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Author : Emma Modrate
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (23 download)
Download or read book The Synthesis and Characterisation of Supported Dendrimer Systems written by Emma Modrate and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kevin Andrew Knights
Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.:/5 (729 download)
Download or read book Design, Synthesis and Characterisation of a New Polymer-supported Dendrimer written by Kevin Andrew Knights and published by . This book was released on 2003 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael Malkoch
Publisher : Royal Society of Chemistry
ISBN 13 : 1788011325
Total Pages : 327 pages
Book Rating : 4.7/5 (88 download)
Download or read book Dendrimer Chemistry written by Michael Malkoch and published by Royal Society of Chemistry. This book was released on 2020 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the latest advances in the synthesis, characterization and applications of dendrimers and other complex dendritic architectures.
Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128212519
Total Pages : 486 pages
Book Rating : 4.1/5 (282 download)
Download or read book Dendrimer-Based Nanotherapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2021-04-14 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. - Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive - Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine - Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher
Author : Roseita Esfand
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (62 download)
Download or read book Synthesis and Characterisation of Dendrimer-drug Complexes and Evaluation of Dendrimeric Compounds as Novel Drug Delivery Systems written by Roseita Esfand and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fritz Vögtle
Publisher : John Wiley & Sons
ISBN 13 : 3527626964
Total Pages : 354 pages
Book Rating : 4.5/5 (276 download)
Download or read book Dendrimer Chemistry written by Fritz Vögtle and published by John Wiley & Sons. This book was released on 2009-03-09 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally acclaimed authors, this textbook contains everything you need to know about this versatile class of compounds. Starting with a historical overview, definitions and other fundamentals, it goes on to look at characterization, analysis and properties of dendrimers. While the focus is on synthesis and applications, it also contains chapters on analytics and other applications. Essential reading for organic and polymer chemists, undergraduate and graduate students, students and lecturers in chemistry.
Author : Sebastiano Campagna
Publisher : John Wiley & Sons
ISBN 13 : 1118111060
Total Pages : 726 pages
Book Rating : 4.1/5 (181 download)
Download or read book Designing Dendrimers written by Sebastiano Campagna and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on dendrimers has exploded in the last 15 years, moving from the establishment of synthetic methodologies, particularly in the early years up to the end of nineties, towards sophisticated and wide-ranging applications. Dendrimers play an important role in many different areas, spanning from basic synthetic approaches to artificial photosynthesis, to medicine, to catalysis. The great potential of dendrimers is well-recognized by the hundreds of papers in the field and the increasing number of patents, and stimulated developments in other areas of knowledge, including new characterization techniques. However, some basic principles and methods still continue to give a unity to the field. Although several books on dendrimers have been published during these 15 years, the very recent progresses in new areas now requires a new point of view, trying to give a unifying and comprehensive outlook of the field. Since the first dendrimer was synthesized by Vögtle in 1978, dendrimers have experienced an explosion of scientific interest because of their unique molecular architecture. This resulted in over 5,000 scientific papers and patents published by the end of 2005. The proposed book will cover both fundamental and applicative aspects of dendrimer research. Chapters devoted to basic principles, synthetic methods and strategies, and advanced characterization techniques will be integrated by chapters illustrating the full potential of dendrimers in various fields, like artificial photosynthesis, multi-redox pool systems, diagnostics, biomedical and sensing purposes, design of functional nanostructures. Particular emphasis will be devoted to possible future developments.
Author : Neelesh Kumar Mehra
Publisher : CRC Press
ISBN 13 : 1000333175
Total Pages : 401 pages
Book Rating : 4.0/5 (3 download)
Download or read book Dendrimers in Nanomedicine written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-03-24 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.
Author : Anne-Marie Caminade
Publisher : CRC Press
ISBN 13 : 1351617303
Total Pages : 372 pages
Book Rating : 4.3/5 (516 download)
Download or read book Phosphorous Dendrimers in Biology and Nanomedicine written by Anne-Marie Caminade and published by CRC Press. This book was released on 2018-05-03 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers, which are hyperbranched synthetic macromolecules, have attracted researchers’ increasing interest over the last three decades owing to their numerous properties, in particular, in the fields of biology and nanomedicine. This book is an up-to-date collection of the most recent achievements in the use of dendrimers in nanomedicine, exemplified by phosphorus-containing dendrimers. Starting with the synthesis and characterization of phosphorus dendrimers, the book discusses their use as biomaterials, carriers of biological entities, and anti-inflammatory drugs; in bioimaging; and against prion diseases, Alzheimer’s, HIV, and cancer. It compares phosphorus dendrimers with other types of dendrimers. Supplemented with numerous references and abundant illustrations, the book opens new perspectives for the researchers working on dendrimers.
Author : José Callejas-Fernández
Publisher : Royal Society of Chemistry
ISBN 13 : 1782625216
Total Pages : 411 pages
Book Rating : 4.7/5 (826 download)
Download or read book Soft Nanoparticles for Biomedical Applications written by José Callejas-Fernández and published by Royal Society of Chemistry. This book was released on 2014-06-18 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles are attractive for many biomedical applications such as imaging, therapeutics and diagnostics. This new book looks at different soft nanoparticles and their current and potential uses in medicine and health including magnetoliposomes, micro/nanogels, polymeric micelles, DNA particles, dendrimers and bicelles. Each chapter provides a description of the synthesis of the particles and focus on the techniques used to characterize the size, shape, surface charge, internal structure, and surface microstructure of the nanoparticles together with modeling and simulation methods. By giving a strong physical-chemical approach to the topic, readers will gain a good background into the subject and an overview of recent developments. The multidisciplinary point of view makes the book suitable for postgraduate students and researchers in physics, chemistry, and biology interested in soft matter and its uses.
Author : Yiyun Cheng
Publisher : John Wiley & Sons
ISBN 13 : 0470460059
Total Pages : 542 pages
Book Rating : 4.4/5 (74 download)
Download or read book Dendrimer-Based Drug Delivery Systems written by Yiyun Cheng and published by John Wiley & Sons. This book was released on 2012-07-03 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.
![Download Synthesis and Characterisation of a Novel Class of Chiral Poly( Aromatic Aminde) Dendrimers Incorporating a C3-symmetric Core System Derived from the [alpha]-amino Acids L- and D-serine PDF Online Free](https://books.google.com/books/content/images/frontcover/qblTMwEACAAJ?fife=w200-h370)
Author : Barbara Romagnoli
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (824 download)
Download or read book Synthesis and Characterisation of a Novel Class of Chiral Poly( Aromatic Aminde) Dendrimers Incorporating a C3-symmetric Core System Derived from the [alpha]-amino Acids L- and D-serine written by Barbara Romagnoli and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Barbara Klajnert
Publisher : Royal Society of Chemistry
ISBN 13 : 1849736111
Total Pages : 215 pages
Book Rating : 4.8/5 (497 download)
Download or read book Dendrimers in Biomedical Applications written by Barbara Klajnert and published by Royal Society of Chemistry. This book was released on 2013 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide comprehensive coverage of dendrimer applications and clear indications for future research. It will appeal to chemists, biologists and materials scientists, working in both academia and industry.
Author : Malcolm L. Cooper
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (643 download)
Download or read book The Synthesis and Characterisation of Novel Dendrimer Centres written by Malcolm L. Cooper and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hannah Louise Crampton
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (69 download)
Download or read book Synthesis and Characterization of Melamine-based Dendrimers with Potential Biological Applications written by Hannah Louise Crampton and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The convergent strategy towards dendrimer synthesis is well-suited to generate macromolecules with a diverse periphery, at the expense of time and effort, while the divergent strategy has historically been effective at yielding higher generation dendrimers, although they are often plagued by impurities. Both the convergent and divergent routes were applied to the synthesis of melamine-based dendrimers, offering a comparison of the routes within a system. Generation-1 dendrons heterogeneously functionalized with Boc-protected amines and hydrazones were synthesized convergently and coupled to a generation-1 tris(piperazine) core to yield a generation-2 dendrimer bearing 18 Boc-amines and three hydrazones. Although the yield for the final coupling step was rather low (56%), the yields for all intermediate steps were quite high. Attempts toward obtaining a generation-3 dendrimer through this route were unsuccessful due presumably to steric hindrance. The materials obtained showed no impurities in their 1H and 13C NMR and mass spectra, although several chromatographic purifications were necessary throughout the synthesis. A divergent strategy based on addition of a dichlorotriazine monomer to polyamine cores was used to synthesize dendrimers of generations 1-5. All intermediates and dendrimers were either purified by precipitation, or did not need purification. 1H NMR spectroscopy indicated that reactions were complete up to G4-NH2 by integration, and mass spectroscopy confirmed that assignment. HPLC and GPC of Gn-Cl dendrimers showed sharp peaks for G1-G3, but G4-Cl appeared to have a small amount of impurities that are similar in size and polarity to the fully-substituted dendrimer. The G1-G3 dendrimers were confidently assigned as pure by conventional organic chemistry standards, but the assignment of purity to higher generations remained tentative. A G1-Cl dendrimer was functionalized with imidazole, and then deprotected and PEGylated with PEG5000 to yield a water soluble dendrimer. The imidazole-capped, Boc-protected dendrimer and the deprotected dendrimer were characterized by 1H and 13C NMR spectroscopy and mass spectrometry. The degree of PEGylation on the PEGylated material could not be definitively ascertained; however, the material is capable of solubilizing very hydrophobic Zn-phthalocyanines in water.
Author : Luke C. De Selm
Publisher :
ISBN 13 :
Total Pages : 198 pages
Book Rating : 4.:/5 (66 download)
Download or read book Synthesis and Characterization of Novel Carbosilane Dendrimers as Supports written by Luke C. De Selm and published by . This book was released on 2004 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel L. Fedlheim
Publisher : CRC Press
ISBN 13 : 9780585404394
Total Pages : 348 pages
Book Rating : 4.4/5 (43 download)
Download or read book Metal Nanoparticles written by Daniel L. Fedlheim and published by CRC Press. This book was released on 2001-10-26 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art reference, Metal Nanoparticles offers the latest research on the synthesis, characterization, and applications of nanoparticles. Following an introduction of structural, optical, electronic, and electrochemical properties of nanoparticles, the book elaborates on nanoclusters, hyper-Raleigh scattering, nanoarrays, and several applications including single electron devices, chemical sensors, biomolecule sensors, and DNA detection. The text emphasizes how size, shape, and surface chemistry affect particle performance throughout. Topics include synthesis and formation of nanoclusters, nanosphere lithography, modeling of nanoparticle optical properties, and biomolecule sensors.
