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Author : Michael Balls
Publisher :
ISBN 13 : 9780950170022
Total Pages : 0 pages
Book Rating : 4.1/5 (7 download)
Download or read book The Three Rs and the Humanity Criterion written by Michael Balls and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Edward N. Eadie
Publisher : Springer Science & Business Media
ISBN 13 : 3642305768
Total Pages : 139 pages
Book Rating : 4.6/5 (423 download)
Download or read book Understanding Animal Welfare written by Edward N. Eadie and published by Springer Science & Business Media. This book was released on 2012-08-31 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the contents, influence, and potential of a personal selection of modern books published over the last fifty years that have been relevant to improving welfare. The works selected comprise three earlier classics that mainly deal with animal experimentation and intensive farming, as well as five that concentrate on specific subject areas, namely history, science, applied ethics, politics and law, that are important to protecting the welfare of animals against suffering inflicted by humans. The books are arranged in the order of their publication date, and for each one a few related works are also mentioned or discussed. This collection provides a broad understanding of animal protection issues, and provides the necessary basis for an informed and comprehensive approach to improving the welfare of animals. The books selected have been influential and they have the potential to improve animal welfare in the future.
Author :
Publisher : Academic Press
ISBN 13 : 0128136987
Total Pages : 352 pages
Book Rating : 4.1/5 (281 download)
Download or read book The History of Alternative Test Methods in Toxicology written by and published by Academic Press. This book was released on 2018-10-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.
Author : Mageshwaran Lakshmanan
Publisher : Springer Nature
ISBN 13 : 9811953430
Total Pages : 900 pages
Book Rating : 4.8/5 (119 download)
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Mageshwaran Lakshmanan and published by Springer Nature. This book was released on 2022-11-15 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is designed to impart the fundamental concepts in experimental pharmacology, research methodology and biostatistics. Through this book, the readers will learn about different methods involved in drug discovery, experimental animals and their care, equipments and the various bioassays used in experimental pharmacology. This book contains special sections on various drug screening methods involved in the evaluation of different body systems. Certain sections provide the healthcare professionals with the knowledge necessary to interpret clinical research articles, design clinical studies, and learn essential concepts in biostatistics in an expedient and concise manner. Basic principles and applications of simple analytical methods employed in drug analysis are well written under one section. It focuses on the basic and advanced laboratory techniques and also on computer simulated data, written extensively under the Biostatistics section. The methods used for drug analysis have been described in adequate detail with cross-references for further studies and comprehension. Overall, the book is designed systematically with four broad sections with extensive subdivisions for easy tracking, interpretation, and understanding.
Author : William Moy Stratton Russell
Publisher : Hyperion Books
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.U/5 (183 download)
Download or read book The Principles of Humane Experimental Technique written by William Moy Stratton Russell and published by Hyperion Books. This book was released on 1992 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kathryn Bayne
Publisher : Academic Press
ISBN 13 : 0123851041
Total Pages : 336 pages
Book Rating : 4.1/5 (238 download)
Download or read book Laboratory Animal Welfare written by Kathryn Bayne and published by Academic Press. This book was released on 2013-09-02 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.
Author : Antonio Peña-Fernández
Publisher : CRC Press
ISBN 13 : 1351398016
Total Pages : 531 pages
Book Rating : 4.3/5 (513 download)
Download or read book Toxicology for the Health and Pharmaceutical Sciences written by Antonio Peña-Fernández and published by CRC Press. This book was released on 2021-12-21 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry and in the public and private sectors. The study of toxicology is becoming increasingly relevant in human health sciences, as future health and clinical professionals will be pivotal in addressing and managing emerging chemical threats and hazards related to modern anthropogenic activities and technological development. Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, Toxicology for the Health and Pharmaceutical Sciences provides a concise yet comprehensive volume that can be used as a relevant textbook on toxicology for the clinical, healthcare, educational and professional sectors. Key Features: Includes cutting edge information regarding the very lastest environmental threats to public health Provides a detailed case study based on a real-world scenario that allows the reader to practice human health risk assessment Describes innovative guidance and tools to respond to chemical incidents and attacks, which enables the reader to tailor an effective protection and remediation response This book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats. Thus, this volume has chapters specifically designed to support the understanding of the most current toxicology-related subjects for any undergraduate/postgraduate health programs as well as aid the delivery of continuing professional development training on up-to-date topics in toxicology for current practicing health professionals wishing to improve their background knowledge in toxicology. The book is also vital reading and reference for policy makers and others that influence and set regulations that have an impact on the environment and human health.
Author : Oliver Kayser
Publisher : John Wiley & Sons
ISBN 13 : 352765125X
Total Pages : 677 pages
Book Rating : 4.5/5 (276 download)
Download or read book Pharmaceutical Biotechnology written by Oliver Kayser and published by John Wiley & Sons. This book was released on 2012-03-27 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.
Author : Kimberly Coates
Publisher : Enslow Publishing, LLC
ISBN 13 : 1978503849
Total Pages : 232 pages
Book Rating : 4.9/5 (785 download)
Download or read book Critical Perspectives on Animal Testing written by Kimberly Coates and published by Enslow Publishing, LLC. This book was released on 2019-07-15 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal testing is a controversial issue, with some arguing it is essential to medical advancement and others stating it is cruel and unnecessary. In this book, articles from a variety of viewpoints and individuals, including scientists, government and legal professionals, media outlets, and ordinary citizens, highlight key areas of contention over animal testing. Questions at the end of each article encourage readers to think critically about what they have read and to form their own opinions on this important issue.
Author : Hajime Kojima
Publisher : Springer
ISBN 13 : 9811324476
Total Pages : 130 pages
Book Rating : 4.8/5 (113 download)
Download or read book Alternatives to Animal Testing written by Hajime Kojima and published by Springer. This book was released on 2018-12-27 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
Author : David E. Newton
Publisher : Bloomsbury Publishing USA
ISBN 13 : 1610693183
Total Pages : 341 pages
Book Rating : 4.6/5 (16 download)
Download or read book The Animal Experimentation Debate written by David E. Newton and published by Bloomsbury Publishing USA. This book was released on 2013-05-09 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviewing the topic from antiquity to the present day, this book examines the debate over the use of animals in research in a fair and balanced way. The debate over the use of nonhuman animals in experimental research has gone on for centuries, and it continues as vigorously today as it ever has. In fact, in the last decade, the controversy has intensified, making animal testing a topic at the highest level of debate of any socioscientific issue in the United States. This book presents all sides of the issue so that readers can come to their own conclusions as to the morality and validity of animal experimentation, and provides biographies of individuals and descriptions of organizations that have been involved in the debate over the centuries. Additionally, it documents the historical shift in thinking that made animal experimentation commonplace between the time of the ancient Greeks and the 19th century, to the mindset of some who argue for an end to the practice and alternative ways of conducting medical experimentation to benefit human health.
Author : Heather A.E. Benson
Publisher : CRC Press
ISBN 13 : 1482235404
Total Pages : 479 pages
Book Rating : 4.4/5 (822 download)
Download or read book Cosmetic Formulation written by Heather A.E. Benson and published by CRC Press. This book was released on 2019-04-05 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the skin. It includes basic formulation, skin science, advanced formulation, and cosmetic product development, including both descriptive and mechanistic content with an emphasis on practical aspects. Key Features: Covers cosmetic products/formulation from theory to practice Includes case studies to illustrate real-life formulation development and problem solving Offers a practical, user-friendly approach, relying on the work of recognized experts in the field Provides insights into the future directions in cosmetic product development Presents basic formulation, skin science, advanced formulation and cosmetic product development
Author : Patrick Sharp
Publisher : CRC Press
ISBN 13 : 1439829861
Total Pages : 403 pages
Book Rating : 4.4/5 (398 download)
Download or read book The Laboratory Rat, Second Edition written by Patrick Sharp and published by CRC Press. This book was released on 2012-12-11 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.
Author :
Publisher :
ISBN 13 :
Total Pages : 70 pages
Book Rating : 4.3/5 (91 download)
Download or read book Animal Welfare Information Center Newsletter written by and published by . This book was released on 1996 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 452 pages
Book Rating : 4.:/5 ( download)
Download or read book Alternatives to Laboratory Animals written by and published by . This book was released on 2009 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Erika Jensen-Jarolim
Publisher : Springer Science & Business Media
ISBN 13 : 3709115590
Total Pages : 300 pages
Book Rating : 4.7/5 (91 download)
Download or read book Comparative Medicine written by Erika Jensen-Jarolim and published by Springer Science & Business Media. This book was released on 2013-12-09 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume provides a concise overview of the most basic and exciting chapters of comparative medicine with regards to physiology and function in healthy individuals. The book includes core concepts in anatomy and physiology in human and animal models, which are key to understanding comparative medicine and to making contributions to research in this area. While writing this book, the authors were in constant interdisciplinary dialogue. They aim to contribute to improvements in quality of life for human and animal patients.
Author : Jan Lauwereyns
Publisher : Springer
ISBN 13 : 3319893009
Total Pages : 134 pages
Book Rating : 4.3/5 (198 download)
Download or read book Rethinking the Three R's in Animal Research written by Jan Lauwereyns and published by Springer. This book was released on 2018-04-10 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work challenges the current reliance on "The Three R's" or Replacement, Reduction and Refinement which direct most animal research in the behavioral sciences. The author argues that these principles that were developed in the 1950's to guide the use of animals in research studies are outdated. He suggests that the notions of refinement and reduction are often ill-defined and can be useful only in cases where replacement is impossible.
