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Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)
Download or read book Toxicological Profile for N-nitrosodimethylamine written by and published by . This book was released on 1989 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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ISBN 13 :
Total Pages : 1470 pages
Book Rating : 4.:/5 (31 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lewis B. Holmes
Publisher : OUP USA
ISBN 13 : 0195136020
Total Pages : 481 pages
Book Rating : 4.1/5 (951 download)
Download or read book Common Malformations written by Lewis B. Holmes and published by OUP USA. This book was released on 2011-09-29 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative research guide includes over 400 original photographs and illustrations of major malformations, minor abnormalities and birth marks. The book is designed for ease of use and includes a full chapter of anthropologic measurements to help practitioners conduct a diagnostic evaluation and determine the degree of variation and malformation.
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Publisher :
ISBN 13 : 9789241572255
Total Pages : 187 pages
Book Rating : 4.5/5 (722 download)
Download or read book Environmental Health Criteria written by and published by . This book was released on 1976 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yvonne Will
Publisher : John Wiley & Sons
ISBN 13 : 1119053390
Total Pages : 899 pages
Book Rating : 4.1/5 (19 download)
Download or read book Drug Discovery Toxicology written by Yvonne Will and published by John Wiley & Sons. This book was released on 2016-03-22 with total page 899 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
Author : John Timbrell
Publisher : CRC Press
ISBN 13 : 9780748407378
Total Pages : 408 pages
Book Rating : 4.4/5 (73 download)
Download or read book Principles of Biochemical Toxicology, Third Edition written by John Timbrell and published by CRC Press. This book was released on 1999-10-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.
Author : Amanda E.I. Proudfoot
Publisher : Humana
ISBN 13 : 9781617371516
Total Pages : 0 pages
Book Rating : 4.3/5 (715 download)
Download or read book Chemokine Protocols written by Amanda E.I. Proudfoot and published by Humana. This book was released on 2010-11-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemokines family of small proteins are involved in numerous b- logical processes ranging from hematopoiesis, angiogenesis, and basal l- kocyte trafficking to the extravasation and tissue infiltration of leukocytes in response to inflammatory agents, tissue damage, and bacterial or viral infection. Chemokines exert their effects through a family of seven G-protein coupled transmembrane receptors. Worldwide interest in the chemokine field surged dramatically early in 1996, with the finding that certain chemokine receptors were the elusive coreceptors, required along with CD4, for HIV infection. Today, though over 40 human chemokines have been described, the n- ber of chemokine receptors lags behind—only 17 human chemokine receptors have been identified so far. What has emerged over the years is that most chemokine receptors bind several distinct ligands, and indeed the majority of chemokines are able to bind to multiple chemokine receptors, explaining to some extent the apparent disparity in the numbers of chemokines and rec- tors. Yet in spite of the apparent redundancy in chemokine/chemokine rec- tor interactions, it is clear that in vivo, spatial, temporal, and indeed cell- and tissue-specific expression of both chemokines and their receptors are imp- tant factors in determining the precise nature of cellular infiltrates in phy- ological and pathological processes.
Author : T. S. S. Dikshith
Publisher : John Wiley & Sons
ISBN 13 : 0471458775
Total Pages : 659 pages
Book Rating : 4.4/5 (714 download)
Download or read book Industrial Guide to Chemical and Drug Safety written by T. S. S. Dikshith and published by John Wiley & Sons. This book was released on 2003-05-27 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to a wide variety of chemicals and drugs has become common in industrial, laboratory, and even household environments. Fortunately, global understanding and consequently global safety standards regarding the management of toxic and hazardous substances are fast approaching uniformity. The methods of handling, use, transportation, storage, and disposal in particular are moving toward standardization. As these protocols involving chemicals and drugs continue to cross international borders, students and professionals need a reliable resource to ensure they observe appropriate safety standards. The Industrial Guide to Chemical and Drug Safety covers not only current standards, but also a wealth of information on toxins to help regulatory bodies develop new protocols. Written in an accessible narrative style, the Guide covers chemicals by key classes such as solvents, pesticides, and metals, and also by key industries such as drugs, food additives, plastics, cosmetics, detergents, and soaps. The book explains the beneficial and harmful aspects of a broad range of materials to which students, trainees, skilled workers, managers, and personnel associated with regulatory agencies are exposed, with the purpose of helping them avoid the illnesses associated with the misuse of chemicals and drugs. Chapters include: -Heavy Metals -Pesticides -Industrial Solvents -Industrial Gases and Fumes -Drugs -Target Organ Toxicity -Disposal of Hazardous Chemicals -Guidance to Students and Workers -Good Laboratory Practice
Author : Michael Balls
Publisher : Springer Science & Business Media
ISBN 13 : 1461430550
Total Pages : 282 pages
Book Rating : 4.4/5 (614 download)
Download or read book New Technologies for Toxicity Testing written by Michael Balls and published by Springer Science & Business Media. This book was released on 2012-03-22 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment. Of course, many of the techniques and methods described in this volume are in the early stages of development, and much work will be needed to ensure their further improvement, optimisation and validation. However, we are confident that this will be achieved and that, just as with the in vitro assays that were validated and granted regulatory acceptance over the last decade, these, and many other new, advanced methods, will likewise become part of the toxicologist’s improved toolbox for coping with increasingly stringent and numerous regulatory requirements and test chemicals, while placing less reliance on traditional testing paradigms.
Author : Kenneth Kaushansky
Publisher : McGraw Hill Professional
ISBN 13 : 0071833013
Total Pages : 2528 pages
Book Rating : 4.0/5 (718 download)
Download or read book Williams Hematology, 9E written by Kenneth Kaushansky and published by McGraw Hill Professional. This book was released on 2015-12-23 with total page 2528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
Author : Kenneth Hensley
Publisher : Humana Press
ISBN 13 : 9780896038158
Total Pages : 216 pages
Book Rating : 4.0/5 (381 download)
Download or read book Methods in Biological Oxidative Stress written by Kenneth Hensley and published by Humana Press. This book was released on 2003-04-07 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal and abnormal tissue function, it has become imperative to develop appropriate analytical techniques to facilitate the quantitation of significant reactants. Without advances in methodology, corresponding advances in our knowledge of underlying biochemical events will be necessarily limited. Drs. Hensley and Floyd have done an outstanding job of assembling the work of world-class experts into Methods in Biological Oxidative Stress. The contributors have presented concise, yet thorough, descriptions of the state-of-the-art methods that any investigator working in the field needs to access. Mannfred A. Hollinger v Preface Free radicals and reactive oxidizing agents were once ignored as biochemical entities not worth close scrutiny, but are now recognized as causes or contributing factors in dozens, if not hundreds, of disease states. In addition, free radical metabolisms of xenobiotics have become increasingly important to pharmacologists. Accordingly, the need has arisen to accurately quantify reactive oxygen species and their byproducts. Methods in Biological Oxidative Stress is practical in scope, providing the details of up-to-date techniques for measuring oxidative stress and detecting oxidizing agents both in vitro and in vivo. The contributors are recognized experts in the field of oxidative stress who have developed novel strategies for studying biological oxidations.
Author : Teresa Woodruff
Publisher : Springer Science & Business Media
ISBN 13 : 0387722920
Total Pages : 269 pages
Book Rating : 4.3/5 (877 download)
Download or read book Oncofertility written by Teresa Woodruff and published by Springer Science & Business Media. This book was released on 2007-10-30 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past, pregnancy after cancer was largely unheard of. Today, it is increasingly a possibility. Oncofertility has emerged as an interdisciplinary field bridging biomedical and social sciences, and examining issues regarding an individual’s fertility options, choice and goals in light of cancer diagnosis, treatment and survivorship. Written by leaders in this evolving field, the volume covers various aspects: medical, ethical and social.
Author : Ronald Ross Watson
Publisher : CRC Press
ISBN 13 : 0203507630
Total Pages : 448 pages
Book Rating : 4.2/5 (35 download)
Download or read book Nutrition and Alcohol written by Ronald Ross Watson and published by CRC Press. This book was released on 2003-12-17 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, much has been learned about the damaging effects that moderate to severe alcohol use has on tissue nutrient levels and dietary intake. In addition to alcohol's potential to damage every organ in the body, alcohol abuse or heavy use causes poorer dietary intake and provides a greater risk of alcohol's damage while increasing th
Author : Marshall A. Lichtman
Publisher : McGraw Hill Professional
ISBN 13 : 007162242X
Total Pages : 769 pages
Book Rating : 4.0/5 (716 download)
Download or read book Williams Manual of Hematology, Eighth Edition written by Marshall A. Lichtman and published by McGraw Hill Professional. This book was released on 2011-05-31 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: A full-color quick reference distilled from the world's leading hematology text
Author : Carlos M. Palmeira
Publisher :
ISBN 13 : 9781071610916
Total Pages : 266 pages
Book Rating : 4.6/5 (19 download)
Download or read book Toxicity Assessment written by Carlos M. Palmeira and published by . This book was released on 2021 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.
Author : Roland T. Skeel
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 160831782X
Total Pages : 896 pages
Book Rating : 4.6/5 (83 download)
Download or read book Handbook of Cancer Chemotherapy written by Roland T. Skeel and published by Lippincott Williams & Wilkins. This book was released on 2011 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Skeel's Handbook of Cancer Chemotherapy combines in one place the most current rationale and specific details necessary to safely administer chemotherapy for most adult cancers. The handbook is a practical, diseased-focused pocket reference that emphasizes the best current medical practice as it relates to the delivery of chemotherapeutic drugs. By focusing on specific plans for treatment, the book is an invaluable resource for the daily care of cancer patients.
Author : Pritam S. Sahota
Publisher : CRC Press
ISBN 13 : 1439872120
Total Pages : 987 pages
Book Rating : 4.4/5 (398 download)
Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2013-04-09 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Saf
