The Second Generation Of The Cccm System For In Vitro Cardiac Tissue Engineering

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The Second Generation of the CCCM System for In-vitro Cardiac Tissue Engineering

Author : Mai-Dung Thi Nguyen
Publisher :
ISBN 13 :
Total Pages : 153 pages
Book Rating : 4.:/5 (926 download)

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Book Synopsis The Second Generation of the CCCM System for In-vitro Cardiac Tissue Engineering by : Mai-Dung Thi Nguyen

Download or read book The Second Generation of the CCCM System for In-vitro Cardiac Tissue Engineering written by Mai-Dung Thi Nguyen and published by . This book was released on 2014 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the leading cause of death worldwide. When a myocardial infarction occurs, scar tissue compensates the damaged myocardial tissue. This scar tissue increases the stiffness of the heart tissue, reduces the heart's function, and finally leads to the heart failure (HF) disease. To have the tissue engraftment, in-vitro cardiac tissue should have the same properties as the native mature cardiac tissue. However, current in-vitro cell culture technologies fail to accurately recreate the in-vivo like mechanically physiological environment for in-vitro cardiac tissue culture, and therefore, fail to regenerate the in-vivo like mature cardiac tissue. Hence, a microfluidic cardiac cell culture model (CCCM) system was developed to better recreate the cellular environment and advance cardiac regeneration. CCCM system replicates the hemodynamic loading and unloading conditions occurring inside the left ventricle of a heart. With this system, different pressures of human heart conditions may be replicated for a variety of clinical and physiologic conditions. For proof-of-concept, embryonic chick cardiac cells with normal heart condition were applied. Compared to the tissue cultured in a static condition, tissues stimulated in the CCCM system achieved an in-vivo like cardiac matured phenotype, had higher proliferating rate, showed more maturity, and expressed more contractile proteins. These results demonstrated that the CCCM system can be used to study the behavior of cardiomyocytes in different mechanical heart conditions and to create mature cardiac tissue which will benefit cardiac tissue transplant for HF.

The Hepatocyte Review

Author : M. N. Berry
Publisher : Springer Science & Business Media
ISBN 13 : 9780792361770
Total Pages : 630 pages
Book Rating : 4.3/5 (617 download)

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Book Synopsis The Hepatocyte Review by : M. N. Berry

Download or read book The Hepatocyte Review written by M. N. Berry and published by Springer Science & Business Media. This book was released on 2000-12-31 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is thirty years since the technique of high-yield preparation of isolated hepatocytes, by collagenase perfusion of the liver, was published. The original method described by Berry and Friend has undergone many minor modifications by other workers, and the two-step procedure introduced by Seglen in 1976 has become the most frequent way to prepare hepatocyte suspensions. An important development introduced by Bissell in 1973 was the use of the cells as the first step in monolayer culture. The availability of the isolated hepatocyte preparation as cells in suspension or culture has undoubtedly facilitated research on the liver. This was emphasised in our book, published (with Dr. Greg Barritt) in 1990, which described in detail methods of preparation and the properties of the isolated hepatocytes. It also discussed the usefulness of the preparation for the study of intermediary and xenobiotic metabolism, calcium ion transport, and the growth and differentiation of hepatocytes in culture. The book also touched briefly on a range of specialised techniques, including peri fusion, subcellular fractionation, transplantation, cryopreservation and measurement of intracellular pH. Although standard procedures for the manipulation of hepatocytes have not changed a great deal in ten years, they have undoubtedly been refined. This applies particularly to hepatocyte culture techniques, cryopreservation, and even to preparation of hepatocyte suspensions, where it is now feasible to use purified enzymes. There is also much more emphasis on the use and study of human hepatocytes, particularly in the field of pharmacology and therapeutics.

Technical Report Series

Author :
Publisher :
ISBN 13 : 9789241209021
Total Pages : 208 pages
Book Rating : 4.2/5 (9 download)

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Book Synopsis Technical Report Series by :

Download or read book Technical Report Series written by and published by . This book was released on 1950 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Global Tea Breeding

Author : Liang Chen
Publisher : Springer Science & Business Media
ISBN 13 : 3642318789
Total Pages : 400 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Global Tea Breeding by : Liang Chen

Download or read book Global Tea Breeding written by Liang Chen and published by Springer Science & Business Media. This book was released on 2013-08-31 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Tea Breeding: Achievements, Challenges and Perspectives provides a global review on biodiversity and biotechnology issues in tea breeding and selection. The contributions are written by experts from China, India, Kenya, Sri Lanka, Vietnam, Turkey, Indonesia, Japan, Bangladesh, Korea, Nigeria, and etc., which countries amount to 90% of the world tea production. This book focuses on the germplasm, breeding and selection of tea cultivars for the production of black, green and Oolong teas from the tea plant, Camellia sinensis (L.) O. Kuntze. It can benefit the tea breeders in the global tea industry, as well as the breeders of other woody cash crops like coffee and other sub-tropical fruit trees. Liang Chen is a Professor and Associate Director at National Center for Tea Improvement, Tea Research Institute of the Chinese Academy of Agricultural Sciences (TRICAAS), Hangzhou, China. Zeno Apostolides is a Professor at the Department of Biochemistry, University of Pretoria, South Africa. Zong-Mao Chen is the Academician of the Chinese Academy of Engineering and a Professor at the Tea Research Institute of the Chinese Academy of Agricultural Sciences, Hangzhou, China.

Natural Resources in Wetlands

Author : Marcos Antônio Soares
Publisher :
ISBN 13 : 9788561377939
Total Pages : 287 pages
Book Rating : 4.3/5 (779 download)

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Book Synopsis Natural Resources in Wetlands by : Marcos Antônio Soares

Download or read book Natural Resources in Wetlands written by Marcos Antônio Soares and published by . This book was released on 2017 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Natural Resources Book in Wetlands From Pantanal to Amazonia edited by the Museu Paraense Emilio Goeldi / National Pantanal Research Institute is to promote the publication, dissemination and socialization in the national and international scope of the intellectual production on Biodiversity, Biotechnology and Innovation that deals exclusively with the Pantanal Biome and Amazon Biome through information on the biological diversity of populations and communities of animals, plants and microorganisms and their ecological patterns and processes, Development of technologies, patents and innovations, as well as biotechnological products and processes based on biodiversity. It contemplated researches carried out by teachers and Students of the Doctoral Program in Biodiversity and Biotechnology in Network Regional North Pará; Doctors and Students of the Doctoral Program in Network Regional Center West (MT, MS, GO and DF) and Researchers of the National Institute of Science and Technology in Wetlands (INAU)."--Page 5.

Handbook of Fibrous Materials, 2 Volumes

Author : Jinlian Hu
Publisher : John Wiley & Sons
ISBN 13 : 3527342206
Total Pages : 1040 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Handbook of Fibrous Materials, 2 Volumes by : Jinlian Hu

Download or read book Handbook of Fibrous Materials, 2 Volumes written by Jinlian Hu and published by John Wiley & Sons. This book was released on 2020-06-22 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by a leading expert in the field with contributions from experienced researchers in fibers and textiles, this handbook reviews the current state of fibrous materials and provides a broad overview of their use in research and development. Volume One focuses on the classes of fibers, their production and characterization, while the second volume concentrates on their applications, including emerging ones in the areas of energy, environmental science and healthcare. Unparalleled knowledge of high relevance to academia and industry.

Physical Chemistry of Macromolecules

Author : S. F. Sun
Publisher : John Wiley & Sons
ISBN 13 : 0471281387
Total Pages : 590 pages
Book Rating : 4.4/5 (712 download)

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Book Synopsis Physical Chemistry of Macromolecules by : S. F. Sun

Download or read book Physical Chemistry of Macromolecules written by S. F. Sun and published by John Wiley & Sons. This book was released on 2004-01-28 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating coverage of polymers and biological macromolecules into a single text, Physical Chemistry of Macromolecules is carefully structured to provide a clear and consistent resource for beginners and professionals alike. The basic knowledge of both biophysical and physical polymer chemistry is covered, along with important terms, basic structural properties and relationships. This book includes end of chapter problems and references, and also: Enables users to improve basic knowledge of biophysical chemistry and physical polymer chemistry. Explores fully the principles of macromolecular chemistry, methods for determining molecular weight and configuration of molecules, the structure of macromolecules, and their separations.

Molecular Infection Biology

Author : Jörg Hinrich Hacker
Publisher : Wiley-Spektrum
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Infection Biology by : Jörg Hinrich Hacker

Download or read book Molecular Infection Biology written by Jörg Hinrich Hacker and published by Wiley-Spektrum. This book was released on 2002-10-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.

Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis

Author : Padma V. Devarajan
Publisher : Springer Nature
ISBN 13 : 3030291685
Total Pages : 560 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis by : Padma V. Devarajan

Download or read book Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis written by Padma V. Devarajan and published by Springer Nature. This book was released on 2019-11-09 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.

Bioinspired Engineering of Thermal Materials

Author : Tao Deng
Publisher : John Wiley & Sons
ISBN 13 : 3527338349
Total Pages : 274 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Bioinspired Engineering of Thermal Materials by : Tao Deng

Download or read book Bioinspired Engineering of Thermal Materials written by Tao Deng and published by John Wiley & Sons. This book was released on 2018-06-11 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview and summary of recent achievements and the latest trends in bioinspired thermal materials. Following an introduction to different thermal materials and their effective heat transfer to other materials, the text discusses heat detection materials that are inspired by biological systems, such as fire beetles and butterflies. There then follow descriptions of materials with thermal management functionality, including those for evaporation and condensation, heat transfer and thermal insulation materials, as modeled on snake skins, polar bears and fire-resistant trees. A discussion of thermoresponsive materials with thermally switchable surfaces and controllable nanochannels as well as those with high thermal conductivity and piezoelectric sensors is rounded off by a look toward future trends in the bioinspired engineering of thermal materials. Straightforward and well structured, this is an essential reference for newcomers as well as experienced researchers in this exciting field.

Medical Infrared Imaging

Author : Mary Diakides
Publisher : CRC Press
ISBN 13 : 143987249X
Total Pages : 641 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Medical Infrared Imaging by : Mary Diakides

Download or read book Medical Infrared Imaging written by Mary Diakides and published by CRC Press. This book was released on 2012-12-12 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolution of technological advances in infrared sensor technology, image processing, "smart" algorithms, knowledge-based databases, and their overall system integration has resulted in new methods of research and use in medical infrared imaging. The development of infrared cameras with focal plane arrays no longer requiring cooling, added a new dimension to this modality. Medical Infrared Imaging: Principles and Practices covers new ideas, concepts, and technologies along with historical background and clinical applications. The book begins by exploring worldwide advances in the medical applications of thermal imaging systems. It covers technology and hardware including detectors, detector materials, un-cooled focal plane arrays, high performance systems, camera characterization, electronics for on-chip image processing, optics, and cost-reduction designs. It then discusses the physiological basis of the thermal signature and its interpretation in a medical setting. The book also covers novel and emerging techniques, the complexities and importance of protocols for effective and reproducible results, storage and retrieval of thermal images, and ethical obligations. Of interest to both the medical and biomedical engineering communities, the book explores many opportunities for developing and conducting multidisciplinary research in many areas of medical infrared imaging. These range from clinical quantification to intelligent image processing for enhancement of the interpretation of images, and for further development of user-friendly high-resolution thermal cameras. These would enable the wide use of infrared imaging as a viable, noninvasive, low-cost, first-line detection modality.

DNA-containing Membrane Vesicles of Pseudomonas Aeruginosa PAO1 and Their Genetic Transformation Potential [microform]

Author : Marika Renelli
Publisher : National Library of Canada = Bibliothèque nationale du Canada
ISBN 13 : 9780612906921
Total Pages : 106 pages
Book Rating : 4.9/5 (69 download)

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Book Synopsis DNA-containing Membrane Vesicles of Pseudomonas Aeruginosa PAO1 and Their Genetic Transformation Potential [microform] by : Marika Renelli

Download or read book DNA-containing Membrane Vesicles of Pseudomonas Aeruginosa PAO1 and Their Genetic Transformation Potential [microform] written by Marika Renelli and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 2004 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nano Devices and Circuit Techniques for Low-Energy Applications and Energy Harvesting

Author : Chong-Min Kyung
Publisher : Springer
ISBN 13 : 9401799903
Total Pages : 292 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Nano Devices and Circuit Techniques for Low-Energy Applications and Energy Harvesting by : Chong-Min Kyung

Download or read book Nano Devices and Circuit Techniques for Low-Energy Applications and Energy Harvesting written by Chong-Min Kyung and published by Springer. This book was released on 2015-07-16 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the development of core technologies to address two of the most challenging issues in research for future IT platform development, namely innovative device design and reduction of energy consumption. Three key devices, the FinFET, the TunnelFET, and the electromechanical nanoswitch are described with extensive details of use for practical applications. Energy issues are also covered in a tutorial fashion from material physics, through device technology, to innovative circuit design. The strength of this book lies in its holistic approach dealing with material trends, state-of-the-art of key devices, new examples of circuits and systems applications. This is the first of three books based on the Integrated Smart Sensors research project, which describe the development of innovative devices, circuits, and system-level enabling technologies. The aim of the project was to develop common platforms on which various devices and sensors can be loaded, and to create systems offering significant improvements in information processing speed, energy usage, and size. The book contains extensive reference lists and with over 200 figures introduces the reader to the general subject in a tutorial style, also addressing the state-of-the-art, allowing it to be used as a guide for starting researchers in these fields.

Metal-Organic Frameworks for Biomedical Applications

Author : Masoud Mozafari
Publisher : Woodhead Publishing
ISBN 13 : 0128169842
Total Pages : 584 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Metal-Organic Frameworks for Biomedical Applications by : Masoud Mozafari

Download or read book Metal-Organic Frameworks for Biomedical Applications written by Masoud Mozafari and published by Woodhead Publishing. This book was released on 2020-03-17 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-Organic Frameworks for Biomedical Applications is a comprehensive, authoritative reference that offers a substantial and complete treatment of published results that have yet to be critically reviewed. It offers a summary of current research and provides in-depth understanding of the role of metal-organic frameworks in biomedical engineering. The title consists of twenty-two chapters presented by leading international researchers in the field. Chapters are arranged by target-application in biomedical engineering, allowing medical and pharmaceutic specialists to translate current materials and engineering science on metal-organic frameworks into their work. Presents the state-of-the art in metal-organic frameworks for biomedical applications Offers comprehensive treatment of metal-organic frameworks that is useful to pharmaceutic and medical experts who are non-specialists in materials science Helps materials scientists and engineers understand the needs of biomedical engineering Critically-reviews published results and current research in the field

Magnetic Nanoparticle-Based Hybrid Materials

Author : Andrea Ehrmann
Publisher : Woodhead Publishing
ISBN 13 : 0128236892
Total Pages : 761 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Magnetic Nanoparticle-Based Hybrid Materials by : Andrea Ehrmann

Download or read book Magnetic Nanoparticle-Based Hybrid Materials written by Andrea Ehrmann and published by Woodhead Publishing. This book was released on 2021-06-23 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Nanoparticle-Based Hybrid Materials: Fundamentals and Applications introduces the principles, properties, and emerging applications of this important materials system. The hybridization of magnetic nanoparticles with metals, metal oxides and semiconducting nanoparticles may result in superior properties. The book reviews the most relevant hybrid materials, their mechanisms and properties. Then, the book focuses on the rational design, controlled synthesis, advanced characterizations and in-depth understanding of structure-property relationships. The last part addresses the promising applications of hybrid nanomaterials in the real world such as in the environment, energy, medicine fields. Magnetic Nanoparticle-Based Hybrid Materials: Fundamentals and Applications comprehensively reviews both the theoretical and experimental approaches used to rapidly advance nanomaterials that could result in new technologies that impact day-to-day life and society in key areas such as health and the environment. It is suitable for researchers and practitioners who are materials scientists and engineers, chemists or physicists in academia and R&D. Provides in-depth information on the basic principles of magnetic nanoparticles-based hybrid materials such as synthesis, characterization, properties, and magnon interactions Discusses the most relevant hybrid materials systems including integration of metals, metal oxides, polymers, carbon and more Addresses the emerging applications in medicine, the environment, energy, sensing, and computing enabled by magnetic nanoparticles-based hybrid materials

Progress against cancer

Author : Education U.S. Department of Health (and Welfare)
Publisher :
ISBN 13 :
Total Pages : 44 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Progress against cancer by : Education U.S. Department of Health (and Welfare)

Download or read book Progress against cancer written by Education U.S. Department of Health (and Welfare) and published by . This book was released on 1962 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bayesian Data Analysis, Third Edition

Author : Andrew Gelman
Publisher : CRC Press
ISBN 13 : 1439840954
Total Pages : 677 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Data Analysis, Third Edition by : Andrew Gelman

Download or read book Bayesian Data Analysis, Third Edition written by Andrew Gelman and published by CRC Press. This book was released on 2013-11-01 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied approach to analysis using up-to-date Bayesian methods. The authors—all leaders in the statistics community—introduce basic concepts from a data-analytic perspective before presenting advanced methods. Throughout the text, numerous worked examples drawn from real applications and research emphasize the use of Bayesian inference in practice. New to the Third Edition Four new chapters on nonparametric modeling Coverage of weakly informative priors and boundary-avoiding priors Updated discussion of cross-validation and predictive information criteria Improved convergence monitoring and effective sample size calculations for iterative simulation Presentations of Hamiltonian Monte Carlo, variational Bayes, and expectation propagation New and revised software code The book can be used in three different ways. For undergraduate students, it introduces Bayesian inference starting from first principles. For graduate students, the text presents effective current approaches to Bayesian modeling and computation in statistics and related fields. For researchers, it provides an assortment of Bayesian methods in applied statistics. Additional materials, including data sets used in the examples, solutions to selected exercises, and software instructions, are available on the book’s web page.