Toxicology of Organophosphate Poisoning

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Author :
Publisher : Springer Nature
ISBN 13 : 3030791289
Total Pages : 112 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Toxicology of Organophosphate Poisoning by : Anuj Ranjan

Download or read book Toxicology of Organophosphate Poisoning written by Anuj Ranjan and published by Springer Nature. This book was released on 2021-10-11 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the consequences of high agricultural pesticide use over the last few decades in the form of organophosphate poisoning. The authors provide a background overview of organophosphate compounds, their environmental toxicity, non-target exposures and cases of human poisoning. The authors also compile and analyze data from the last two decades to demonstrate the toxicological aspects of organophosphates, and how they can pose a threat to human health. Readers will learn about the clinical manifestation of organophosphate exposure in humans, as well as the enzymatic pathways and mechanisms by which organophosphates are processed in the body and cause harm. The book concludes by providing techniques, practices and recommendations for how to manage organophosphate exposure and poisoning. It will be useful for clinicians and public health professionals, scientists, medical practitioners, researchers and environmental toxicologists.

Toxicology of Organophosphate and Carbamate Compounds

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Publisher : Academic Press
ISBN 13 : 0080543103
Total Pages : 781 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Toxicology of Organophosphate and Carbamate Compounds by : Ramesh C Gupta

Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans

Basic and Clinical Toxicology of Organophosphorus Compounds

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1447156250
Total Pages : 264 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Basic and Clinical Toxicology of Organophosphorus Compounds by : Mahdi Balali-Mood

Download or read book Basic and Clinical Toxicology of Organophosphorus Compounds written by Mahdi Balali-Mood and published by Springer Science & Business Media. This book was released on 2013-12-19 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the chemistry of Organophosphorus compounds (OPs), their mechanism of toxicity and the history of OPs from their initial discovery to the development of new compounds such as Novichoks. It details the harmful effects to human health both as a result of acute and chronic OP exposure and the necessary clinical management of affected patients to reduce their toxic side effects. The book also explains the detrimental effect that OPs have had on the environment and the efforts being made to prevent this in the future. Finally, the book looks at the incidents where OPs have been used as chemical warfare agents. Basic and Clinical Toxicology of Organophosphorus Compounds aims to act as a comprehensive guide to all aspects of OPs and is a key resource for clinical toxicologists and related health professionals involved in the prevention, diagnosis and clinical management of OP patients, toxicologists and other scientists involved in research on OPs including regulatory issues and postgraduate students in Toxicology and related fields.

Clinical and Experimental Toxicology of Organophosphates and Carbamates

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Author :
Publisher : Elsevier
ISBN 13 : 1483193659
Total Pages : 662 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Clinical and Experimental Toxicology of Organophosphates and Carbamates by : Bryan Ballantyne

Download or read book Clinical and Experimental Toxicology of Organophosphates and Carbamates written by Bryan Ballantyne and published by Elsevier. This book was released on 2017-01-31 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular events in delayed neuropathy. Other parts deal with the cardiac effects of anticholinesterase agents and the ecotoxicological consequences of interactions between avian esterases and organophosphorus compounds. These topics are followed by discussions on the analysis of the cutaneous and respiratory tract absorption of anticholinesterases and the use of organophosphorus compounds as chemical warfare agents. The final parts are devoted to the toxicity of anticholinesterases to aquatic organisms. The book can provide useful information to toxicologists, doctors, students, and researchers.

Organophosphates And Health

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Author :
Publisher : World Scientific
ISBN 13 : 1783261439
Total Pages : 511 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Organophosphates And Health by : Stanley Feldman

Download or read book Organophosphates And Health written by Stanley Feldman and published by World Scientific. This book was released on 2001-07-24 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few chemical compounds created by man have caused greater controversy than organophosphates. Conceived as insecticides, they have also been developed to become the most feared of chemical weapons. The control of vectors of diseases from which millions die or are disabled is heavily dependent on organophosphates, as are efforts to maintain food production in the face of uncontrolled population growth, diminishing arable land and the possibility of global warming. As the toxicity of organophosphates is non-specific, it has caused ill health and death in man, and has contributed to adverse ecological effects.This book, written by recognised experts, studies and presents information in a manner that basic scientists, medical personnel, environmentalists, agriculturists and those in public health and occupational medicine will find essential when considering the use of organophosphates in their disciplines. The text primarily covers health aspects, with discussions on related social, economic, environmental and agricultural issues that concern all inhabitants of the global village.

MANAGEMENT OF ORGANOPHOSPHORUS PESTICIDE POISONING: COMMON QUESTIONS AND ANSWERS

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Author :
Publisher : Notion Press
ISBN 13 : 1638735980
Total Pages : 208 pages
Book Rating : 4.6/5 (387 download)

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Book Synopsis MANAGEMENT OF ORGANOPHOSPHORUS PESTICIDE POISONING: COMMON QUESTIONS AND ANSWERS by : Kirti S Pawar

Download or read book MANAGEMENT OF ORGANOPHOSPHORUS PESTICIDE POISONING: COMMON QUESTIONS AND ANSWERS written by Kirti S Pawar and published by Notion Press. This book was released on 2021-09-17 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although managing mild organophosphorus poisoning could be quite simple, management of moderate to severe organophosphorus poisoning requires skill and extensive knowledge of this emergency. This book is a comprehensive guide to manage organophosphorus poisoning cases, covering everything from the identification of poison to the treatment. We have endeavored to cover every aspect of diagnosis and treatment, including common names of organophosphorus, carbamates, pyrethroids, and organo-chloro poisons, the types of presentation in organophosphorus poisoning, interpretation of cholinesterase level reports, prevention of intermediate syndrome/reintubation, decisions regarding doses of atropine and pralidoxime (2PAM) and other treatment options in organophosphorus poisoning, how to overcome difficulties in weaning from ventilator, delayed complications and their prevention, differences in treatment of organophosphorus poisoning and carbamates/ pyrethroids/organo-chloro poisons and many more frequently asked questions. This book provides detailed evidence-based answers to 64 questions related to organophosphorus poisoning and would prove invaluable to medical students for conceptual understanding of this topic and to clinicians for the effective management of patients with organophosphorus poisoning.

Recognition and Management of Pesticide Poisonings (5th Ed. )

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Author :
Publisher : DIANE Publishing
ISBN 13 : 1437914527
Total Pages : 238 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Recognition and Management of Pesticide Poisonings (5th Ed. ) by : J. Routt Reigart

Download or read book Recognition and Management of Pesticide Poisonings (5th Ed. ) written by J. Routt Reigart and published by DIANE Publishing. This book was released on 2009-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

Organophosphates Chemistry, Fate, and Effects

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Publisher : Elsevier
ISBN 13 : 0080917267
Total Pages : 462 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Organophosphates Chemistry, Fate, and Effects by : Janice E. Chambers

Download or read book Organophosphates Chemistry, Fate, and Effects written by Janice E. Chambers and published by Elsevier. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo

Environmental Medicine

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Publisher : National Academies Press
ISBN 13 : 0309568722
Total Pages : 988 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Environmental Medicine by : Committee on Curriculum Development in Environmental Medicine

Download or read book Environmental Medicine written by Committee on Curriculum Development in Environmental Medicine and published by National Academies Press. This book was released on 1995-05-12 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.

New Frontiers in Environmental Toxicology

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Publisher : Springer Nature
ISBN 13 : 3030721736
Total Pages : 142 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis New Frontiers in Environmental Toxicology by : Tanu Jindal

Download or read book New Frontiers in Environmental Toxicology written by Tanu Jindal and published by Springer Nature. This book was released on 2021-09-21 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides up-to-date information on toxic pollutants in the environment and their harmful effects on human health and nature. The book covers many important aspects of environmental toxicology, such as features, characterization, applications, environmental routes for dispersion, nanotoxicity, ecotoxicity and genotoxicity of nanomaterials, with emphasis on radiation toxicology, polar ecotoxicology, plastic toxicology, microbrial toxicology, nanotoxicology and pesticide toxicology. Also discussed is the use of microbes and nanotechnology for medicinal purposes, which has revealed important chemical prototypes in the discovery of new agents, stimulating the use of refined physical techniques and new syntheses of molecules with pharmaceutical applications for human welfare. The chapters also address the fate of nanoparticles in the environment, as well as nanotoxicology mechanisms impacting human health. The book will be of interest to toxicologists, environmental scientists, chemists, and students of microbiology, nanotechnology and pharmacology.

Chemical Warfare Toxicology

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Publisher : Royal Society of Chemistry
ISBN 13 : 178262807X
Total Pages : 346 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Chemical Warfare Toxicology by : Franz Worek

Download or read book Chemical Warfare Toxicology written by Franz Worek and published by Royal Society of Chemistry. This book was released on 2016-05-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focussing on the most important representative nerve and blistering agents, whilst also covering other potential chemical warfare agents, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure.

Symposium on Prophylaxis and Treatment of Organophosphate Poisoning

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Author :
Publisher :
ISBN 13 :
Total Pages : 125 pages
Book Rating : 4.:/5 (248 download)

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Book Synopsis Symposium on Prophylaxis and Treatment of Organophosphate Poisoning by : Symposium on Prophylaxis and Treatment of Organophosphate Poisoning

Download or read book Symposium on Prophylaxis and Treatment of Organophosphate Poisoning written by Symposium on Prophylaxis and Treatment of Organophosphate Poisoning and published by . This book was released on 1981 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicology of Insecticides

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Publisher : Springer Science & Business Media
ISBN 13 : 1461324912
Total Pages : 612 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Toxicology of Insecticides by : Fumio Matusmura

Download or read book Toxicology of Insecticides written by Fumio Matusmura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most rewarding aspect of writing a book is receiving encouraging comments from one's colleagues, since one always wonders whether fair coverage was made of the work of others or whether some omissions were made. I feel very fortunate that many colleagues took the time to read the first edition of this book and chose to use it as a textbook in their teaching. During the past few years they have given me valuable suggestions by pointing out areas that needed to be added to improve the book. Toxicology is one of the fastest moving scientific fields. In the areas of insecticide toxicology many new advances have been made since this treatise first appeared. Therefore, it would not be easy to write even a review paper that would not be outdated by the time it was published. In revising this volume I have made a conscious effort to adhere to the basic principles which have been developed over the years. While I have retained the basic framework of the original book, advances that fundamentally change certain concepts or add a new horizon have been chosen for updating those fields where applicable. The main emphasis has been placed on the addition of new sections and new compounds developed since 1975. Since the first edition appeared, several books covering technical details in each group have been published. They are excellent encyclopedic resources in their chosen areas, and are listed in each section as recommended reading material.

Disorders of Thrombosis and Hemostasis

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780397516902
Total Pages : 472 pages
Book Rating : 4.5/5 (169 download)

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Book Synopsis Disorders of Thrombosis and Hemostasis by : Rodger L. Bick

Download or read book Disorders of Thrombosis and Hemostasis written by Rodger L. Bick and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for a multidisciplinary audience, this revision presents current data on antithrombotic therapy including warfarins and heparin, delivers practical techniques for diagnosing and treating bleeding and clotting disorders, and includes all topics necessary for board review. This practical text covers disorders of thrombosis and hemostasis in a logical and sequential manner: etiology, pathophysiology, clinical and laboratory diagnosis, and management. Also included are diagnostic tests for deep venous thrombosis, three new clotting defects, hereditary disorders and defects, liver and renal diseases, cardiovascular events, and problems in obstetrical/gynecological patients. A Brandon-Hill recommended title.

Recognition and Management of Pesticide Poisonings

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Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Recognition and Management of Pesticide Poisonings by : Donald P. Morgan

Download or read book Recognition and Management of Pesticide Poisonings written by Donald P. Morgan and published by . This book was released on 1977 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pesticide Poisonings Handbook

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Publisher :
ISBN 13 :
Total Pages : 230 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Pesticide Poisonings Handbook by : Donald P. Morgan

Download or read book Pesticide Poisonings Handbook written by Donald P. Morgan and published by . This book was released on 1989 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Molecular Toxicology

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Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128084987
Total Pages : 30 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Advances in Molecular Toxicology by : Sigeng Chen

Download or read book Advances in Molecular Toxicology written by Sigeng Chen and published by Elsevier Inc. Chapters. This book was released on 2013-08-12 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphate (OP) exposure continues to be a threat to both civilian and military personnel. Sensitive and specific methods for the detection and remediation are needed not only for public health but also for farmers who are exposed to OPs frequently. Although detection approaches based on a mass spectrometry are sensitive and reliable, they require expensive equipment and expert operators. In addition, instrumentation such as mass spectrometer cannot be easily deployed in the field. Attempts to make point-of-care approaches have been the trend in both detecting and rescuing OP exposure in the current research of OP toxicity. This chapter will discuss some recent progress reported concerning the immunodetection of OP exposure and improved antidote therapy in the remediation of OP exposure.