Truly Non Invasive Glucose Optical Sensor Based On Metal Nanoparticles Generation

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Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation

Author : Marisol Garcia
Publisher :
ISBN 13 :
Total Pages : 41 pages
Book Rating : 4.:/5 (979 download)

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Book Synopsis Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation by : Marisol Garcia

Download or read book Truly Non Invasive Glucose Optical Sensor Based on Metal Nanoparticles Generation written by Marisol Garcia and published by . This book was released on 2006 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a disease that causes many complications in human normal function. This disease represents the sixth-leading cause of death in USA. Prevention of diabetes-related complications can be accomplished through tight control of glucose levels in blood. In the last decades many different glucose sensors have been developed, however, none of them are really non invasive. Herein, we present the study of the application of gold and silver nanoparticles with different shapes and aspect ratios to detect glucose traces in human fluids such as tears and sweat. This is to our knowledge the first truly non invasive glucose optical sensor, with extraordinary limit of detection and selectivity. The best proven nanoparticles for this application were gold nanospheres. Gold nanospheres were synthesized using chloroauric acid tri-hydrated (HAuCl4.3H2O) in solution, in the presence of glucose and ammonia hydroxide. The higher the glucose concentration, the higher the number of nanoparticles generated, thus the higher the extinction efficiency of the solution. The linear dependence of the extinction efficiency of the gold nanoparticles solution with glucose concentration makes of this new sensor suitable for direct applications in biomedical sensing. Our approach is based on the well known Tollens test.

Glucose Level Estimation Based on Invasive Electrochemical, and Non-invasive Optical Sensing Methods

Author : Sanghamitra Mandal
Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (19 download)

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Book Synopsis Glucose Level Estimation Based on Invasive Electrochemical, and Non-invasive Optical Sensing Methods by : Sanghamitra Mandal

Download or read book Glucose Level Estimation Based on Invasive Electrochemical, and Non-invasive Optical Sensing Methods written by Sanghamitra Mandal and published by . This book was released on 2018 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this research is to design and fabricate sensors for glucose detection using inexpensive approaches. My first research approach is the fabrication of an amperometric electrochemical glucose sensor, by exploiting the optical properties of semiconductors and structural properties of nanostructures, to enhance the sensor sensitivity and response time. Enzymatic electrochemical sensors are fabricated using two different mechanisms: (1) the low-temperature hydrothermal synthesis of zinc oxide nanorods, and (2) the rapid metal-assisted chemical etching of silicon (Si) to synthesize Si nanowires. The concept of gold nano-electrode ensembles is then employed to the sensors in order to boost the current sensitivities by enhancing the rate of electron transfer during the electrochemical reaction. High crystallinity and good alignment of the nanostructures lead to increase in the electrode surface area, thereby leading to higher current sensitivities compared to other published works. My second research approach is to design an optical sensor for evaluating long-term glycemic state in diabetic patients. Glycated hemoglobin (HbA1c) is a minor component of blood hemoglobin to which glucose is bound. The HbA1c test is a common medical test used to indicate the average blood glucose level over the past 12-16 weeks. The National Institute of Diabetes and Digestive and Kidney Diseases has established a direct relationship between the percentage of HbA1c and the blood sugar level. Our sensor instrumentation design is based on the Beer's law of optical absorption. Major device components include two commercial light emitting diodes, a cuvette holder, a Si photodiode, and an ATmega328P microcontroller. It is observed that the absorbance of diluted HbA1c samples and the corresponding photodiode output voltage are inversely related. The photodiode voltages as a function of HbA1c percentage concentrations show an exponentially decaying curve. An algorithm for multiple variable regression analysis is then used for sensor calibration. The percentage of HbA1c is then anticipated based on the obtained output voltage using the calibrated curve results. The proposed portable optical sensor proves to be a promising step towards the prediction of the long-term glycemic levels in diabetic and pre-diabetic patients non-invasively.

Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues

Author : Valery V. Tuchin
Publisher : CRC Press
ISBN 13 : 9781584889755
Total Pages : 744 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues by : Valery V. Tuchin

Download or read book Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues written by Valery V. Tuchin and published by CRC Press. This book was released on 2008-12-22 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although noninvasive, continuous monitoring of glucose concentration in blood and tissues is one of the most challenging areas in medicine, a wide range of optical techniques has recently been designed to help develop robust noninvasive methods for glucose sensing. For the first time in book form, the Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues analyzes trends in noninvasive optical glucose sensing and discusses its impact on tissue optical properties. This handbook presents methods that improve the accuracy in glucose prediction based on infrared absorption spectroscopy, recent studies on the influence of acute hyperglycemia on cerebral blood flow, and the correlation between diabetes and the thermo-optical response of human skin. It examines skin glucose monitoring by near-infrared spectroscopy (NIR), fluorescence-based glucose biosensors, and a photonic crystal contact lens sensor. The contributors also explore problems of polarimetric glucose sensing in transparent and turbid tissues as well as offer a high-resolution optical technique for noninvasive, continuous, and accurate blood glucose monitoring and glucose diffusion measurement. Written by world-renowned experts in biomedical optics and biophotonics, this book gives a complete, state-of-the-art treatise on the design and applications of noninvasive optical methods and instruments for glucose sensing.

Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions

Author : Carlos G. Juan
Publisher : Springer Nature
ISBN 13 : 3030761797
Total Pages : 256 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions by : Carlos G. Juan

Download or read book Designing Microwave Sensors for Glucose Concentration Detection in Aqueous and Biological Solutions written by Carlos G. Juan and published by Springer Nature. This book was released on 2021-06-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive study covering the design and application of microwave sensors for glucose concentration detection, with a special focus on glucose concentration tracking in watery and biological solutions. This book is based on the idea that changes in the glucose concentration provoke variations in the dielectric permittivity of the medium. Sensors whose electrical response is sensitive to the dielectric permittivity of the surrounding media should be able to perform as glucose concentration trackers. At first, this book offers an in-depth study of the dielectric permittivity of water–glucose solutions at concentrations relevant for diabetes purposes; in turn, it presents guidelines for designing suitable microwave resonators, which are then tested in both water–glucose solutions and multi-component human blood plasma solutions for their detection ability and sensitivities. Finally, a portable version is developed and tested on a large number of individuals in a real clinical scenario. All in all, the book reports on a comprehensive study on glucose monitoring devices based on microwave sensors. It covers in depth the theoretical background, provides extensive design guidelines to maximize sensitivity, and validates a portable device for applications in clinical settings.

NASCENT MEMS AND NANOTECHNOLOGY BASED HARDWARE TECHNOLOGIES FOR NEXT-GENERATION GLUCOSE SENSING AND INSULIN PUMPING

Author : Sumita Pennathur
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis NASCENT MEMS AND NANOTECHNOLOGY BASED HARDWARE TECHNOLOGIES FOR NEXT-GENERATION GLUCOSE SENSING AND INSULIN PUMPING by : Sumita Pennathur

Download or read book NASCENT MEMS AND NANOTECHNOLOGY BASED HARDWARE TECHNOLOGIES FOR NEXT-GENERATION GLUCOSE SENSING AND INSULIN PUMPING written by Sumita Pennathur and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite considerable technical advances, there remains a dearth of minimally invasive glucose sensing and insulin delivery devices that are accurate, sleek, user-friendly, and transformative enough to revolutionize diabetes management. Coming from mechanical engineering, and more specifically, nanotechnology, I have spent the last three years -- since my daughter was diagnosed with Type I diabetes u2013 using the latest advancements in microelectromechanical systems (MEMS), nanotechnology, and electrokinetic micro- and nano-fluidics to invent diabetes technologies which meet these requirements.We have recently made three major breakthroughs to enable fluid sampling, glucose sensing, and insulin delivery in small, low-power, on-body devices. Firstly, we have developed innovative microneedle fabrication technologies which overcome the major limitations of existing needles. Our fabrication strategy produces repeatable, reliable needle arrays with the requisite hollowed bellowed tip required for painless insertion. Secondly, we have invented a stable, non-enzymatic optical glucose sensing platform. We recently developed a dual junction photodiode within a silicon MEMS substrate which can be integrated with commercially available LEDs into a single on-body, fluorescent-based glucose sensing device. Thirdly, we have harnessed a decade of nanofluidic electrokinetic research to develop an insulin delivery strategy that can enable a sleek, thin, fluidic patch pump. Specifically, we use bipolar electrodes to create concentration gradients in ionic fluids sufficient to create pressures for continuous, harmless electrokinetic based pumping. We are now developing these technologies to enable painless, minimally invasive, small form-factor CGM and micropump devices which, coupled with existing algorithms, could revolutionize glucose management.

A Preliminary Study of a Non-invasive Glucose Sensor Based on a Mercury Sensor

Author : Erin Leigh Wood
Publisher :
ISBN 13 :
Total Pages : 37 pages
Book Rating : 4.:/5 (554 download)

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Book Synopsis A Preliminary Study of a Non-invasive Glucose Sensor Based on a Mercury Sensor by : Erin Leigh Wood

Download or read book A Preliminary Study of a Non-invasive Glucose Sensor Based on a Mercury Sensor written by Erin Leigh Wood and published by . This book was released on 2009 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a potentially lethal disease that affects 7.6 percent of American people. In the US, it is recognized as the 6th leading cause of death. Failure to control blood glucose levels (BGL) in patients with either type of diabetes can lead to other serious complications as well, such as loss of limb, blindness and other health problems. Controlling and monitoring the BGL in post-op and intensive care patients in the hospital is also vital to their health. Currently the most reliable method of monitoring BGL is through an invasive procedure which monitors the amount of glucose in blood directly. A non-invasive glucose sensor would drastically improve the treatment of sensitive patients, and serve to improve the quality of diabetic patients' lives. This glucose sensor is strongly based upon the mercury sensor developed by F.E. Hernandez and his colleagues. Glucose is used as a reducing agent to reduce mercury from Hg2+ to Hg0, which will form amalgams with the gold nanorods in solution. The change in aspect ratio of gold nanorods leads to a change in the UV-Visible spectrum of the solution. The blue shift seen was measured and correlated with the glucose concentration of the system. The system was then tested varying conditions such as pH, temperature, gold nanorod concentration, and mercury concentration. A preliminary study of the kinetics of the reaction was also done. The results showed a limit of detection of 1.58x10−13 and a linear dynamic range covering the concentrations of human tear glucose levels that are currently cited in the literature.

Glucose Sensing

Author : Chris D. Geddes
Publisher : Springer Science & Business Media
ISBN 13 : 0387330151
Total Pages : 460 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Glucose Sensing by : Chris D. Geddes

Download or read book Glucose Sensing written by Chris D. Geddes and published by Springer Science & Business Media. This book was released on 2007-12-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.

Glucose Sensing

Author : Chris D. Geddes
Publisher : Springer
ISBN 13 : 9781489993441
Total Pages : 0 pages
Book Rating : 4.9/5 (934 download)

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Book Synopsis Glucose Sensing by : Chris D. Geddes

Download or read book Glucose Sensing written by Chris D. Geddes and published by Springer. This book was released on 2014-12-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.

In Vivo Glucose Sensing

Author : David D. Cunningham
Publisher : John Wiley & Sons
ISBN 13 : 0470567309
Total Pages : 466 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis In Vivo Glucose Sensing by : David D. Cunningham

Download or read book In Vivo Glucose Sensing written by David D. Cunningham and published by John Wiley & Sons. This book was released on 2009-11-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. It focuses on analyzing samples in the real world and discusses the biological complexities that make glucose sensing difficult. Covering current implantable devices, next-generation implantable sensing methods, and non-invasive methods for measuring glucose, this book concludes with an overview of possible applications other than diabetes.

Metal Nanoparticles in Microbiology

Author : Mahendra Rai
Publisher : Springer Science & Business Media
ISBN 13 : 3642183123
Total Pages : 306 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Metal Nanoparticles in Microbiology by : Mahendra Rai

Download or read book Metal Nanoparticles in Microbiology written by Mahendra Rai and published by Springer Science & Business Media. This book was released on 2011-04-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.

Glucose Monitoring Devices

Author : Chiara Fabris
Publisher : Academic Press
ISBN 13 : 0128168846
Total Pages : 386 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Glucose Monitoring Devices by : Chiara Fabris

Download or read book Glucose Monitoring Devices written by Chiara Fabris and published by Academic Press. This book was released on 2020-06-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glucose Monitoring Devices: Measuring Blood Glucose to Manage and Control Diabetes presents the state-of-the-art regarding glucose monitoring devices and the clinical use of monitoring data for the improvement of diabetes management and control. Chapters cover the two most common approaches to glucose monitoring–self-monitoring blood glucose and continuous glucose monitoring–discussing their components, accuracy, the impact of use on quality of glycemic control as documented by landmark clinical trials, and mathematical approaches. Other sections cover how data obtained from these monitoring devices is deployed within diabetes management systems and new approaches to glucose monitoring. This book provides a comprehensive treatment on glucose monitoring devices not otherwise found in a single manuscript. Its comprehensive variety of topics makes it an excellent reference book for doctoral and postdoctoral students working in the field of diabetes technology, both in academia and industry. Presents a comprehensive approach that spans self-monitoring blood glucose devices, the use of continuous monitoring in the artificial pancreas, and intraperitoneal glucose sensing Provides a high-level descriptions of devices, as well as detailed mathematical descriptions of methods and techniques Written by experts in the field with vast experience in the field of diabetes and diabetes technology

Wearable Bioelectronics

Author : Anthony P.F. Turner
Publisher : Elsevier
ISBN 13 : 0081024088
Total Pages : 240 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Wearable Bioelectronics by : Anthony P.F. Turner

Download or read book Wearable Bioelectronics written by Anthony P.F. Turner and published by Elsevier. This book was released on 2019-11-26 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wearable Bioelectronics presents the latest on physical and (bio)chemical sensing for wearable electronics. It covers the miniaturization of bioelectrodes and high-throughput biosensing platforms while also presenting a systemic approach for the development of electrochemical biosensors and bioelectronics for biomedical applications. The book addresses the fundamentals, materials, processes and devices for wearable bioelectronics, showcasing key applications, including device fabrication, manufacturing, and healthcare applications. Topics covered include self-powering wearable bioelectronics, electrochemical transducers, textile-based biosensors, epidermal electronics and other exciting applications. - Includes comprehensive and systematic coverage of the most exciting and promising bioelectronics, processes for their fabrication, and their applications in healthcare - Reviews innovative applications, such as self-powering wearable bioelectronics, electrochemical transducers, textile-based biosensors and electronic skin - Examines and discusses the future of wearable bioelectronics - Addresses the wearable electronics market as a development of the healthcare industry

Nanotechnology-Enabled Sensors

Author : Kourosh Kalantar-zadeh
Publisher : Springer Science & Business Media
ISBN 13 : 0387680233
Total Pages : 502 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Nanotechnology-Enabled Sensors by : Kourosh Kalantar-zadeh

Download or read book Nanotechnology-Enabled Sensors written by Kourosh Kalantar-zadeh and published by Springer Science & Business Media. This book was released on 2007-09-19 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology provides tools for creating functional materials, devices, and systems by controlling materials at the atomic and molecular scales and making use of novel properties and phenomena. Nanotechnology-enabled sensors find applications in several fields such as health and safety, medicine, process control and diagnostics. This book provides the reader with information on how nanotechnology enabled sensors are currently being used and how they will be used in the future in such diverse fields as communications, building and facilities, medicine, safety, and security, including both homeland defense and military operations.

Metal Oxide Nanostructures

Author : Daniela Nunes
Publisher : Elsevier
ISBN 13 : 012811505X
Total Pages : 331 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Metal Oxide Nanostructures by : Daniela Nunes

Download or read book Metal Oxide Nanostructures written by Daniela Nunes and published by Elsevier. This book was released on 2018-11-01 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Oxide Nanostructures: Synthesis, Properties and Applications covers the theoretical and experimental aspects related to design, synthesis, fabrication, processing, structural, morphological, optical and electronic properties on the topic. In addition, it reviews surface functionalization and hybrid materials, focusing on the advantages of these oxide nanostructures. The book concludes with the current and future prospective applications of these materials. Users will find a complete overview of all the important topics related to oxide nanostructures, from the physics of the materials, to its application. - Delves into hybrid structured metal oxides and their promising use in the next generation of electronic devices - Includes fundamental chapters on synthesis design and the properties of metal oxide nanostructures - Provides an in-depth overview of novel applications, including chromogenics, electronics and energy

Optical Biosensors

Author : Frances S. Ligler
Publisher : Elsevier
ISBN 13 : 0080564941
Total Pages : 721 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Optical Biosensors by : Frances S. Ligler

Download or read book Optical Biosensors written by Frances S. Ligler and published by Elsevier. This book was released on 2011-10-13 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Biosensors, Second Edition describes the principles of successful systems, examples of applications, and evaluates the advantages and deficiencies of each. It also addresses future developments on two levels: possible improvements in existing systems and emerging technologies that could provide new capabilities in the future. The book is formatted for ease of use and is therefore suitable for scientists and engineers, students and researcher at all levels in the field. - Comprehensive analysis and review of the underlying principles by optical biosensors - Updates and informs on all the latest developments and hot topic areas - Evaluates current methods showing the advantages and disadvantages of various systems involved

Nanostructured Materials in Electrochemistry

Author : Ali Eftekhari
Publisher : John Wiley & Sons
ISBN 13 : 3527621512
Total Pages : 489 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Nanostructured Materials in Electrochemistry by : Ali Eftekhari

Download or read book Nanostructured Materials in Electrochemistry written by Ali Eftekhari and published by John Wiley & Sons. This book was released on 2008-06-25 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing the unique and vital link between the worlds of electrochemistry and nanomaterials, this reference and handbook covers advances in electrochemistry through the nanoscale control of electrode structures, as well as advances in nanotechnology through electrochemical synthesis strategies. It demonstrates how electrochemical methods are of great scientific and commercial interest due to their low cost and high efficiency, and includes the synthesis of nanowires, nanoparticles, nanoporous and layered nanomaterials of various compositions, as well as their applications -- ranging from superior electrode materials to energy storage, biosensors, and electroanalytical devices.

Nanotechnological Basis for Advanced Sensors

Author : Johann Peter Reithmaier
Publisher : Springer
ISBN 13 : 940070903X
Total Pages : 577 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Nanotechnological Basis for Advanced Sensors by : Johann Peter Reithmaier

Download or read book Nanotechnological Basis for Advanced Sensors written by Johann Peter Reithmaier and published by Springer. This book was released on 2011-04-21 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together experts from 15 countries, this book is based on the lectures and contributions of the NATO Advanced Study Institute on “Nanotechnological Basis for Advanced Sensors” held in Sozopol, Bulgaria, 30 May - 11 June, 2010. It gives a broad overview on this topic, and includes articles on: techniques for preparation and characterization of sensor materials; different types of nanoscaled materials for sensor applications, addressing both their structure (nanoparticles, nanocomposites, nanostructured films, etc.) and chemical nature (carbon-based, oxides, glasses, etc.); and on advanced sensors that exploit nanoscience and nanotechnology. In addition, the volume represents an interdisciplinary approach with authors coming from diverse fields such as physics, chemistry, engineering, materials science and biology. A particular strength of the book is its combination of longer papers, introducing the basic knowledge on a certain topic, and brief contributions highlighting special types of sensors and sensor materials.