Author : K. Barry Delclos
Publisher : DIANE Publishing
ISBN 13 : 1428988807
Total Pages : 320 pages
Book Rating : 4.4/5 (289 download)
Book Synopsis Toxicity Report on Reproductive Dose Range-Finding Study of Genistein (CAS No. 446-72-0) Administered in Feed to Sprague-Dawley Rats by : K. Barry Delclos
Download or read book Toxicity Report on Reproductive Dose Range-Finding Study of Genistein (CAS No. 446-72-0) Administered in Feed to Sprague-Dawley Rats written by K. Barry Delclos and published by DIANE Publishing. This book was released on 2008-04 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genistein is a naturally occurring isoflavone that interacts with estrogen receptors & multiple other molecular targets. Human exposure to Genistein is through consumption of soy products, including soy-based infant formula & dietary supplements. A series of short-term studies with Genistein was conducted with two goals: to obtain data necessary to establish dose levels for subsequent multi-generation reproductive & chronic toxicity studies; & to evaluate the effects of Genistein on endpoints outside the reproductive tract. This report focuses on the reproductive & toxicology endpoints. Data obtained in separate evaluations of behavioral, neuroanatomical, neurochemical, & immunological endpoints are also discussed. Illustrations.