Toxicology And Carcinogenesis Studies Of Ethylene Glycol Cas No 107 21 1 In B6c3f1 Mice Technical Report Series No413 Us Dept Of Health And Human Services 1995

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Handbook of Carcinogenic Potency and Genotoxicity Databases

Author : Lois Swirsky Gold
Publisher : CRC Press
ISBN 13 : 9781439810644
Total Pages : 840 pages
Book Rating : 4.8/5 (16 download)

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Book Synopsis Handbook of Carcinogenic Potency and Genotoxicity Databases by : Lois Swirsky Gold

Download or read book Handbook of Carcinogenic Potency and Genotoxicity Databases written by Lois Swirsky Gold and published by CRC Press. This book was released on 1996-11-26 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique new reference contains the Carcinogenic Potency Database (CPDB), which analyzes results of decades of animal cancer tests, including all Technical Reports of the National Toxicology Program (NTP) and the general published literature. A guide to the literature of animal cancer tests, the CPDB includes references to each published experiment and never-before published analyses. For each of 5,000 long-term experiments on 1,300 chemicals, the user-friendly format includes data on the species, strain, and sex of the test animal; features of experimental protocol such as the route of administration, duration of dosing, dose levels, and duration of the experiment; histopathology and tumor incidence; the shape of the dose-response curve; published author's opinion about the carcinogenicity at each site; and reference to the original publication of the test results. In addition, a measure of carcinogenic potency, the TD50, its statistical significance and confidence limits, are given for each tumor site. An overview is provided of earlier publication updates, such as positivity rates, reproducibility, interspecies extrapolation, and ranking possible carcinogenic hazards. The book also includes a summary of the NTP genetic toxicity test results on 1,500 chemicals, which are referenced to the original publications, including the Salmonella (Ames) test, L5178Y mouse lymphoma cell mutation test, chromosome aberration and sister chromatid exchange tests in cultured Chinese hamster ovary cells, and the sex-linked recessive lethal mutation test in Drosophila melanogaster. An index with chemicals listed by CAS number allows cross referencing between the carcinogenicity and genotoxicity databases, making data easy to find.

Spacecraft Water Exposure Guidelines for Selected Contaminants

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309128382
Total Pages : 206 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Spacecraft Water Exposure Guidelines for Selected Contaminants by : National Research Council

Download or read book Spacecraft Water Exposure Guidelines for Selected Contaminants written by National Research Council and published by National Academies Press. This book was released on 2008-12-21 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: NASA maintains an active interest in the environmental conditions associated with living and working in spacecraft and identifying hazards that might adversely affect the health and well-being of crew members. Despite major engineering advances in controlling the spacecraft environment, some water and air contamination is inevitable. Several hundred chemical species are likely to be found in the closed environment of the spacecraft, and as the frequency, complexity, and duration of human space flight increase, identifying and understanding significant health hazards will become more complicated and more critical for the success of the missions. To protect space crews from contaminants in potable and hygiene water, NASA requested that the National Research Council NRC provide guidance on how to develop water exposure guidelines and subsequently review NASA's development of the exposure guidelines for specific chemicals. This book presents spacecraft water exposure guidelines (SWEGs) for antimony, benzene, ethylene glycol, methanol, methyl ethyl ketone, and propylene glycol.

Issues in Risk Assessment

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309047862
Total Pages : 375 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Issues in Risk Assessment by : National Research Council

Download or read book Issues in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.

Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics

Author : United States. Food and Drug Administration
Publisher :
ISBN 13 :
Total Pages : 124 pages
Book Rating : 4.:/5 (35 download)

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Book Synopsis Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics by : United States. Food and Drug Administration

Download or read book Appraisal of the Safety of Chemicals in Foods, Drugs, and Cosmetics written by United States. Food and Drug Administration and published by . This book was released on 1959 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Profile for Ethylene Glycol

Author :
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Toxicological Profile for Ethylene Glycol by :

Download or read book Toxicological Profile for Ethylene Glycol written by and published by . This book was released on 2010 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

National Toxicology Program Annual Report for Fiscal Year ...

Author : National Toxicology Program (U.S.)
Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.:/5 (7 download)

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Book Synopsis National Toxicology Program Annual Report for Fiscal Year ... by : National Toxicology Program (U.S.)

Download or read book National Toxicology Program Annual Report for Fiscal Year ... written by National Toxicology Program (U.S.) and published by . This book was released on 1991 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (feed Studies)

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Author :
Publisher :
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (772 download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (feed Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (feed Studies) written by and published by . This book was released on 2000 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol (CAS No. 107-19-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

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Author : J. J. Butler
Publisher :
ISBN 13 : 9781437910681
Total Pages : 172 pages
Book Rating : 4.9/5 (16 download)

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Book Synopsis Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol (CAS No. 107-19-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) by : J. J. Butler

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol (CAS No. 107-19-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) written by J. J. Butler and published by . This book was released on 2009-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Propargyl alcohol is a commercially available acetylenic primary alcohol. It is used in a variety of chemical manufacturing processes and to protect steel from becoming brittle. The researchers studied propargyl alcohol to determine if it caused cancer in rats or mice. All groups of animals exposed to propargyl alcohol experienced a variety of lesions in the epithelial tissues of the nose, including hyperplase, metaplasia, and inflammation. Adenomas of the respiratory epithelium of the nose were observed in male rats and in male and female mice exposed to propargyl alcohol. The rate of mononuclear cell leukemia was also increased in exposed male rats, and the rate of Harderian gland edenomas was increased in exposed male mice. Illus.

Toxicity Studies of Hexachloro-1,3-butadiene in B6C3F1 Mice (feed Studies)

Author : Raymond Shih-hsien Yang
Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Toxicity Studies of Hexachloro-1,3-butadiene in B6C3F1 Mice (feed Studies) by : Raymond Shih-hsien Yang

Download or read book Toxicity Studies of Hexachloro-1,3-butadiene in B6C3F1 Mice (feed Studies) written by Raymond Shih-hsien Yang and published by . This book was released on 1991 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

National Toxicology Program

Author : National Toxicology Program (U.S.)
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis National Toxicology Program by : National Toxicology Program (U.S.)

Download or read book National Toxicology Program written by National Toxicology Program (U.S.) and published by . This book was released on 1987 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,2-bis(bromomethyl)-1,3-propanediol (FR-1138) (CAS No. 3296-90-0) in F344/N Rats and B6C3F1 Mice (feed Studies)

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Author :
Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,2-bis(bromomethyl)-1,3-propanediol (FR-1138) (CAS No. 3296-90-0) in F344/N Rats and B6C3F1 Mice (feed Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,2-bis(bromomethyl)-1,3-propanediol (FR-1138) (CAS No. 3296-90-0) in F344/N Rats and B6C3F1 Mice (feed Studies) written by and published by . This book was released on 1996 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: