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Author :
Publisher : Elsevier
ISBN 13 : 0080862039
Total Pages : 660 pages
Book Rating : 4.0/5 (88 download)
Download or read book Transplantation into the Mammalian CNS written by and published by Elsevier. This book was released on 1988-12-01 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transplantation into the Mammalian CNS
Author : Anders Björklund
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 746 pages
Book Rating : 4.3/5 (91 download)
Download or read book Neural Grafting in the Mammalian CNS written by Anders Björklund and published by Elsevier Publishing Company. This book was released on 1985 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John R. Sladek
Publisher :
ISBN 13 : 9781468446869
Total Pages : 488 pages
Book Rating : 4.4/5 (468 download)
Download or read book Neural Transplants written by John R. Sladek and published by . This book was released on 2014-01-15 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John R. Sladek
Publisher : Springer Science & Business Media
ISBN 13 : 1468446851
Total Pages : 468 pages
Book Rating : 4.4/5 (684 download)
Download or read book Neural Transplants written by John R. Sladek and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of mammalian neural transplantation really begins eighty-one years ago. In Chicago in December of 1903, a 34-year-old physician, Elizabeth Hopkins Dunn, working as a research assistant in neurology, initiated a series of experiments to examine the ability of neonatal rat cerebral tissue to survive transplantation into the brain of matched littermates. Out of 46 attempts, four clearly successful grafts were identified. The publication of Dunn's results in 1917, the first credible report to demonstrate the feasibility of mammalian CNS transplants, generated little interest. In fact, the next significant experiment in this field did not appear until 1930. The field continued to grow slowly and quietly as investigators gradually realized the value of neural trans plantation to study problems of development and plasticity in the mammalian nervous system. With the discovery in 1979 that grafted neurons were capable of appropriate and functional interactions with the host brain, interest in neural transplantation esca lated sharply. The extraordinary opportunities created by using functional neural trans plants in investigating basic issues in neurobiology, as well as the clinical implications, excited both scientists and the public. The popularity of neural transplantation has been growing rapidly in the past five years and shows no signs of abating. The present volume was designed to meet two needs created by the rapid growth of this subdiscipline of neurobiology. The first was to provide a thorough review of the experimental foundations of neural transplantation.
Author : William J. Freed
Publisher : MIT Press
ISBN 13 : 9780262062084
Total Pages : 590 pages
Book Rating : 4.0/5 (62 download)
Download or read book Neural Transplantation written by William J. Freed and published by MIT Press. This book was released on 2000 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: After providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.
Author : Stephen B. Dunnett
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 616 pages
Book Rating : 4.3/5 (91 download)
Download or read book Functional Neural Transplantation written by Stephen B. Dunnett and published by Lippincott Williams & Wilkins. This book was released on 1994 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stephen B. Dunnett
Publisher : Irl Press
ISBN 13 : 9780199632855
Total Pages : 211 pages
Book Rating : 4.6/5 (328 download)
Download or read book Neural Transplantation written by Stephen B. Dunnett and published by Irl Press. This book was released on 1992 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance, and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered. Specialized chapters consider genetic engineering of cells, labelling of grafts, and other aspects of tissue manipulation of PNS and gilal tissues; transplantation in neonatal animals, including primates; handling of human embryonic tissues for transplantation; and immunological considerations. The book will be of interest to neuroscientists studying neural development, anatomical plasticity, functional organization, and recovery in the mammalian CNS, and to neurologists and neurosurgeons interested in developing clinical applications of neural transplantation. It should be stressed that these techniques are experimental and not yet for clinical use.
Author : John Barton Furness
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Enteric Nervous System written by John Barton Furness and published by . This book was released on 1987 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : United States. Congress. Office of Technology Assessment
Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.3/5 (121 download)
Download or read book Neural Grafting written by United States. Congress. Office of Technology Assessment and published by . This book was released on 1990 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Congress of the United States Office of
Publisher : The Minerva Group, Inc.
ISBN 13 : 9780898759075
Total Pages : 208 pages
Book Rating : 4.7/5 (59 download)
Download or read book Neural Grafting written by Congress of the United States Office of and published by The Minerva Group, Inc.. This book was released on 2002-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Santiago Ramón y Cajal
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cajal on the Cerebral Cortex written by Santiago Ramón y Cajal and published by . This book was released on 1988 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first English-language publication of the complete works of the great Spanish neurohistologist, Santiago Ramon y Cajal, on the cerebral cortex. The new translations include all Cajal's very early contributions on the cortex of small mammals, relevant chapters from his definitive textbook, and all his great works on the human cerebral cortex made at the peak of his career. The book also presents Cajal's surveys of cortical structure dating from his later years. It is extensively annotated, and the editors have verified and completed all Cajal's references. Special introductory chapters review the state of knowledge during each period covered, and the work concludes with an extensive essay on modern cortical neurohistology in which the quality and lasting significance of Cajal's contributions are highlighted.
Author : Michael E. Selzer
Publisher : Cambridge University Press
ISBN 13 : 1107011671
Total Pages : 693 pages
Book Rating : 4.1/5 (7 download)
Download or read book Textbook of Neural Repair and Rehabilitation written by Michael E. Selzer and published by Cambridge University Press. This book was released on 2014 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.
Author : Joe Marwah
Publisher : CRC Press
ISBN 13 : 9780849386831
Total Pages : 304 pages
Book Rating : 4.3/5 (868 download)
Download or read book Neural Transplantation, CNS Neuronal Injury, and Regeneration written by Joe Marwah and published by CRC Press. This book was released on 1994-02-23 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique reference presents studies from leading laboratories that are studying the effects of CNS transplants on neuronal plasticity and recovery of function after CNS injury. Topics covered include tropic influences, reinnervation patterns, and prevention of cell death that range from pre-clinical models of Parkinson's disease in primates to studies of restoration of circadian rhythms in rats. Techniques of neurotransplantation are presented, including current limitations and future projections of advancement.
Author : R.B. Wallace
Publisher : Springer Science & Business Media
ISBN 13 : 1461255392
Total Pages : 250 pages
Book Rating : 4.4/5 (612 download)
Download or read book Neural Tissue Transplantation Research written by R.B. Wallace and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decade research on neural transplantation in mammals has grown extensively, and has attracted the attention of many young inquisitive scientists. This growth, as the critics point out, has been somewhat random, and has resulted neither in the formulation of basic concepts nor in any other significant achievement. For instance, they question-how is it possible to jump into functional research with clinical bearing when the basic morphological work has not yet been conducted? The criticism, objectively speaking, is valid and is supported by the fact that every investigator who has stepped into this unex plored field of neurosciences has formulated questions in his own way, has followed his own "model" oftransplantation, and has arrived at his own unique conclusions. The potential danger, as the critics emphasize, in this type of approach lies in that instead of evolving into a scientifically solid and valuable field of research, it may end in a confusing and conflicting mass of questionable claims and subjective opinions. The present situation, very likely, is a reflection of unrestrained enthusiasm and imaginativeness of the investigators, and the demands of the times for the so-called "newsworthy" and "breakthrough" publications. Despite these limitations, two important facts have been estab lished in this field. First, as far as transplantation of neural tissues per se is concerned, what was considered impossible by some critics about 10-12 years ago has been shown to be possible.
Author : Tanja Zigova
Publisher : Springer Science & Business Media
ISBN 13 : 1592592988
Total Pages : 434 pages
Book Rating : 4.5/5 (925 download)
Download or read book Neural Stem Cells for Brain and Spinal Cord Repair written by Tanja Zigova and published by Springer Science & Business Media. This book was released on 2002-11-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.
Author : Horst Przuntek
Publisher : Springer Science & Business Media
ISBN 13 : 3709189942
Total Pages : 356 pages
Book Rating : 4.7/5 (91 download)
Download or read book Early Diagnosis and Preventive Therapy in Parkinson’s Disease written by Horst Przuntek and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the time when "Parkinson's Disease" is diagnosed in a patient, roughly two thirds of dopaminergic neurons of substantia nigra are already degenerated. The onset of the disease must, therefore, be much earlier. This book deals with early diagnosis and early preventive treatment which may sustain the process underlying the disease. By use of psychometric, kinesiologic, physiologic, histologic, biochemical, endocrinologic, pharmacologic and imaging techniques, including positron-emission tomography and brain mapping, specialists tried to focus on new diagnostic criteria. New methods including psychometric evaluation, apparative measurement of movement, analysis of peripheral blood and urinary constituents have supplemented this approach. It has been agreed that early preventive therapy consists of low dosis of L-DOPA plus benserazide, L-deprenyl and dopaminergic agonists.
Author : Abel Lajtha
Publisher : Springer Science & Business Media
ISBN 13 : 0387326707
Total Pages : 332 pages
Book Rating : 4.3/5 (873 download)
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2008-06-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system is highly fragile, especially during aging, illness and trauma. This book addresses a small sampling of major constituents of neural function at the cellular and molecular level that play crucial roles in development and aging.
