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The Thymus In Immunotoxicology
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Book Synopsis The Thymus in Immunotoxicology by : Marion D. Kendall
Download or read book The Thymus in Immunotoxicology written by Marion D. Kendall and published by CRC Press. This book was released on 1991 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Thymus Update 4" details the sensitivity of the thymus to xenobiotics and their effects on thymocyte development and maturation. It highlights the importance of immunological testing of all envoronmental toxins, such as dioxin, tin compounds and caramel additives, and drugs, such as immunosuppressives, antiviral agents and antihypertensive agents. The effects of trauma are also considered. Part two covers a subject of topical importance: an update on procedures for vascular transplantation of the thymus.
Download or read book Thymus written by Nima Rezaei and published by BoD – Books on Demand. This book was released on 2020-01-29 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thymus gland is highly valuable, due to its functions as a part of the neuroendocrine system as well as its actions to provide a primary lymphoid microenvironment that efficiently carries T-cell differentiation and selection. This book begins with an introduction and explanation of the development of the thymus. Subsequent chapters examine a range of conditions - including environmental pollution, congenital anomalies, autoimmune diseases, and malignancies - that threaten the function and development of the thymus. The information presented herein is useful for a wide range of readers across a variety of specialties.
Book Synopsis Immunoregulatory Role of Thymus by : Marek P. Dabrowski
Download or read book Immunoregulatory Role of Thymus written by Marek P. Dabrowski and published by CRC Press. This book was released on 2019-06-04 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1990. This important new text covers a wide area of thymology in both the theoretical and practical aspects. In view of current information, a crucial role of endocrine thymus is presented in the creation, maintenance, and senescence of neuro-endocrine-immune homeostasis. In particular, mechanisms are described (which are basically responsible for the T cell maturation and selection) for the hierarchic organization of the immune system and its thymic dependent immune competence in terms of tolerance and immunity. A detailed presentation of the structure and biological properties of a number of well-defined thymic hormones is included. Their clinical applications and results obtained in inherited or acquired immunodeficiencies and in neoplasmic diseases are also reviewed on the grounds of numerous representative clinical trials. A perspective and potential scope of immunorestorative therapy and prevention with thymic hormones and other thymomimetic drugs are outlined. Researchers, practitioners, and students will find this book to be a useful and essential source of information.
Author :The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety Publisher :Springer Science & Business Media ISBN 13 :9400943075 Total Pages :522 pages Book Rating :4.4/5 (9 download)
Book Synopsis Immunotoxicology by : The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety
Download or read book Immunotoxicology written by The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: IX The International Seminar on the Immunological System as a Target for Toxic Damage was held at The Commission of the European Communities (CEC) in Luxembourg on 6-9 November 1984. It was organized by the CEC and the International Programme on Chemical Safety of UNEP/ILO/WHO with the support of the u. S. Environmental Protection Agency and the National Institute of Environmental Health Sciences - USA and with the participation of the International Society of Immunophar macology. These bodies are actively concerned with the scientific and applied aspects of immunotoxicology. The Seminar consisted of thirty-four invited papers and three major panel discussions covering current and future test strategies for the screening of immunotoxic substances, hypersensitivity and the health implications of immunotoxico logical problems. It was attended by more than 200 scien tists from 27 countries representing all the Member states of the European Economic Community and the six Regions of the World Health Organization. These scientists represented many different disciplines and interests. The Seminar's principal objectives were: a review of recent advances in knowledge concerning the structure, function and dysfunction of the immunological system; - a review of the effects of xenobiotics on the immune system in animals and humans; an examination of the human health implications of immunotoxicity; discussion and critical analysis of the procedures for the assessment of immunological damage, a discussion of needs for the further development of laboratory and epidemiological methods and their validation, and a consideration of current test strategies.
Book Synopsis Investigative Immunotoxicology by : Helen Tryphonas
Download or read book Investigative Immunotoxicology written by Helen Tryphonas and published by CRC Press. This book was released on 2005-01-27 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigative Immunotoxicology provides a critical evaluation of proposed experimental animal models and approaches, and discusses the contribution that immunotoxicity can make to the overall assessment of chemical-induced adverse health effects on humans and the ecosystem. Following a review of general concepts in immunotoxicology, the book discus
Book Synopsis T Lymphocytes Subpopulations in Immunotoxicology by : Ian Kimber
Download or read book T Lymphocytes Subpopulations in Immunotoxicology written by Ian Kimber and published by John Wiley & Sons. This book was released on 1998-08-17 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Den T-Lymphocyten kommt eine Schlüsselrolle im Immunsystem zu: Sie sind unter anderem für Resistenzen gegenüber Infektionen und Tumoren und für die Entwicklung von Allergien und Autoimmunität verantwortlich. Bisher gab es kein vergleichbares Buch, das Funktionen und Subpopulationen der T-Zellen wie das vorliegende Werk von immunbiologischen Grundlagen ausgehend zusammenfassend darstellt.(05/98)
Author :H.K. Müller-Hermelink Publisher :Springer Science & Business Media ISBN 13 :3642824803 Total Pages :420 pages Book Rating :4.6/5 (428 download)
Book Synopsis The Human Thymus by : H.K. Müller-Hermelink
Download or read book The Human Thymus written by H.K. Müller-Hermelink and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty-five years have passed since J. MILLER'S basic work on the central role of the thymus for the generation of immunological reactivi ty. During this time, the abundance of fascinating literature on the immunological and functional aspects of this organ has been in contrast to the paucity of reports on its role in pathology. The causal or formal pathogenesis even of many of the well-documented pathological fea tures is so far unexplained or at least uncertain. In spite of some concep tual progress related to the work of CASTLEMAN, LEVINE, and ROSAI, we regrettably have to say that in pathology the thymus remains almost as inconspicuous as 25 years ago. Only the new techniques developed in recent years have made it possible to look as closely into the complicated structural organization of the thymus as it appears to be necessary to observe and document abnormalities. Major steps have been taken with the advent of mono clonal antibody immune histochemistry and with detailed ultrastructur al studies in embryology. At this point, pathologists and researchers with a special interest in the thymus were asked to give overviews of their respective fields of interest in light of recent findings in immunology and basic insights into the structural-functional interrelationship of the human thymus. The results of this initiative have been brought together in this volume.
Book Synopsis Immunotoxicity of Metals and Immunotoxicology by : International Program on Chemical Safety
Download or read book Immunotoxicity of Metals and Immunotoxicology written by International Program on Chemical Safety and published by Springer. This book was released on 1990-11-30 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considerable scientific and political interest has been expressed, parallelling public concern about the effects of chemicals on the immune system and the implications of those effects for health. Coupled with speculation about the magnitude and extent of the problem is discussion of needs for predictive testing and regulatory control measures. The first international seminar on the immunological system as a target for toxic damage was held in Luxembourg in 1984. It was organized by the International Programme on Chemical Safety (United Nations Environment Programme-International Labour Office World Health Organization) and the Commission of the European Communities with the support of the US Environmental Protection Agency and the National Institute of Environmental Health Sciences (USA) and the participation of the International Society of Immunopharmacology. In view of the perceived importance of imrnunotoxicity, it was considered necessary to organize a follow-up meeting. Thus, an international workshop on the immunotoxicity of metals and immuno toxicology was held in Hanover, Federal Republic of Germany, on 6-10 November 1989.
Book Synopsis Molecular Immunotoxicology by : Emanuela Corsini
Download or read book Molecular Immunotoxicology written by Emanuela Corsini and published by John Wiley & Sons. This book was released on 2014-11-24 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human immune system is constantly exposed to chemical contaminants, whether from food, water or air. Some chemicals directly elicit an immune response, while others indirectly activate or deactivate components within the immune system. Thus when tracking or predicting the effect of a chemical on the immune system, many different pathways and modes of action need to be considered. Following an introduction to the various pathways and toxicity mechanisms from a systemic perspective, the main part of this comprehensive reference surveys individual molecular mechanisms of important immunotoxicants, from PAHs to biopharmaceuticals, and from receptor-mediated toxicity to nanoparticle toxicity, using analyses based on molecular effects rather than on animal models. Taken together, the knowledge presented here provides an up-to-date overview of this hot topic that can be directly applied to the prediction and characterization of immunotoxic effects in drugs, chemicals, and environmental contaminants.
Book Synopsis Experimental Immunotoxicology by : Ralph J. Smialowicz
Download or read book Experimental Immunotoxicology written by Ralph J. Smialowicz and published by CRC Press. This book was released on 1996 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunotoxicology has emerged as a vital and expanding discipline over the past several years. Although the field of human immunotoxicology is arguably still in its infancy, a number of animal model systems have been well established and validated. Experimental Immunotoxicology provides an update on the recent advances in the field as it relates to animals and provokes discussion on approaches to the evaluation of human immunotoxicology. It is an important reference source for professionals in immunology and toxicology. The book begins with an overview of the mammalian immune system and covers the important role played by animal host susceptibility models. It also gives an update on immunotoxicolgy in sub-human primates. Vulnerability of bone marrow and the consequences of damage to immune function as well as chemical-induced immunosuppression as a consequence of exposure to chemicals are covered. Most of the chapters are organized to include a description of the profile of immunotoxicity, mechanisms of immunotoxicity, species comparisons and research needs.
Book Synopsis Developmental Immunotoxicology by : Steven D. Holladay
Download or read book Developmental Immunotoxicology written by Steven D. Holladay and published by CRC Press. This book was released on 2004-11-15 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment. This text describes different models used to study developmental immunotoxicology and examples of specific developmental immunotoxic agents, including therapeutics. The text concludes with several chapters that describe the role of neuroimmune interactions as they relate to developmental immunotoxicology. Using a didactic approach, Developmental Immunotoxicology provides an explanatory overview of this cutting-edge field for toxicologists, immunologists, and developmental biologists. It provides a lucid account of this area of research-proposing answers to some questions and stimulating debate on those questions yet to be addressed by the research community.
Download or read book NIH Immunotoxicology Workshop written by and published by . This book was released on 1985 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunotoxicology and Immunopharmacology by : Robert V. House
Download or read book Immunotoxicology and Immunopharmacology written by Robert V. House and published by CRC Press. This book was released on 2006-12-26 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history,
Book Synopsis Principles and Methods of Immunotoxicology by : Jacques Descotes
Download or read book Principles and Methods of Immunotoxicology written by Jacques Descotes and published by Elsevier. This book was released on 2004-10-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.
Book Synopsis Immunotoxicology of Drugs and Chemicals by : Jacques Descotes
Download or read book Immunotoxicology of Drugs and Chemicals written by Jacques Descotes and published by Elsevier Publishing Company. This book was released on 1986 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis T Lymphocytes Subpopulations in Immunotoxicology by : Ian Kimber
Download or read book T Lymphocytes Subpopulations in Immunotoxicology written by Ian Kimber and published by Wiley. This book was released on 1998-08-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Den T-Lymphocyten kommt eine Schlüsselrolle im Immunsystem zu: Sie sind unter anderem für Resistenzen gegenüber Infektionen und Tumoren und für die Entwicklung von Allergien und Autoimmunität verantwortlich. Bisher gab es kein vergleichbares Buch, das Funktionen und Subpopulationen der T-Zellen wie das vorliegende Werk von immunbiologischen Grundlagen ausgehend zusammenfassend darstellt.(05/98)
Book Synopsis Introduction To Immunotoxicology by : Jacques Descotes
Download or read book Introduction To Immunotoxicology written by Jacques Descotes and published by CRC Press. This book was released on 1998-12-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.
