The Way Of Synthesis

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The Way of Synthesis

Author : Tomas Hudlicky
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis The Way of Synthesis by : Tomas Hudlicky

Download or read book The Way of Synthesis written by Tomas Hudlicky and published by Wiley-VCH. This book was released on 2007-09-04 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)

Classics in Total Synthesis

Author : K. C. Nicolaou
Publisher : John Wiley & Sons
ISBN 13 : 3527292314
Total Pages : 826 pages
Book Rating : 4.5/5 (272 download)

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Book Synopsis Classics in Total Synthesis by : K. C. Nicolaou

Download or read book Classics in Total Synthesis written by K. C. Nicolaou and published by John Wiley & Sons. This book was released on 1996-04-11 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alternative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information. Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.

Introduction to Strategies for Organic Synthesis

Author : Laurie S. Starkey
Publisher : John Wiley & Sons
ISBN 13 : 1118180852
Total Pages : 360 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Introduction to Strategies for Organic Synthesis by : Laurie S. Starkey

Download or read book Introduction to Strategies for Organic Synthesis written by Laurie S. Starkey and published by John Wiley & Sons. This book was released on 2012-01-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.

Organic Synthesis

Author : Michael Smith
Publisher : Academic Press
ISBN 13 : 1890661406
Total Pages : 1536 pages
Book Rating : 4.8/5 (96 download)

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Book Synopsis Organic Synthesis by : Michael Smith

Download or read book Organic Synthesis written by Michael Smith and published by Academic Press. This book was released on 2011-07-12 with total page 1536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.

Organic Chemistry

Author : Robert J. Ouellette
Publisher : Academic Press
ISBN 13 : 0128128399
Total Pages : 1058 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Organic Chemistry by : Robert J. Ouellette

Download or read book Organic Chemistry written by Robert J. Ouellette and published by Academic Press. This book was released on 2018-02-03 with total page 1058 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry: Structure, Mechanism, Synthesis, Second Edition, provides basic principles of this fascinating and challenging science, which lies at the interface of physical and biological sciences. Offering accessible language and engaging examples and illustrations, this valuable introduction for the in-depth chemistry course engages students and gives future and new scientists a new approach to understanding, rather than merely memorizing the key concepts underpinning this fundamental area. The book builds in a logical way from chemical bonding to resulting molecular structures, to the corresponding physical, chemical and biological properties of those molecules. The book explores how molecular structure determines reaction mechanisms, from the smallest to the largest molecules—which in turn determine strategies for organic synthesis. The book then describes the synthetic principles which extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, in which principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the theory and applications. Featuring in-book solutions and instructor PowerPoint slides, this Second Edition offers an updated and improved option for students in the two-semester course and for scientists who require a high quality introduction or refresher in the subject. - Offers improvements for the two-semester course sequence and valuable updates including two new chapters on lipids and nucleic acids - Features biochemistry and biological examples highlighted throughout the book, making the information relevant and engaging to readers of all backgrounds and interests - Includes a valuable and highly-praised chapter on organometallic chemistry not found in other standard references

Organic Synthesis

Author : Paul Wyatt
Publisher : John Wiley & Sons
ISBN 13 : 1118681444
Total Pages : 55 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Organic Synthesis by : Paul Wyatt

Download or read book Organic Synthesis written by Paul Wyatt and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Advanced Organic Synthesis

Author : Richard Monson
Publisher : Elsevier
ISBN 13 : 0323159974
Total Pages : 216 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Advanced Organic Synthesis by : Richard Monson

Download or read book Advanced Organic Synthesis written by Richard Monson and published by Elsevier. This book was released on 2012-12-02 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Organic Synthesis: Methods and Techniques presents a survey and systematic introduction to the modern techniques of organic synthesis. The book attempts to acquaint the reader with a variety of laboratory techniques as well as introduce chemical reagents that require deftness and care in handling. Chapters are devoted that discuss the techniques of organic synthesis; apparatus and terminology used in the description of synthetic procedures; the scope and mechanism of chemical reactions; and technical procedures on how to perform chemical experiments. The text will be of vital importance to advanced undergraduate student or beginning graduate student of chemistry.

Strategies for Organic Drug Synthesis and Design

Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 9780470399590
Total Pages : 700 pages
Book Rating : 4.3/5 (995 download)

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Book Synopsis Strategies for Organic Drug Synthesis and Design by : Daniel Lednicer

Download or read book Strategies for Organic Drug Synthesis and Design written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2009-03-04 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

Comprehensive Organic Synthesis

Author : Barry M. Trost
Publisher : Elsevier
ISBN 13 : 9780080405995
Total Pages : 1174 pages
Book Rating : 4.4/5 (59 download)

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Book Synopsis Comprehensive Organic Synthesis by : Barry M. Trost

Download or read book Comprehensive Organic Synthesis written by Barry M. Trost and published by Elsevier. This book was released on 1991 with total page 1174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 8.

Micro Reaction Technology in Organic Synthesis

Author : Charlotte Wiles
Publisher : CRC Press
ISBN 13 : 143982472X
Total Pages : 453 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Micro Reaction Technology in Organic Synthesis by : Charlotte Wiles

Download or read book Micro Reaction Technology in Organic Synthesis written by Charlotte Wiles and published by CRC Press. This book was released on 2016-04-19 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists c

Introduction to Strategies for Organic Synthesis

Author : Laurie S. Starkey
Publisher : John Wiley & Sons
ISBN 13 : 1119347246
Total Pages : 439 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Introduction to Strategies for Organic Synthesis by : Laurie S. Starkey

Download or read book Introduction to Strategies for Organic Synthesis written by Laurie S. Starkey and published by John Wiley & Sons. This book was released on 2018-05-01 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the Gap Between Organic Chemistry Fundamentals and Advanced Synthesis Problems Introduction to Strategies of Organic Synthesis bridges the knowledge gap between sophomore-level organic chemistry and senior-level or graduate-level synthesis to help students more easily adjust to a synthetic chemistry mindset. Beginning with a thorough review of reagents, functional groups, and their reactions, this book prepares students to progress into advanced synthetic strategies. Major reactions are presented from a mechanistic perspective and then again from a synthetic chemist’s point of view to help students shift their thought patterns and teach them how to imagine the series of reactions needed to reach a desired target molecule. Success in organic synthesis requires not only familiarity with common reagents and functional group interconversions, but also a deep understanding of functional group behavior and reactivity. This book provides clear explanations of such reactivities and explicitly teaches students how to make logical disconnections of a target molecule. This new Second Edition of Introduction to Strategies for Organic Synthesis: Reviews fundamental organic chemistry concepts including functional group transformations, reagents, stereochemistry, and mechanisms Explores advanced topics including protective groups, synthetic equivalents, and transition-metal mediated coupling reactions Helps students envision forward reactions and backwards disconnections as a matter of routine Gives students confidence in performing retrosynthetic analyses of target molecules Includes fully-worked examples, literature-based problems, and over 450 chapter problems with detailed solutions Provides clear explanations in easy-to-follow, student-friendly language Focuses on the strategies of organic synthesis rather than a catalogue of reactions and modern reagents The prospect of organic synthesis can be daunting at the outset, but this book serves as a useful stepping stone to refresh existing knowledge of organic chemistry while introducing the general strategies of synthesis. Useful as both a textbook and a bench reference, this text provides value to graduate and advanced undergraduate students alike.

Strategic Applications of Named Reactions in Organic Synthesis

Author : Laszlo Kurti
Publisher : Elsevier
ISBN 13 : 0080575412
Total Pages : 808 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Strategic Applications of Named Reactions in Organic Synthesis by : Laszlo Kurti

Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings

An Introduction to Drug Synthesis

Author : Graham L. Patrick
Publisher : Oxford University Press, USA
ISBN 13 : 0198708432
Total Pages : 587 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis An Introduction to Drug Synthesis by : Graham L. Patrick

Download or read book An Introduction to Drug Synthesis written by Graham L. Patrick and published by Oxford University Press, USA. This book was released on 2015 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

Modern Organic Synthesis

Author : George S. Zweifel
Publisher : John Wiley & Sons
ISBN 13 : 1119086760
Total Pages : 416 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Modern Organic Synthesis by : George S. Zweifel

Download or read book Modern Organic Synthesis written by George S. Zweifel and published by John Wiley & Sons. This book was released on 2017-03-13 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between sophomore and advanced / graduate level organic chemistry courses, providing students with a necessary background to begin research in either an industry or academic environment. • Covers key concepts that include retrosynthesis, conformational analysis, and functional group transformations as well as presents the latest developments in organometallic chemistry and C–C bond formation • Uses a concise and easy-to-read style, with many illustrated examples • Updates material, examples, and references from the first edition • Adds coverage of organocatalysts and organometallic reagents

The Synthesis Effect

Author : John McGrail
Publisher : Red Wheel/Weiser
ISBN 13 : 1601636121
Total Pages : 240 pages
Book Rating : 4.6/5 (16 download)

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Book Synopsis The Synthesis Effect by : John McGrail

Download or read book The Synthesis Effect written by John McGrail and published by Red Wheel/Weiser. This book was released on 2012-03-22 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: For far too many of us, modern life is a struggle. We are stressed, depressed, anxious, addicted, obese, terrified, and angry. Are we doomed to live this way? Dr. John McGrail answers with an emphatic: “No. Anyone and everyone can create the life of their dreams.” In The Synthesis Effect he shows you how, sharing his unique process in an engaging, friendly narrative that includes stories of real people overcoming real issues and empowering their lives quickly and profoundly. The Synthesis Effect will show you: How you became you—your personality, values, feelings, habits, beliefs, and behaviors—how you create your own reality, and why it’s so difficult to change it. That you already have everything you need within you to change and transform your life, and how to use the models, tools, techniques, and exercises of Synthesis to do so. How to reach “practical enlightenment,” living your life virtually free of suffering...and how to pass it on to others. The Synthesis Effect provides simple, powerful, and clinically proven techniques for creating personal change and transformation while outlining a realistic roadmap to help us rediscover our power, save ourselves, and save our planet.

Enantioselective Chemical Synthesis

Author : Elias J. Corey
Publisher :
ISBN 13 : 9781306070645
Total Pages : 328 pages
Book Rating : 4.0/5 (76 download)

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Book Synopsis Enantioselective Chemical Synthesis by : Elias J. Corey

Download or read book Enantioselective Chemical Synthesis written by Elias J. Corey and published by . This book was released on 2013 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field s progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource. In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists. Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level. Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules Clearly explains stereochemical synthesis in theory and practiceProvides a handy tool box for scientists wishing to understand and apply chiral chemical synthesisDescribes almost 50 real life examples of asymmetric synthesis in practice and examines how the chiral centers were introduced at key synthetic stages"

Classics in Stereoselective Synthesis

Author : Erick M. Carreira
Publisher : John Wiley & Sons
ISBN 13 : 9783527324521
Total Pages : 664 pages
Book Rating : 4.3/5 (245 download)

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Book Synopsis Classics in Stereoselective Synthesis by : Erick M. Carreira

Download or read book Classics in Stereoselective Synthesis written by Erick M. Carreira and published by John Wiley & Sons. This book was released on 2009-02-09 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.