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The Synthesis Of Carbocyclic Compounds
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Book Synopsis Photochemical Synthesis by : I. Ninomiya
Download or read book Photochemical Synthesis written by I. Ninomiya and published by Academic Press. This book was released on 1989-01-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Synthetic Methods Series is aimed at practising organic chemists who require up-to-date details of working methods for the synthesis of organic compounds. This volume concentrates on the synthesis of compounds with specifictypes of structures which has not been possible by standard thermal methods. For ease of use the photochemical reactions covered have been presented by their functional groups.
Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 7 by : Daniel Lednicer
Download or read book The Organic Chemistry of Drug Synthesis, Volume 7 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
Book Synopsis Spiro Compounds by : Ramon Rios Torres
Download or read book Spiro Compounds written by Ramon Rios Torres and published by John Wiley & Sons. This book was released on 2022-03-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: SPIRO COMPOUNDS A comprehensive treatment of the latest research in, and applications of, spiro compounds Spiro Compounds: Synthesis and Applications combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, Spiro Compounds delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies. With a special focus on the mechanisms of the reactions that lead to the synthesis of spiro compounds, chapters in the book cover topics such as: The history, significance, and unique properties of spiro compounds The most important methodologies for their synthesis The applications of spiro compounds in organic chemistry, biology, drug discovery The most important syntheses of natural products bearing a spiro ring Perfect for academic and industrial chemists, this comprehensive discussion of spirocycles is an indispensable resource for those practicing in the field.
Book Synopsis Organic Synthesis Today and Tomorrow by : Barry M. Trost
Download or read book Organic Synthesis Today and Tomorrow written by Barry M. Trost and published by Elsevier. This book was released on 2017-01-31 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis: Today and Tomorrow covers the proceedings of the Third International Union of Pure and Applied Chemistry (IUPAC) Symposium on Organic Synthesis. The book covers topics that tackle relevant issues about organic chemistry. Comprised of 27 chapters, the book covers lectures that tackle topics pertaining organic chemistry. These topics include useful synthetic methods for general application; development of chemistry concepts for use in construction of molecular sub-assemblies; and interplay of synthetic methodology and the total synthesis of organic compounds. The book will be of great interest to scientists, such as biochemists who are concerned with the advances in organic chemistry.
Book Synopsis New Pathways for Organic Synthesis by : H.M. Colquhoun
Download or read book New Pathways for Organic Synthesis written by H.M. Colquhoun and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continually growing contribution of transition metal chemistry to synthetic organic chemistry is, of course, widely recognized. Equally well known is the difficulty in keeping up-to-date with the multifarious reactions and procedures that seem to be spawned at an ever-increasing rate. These can certainly be summarized on the basis of reviews under the headings of the individual transition metals. More useful to the bench organic chemist, however, would be the opposite type of concordance based on the structural type of the desired synthetic product. This is the approach taken in the present monograph, which presents for each structural entity a conspectus of the transition metal-mediated processes that can be employed in its production. The resulting comparative survey should be a great help in devising the optimum synthetic approach for a particular goal. It is presented from an essentially practical viewpoint, with detailed direc tions interspersed in the Houben-Weyl style. The wide scope of the volume should certainly encourage synthetic organic chemists to utilize fully the range and versatility of these transition metal-mediated processes. This will certainly be a well-thumbed reference book! R. A. RAPHAEL Cambridge University v Preface In recent years an enormous amount of work has been done on the catalysis of organic reactions by various transition metal species and on the organic reactivity of organo-transition-metal compounds.
Book Synopsis Handbook of Heterocyclic Chemistry by : Alan R. Katritzky
Download or read book Handbook of Heterocyclic Chemistry written by Alan R. Katritzky and published by Elsevier. This book was released on 2017-01-31 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.
Book Synopsis Strategies for Organic Drug Synthesis and Design by : Daniel Lednicer
Download or read book Strategies for Organic Drug Synthesis and Design written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2009-03-04 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.
Book Synopsis Chemical Synthesis of Nucleoside Analogues by : Pedro Merino
Download or read book Chemical Synthesis of Nucleoside Analogues written by Pedro Merino and published by John Wiley & Sons. This book was released on 2013-02-12 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiles current tested and proven approaches to synthesize novel nucleoside analogues Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of nucleoside analogues. Readers will learn to create new nucleoside analogues with desired therapeutic properties by using a variety of methods to chemically modify natural nucleosides, including: Changes to the heterocyclic base Modification of substituents at the sugar ring Replacement of the furanose ring by a different carbo- or heterocyclic ring Introduction of conformational restrictions Synthesis of enantiomers Preparation of hydrolitically stable C-nucleosides Chemical Synthesis of Nucleoside Analogues covers all the major classes of nucleosides, including pronucleotides, C-nucleosides, carbanucleosides, and PNA monomers which have shown great promise as starting points for the synthesis of nucleoside analogues. The book also includes experimental procedures for key reactions related to the synthesis of nucleoside analogues, providing a valuable tool for the preparation of a number of different compounds. Throughout the book, chemical schemes and figures help readers better understand the chemical structures of nucleoside analogues and the methods used to synthesize them. Extensive references serve as a gateway to the growing body of original research studies and reviews in the field. Synthetically modified nucleosides have proven their value as therapeutic drugs, in particular as antiviral and antitumor agents. However, many of these nucleoside analogues have undesirable side effects. With Chemical Synthesis of Nucleoside Analogues as their guide, researchers have a new tool for synthesizing a new generation of nucleoside analogues that can be used as therapeutic drugs with fewer unwanted side effects.
Book Synopsis Modern Applications of Cycloaddition Chemistry by : Paolo Quadrelli
Download or read book Modern Applications of Cycloaddition Chemistry written by Paolo Quadrelli and published by Elsevier. This book was released on 2019-03-20 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. - Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes - Contains the most up-to-date review of the use of pericyclic reactions in drug delivery - Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected - Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area
Download or read book Azoles written by Aleksey Kuznetsov and published by BoD – Books on Demand. This book was released on 2021-06-30 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Azoles are a broad and promising class of five-membered heterocyclic compounds containing from one up to five nitrogen atom(s) that can also contain sulfur or oxygen atoms. Widely used as potent antifungal agents, various azole derivatives have also demonstrated many other promising biological properties. This book covers studies of several types of thiazole-based heterocyclic scaffolds, the development of 4-thiazolidinone and thiazole derivatives with heterocyclic fragments as potential candidates for new drugs against trypanosomiasis, numerous synthetic approaches for the synthesis of 1,2,3-triazoles, the application of N-azole, N,S-azole, and N,O-azole as well as their derivatives as retarders of metallic corrosion, and the integration of azoles in materials used for renewable energy processing and applications and wood treatment.
Book Synopsis Modern Rhodium-Catalyzed Organic Reactions by : P. Andrew Evans
Download or read book Modern Rhodium-Catalyzed Organic Reactions written by P. Andrew Evans and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhodium has proven to be an extremely useful metal due to its ability to catalyze an array of synthetic transformations, with quite often-unique selectivity. Hydrogenation, C-H activation, allylic substitution, and numerous other reactions are catalyzed by this metal, which presumably accounts for the dramatic increase in the number of articles that have recently emerged on the topic. P. Andrew Evans, the editor of this much-needed book, has assembled an internationally renowned team to present the first comprehensive coverage of this important area. The book features contributions from leaders in the field of rhodium-catalyzed reactions, and thereby provides a detailed account of the most current developments, including: Rhodium-Catalyzed Asymmetric Hydrogenation (Zhang) Rhodium-Catalyzed Hydroborations and Related Reactions (Brown) Rhodium-Catalyzed Asymmetric Addition of Organometallic Reagents to Electron Deficient Olefins (Hayashi) Recent Advances in Rhodium(I)-Catalyzed Asymmetric Olefin Isomerization and Hydroacylation Reactions (Fu) Stereoselective Rhodium(I)-Catalyzed Hydroformylation and Silylformylation Reactions and Their Application to Organic Synthesis (Leighton) Carbon-Carbon Bond-Forming Reactions Starting from Rh-H or Rh-Si Species (Matsuda) Rhodium(I)-Catalyzed Cycloisomerization and Cyclotrimerization Reactions (Ojima) The Rhodium(I)-Catalyzed Alder-ene Reaction (Brummond) Rhodium-Catalyzed Nucleophilic Ring Cleaving Reactions of Allylic Ethers and Amines (Fagnou) Rhodium(I)-Catalyzed Allylic Substitution Reactions and their Applications to Target Directed Synthesis (Evans) Rhodium(I)-Catalyzed [2+2+1] and [4+1] Carbocyclization Reactions (Jeong) Rhodium(I)-Catalyzed [4+2] and [4+2+2] Carbocyclizations (Robinson) Rhodium(I)-Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis (Wender) Rhodium(II)-Stabilized Carbenoids Containing both Donor and Acceptor Substituents (Davies) Chiral Dirhodium(II)Carboxamidates for Asymmetric Cyclopropanation and Carbon-Hydrogen Insertion Reactions (Doyle) Cyclopentane Construction by Rhodium(II)-Mediated Intramolecular C-H Insertion (Taber) Rhodium(II)-Catalyzed Oxidative Amination (DuBois) Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)-Catalyzed Carbene-Transfer (West) Rhodium(II)-Catalyzed 1,3-Dipolar Cycloaddition Reactions (Austin) "Modern Rhodium-Catalyzed Organic Reactions" is an essential reference text for researchers at all levels in the general area of organic chemistry. This book provides an invaluable overview of the most significant developments in this important area of research, and will no doubt be an essential text for researchers at academic institutions and professionals at pharmaceutical/agrochemical companies.
Book Synopsis Cycloaddition Reactions in Organic Synthesis by : Shu Kobayashi
Download or read book Cycloaddition Reactions in Organic Synthesis written by Shu Kobayashi and published by John Wiley & Sons. This book was released on 2002 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the miners' strike in the 1980s, a worker is killed in the striking coalfields of Wales. Some months later, a government minister thought to be connected with the death is also shot. Lewis Redfern—once a radical but now a political analyst and journalist—pursues the sniper, a lonely hunt that leads him through an imbroglio of civil service leaks to a secret organization: a source of insurrection far more powerful than anyone could have suspected known as the Volunteers. In this fast-paced narrative of espionage and intrigue, Redfern, through his obsessive pursuit of justice, finally encounters the truth about himself as the novel discusses the conflict between moral choice and political loyalty.
Book Synopsis Carboxylic Acid by : Georgiana-Ileana Badea
Download or read book Carboxylic Acid written by Georgiana-Ileana Badea and published by BoD – Books on Demand. This book was released on 2018-06-13 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an attempt to bring together current knowledge on the role and importance of organic acids in life processes. There are lots of compounds based on the chemical nature of this functional group, which makes this class of molecules to be present in our lives starting with the human body (Krebs cycle - the core of cellular metabolism) to the products we currently use (food, medicines and cosmetics). No overall consensus is sought in this book, and the following chapters are authored by dedicated researchers presenting a diversity of applications and hypotheses concerning organic acids. The five chapters in this book include general information on carboxylic acids and their applications in life sciences (use in organic synthesis, nanotechnology, plant physiology, plant nutrition and soil chemistry).
Book Synopsis Cycloaddition Reactions in Organic Synthesis by : W. Carruthers
Download or read book Cycloaddition Reactions in Organic Synthesis written by W. Carruthers and published by Elsevier. This book was released on 2013-10-22 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates the wide scope of cycloaddition reactions, including the Diels-Alder reaction, the ene reaction, 1,3-dipolar cycloadditions and [2+2] cycloadditions in organic synthesis. The author, a leading exponent of the subject, illustrates the ways in which they can be employed in the synthesis of a wide range of carbocyclic and heterocyclic compounds, including a variety of natural products of various types. Special attention is given to intramolecular reactions, which often provide a rapid and efficient route to polycyclic compounds, and to the stereochemistry of the reactions, including recent and developing work on enantioselective synthesis.
Book Synopsis Organic Chemistry: Chemistry of the carbocyclic compounds; tr. from the 11th German ed. by E. E. Fournier d'Albe, 1922 by : Victor von Richter
Download or read book Organic Chemistry: Chemistry of the carbocyclic compounds; tr. from the 11th German ed. by E. E. Fournier d'Albe, 1922 written by Victor von Richter and published by . This book was released on 1922 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Catalytic Hydrogenation in Organic Syntheses by : Rylander
Download or read book Catalytic Hydrogenation in Organic Syntheses written by Rylander and published by Elsevier. This book was released on 2012-12-02 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catalytic Hydrogenation in Organic Syntheses focuses on the process of catalytic hydrogenation in organic synthesis. This book gives the reader easy access to catalytic history, to show what can be done and how to do it. A variety of working generalities and common sense guides are given as aids in selecting catalytic metal, catalyst support, concentration of metal and catalyst, solvent, and reaction conditions. All manner of hydrogenation catalysts are considered and mechanisms of hydrogenation are presented at a level that is useful to the synthetic organic chemist. This volume is comprised of 15 chapters and begins with an overview of catalytic hydrogenation and heterogeneous hydrogenation catalysts, along with hydrogenation reactors and reaction conditions. The discussion then shifts to the hydrogenation of compounds such as acetylenes, olefins, aldehydes, ketones, nitriles, oximes, acids, esters, lactones, anhydrides, and nitro compounds as well as carbocyclic aromatics and heterocyclic compounds. The reader is also introduced to reductive alkylation, catalytic dehydrohalogenation, and hydrogenolysis of small rings. A chapter on miscellaneous hydrogenolyses concludes the book. This book will be of interest to organic chemists working in the field of catalytic hydrogenation.
Book Synopsis Reactions of Organosulfur Compounds by : Eric Block
Download or read book Reactions of Organosulfur Compounds written by Eric Block and published by Academic Press. This book was released on 2013-10-22 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 37: Reactions of Organosulfur Compounds covers the basics of organosulfur chemistry and the characteristics of organically bound sulfur, with an emphasis on reactions, particularly those of synthetic utility. The book discusses the preparation, nature, stereochemical aspects, reactions, and the kinetic and thermodynamic assessment of the stability of sulfur-containing carbanions; the preparation and reactions of sulfur ylides; and the preparation, assessment of stability, and reactions of sulfur-containing carbocations. The text also describes preparation, assessment of stability, nature, and reactions of sulfur-containing radicals, organosulfur carbenes, and carbenoids; as well as the the pericyclic reactions of organosulfur compounds. Chemists, biochemists, and students taking related courses will find the book useful.
