flow and compression properties for pharmaceutical powders - adequate hiding power and effective coloring of paints for protection and the desired esthetical appeal of the objects - adequate protection of our body against sun light by sunscreen - effective particle transport and deposition to desired locations for medical inhalers and powder paints. Adequate particle size distribution, shape and porosity of particulate products have to be achieved in order to reach optimum product performance. This requires adequate management of design and development as well as sufficient knowledge of the underlying principles of physics and chemistry. Moreover, flammability, explosivity and other health hazards from powders, during handling, are taken into account. This is necessary, since great risks may be involved. In all aspects, the most relevant parameters of the size distribution (and particle shape) have to be selected. In this book, experts in the different product fields have contributed to the product chapters. This provides optimum information on what particulate aspects are most relevant for behavior and performance within specified industrial products and how optimum results can be obtained. It differs from other books in the way that the critical aspects of different products are reported, so that similarities and differences can be identified. We trust that this approach will lead to improved optimization in design, development and quality of many particulate products.

Handbook of Conveying and Handling of Particulate Solids

Author : A. Levy
Publisher : Handbook of Powder Technology
ISBN 13 :
Total Pages : 880 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook of Conveying and Handling of Particulate Solids by : A. Levy

Download or read book Handbook of Conveying and Handling of Particulate Solids written by A. Levy and published by Handbook of Powder Technology. This book was released on 2001 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solids flowability measurement and interpretation in industry / T.A. Bell -- Flow properties of bulk solids : which properties for which application / J. Schwedes -- Investigation on the effect of filling procedures on testing of flow properties by means of a uniaxial tester / G.G. Enstad and K.N. Sjoelyst -- Characterization of powder flow behavior with the flexible wall biaxial tester / R.J.M. Janssen and B. Scarlett -- From discrete element simulations towards a continuum description of particulate solids / S. Luding, M. Lätzel and H.J. Herrmann -- Vibrational flow of cohesive powders / Th. Kollmann and J. Tomas -- Influence of the stress history on the time dependent behaviour of bulk solids / H. Zetzener and J. Schwedes -- Evaluation of the mechanical properties of powder for storage / M. Lubert, A. de Ryck and J.A. Dodds -- Particle adhesion and powder flow behaviour / J. Tomas -- Determination of the influence of surface coating and particle size on flow properties of organic pi ...

Particle Technology and Engineering

Author : Jonathan P.K. Seville
Publisher : Butterworth-Heinemann
ISBN 13 : 0080983448
Total Pages : 296 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Particle Technology and Engineering by : Jonathan P.K. Seville

Download or read book Particle Technology and Engineering written by Jonathan P.K. Seville and published by Butterworth-Heinemann. This book was released on 2016-05-20 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particle Technology and Engineering presents the basic knowledge and fundamental concepts that are needed by engineers dealing with particles and powders. The book provides a comprehensive reference and introduction to the topic, ranging from single particle characterization to bulk powder properties, from particle-particle interaction to particle-fluid interaction, from fundamental mechanics to advanced computational mechanics for particle and powder systems. The content focuses on fundamental concepts, mechanistic analysis and computational approaches. The first six chapters present basic information on properties of single particles and powder systems and their characterisation (covering the fundamental characteristics of bulk solids (powders) and building an understanding of density, surface area, porosity, and flow), as well as particle-fluid interactions, gas-solid and liquid-solid systems, with applications in fluidization and pneumatic conveying. The last four chapters have an emphasis on the mechanics of particle and powder systems, including the mechanical behaviour of powder systems during storage and flow, contact mechanics of particles, discrete element methods for modelling particle systems, and finite element methods for analysing powder systems. This thorough guide is beneficial to undergraduates in chemical and other types of engineering, to chemical and process engineers in industry, and early stage researchers. It also provides a reference to experienced researchers on mathematical and mechanistic analysis of particulate systems, and on advanced computational methods. - Provides a simple introduction to core topics in particle technology: characterisation of particles and powders: interaction between particles, gases and liquids; and some useful examples of gas-solid and liquid-solid systems - Introduces the principles and applications of two useful computational approaches: discrete element modelling and finite element modelling - Enables engineers to build their knowledge and skills and to enhance their mechanistic understanding of particulate systems

Numerical Simulations of Granular Flow and Filling

Author : Claas Sven Bierwisch
Publisher :
ISBN 13 : 9783832283384
Total Pages : 144 pages
Book Rating : 4.2/5 (833 download)

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Book Synopsis Numerical Simulations of Granular Flow and Filling by : Claas Sven Bierwisch

Download or read book Numerical Simulations of Granular Flow and Filling written by Claas Sven Bierwisch and published by . This book was released on 2009 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Particle Technology

Author : Martin J. Rhodes
Publisher : John Wiley & Sons
ISBN 13 : 1119931169
Total Pages : 501 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Introduction to Particle Technology by : Martin J. Rhodes

Download or read book Introduction to Particle Technology written by Martin J. Rhodes and published by John Wiley & Sons. This book was released on 2024-05-16 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: INTRODUCTION TO PARTICLE TECHNOLOGY A new edition of the indispensable guide to particulates and powders Particle technology concerns the formation, processing and properties of the particles and powders which make up many of the products that surround us. Such products range from the cement and aggregate in the built environment to pharmaceuticals and processed foods. Most of the process industries involve particles, either as essential components such as catalysts or as intermediate or final products, and minerals such as the rare earths that are generally mined and processed in particulate form. Particles can have many beneficial uses but they can also cause harm in the environment and, through inhalation, to the individual. In all cases, the powder properties, particularly particle size, are crucially important. This well-known textbook, now in its 3rd edition, provides an easily-understood introduction to the underlying scientific principles of particle technology, together with examples of how these principles can be used in practical design and operation of industrial processes. Each chapter contains both worked examples and exercises for the student. Based on feedback from students and users of the earlier editions, this revised and expanded text includes introductory chapters on particles as products and on computational methods. The topics have been selected to give coverage of the broad areas of particle technology and include: Characterization (size analysis, surface area) Processing (granulation, fluidization) Particle formation (granulation, crystallisation, tableting, size reduction) Storage and transport (hopper design, pneumatic conveying, standpipes) Separation (filtration, settling, cyclones) Safety (fire and explosion hazards, health hazards) Engineering the properties of particulate systems to achieve desired product performance Discrete element modelling of particulate systems Introduction to Particle Technology, 3rd Edition is essential reading for students of chemical engineering. The text is also recommended reading for students of mechanical engineering, applied chemistry, pharmaceutics, physics, mineral processing, and metallurgy, and is an excellent source for practising engineers and scientists looking to establish a working knowledge of the subject.

Proceedings of the 8th International Conference on Foundations of Computer-Aided Process Design

Author :
Publisher : Elsevier
ISBN 13 : 0444634428
Total Pages : 835 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Proceedings of the 8th International Conference on Foundations of Computer-Aided Process Design by :

Download or read book Proceedings of the 8th International Conference on Foundations of Computer-Aided Process Design written by and published by Elsevier. This book was released on 2014-07-14 with total page 835 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects together the presentations at the Eighth International Conference on Foundations of Computer-Aided Process Design, FOCAPD-2014, an event that brings together researchers, educators, and practitioners to identify new challenges and opportunities for process and product design. The chemical industry is currently entering a new phase of rapid evolution. The availability of low-cost feedstocks from natural gas is causing renewed investment in basic chemicals in the OECD, while societal pressures for sustainability and energy security continue to be key drivers in technology development and product selection. This dynamic environment creates opportunities to launch new products and processes and to demonstrate new methodologies for innovation, synthesis and design. FOCAPD-2014 fosters constructive interaction among thought leaders from academia, industry, and government and provides a showcase for the latest research in product and process design. - Focuses exclusively on the fundamentals and applications of computer-aided design for the process industries. - Provides a fully archival and indexed record of the FOCAPD14 conference - Aligns the FOCAPD series with the ESCAPE and PSE series

Dynamic Behavior of Materials, Volume 1

Author : Bo Song
Publisher : Springer Science & Business Media
ISBN 13 : 3319007718
Total Pages : 477 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Dynamic Behavior of Materials, Volume 1 by : Bo Song

Download or read book Dynamic Behavior of Materials, Volume 1 written by Bo Song and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamic Behavior of Materials, Volume 1: Proceedings of the 2013 Annual Conference on Experimental and Applied Mechanics, the first volume of eight from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Experimental Mechanics, including papers on: General Dynamic Material Properties Novel Dynamic Testing Techniques Dynamic Fracture and Failure Novel Testing Techniques Dynamic Behavior of Geo-materials Dynamic Behavior of Biological and Biomimetic Materials Dynamic Behavior of Composites and Multifunctional Materials Dynamic Behavior of Low-Impedance materials Multi-scale Modeling of Dynamic Behavior of Materials Quantitative Visualization of Dynamic Behavior of Materials Shock/Blast Loading of Materials

Production, Handling and Characterization of Particulate Materials

Author : Henk G. Merkus
Publisher : Springer
ISBN 13 : 3319209493
Total Pages : 557 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Production, Handling and Characterization of Particulate Materials by : Henk G. Merkus

Download or read book Production, Handling and Characterization of Particulate Materials written by Henk G. Merkus and published by Springer. This book was released on 2015-11-26 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents most techniques and methods that have been developed by material scientists, chemists, chemical engineers and physicists for the commercial production of particulate materials, ranging from the millimeter to the nanometer scale. The scope includes the physical and chemical background, experimental optimization of equipment and procedures, as well as an outlook on future methods. The books addresses issues of industrial importance such as specifications, control parameter(s), control strategy, process models, energy consumption and discusses the various techniques in relation to potential applications. In addition to the production processes, all major unit operations and characterization methods are described in this book. It differs from other books which are devoted to a single technique or a single material. Contributors to this book are acknowledged experts in their field. The aim of the book is to facilitate comparison of the different unit operations leading to optimum equipment choices for the production, handling and storage of particulate materials. An advantage of this approach is that unit operations that are common in one field of application are made accessible to other fields. The overall focus is on industrial application and the book includes some concrete examples. The book is an essential resource for students or researchers who work in collaboration with manufacturing industries or who are planning to make the switch from academia to industry.

Particulate Materials

Author : Chuan-Yu Wu
Publisher : Royal Society of Chemistry
ISBN 13 : 184973366X
Total Pages : 305 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Particulate Materials by : Chuan-Yu Wu

Download or read book Particulate Materials written by Chuan-Yu Wu and published by Royal Society of Chemistry. This book was released on 2012 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Naturally occurring or manufactured through chemical and/or physical processes, particulate materials are substances consisting of individual particles which have significance to the global economy, society and environments. Due to the diversity and intrinsic nature, manufacturing, handling and processing of particulate materials still face numerous challenges. Aimed at addressing these challenges, this book contains a selection of papers discussing the state-of-the-art research in particulate materials science that were presented at the UK-China Particle Technology Forum III held at Birmingham, UK in 2011. Classified into four distinct topics namely synthesis, characterisation, processing and modelling, the chapters showcase the advances in these areas including a range of advanced synthesis methods for example, spray-pyrolysis, supercritical fluid synthesis assisted with ultrasound, continuous synthesis using supercritical water, hydrothermal synthesis of nano-particulate materials and jet milling. For characterisation, various methods for characterising particulate materials at both particle and system levels are introduced and how these properties affect the behaviour of particulate materials in various processes, such as inhalation, filling, and consolidation, are discussed. In the processing section, recent advances such as capsule filling, micro-dosing, dry granulation, roll compaction, milling, and more are presented. The last section concerns mathematical and numerical modelling in particulate materials, for which the book includes both analytical methods and advanced numerical methods, such as discrete element methods (DEM), computational fluid dynamics (CFD), lattice Boltzmann methods (LBM), coupled DEM/CFD and DEM/LBM, and their applications. Particulate Materials is aimed at research communities dealing with these diverse materials, and scientists and engineers in powder handling industries, such as pharmaceutical, food, fine chemical and detergents.

Understanding Particle-level Physics to Describe the Bulk Compaction Response of Particulate Materials

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (967 download)

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Book Synopsis Understanding Particle-level Physics to Describe the Bulk Compaction Response of Particulate Materials by :

Download or read book Understanding Particle-level Physics to Describe the Bulk Compaction Response of Particulate Materials written by and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Processing of Particulate Solids

Author : J.P. Seville
Publisher : Springer Science & Business Media
ISBN 13 : 9400914598
Total Pages : 384 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Processing of Particulate Solids by : J.P. Seville

Download or read book Processing of Particulate Solids written by J.P. Seville and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over half of the products of the chemical and process industries are sold in a particulate form. The range of such products is vast: from agrochemicals to pigments, from detergents to foods, from plastics to pharmaceuticals. However, surveys of the performance of processes designed to produce particulate products have consistently shown inadequate design and poor reliability. `Particle technology' is a new subject facing new challenges. Chemical and process engineering is becoming less concerned with the design of plants to produce generic simple chemicals (which are often single phase fluids) and is now more concerned with speciality `effect' chemicals which may often be in particulate form. Chemical and process engineers are also being recruited in increasing numbers into areas outside their tranditional fields, such as the food industry, pharmaceuticals and the manufacture of a wide variety of consumer products. This book has been written to meet their needs. It provides comprehensive coverage of the technology of particulate solids, in a form which is both accessible and concise enough to be useful to engineering and science students in the final year of an undergraduate degree, and at Master's level. Although it was written with students of chemical engineering in mind, it will also be of use and interest to students of other disciplines. It comprises an account of the fundamentals of teh subject, illustrated by worked examples, and followed by a wide range of selected applications.

Effect of Particle Properties on Bulk Solids Behaviour

Author : Mohammed Rowshanfekr-Fallah
Publisher :
ISBN 13 :
Total Pages : 139 pages
Book Rating : 4.:/5 (117 download)

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Book Synopsis Effect of Particle Properties on Bulk Solids Behaviour by : Mohammed Rowshanfekr-Fallah

Download or read book Effect of Particle Properties on Bulk Solids Behaviour written by Mohammed Rowshanfekr-Fallah and published by . This book was released on 1981 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the work was to investigate the effect of the size and shape of individual particles on the bulk failure properties of particulate materials, as characterised by the effective angle of internal friction and the angle of friction on a mild steel plate, using a Jenike flow factor tester. The materials used were: (a) Three types of sand of different particle shape, each being sieved into six size fractions; (b) Four types of plastic cylinders of different L/D ratios;(c) Crushed polystyrene. sieved into five size fractions;(d) Polystyrene cylinders coated with crushed polystyrene of three different sizes, to produce particles of different roughness.

Mechanics of Particulate Materials

Author : J. Feda
Publisher : Elsevier
ISBN 13 : 0444600841
Total Pages : 448 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Mechanics of Particulate Materials by : J. Feda

Download or read book Mechanics of Particulate Materials written by J. Feda and published by Elsevier. This book was released on 2013-11-11 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanics of Particulate Materials

Discrete Element Methods

Author : Benjamin K. Cook
Publisher :
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Discrete Element Methods by : Benjamin K. Cook

Download or read book Discrete Element Methods written by Benjamin K. Cook and published by . This book was released on 2002 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Third International Conference on Discrete Element Methods, held in Santa Fe, New Mexico on September 23-25, 2002. This Geotechnical Special Publication contains 72 technical papers on discrete element methods (DEM), a suite of numerical techniques developed to model granular materials, rock, and other discontinua at the grain scale. Topics include: DEM formulation and implementation approaches, coupled methods, experimental validation, and techniques, including three-dimensional particle representations, efficient contact detection algorithms, particle packing schemes, and code design. Coupled methods include approaches to linking solid continuum and fluid models with DEM to simulate multiscale and multiphase phenomena. Applications include fundamental investigations of granular mechanics; micromechanical studies of powder, soil, and rock behavior; and large-scale modeling of geotechnical, material processing, mining, and petroleum engineering problems.

Chemical Engineering in the Pharmaceutical Industry

Author : Mary T. am Ende
Publisher : John Wiley & Sons
ISBN 13 : 1119285496
Total Pages : 690 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : Mary T. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende and published by John Wiley & Sons. This book was released on 2019-04-09 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.