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Transcriptional Regulation Of Oxygen Responsive Genes In Saccharomyces Cerevisiae
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Book Synopsis Transcriptional Regulation of Oxygen-responsive Genes in Saccharomyces Cerevisiae by : Johanna Josephina Maria ter Linde
Download or read book Transcriptional Regulation of Oxygen-responsive Genes in Saccharomyces Cerevisiae written by Johanna Josephina Maria ter Linde and published by . This book was released on 2003 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Oxygen Provision on the Physiology of Baker's Yeast Saccharomyces Cerevisiae by : Eija Rintala
Download or read book Effects of Oxygen Provision on the Physiology of Baker's Yeast Saccharomyces Cerevisiae written by Eija Rintala and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The availability of oxygen has a major effect on all organisms. The yeast Saccharomyces cerevisiae is able to adapt its metabolism for growth in different conditions of oxygen provision, and to grow even under complete lack of oxygen. Although the physiology of S. cerevisiae has mainly been studied under fully aerobic and anaerobic conditions, less is known of metabolism under oxygen-limited conditions and of the adaptation to changing conditions of oxygen provision. This study compared the physiology of S. cerevisiae in conditions of five levels of oxygen provision (0, 0.5, 1.0, 2.8 and 20.9% O2 in feed gas) by using measurements on metabolite, transcriptome and proteome levels. On the transcriptional level, the main differences were observed between the three level groups, 0, 0.5-2.8 and 20.9% O2 which led to fully fermentative, respirofermentative and fully respiratory modes of metabolism, respectively. However, proteome analysis suggested post-transcriptional regulation at the level of 0.5 O2. The analysis of metabolite and transcript levels of central carbon metabolism also suggested post-transcriptional regulation especially in glycolysis. Further, a global upregulation of genes related to respiratory pathways was observed in the oxygen-limited conditions and the same trend was seen in the proteome analysis and in the activities of enzymes of the TCA cycle. The responses of intracellular metabolites related to central carbon metabolism and transcriptional responses to change in oxygen availability were studied. As a response to sudden oxygen depletion, concentrations of the metabolites of central carbon metabolism responded faster than the corresponding levels of gene expression. In general, the genome-wide transcriptional responses to oxygen depletion were highly similar when two different initial conditions of oxygen provision (20.9 and 1.0% O2) were compared. The genes related to growth and cell proliferation were transiently downregulated whereas the genes related to protein degradation and phosphate uptake were transiently upregulated. In the cultures initially receiving 1.0% O2, a transient upregulation of genes related to fatty acid oxidation, peroxisomal biogenesis, response to oxidative stress and pentose phosphate pathway was observed. Additionally, this work analysed the effect of oxygen on transcription of genes belonging to the hexose transporter gene family. Although the specific glucose uptake rate was highest in fully anaerobic conditions, none of the hxt genes showed highest expression in anaerobic conditions. However, the expression of genes encoding the moderately low affinity transporters decreased with the decreasing oxygen level. Thus it was concluded that there is a relative increase in high affinity transport in anaerobic conditions supporting the high uptake rate.
Book Synopsis Oxygen-responsive Gene Network Analyses in Saccharomyces Cerevisiae by : Liang-Chuan Lai
Download or read book Oxygen-responsive Gene Network Analyses in Saccharomyces Cerevisiae written by Liang-Chuan Lai and published by . This book was released on 2005 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transcriptional Regulation of a Stress Inducible Gene of Saccharomyces Cerevisiae by : Naoko Kobayashi
Download or read book Transcriptional Regulation of a Stress Inducible Gene of Saccharomyces Cerevisiae written by Naoko Kobayashi and published by . This book was released on 1990 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mechanisms of Transcriptional Control in Phosphate-responsive Signaling Pathway of Saccharomyces Cerevisiae by : Xu Zhou
Download or read book Mechanisms of Transcriptional Control in Phosphate-responsive Signaling Pathway of Saccharomyces Cerevisiae written by Xu Zhou and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulation of gene expression is essential for many biological processes. Binding of transcription factors to DNA is a key regulatory step in the control of gene expression. It is commonly observed that DNA sequences with high affinity for transcription factors occur more frequently in the genome than the instances of genes bound or regulated by these factors. However, the mechanism by which transcription factors selectively identify and regulate these genes was unclear. I utilized the transcriptional control of the phosphate-responsive signaling pathway (PHO) in Saccharomyces cerevisiae as a model system to address this problem.
Book Synopsis Transcriptional Regulation in Response to Environmental Signals in the Yeast Saccharomyces Cerevisiae by : Mary Emily Gray
Download or read book Transcriptional Regulation in Response to Environmental Signals in the Yeast Saccharomyces Cerevisiae written by Mary Emily Gray and published by . This book was released on 2001 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Handbook of Statistical Analyses using R, Third Edition by : Torsten Hothorn
Download or read book A Handbook of Statistical Analyses using R, Third Edition written by Torsten Hothorn and published by CRC Press. This book was released on 2014-06-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like the best-selling first two editions, A Handbook of Statistical Analyses using R, Third Edition provides an up-to-date guide to data analysis using the R system for statistical computing. The book explains how to conduct a range of statistical analyses, from simple inference to recursive partitioning to cluster analysis. New to the Third Edition Three new chapters on quantile regression, missing values, and Bayesian inference Extra material in the logistic regression chapter that describes a regression model for ordered categorical response variables Additional exercises More detailed explanations of R code New section in each chapter summarizing the results of the analyses Updated version of the HSAUR package (HSAUR3), which includes some slides that can be used in introductory statistics courses Whether you’re a data analyst, scientist, or student, this handbook shows you how to easily use R to effectively evaluate your data. With numerous real-world examples, it emphasizes the practical application and interpretation of results.
Book Synopsis Transcriptional Regulation at the G2/M Transition in the Budding Yeast, Saccharomyces Cerevisiae by : David Matthew Reynolds
Download or read book Transcriptional Regulation at the G2/M Transition in the Budding Yeast, Saccharomyces Cerevisiae written by David Matthew Reynolds and published by . This book was released on 2002 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis the biochemical and genetic characterization of Fkh2p identifies it as a major component of SFF. It has been shown to bind DNA in an Mcm1p dependent manner and the Fkh2p DNA binding domain is essential for this interaction. The protein interaction domain of Mcm1p has been demonstrated to be essential for ternary complex formation. Fkh2p, along with a functionally redundant protein Fkh1p, has been show to control the periodic expression of the CLB2 cluster genes. The functional characterisation of the Fkh2p domains reveals an important role for both the Forkhead associated domain and the C-terminus. Ndd1p. another protein important for mitotic progression, is shown to be important for CLB2 cluster regulation by de-repressing Fkh2p and activating gene expression. The role of cdk activity is shown to act through the CLB2 cluster upstream activating sequences, possibly through Ndd1p.
Book Synopsis Transcriptional Regulation of Ribosomal Protein Genes in Saccharomyces Cerevisiae by : Romeo Franciscus Lascaris
Download or read book Transcriptional Regulation of Ribosomal Protein Genes in Saccharomyces Cerevisiae written by Romeo Franciscus Lascaris and published by . This book was released on 2001 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Yeast Stress Responses by : Stefan Hohmann
Download or read book Yeast Stress Responses written by Stefan Hohmann and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every cell has developed mechanisms to respond to changes in its environment and to adapt its growth and metabolism to unfavorable conditions. The unicellular eukaryote yeast has long proven as a particularly useful model system for the analysis of cellular stress responses, and the completion of the yeast genome sequence has only added to its power This volume comprehensively reviews both the basic features of the yeast genral stress response and the specific adapations to different stress types (nutrient depletion, osmotic and heat shock as well as salt and oxidative stress). It includes the latest findings in the field and discusses the implications for the analysis of stress response mechanisms in higher eukaryotes as well.
Book Synopsis Coordinate Regulation of Glycolytic Gene Expression in Saccharomyces Cerevisiae by : Chang Seo Park
Download or read book Coordinate Regulation of Glycolytic Gene Expression in Saccharomyces Cerevisiae written by Chang Seo Park and published by . This book was released on 1994 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transcriptional Regulation of the Sterol Biosynthetic Pathway in Saccharomyces Cerevisiae by : Ashild Vik
Download or read book Transcriptional Regulation of the Sterol Biosynthetic Pathway in Saccharomyces Cerevisiae written by Ashild Vik and published by . This book was released on 2001 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genome-wide Analysis of Transcriptional Expression Programs, Regulatory Networks and Cis-regulatory Sequences in Saccharomyces Cerevisiae by : Christopher T. Harbison
Download or read book Genome-wide Analysis of Transcriptional Expression Programs, Regulatory Networks and Cis-regulatory Sequences in Saccharomyces Cerevisiae written by Christopher T. Harbison and published by . This book was released on 2005 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, knowledge of gene-specific transcription has been accumulated by the study of the individual genetic and physical interactions between transcriptional regulators and the genes they regulate, often requiring considerable time and effort. Microarray technology now enables investigation of gene expression at the level of the entire genome, allowing researchers access to rich datasets and promising new levels of depth in the understanding of transcriptional regulation. Our lab has made use of these technologies both to measure the levels of all mRNA transcripts within a population of cells, as well as to locate the regions within the genome that are bound by transcriptional regulators. Such studies not only allow for the functional annotation of both genes and regulators, but can also provide clues about the identity of the regulatory regions within DNA, the structure of global regulatory networks and the regulation of DNA-binding proteins. These and other insights are presented here based on our genome-wide studies of transcriptional regulation in the yeast Saccharomyces cerevisiae.
Book Synopsis Saccharomyces Cerevisiae as a Model for Tumor Metabolism by : Wei Gao
Download or read book Saccharomyces Cerevisiae as a Model for Tumor Metabolism written by Wei Gao and published by . This book was released on 1996 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Connections Between Growth and Division by : Laura Lynn Newcomb
Download or read book Connections Between Growth and Division written by Laura Lynn Newcomb and published by . This book was released on 2001 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transcriptional Regulation of the TRP4 and ADE4 Genes in the Yeast “Saccharomyces Cerevisiae” by : Hans-Ulrich Mösch
Download or read book Transcriptional Regulation of the TRP4 and ADE4 Genes in the Yeast “Saccharomyces Cerevisiae” written by Hans-Ulrich Mösch and published by . This book was released on 1991 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transcriptional Regulation of One-carbon Metabolism Genes of Saccharomyces Cerevisiae by : Seung-Pyo Hong
Download or read book Transcriptional Regulation of One-carbon Metabolism Genes of Saccharomyces Cerevisiae written by Seung-Pyo Hong and published by . This book was released on 1999 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
