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Toxins And Targets
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Book Synopsis Toxins and Targets by : Dianne Watters
Download or read book Toxins and Targets written by Dianne Watters and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment. In order to control competitors for human food sources, an armament of pesticides has been assembled and their widespread and largely uncontrolled application has been permitted. It is only when the health of the population begins to suffer from the effects of these chemicals that the efficacy of their use is questioned. Decision-makers whose roles involve the promotion and control of the environment must look to lessons that can be learnt from biosystems that include animals other than man. Toxins and Targets details the way in which organisms from diverse habitats in the plant and animal kingdoms have adapted to handle toxins safely. Part I, on the aquatic environment, highlights the means by which marine organisms have adapted their toxins to be effective in a world of high aqueous solubility and infinite dilution. Part II deals with venomous terrestrial organisms and the mechanisms by which they damage animal cells, and Part III considers the way in which human society attempts to investigate toxicity and to control both synthetic and naturally occurring poisons. The development of a safe environment depends on increased knowledge and novel approaches to solving escalating problems. This book is a step towards this end.
Book Synopsis Toxins and Targets by : Dianne Watters
Download or read book Toxins and Targets written by Dianne Watters and published by Taylor & Francis. This book was released on 2022-11-12 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment. In order to control competitors for human food sources, an armament of pesticides has been assembled and their widespread and largely uncontrolled application has been permitted. It is only when the health of the population begins to suffer from the effects of these chemicals that the efficacy of their use is questioned. Decision-makers whose roles involve the promotion and control of the environment must look to lessons that can be learnt from biosystems that include animals other than man. Toxins and Targets details the way in which organisms from diverse habitats in the plant and animal kingdoms have adapted to handle toxins safely. Part I, on the aquatic environment, highlights the means by which marine organisms have adapted their toxins to be effective in a world of high aqueous solubility and infinite dilution. Part II deals with venomous terrestrial organisms and the mechanisms by which they damage animal cells, and Part III considers the way in which human society attempts to investigate toxicity and to control both synthetic and naturally occurring poisons. The development of a safe environment depends on increased knowledge and novel approaches to solving escalating problems. This book is a step towards this end.
Book Synopsis Monitoring Human Tissues for Toxic Substances by : National Research Council
Download or read book Monitoring Human Tissues for Toxic Substances written by National Research Council and published by National Academies Press. This book was released on 1991-02-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.
Download or read book Toxins and Targets written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pesticide Toxicity to Non-target Organisms by : Johnson Stanley
Download or read book Pesticide Toxicity to Non-target Organisms written by Johnson Stanley and published by Springer. This book was released on 2016-08-12 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pesticide should cause effect on the target pests and be selective enough to spare the non-target beneficial. The book deals with the pesticide toxicity to predators, parasitoids and microbes which are used for pest management in the agroecosystem. The other beneficials exposed to pesticides are pollinators, earthworms, silkworm and fishes. The book contains information on the modes of pesticide exposure and toxicity to the organisms, sub-lethal effects of insecticides and method of toxicity assessment, risk assessment of pesticidal application in the field. The purpose of the work is to compile and present the different procedures to assess pesticide poising in organisms related to the agroecosystem along with discussions on risk assessment procedures with clear comparison of toxicity of pesticides to target pests and non target beneficial organisms.
Book Synopsis Elucidating the in Vivo Targets of Bacterial Toxins by : Elaine Elizabeth Hamm
Download or read book Elucidating the in Vivo Targets of Bacterial Toxins written by Elaine Elizabeth Hamm and published by . This book was released on 2007 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract not available.
Book Synopsis Bacterial Protein Toxins by : K. Aktories
Download or read book Bacterial Protein Toxins written by K. Aktories and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
Book Synopsis Mechanistic Toxicology by : Urs A. Boelsterli
Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Book Synopsis Endogenous Toxins by : Peter J. O'Brien
Download or read book Endogenous Toxins written by Peter J. O'Brien and published by . This book was released on 2009 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bacterial Persistence by : Jan Michiels
Download or read book Bacterial Persistence written by Jan Michiels and published by Humana. This book was released on 2015-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a comprehensive collection of methods that have been instrumental to the current understanding of bacterial persisters. Chapters in the book cover topics ranging from general methods for measuring persister levels in Escherichia coli cultures, protocols for the determination of the persister subpopulation in Candida albicans, quantitative measurements of Type I and Type II persisters using ScanLag, to in vitro and in vivo models for the study of the intracellular activity of antibiotics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Persistence: Methods and Protocols brings together the most respected researchers in bacterial persistence whose studies will remain vital to understanding this field for many years to come.
Book Synopsis Toxins: New Targets and New Functions by : Jordi Molgó
Download or read book Toxins: New Targets and New Functions written by Jordi Molgó and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biological Toxins and Bioterrorism by : P. Gopalakrishnakone
Download or read book Biological Toxins and Bioterrorism written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Book Synopsis Snake Venoms by : P. Gopalakrishnakone
Download or read book Snake Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2017-02-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Book Synopsis The Comprehensive Sourcebook of Bacterial Protein Toxins by : Joseph E. Alouf
Download or read book The Comprehensive Sourcebook of Bacterial Protein Toxins written by Joseph E. Alouf and published by Elsevier. This book was released on 2005-12-20 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology Includes the major toxins of both basic and clinical interest are described in depth Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology Evolutionary and functional aspects of bacterial toxins evaluated and summarized Toxin applications in cell biology presented Therapy (cancer therapy, dystonias) discussed Vaccines (native and genetically engineered vaccines) featured Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.
Book Synopsis Target Organ Toxicity in Marine and Freshwater Teleosts by : Daniel Schlenk
Download or read book Target Organ Toxicity in Marine and Freshwater Teleosts written by Daniel Schlenk and published by CRC Press. This book was released on 2003-09-02 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing the numerous gaps in current information, Target Organ Toxicology in Marine and Freshwater Teleosts is an essential resource for researchers and professionals in aquatic toxicology and environmental risk assessment. All the chapters are written by researchers who are internationally recognised for their work in mechanistic aspects of aquatic toxicology. Each chapter focuses on a specific target organ or physiological system and describes how various agents disrupt the normal physiological system and processes. This volume is devoted to specific organs with coverage of the gill, kidney, skin, liver and gut. The companion volume, Systems, provides coverage of toxic effects in the central nervous, immune, neurobehavioural and reproductive systems as well as describing general mechanisms of toxicity.
Book Synopsis Toxic Communities by : Dorceta E. Taylor
Download or read book Toxic Communities written by Dorceta E. Taylor and published by NYU Press. This book was released on 2014 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: From St. Louis to New Orleans, from Baltimore to Oklahoma City, there are poor and minority neighborhoods so beset by pollution that just living in them can be hazardous to your health. Due to entrenched segregation, zoning ordinances that privilege wealthier communities, or because businesses have found the OCypaths of least resistance, OCO there are many hazardous waste and toxic facilities in these communities, leading residents to experience health and wellness problems on top of the race and class discrimination most already experience. Taking stock of the recent environmental justice scholarship, a Toxic Communities aexamines the connections among residential segregation, zoning, and exposure to environmental hazards. Renowned environmental sociologist Dorceta Taylor focuses on the locations of hazardous facilities in low-income and minority communities and shows how they have been dumped on, contaminated and exposed. Drawing on an array of historical and contemporary case studies from across the country, Taylor explores controversies over racially-motivated decisions in zoning laws, eminent domain, government regulation (or lack thereof), and urban renewal. She provides a comprehensive overview of the debate over whether or not there is a link between environmental transgressions and discrimination, drawing a clear picture of the state of the environmental justice field today and where it is going. In doing so, she introduces new concepts and theories for understanding environmental racism that will be essential for environmental justice scholars. A fascinating landmark study, a Toxic Communities agreatly contributes to the study of race, the environment, and space in the contemporary United States."
Book Synopsis Biologic Markers in Urinary Toxicology by : National Research Council
Download or read book Biologic Markers in Urinary Toxicology written by National Research Council and published by National Academies Press. This book was released on 1995-08-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the kidney, bladder, and prostate exact an enormous human and economic toll on the population of the United States. This book examines prevention of these diseases through the development of reliable markers of susceptibility, exposure, and effect and the promise that new technologies in molecular biology and sophisticated understanding of metabolic pathways, along with classical approaches to the study of nephrotoxicants and carcinogens, can be developed and prevention of the diseases achieved. The specific recommendations included in this book complement those made in the previous three volumes on biomarkers, Biologic Markers in Reproductive Toxicology (1989), Biologic Markers in Pulmonary Toxicology (1989), and Biologic Markers in Immunotoxicology (1991).
