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Tissue Engineering Of The Peripheral Nerve Biomaterials And Physical Therapy
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Book Synopsis Tissue Engineering of the Peripheral Nerve: Biomaterials and Physical Therapy by :
Download or read book Tissue Engineering of the Peripheral Nerve: Biomaterials and Physical Therapy written by and published by Academic Press. This book was released on 2013-10-01 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. This volume covers the cutting-edge research on tissue engineering of the peripheral nerve
Book Synopsis Central Nervous System Tissue Engineering by : A. Wilkinson
Download or read book Central Nervous System Tissue Engineering written by A. Wilkinson and published by Springer Nature. This book was released on 2022-06-01 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks
Book Synopsis Tissue Engineering of the Peripheral Nerve by :
Download or read book Tissue Engineering of the Peripheral Nerve written by and published by Academic Press. This book was released on 2013-09-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. This volume of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery
Book Synopsis Peripheral Nerve Tissue Engineering and Regeneration by : James B. Phillips
Download or read book Peripheral Nerve Tissue Engineering and Regeneration written by James B. Phillips and published by Springer. This book was released on 2022-05-26 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updatable book provides an accessible informative overview of the current state of the art in nerve repair research.The introduction includes history of nerve repair research and establishes key concepts and terminology and will be followed by sections that represent the main areas of interest in the field: (1) Biomaterials, (2) Therapeutic Cells, (3) Drug, Gene and Extracellular Vesicle Therapies, (4) Research Models and (5) Clinical Translation. Each section will contain 3 - 6 chapters, capturing the full breadth of relevant technology. Bringing together diverse disciplines under one overarching theme echoes the multidisciplinary approach that underpins modern tissue engineering and regenerative medicine. Each chapter will be written in an accessible manner that will facilitate interest and understanding, providing a comprehensive single reference source. The updatable nature of the work will ensure that it can evolve to accommodate future changes and new technologies. The main readership for this work will be researchers and clinicians based in academic, industrial and healthcare settings all over the world.
Book Synopsis Central Nervous System Tissue Engineering by : A. E. Wilkinson
Download or read book Central Nervous System Tissue Engineering written by A. E. Wilkinson and published by Morgan & Claypool Publishers. This book was released on 2011-11-11 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks
Book Synopsis Biomaterials for Neural Tissue Engineering by : Oguzhan Gunduz
Download or read book Biomaterials for Neural Tissue Engineering written by Oguzhan Gunduz and published by Elsevier. This book was released on 2023-04-18 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Neural Tissue Engineering covers a range of materials and technologies used for regenerating or repairing neural tissue. With a strong focus on biomaterials and scaffolds, the book examines the testing and evaluation pathway for in-vitro and in-vivo testing trials. This book introduces the reader to the fundamentals of the nervous system from a tissue engineering perspective and goes on to describe contemporary technologies used in the development of neural repair materials, as well as currently available biomaterials suitable for neural tissue repair and regeneration. This detailed reference is ideal for those who are new to using biomaterials in tissue engineering, particularly those interested in the nervous system, including academics and early career researchers in the fields of materials science, regenerative medicine, biomedical engineering and clinical sciences. Provides readers entering the field with a core introduction to neural tissue engineering processes and real-world applications Comprehensively examines a variety of biomaterial approaches Discusses the most current in-vitro and in-vivo testing and their importance in treating nervous system disorders Details a broad range of natural and synthetic biomaterials used to engineer neural tissue
Book Synopsis Engineering Neural Tissue from Stem Cells by : Stephanie Willerth
Download or read book Engineering Neural Tissue from Stem Cells written by Stephanie Willerth and published by Academic Press. This book was released on 2017-07-05 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications. Provides readers entering the field with a strong basis of neural tissue engineering processes and real-world applications Discusses the most current clinical trials and their importance of treating nervous system disorders Reviews the structure and immune response of the nervous system, including the brain, spinal cord and their present cells Offers a necessary overview of the natural and synthetic biomaterials used to engineer neural tissue
Book Synopsis Bioinspired Biomaterials by : Heung Jae Chun
Download or read book Bioinspired Biomaterials written by Heung Jae Chun and published by Springer Nature. This book was released on 2020-06-29 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. Topics addressed in this volume, which is devoted to bioinspired biomaterials, range from novel biomaterials for regenerative medicine through to emerging enabling technologies with applications in, for example, drug delivery, maternal–fetal medicine, peripheral nerve repair and regeneration, and brain tumor therapy. New bioinspired hydrogels receive detailed attention in the book, and a further focus is the use of bioinspired biomaterials in the regulation of stem cell fate. Here the coverage includes the role of scaffolds in cartilage regeneration, the bioapplication of inorganic nanomaterials in tissue engineering, and guidance of cell migration to improve tissue regeneration. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.
Book Synopsis Peripheral Nerve Regeneration by : Giovanna Gambarotta
Download or read book Peripheral Nerve Regeneration written by Giovanna Gambarotta and published by Frontiers Media SA. This book was released on 2019-12-24 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biologically Responsive Biomaterials for Tissue Engineering by : Iulian Antoniac
Download or read book Biologically Responsive Biomaterials for Tissue Engineering written by Iulian Antoniac and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in the area of biomaterials, bionanotechnology, tissue engineering, and medical devices are becoming the core of health care. Almost all medical specialties involve the use of biomaterials, and research plays a key role in the development of new and improved treatment modalities. This volume focuses on several current trends in tissue engineering, remodelling and regeneration. Leading researchers describe the use of nanomaterials to create new functionalities when interfaced with biological molecules or structures. In addition to coverage of basic science and engineering aspects, a range of applications in bionanotechnology are presented, including diagnostic devices, contrast agents, analytical tools, physical therapy applications, and vehicles for targeted drug delivery. The use of polymers, alloys, and composites, or a combination of these, for biomaterials applications in orthopaedics is also explored. These contributions represent essential reading for the biomaterials and biomedical engineering communities, and can serve as instructional course lectures targeted at graduate and post-graduate students.
Book Synopsis Scaffolds for Peripheral Nerve Regeneration, the Importance of In Vitro and In Vivo Studies for the Development of Cell-Based Therapies and Biomaterials: State of the Art by : Sílvia Santos Pedrosa
Download or read book Scaffolds for Peripheral Nerve Regeneration, the Importance of In Vitro and In Vivo Studies for the Development of Cell-Based Therapies and Biomaterials: State of the Art written by Sílvia Santos Pedrosa and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Human adult peripheral nerve injuries are a high incidence clinical problem that greatly affects patients' quality of life. Although peripheral nervous system has intrinsic regenerative capacity, this occurs in an incomplete or poorly functional manner. When a nerve fiber loses its continuity with consequent damage of the basal lamina tubes, axon spontaneous regeneration is disorganized and mismatched. These phenomena translate in an inadequate nerve functional recovery and consequent musculoskeletal incapacity. Nerve grafts still remain the gold standard in peripheral injuries treatment. However, this approach contains its disadvantages such as the necessity of primary surgery to harvest the autografts, loss of a functional nerve, donor site morbidity and longer surgery procedures. Therefore, biomaterials and tissue engineering can provide efficient resources and alternatives to nerve injury repair not only by the development of biocompatible structures but also, introducing neurotrophic factors and cellular systems to stimulate optimum clinical outcome. In this chapter, a comprehensive state-of-the art picture of tissue-engineered nerve grafts scaffolds, their application in nerve regeneration along with latest advances in peripheral nerve repair and future perspectives will be discussed, including our own large experience in this field of knowledge.
Book Synopsis Neural Engineering by : Lijie Grace Zhang
Download or read book Neural Engineering written by Lijie Grace Zhang and published by Springer. This book was released on 2016-06-29 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the principles of advanced 3D fabrication techniques, stem cells and biomaterials for neural engineering. Renowned contributors cover topics such as neural tissue regeneration, peripheral and central nervous system repair, brain-machine interfaces and in vitro nervous system modeling. Within these areas, focus remains on exciting and emerging technologies such as highly developed neuroprostheses and the communication channels between the brain and prostheses, enabling technologies that are beneficial for development of therapeutic interventions, advanced fabrication techniques such as 3D bioprinting, photolithography, microfluidics, and subtractive fabrication, and the engineering of implantable neural grafts.There is a strong focus on stem cells and 3D bioprinting technologies throughout the book, including working with embryonic, fetal, neonatal, and adult stem cells and a variety of sophisticated 3D bioprinting methods for neural engineering applications. There is also a strong focus on biomaterials, including various conductive biomaterials and biomimetic nanomaterials such as carbon-based nanomaterials and engineered 3D nanofibrous scaffolds for neural tissue regeneration. Finally, two chapters on in vitro nervous system models are also included, which cover this topic in the context of studying physiology and pathology of the human nervous system, and for use in drug discovery research. This is an essential book for biomedical engineers, neuroscientists, neurophysiologists, and industry professionals.
Book Synopsis Tissue Engineering for the Hand by : James Chang
Download or read book Tissue Engineering for the Hand written by James Chang and published by World Scientific. This book was released on 2010 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Musculoskeletal applications of tissue engineering will be among the first to achieve widespread clinical use, and the resulting shift in clinical and surgical paradigms will highlight the need for an authoritative text on tissue engineering for musculoskeletal tissues including nerve, bone, tendon, skin, vessels, and cartilage. This book will serve the needs of a large readership including plastic surgeons, orthopedic surgeons, medical residents and medical students, researchers and academic faculty in regenerative medicine and biomedical engineering, and medical device experts. This textbook will serve as the curriculum for undergraduate and graduate courses in biomedical engineering and surgery. Notable contributors to this volume include Antonios G Mikos, PhD; Wei Liu, MD; Yilin Cao, MD; Mark Randolph, MAS; Jennifer Elisseeff, PhD; Geoffrey C Gurtner, MD; Michael T Longaker, MD; and James Chang, MD, all of whom are leaders in tissue engineering research and applications.
Book Synopsis Tissue Engineering by : Clemens van Blitterswijk
Download or read book Tissue Engineering written by Clemens van Blitterswijk and published by Academic Press. This book was released on 2014-12-10 with total page 891 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering
Book Synopsis Biomaterials Science by : William Wagner
Download or read book Biomaterials Science written by William Wagner and published by Academic Press. This book was released on 2020-01-04 with total page 1610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials Science: An Introduction to Materials in Medicine, Fourth Edition, is the most comprehensive text on biomaterials science, from principles to applications. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials, acting as a key reference for practitioners involved in the applications of materials in medicine. In this new edition, there are key updates to reflect the latest relevant research in the field, particularly in applications in nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Based on customer feedback, the new edition also features a consolidation of redundant material to ensure clarity and focus. Where appropriate, end-of-chapter exercises have been included with online solutions available.
Book Synopsis Biomaterials and Cellular Systems at the Forefront of Peripheral Nerve Regeneration by : Ana Colette Maurício
Download or read book Biomaterials and Cellular Systems at the Forefront of Peripheral Nerve Regeneration written by Ana Colette Maurício and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peripheral nerve injuries remain a common clinical complication, and currently available therapies present significant limitations, often resulting in poor and suboptimal outcomes. Despite significant developments in microsurgical approaches in the last decades, no effective treatment options have been disclosed. Current research focuses on the optimization of such microsurgical techniques and on their combination with other pro-regenerative factors, such as mesenchymal stem cells or biomaterials. Mesenchymal stem cells present a remarkable capacity for bioactive molecule production that modulates inflammatory and regenerative processes, stimulating peripheral nerve regeneration. In parallel, efforts have been directed towards the development of biomaterial nerve guidance channels and nerve conduits. These biomaterials have been optimized in terms of biodegradability, ability to release bioactive factors, incorporation of cellular agents, and internal matrix architecture (to enable cellular migration and mimic native tissue morphology and to generate and bear specific electrical activity). The current literature review presents relevant advances in the development of mesenchymal stem cell and biomaterial-based therapeutic approaches aiming at the peripheral nerve tissue regeneration in diverse lesion scenarios, also exploring the advances achieved by our research group in this field in recent years.
Book Synopsis Surgical Disorders of the Peripheral Nerves by : Rolfe Birch
Download or read book Surgical Disorders of the Peripheral Nerves written by Rolfe Birch and published by Springer Science & Business Media. This book was released on 2011-01-21 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the highly praised first edition of Surgical Disorders of the Peripheral Nerves was published in 1998, greater understanding of the the molecular and cellular events which underlie the response of nerves to injury, regeneration and neuropathic pain has been achieved. This second edition has been fully updated in line with new clinical knowledge, and also incorporates the extensive study of thousands of surgical case studies spanning repairs of the supraclavicular plexus in the adult, the birth lesion of the brachial plexus,compound nerve injury and iatrogenous injury. Beginning with the fundamentals of the anatomy and function of the peripheral nervous system, and working its way through various types of injury, operative methods, the regeneration and recovery of nerves, surgical reconstruction, pain, and rehabilitation, this eloquently written work provides the reader with the solid understanding required to successfully perform surgery on the peripheral nervous system. Dr Shelagh Smith, joined by Dr Ravi Knight, has rewritten the chapter Electrodiagnosis. Professor Tara Renton has written a new chapter on injuries to the trigeminal nerve in maxilla-facial and dental work. The drawings, by Mr Philip Wilson, are new. Most of the 700 illustrations are also new. This thorough and authoritative look at the surgical treatment of the peripheral nerves is fully illustrated throughout with exquisite line diagrams and clear, instructive photographs.
