Trace Amines

Download Trace Amines full books in PDF, epub, and Kindle. Read online Trace Amines ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Trace Amines and Neurological Disorders

Author : Tahira Farooqui
Publisher : Academic Press
ISBN 13 : 0128036168
Total Pages : 432 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Trace Amines and Neurological Disorders by : Tahira Farooqui

Download or read book Trace Amines and Neurological Disorders written by Tahira Farooqui and published by Academic Press. This book was released on 2016-07-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders. Focuses on recent findings on trace amines, providing insights into the functional significance, molecular mechanisms, and biological relevance of TAARS in neurological disorders Edited work with chapters authored by leaders in the field from around the globe, the broadest, most expert coverage available Provides cutting-edge research on trace amines-mediated signaling in vertebrate model systems

Trace Amines

Author : Alan A. Boulton
Publisher : Springer Science & Business Media
ISBN 13 : 1461246024
Total Pages : 473 pages
Book Rating : 4.4/5 (612 download)

DOWNLOAD NOW!

Book Synopsis Trace Amines by : Alan A. Boulton

Download or read book Trace Amines written by Alan A. Boulton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third Proceedings book to arise from biennial conferen ces on the Trace Amines. Since our first meeting in 1983 in Edmonton, Canada, progress has been brisk and, as will be seen from the ensuing pages, it is now possible to include major contributions from inverte brate neurobiologists as well as receptorologists. In the opening ses sion we heard about the distribution of the trace amines-now clear ly a misnomer-in insects and the pharmacological, receptor, and syn aptic characteristics of octopamine and tryptamine as well as the pos sibility of monoamines in general being targets for insecticide discov ery. In mammalian brain the distribution and characterization of the tryptamine receptor has proceeded to the point where two types have been described as well as novel agonists and antagonists, and, for the first time, a binding site for p-tyramine has been described. The com bination of lesions and pharmacological and metabolic manipulations now permits the mapping of trace aminergic pathways, and the rap idly accumulating evidence from releasing drugs, in situ microdialy sis, iontophoresis, and second messenger systems lends credence to the claim that the trace amines possess neuromodulatory functions.

Neurobiology of the Trace Amines

Author : Alan A. Boulton
Publisher : Springer Science & Business Media
ISBN 13 : 1461253128
Total Pages : 584 pages
Book Rating : 4.4/5 (612 download)

DOWNLOAD NOW!

Book Synopsis Neurobiology of the Trace Amines by : Alan A. Boulton

Download or read book Neurobiology of the Trace Amines written by Alan A. Boulton and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the trace amines-more correctly called biogenic amines have been known for decades, but because of their tiny concentra tions (0. 01-100 ng/g) in brain, it was only after the development of sophisticated analytical techniques (such as mass spectrometry) that they could be identified and quantitated in nervous tissue. There are now more than 20 of them and most are related to the catecholamines and 5-hydroxytryptamine both structurally and metabolically. Their pharmacological and physiological properties make them prime candidates for a transmitter or neuromodulator role and many of them elicit profound behavioral syndromes after injection--one of them, phenylethylamine, has even been referred to as nature's amphetamine. In the clinical sphere several have been shown to be involved in: Parkinsonism, schizophrenia, depression, agoraphobia, aggression, hyperkinesis, migraine, hypertensive crises, hypertyrosinemia, he patic encephalopathy, epilepsy, and cystic fibrosis. Thus the research reported here on these intriguing "new" substances will be of great interest to psychiatrists, neurologists, biochemists, pharmacologists, physiologists, psychologists, behaviorists and indeed to all those working in the neurosciences and related fields today. ACKNOWLEDGMENTS This book is based on the proceedings of Trace Amines and the Neurosciences, a meeting held at the University of Alberta, Edmonton, July 19-21, 1983. This meeting was organized as a Satellite Meeting of the Ninth Meeting of the International Society for Neurochemistry, held in Vancouver, July 10-15, 1983. International organizers of the satellite meeting were Drs. A.A. Boulton (Saskatoon), W.G. Dewhurst (Edmonton), G.B. Baker (Edmonton), and M. Sandler (London)

Neuropsychopharmacology of the Trace Amines

Author : Alan A. Boulton
Publisher : Springer Science & Business Media
ISBN 13 : 1461250102
Total Pages : 508 pages
Book Rating : 4.4/5 (612 download)

DOWNLOAD NOW!

Book Synopsis Neuropsychopharmacology of the Trace Amines by : Alan A. Boulton

Download or read book Neuropsychopharmacology of the Trace Amines written by Alan A. Boulton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: A probable neurobiological role for the trace amines began to emerge as soon as techniques sufficiently sophisticated to detect them were developed. Techniques for quantitative analyses included radioenzymatic procedures and, more recently, HPlC-EC and auto mated GC-MS. The methods are applied after separation of the sub stances to be analyzed and after their purification by physicochemical procedures that are becoming more and more efficient. The identification and quantitative analysis of minute amounts of trace amines in biological fluids or tissues is in itself a remarkable technological achievement. The enormous task that several teams of research workers have set themselves is to investigate the origin of the trace amines, to understand their metabolism, and to discover whether or not they possess an important biological role. The 2nd Trace Amines Symposium at Weitenburg Castle near Tubingen from the 15th to the 19th May 1985 was held to gain a somewhat clearer insight into the present state of knowledge. Since the first meeting in 1983 our knowledge has increased and interest is deepening. Hence the idea proposed at that first meeting, of organizing similar gather ings at regular intervals, has come to fruition. Covered in the Neuropsychopharmacology section of this book are studiesof the effects of certain trace amines on different forms of be havior, on neurotransmission mediated by . the classical neuro transmitters, on their biosynthesis or on catabolism, on their possible occurrence as a result of alternative metabolic pathways for the amino acids, and in some instances their neuroanatomical distributions.

Diet and Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Diet and Health by : National Research Council

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

How Tobacco Smoke Causes Disease

Author :
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!

Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Molecular Basis of Odor

Author : John E. Amoore
Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Molecular Basis of Odor by : John E. Amoore

Download or read book Molecular Basis of Odor written by John E. Amoore and published by . This book was released on 1970 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Trace Amines and the Brain

Author : Earl Usdin
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (45 download)

DOWNLOAD NOW!

Book Synopsis Trace Amines and the Brain by : Earl Usdin

Download or read book Trace Amines and the Brain written by Earl Usdin and published by Marcel Dekker. This book was released on 1976 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroanatomical Tract-Tracing

Author : Laszlo Zaborszky
Publisher : Springer Science & Business Media
ISBN 13 : 0387289429
Total Pages : 703 pages
Book Rating : 4.3/5 (872 download)

DOWNLOAD NOW!

Book Synopsis Neuroanatomical Tract-Tracing by : Laszlo Zaborszky

Download or read book Neuroanatomical Tract-Tracing written by Laszlo Zaborszky and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI techniques.

Impact of Processing on Food Safety

Author : Lauren S. Jackson
Publisher : Springer Science & Business Media
ISBN 13 : 1461548535
Total Pages : 265 pages
Book Rating : 4.4/5 (615 download)

DOWNLOAD NOW!

Book Synopsis Impact of Processing on Food Safety by : Lauren S. Jackson

Download or read book Impact of Processing on Food Safety written by Lauren S. Jackson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this book are the proceedings of the ACS symposium, "Impact of Processing on Food Safety," which was held April 16-17, 1997, at the American Chemical Society National Meeting in San Francisco, CA. This symposium brought together re searchers from diverse backgrounds in academia, government, and industry. Twenty speakers discussed topics ranging from the regulatory aspects of food processing to the microbiological and chemical changes in food during processing. The main goal of food processing is to improve the microbial safety of food by de stroying pathogenic and spoilage organisms. Food processing can also improve food safety by destroying or eliminating naturally occurring toxins, chemical contaminants, and antinutritive factors. Unfortunately, processing can also cause chemical changes that result in the formation of toxic or antinutritive factors. The purpose of this book is to summarize our knowledge of both the beneficial and deleterious effects of processing. Chapter I con siders the consumer's perceptions about food contaminants and food processing. Chapter 2 summarizes the effects of traditional and nontraditional processing methods on microor ganisms in food. Chapters 3-6 review the effects of processing on lipids (fatty acids and cholesterol) in food. Changes in the nutritive value of vitamins and minerals as a result of processing are discussed in chapter 7. Chapter 8 concentrates on how processing reduces the allergenicity of some foods.

Trace Amines and the Brain

Author : Earl Usdin
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Trace Amines and the Brain by : Earl Usdin

Chemosensory Transduction

Author : Frank Zufall
Publisher : Academic Press
ISBN 13 : 0128017864
Total Pages : 430 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Chemosensory Transduction by : Frank Zufall

Download or read book Chemosensory Transduction written by Frank Zufall and published by Academic Press. This book was released on 2016-02-18 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University’s Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals. Provides a comprehensive overview for all chemosensory transduction mechanisms Valuable for academics focused on sensory biology, neurobiology, and chemosensory transduction, as well as industry researchers in new flavor, fragrance, and food testing Edited by leading experts in the field of olfactory transduction Focuses on mammals, but lower vertebrates and invertebrate model systems are also included

Drug Addiction

Author : Rao S. Rapaka
Publisher : Springer Science & Business Media
ISBN 13 : 0387766782
Total Pages : 791 pages
Book Rating : 4.3/5 (877 download)

DOWNLOAD NOW!

Book Synopsis Drug Addiction by : Rao S. Rapaka

Download or read book Drug Addiction written by Rao S. Rapaka and published by Springer Science & Business Media. This book was released on 2008-06-19 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of physiological, biochemical, and genetic pathways underlying drug addiction, and resultant efforts to develop novel treatment strategies dealing with drug addiction and other CNS disorders where the neurophysiological processes overlap, such as treatment of pain. The volume focuses on the translation of fundamental addiction research to a variety of treatments and brings together scientists with wide ranging expertise.

Nutrient Metabolism

Author : Martin Kohlmeier
Publisher : Academic Press
ISBN 13 : 0123877881
Total Pages : 899 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Nutrient Metabolism by : Martin Kohlmeier

Download or read book Nutrient Metabolism written by Martin Kohlmeier and published by Academic Press. This book was released on 2015-05-12 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrient Metabolism, Second Edition, provides a comprehensive overview of the supply and use of nutrients in the human body and how the body regulates intake. Chapters detail the principles determining digestion and absorption of food ingredients and how these compounds and their metabolites get into the brain, cross the placenta and pass through the kidneys. Each nutrient’s coverage contains a nutritional summary that describes its function, its food sources, dietary requirements, potential health risks if deficient, and impact of excessive intake. This handbook contains the latest information on the scope of structures, processes, genes and cofactors involved in maintaining a healthy balance of nutrient supplies. Of interest to a wide range of professionals because nutrient issues connect to so many audiences, the book contains a useful link to dietary supplements. Latest research findings on health and clinical effects of nutrients and of interventions affecting nutrient supply or metabolism Each nutrient covered contains a nutritional summary describing its function, food sources, dietary requirements, potential health risks if deficient, and impact of excessive intake. Nutrient information immediately accessible--from source to effect--in one volume

Neuromorphic Olfaction

Author : Krishna C. Persaud
Publisher : CRC Press
ISBN 13 : 1439871728
Total Pages : 237 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Neuromorphic Olfaction by : Krishna C. Persaud

Download or read book Neuromorphic Olfaction written by Krishna C. Persaud and published by CRC Press. This book was released on 2016-04-19 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Magnesium in the Central Nervous System

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

DOWNLOAD NOW!

Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Olfactory Receptors

Author : Fabio Marques Simoes de Souza
Publisher : Humana Press
ISBN 13 : 9781493986088
Total Pages : 390 pages
Book Rating : 4.9/5 (86 download)

DOWNLOAD NOW!

Book Synopsis Olfactory Receptors by : Fabio Marques Simoes de Souza

Download or read book Olfactory Receptors written by Fabio Marques Simoes de Souza and published by Humana Press. This book was released on 2018-06-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores olfactory receptors, a topic that goes beyond classical biochemical essays and involves methods to investigate the brain areas associated with the perception of odorants. Gathering the strands of many advanced techniques, the book organizes these key methods in order to achieve a unifying comprehension of the olfactory system. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and multidisciplinary, Olfactory Receptors: Methods and Protocols serves to benefit not only those who are beginning in the field of olfactory receptors, but also those who are already working in the field and that want to learn another advanced techniques.