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The Role Of Products Of The Histocompatibility Gene Complex In Immune Responses
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Book Synopsis The Role of Products of the Histocompatibility Gene Complex in Immune Responses by : David H. Katz
Download or read book The Role of Products of the Histocompatibility Gene Complex in Immune Responses written by David H. Katz and published by Academic Press. This book was released on 2014-06-28 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Role of Products of the Histocompatibility Gene Complex in Immune Responses documents the proceedings of a conference held on 3-7 November 1975, which brought together an international group of scientists spanning three independent disciplines—genetics and immunogenetics, molecular biochemistry, and immunobiology—with clinical medicine overlapping these disciplines. This volume contains 42 papers organized according to the eight sessions held at the conference. The papers in Session I examined the genetics of the major histocompatibility complex. Session II presented studies on the biology of mixed lymphocyte interactions and cell-mediated cytotoxicity reactions. Session III discussed immune response gene systems while Session IV dealt with the genetic control of cell interactions. The papers in Session V covered idiotypic determinants on T cell receptors. Session VI investigated the properties of histocompatibility gene products involved in regulation of immune responses. Session VII focused on the biochemistry and immunocytology of cell surface products of the major histocompatibility complex. Finally, Session VIII discussed interrelationships between products of the major histocompatibility complex and their relevance to disease.
Book Synopsis The Role of Products of the Histocompatibility Gene Complex in Immune Responses by : David H. Katz
Download or read book The Role of Products of the Histocompatibility Gene Complex in Immune Responses written by David H. Katz and published by . This book was released on 1976 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunogenetics by : Gabriel S Panayi
Download or read book Immunogenetics written by Gabriel S Panayi and published by Butterworth-Heinemann. This book was released on 2014-05-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunogenetics is a 12-chapter book that begins with the elucidation of the major histocompatibility complex genes and their role in autoimmune and infectious diseases. Subsequent chapters explore the human major histocompatibility complex, including implications of their complement genes for linkage disequilibrium and disease associations. This book also describes the genetics of human immunoglobulins; T-cell clones; genes of the major histocompatibility complex of the mouse; and the generation, characterization, and use of monoclonal antibodies of murine and human origin. Specific diseases are also discussed; these include spondoarthritides, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and autoimmune thyroid disease. This book will be of beneficial value to specialists in infectious diseases, endocrinology, connective tissue diseases, and neurology, as well as to medical scientists in immunology and molecular biology.
Book Synopsis Cell Biology of the Major Histocompatibility Complex by : Benvenuto Pernis
Download or read book Cell Biology of the Major Histocompatibility Complex written by Benvenuto Pernis and published by Elsevier. This book was released on 2012-12-02 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology of the Major Histocompatibility Complex documents the proceedings of a symposium on ""Cell Biology of the Major Histocompatibility Complex"" held at Arden House on the Harriman Campus of Columbia University from June 8 -10, 1984. The meeting was the ninth of the P & S Biomedical Sciences Symposia. The book is organized into five parts. Part I on the structure of MHC molecules includes papers on human histocompatibility antigens; the cloning of human MHC; and organization of the genes of the H-2 complex. Part II on alternate forms of MHC molecules includes studies on the expression of a secreted form of the MHC class I antigen and alternative splicing in the H-2 multigene family. Part III deals with MHC biosynthesis, intracellular transport, and membrane expression. It includes studies on the manipulation of glycans on antigens of the MHC and dynamics of MHC molecules in lymphoid cells. Part IV on homologues of class I MHC molecules covers topics such as Tla expression in normal and malignant cells and the Qa series of antigens. Part V on the association of MHC with antigens includes studies such as histocompatibility molecules as immune response gene products and molecular nature of T-cell recognition of antigen.
Book Synopsis HLA and MHC by : Michael J. Browning
Download or read book HLA and MHC written by Michael J. Browning and published by Taylor & Francis. This book was released on 1996 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of the major histocompatibility complex (MHC), and the role it plays in the immune response and in disease. The emphasis throughout is on the human MHC, but relevant animal studies are inclded to give a comprehensive review of the subject.
Book Synopsis Histocompatibility by : George Snell
Download or read book Histocompatibility written by George Snell and published by Elsevier. This book was released on 2012-12-02 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histocampatibility covers the genetic, immunologic, and the chemical studies on allograft rejection process. The book is composed of 13 chapters that describe how these studies relate to medicine, organ transplantation in man, basic immunology, cell membrane structures, and cancer research. After briefly dealing with the early studies on isografts and allografts in laboratory animals, the book describes the histogenetic methods of gene manipulation and transplantation that permit identification of individual histocompatibility loci. The following chapter examines the significance of congenic resistant lines in determining the diversity of histocompatibility loci and allele and immune response genes. Other chapters present immunogenetic and serological methods, as well as the applications of these methods in studying alloantigens and H-2 complex loci and of immunogenetic methods to human. The book also discusses the practical implication of HLA immunogenetics in organ transplantation and describes the biochemical, immunochemical, and dynamic properties of alloantigens. A chapter discusses the associations between HLA system and disease and the various mechanisms that have been suggested to explain these associations. The last chapter focuses on allograft reaction and on established facts of cellular immunity. This book is a valuable source of information for researchers in the fields of medicine, organ transplantation in man, basic immunology, cell membrane structures, and cancer.
Book Synopsis The Role of the Major Histocompatibility Complex in Immunobiology by : Martin E. Dorf
Download or read book The Role of the Major Histocompatibility Complex in Immunobiology written by Martin E. Dorf and published by Scholarly Title. This book was released on 1981 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The HLA System written by John Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume documents our growing understanding of the human major histocompatibility complex. The application of this information is ever more important as the limits of transplantation continue to be reduced, including the recent success of bone marrow transplantation between unrelated but closely matched individuals. In addition, the need to transfuse platelets in the face of immunologic barriers continues to challenge transfusion services. Thus, the serologic information summarized in this volume is essential for optimal patient care. At the same time, recombinant DNA technology has led to a revolution in our understanding of many aspects of basic biology. Among the advances has been the initial characterization of the structure of some HLA loci. While this will ultimately improve clinical services, constant reference to serologic data is essential so that the powerful new techniques can be applied in the most effective ways. The timing of the First Red Cross International Histocompatibility Workshop is fortunate as it brings together experts from around the world to address the state of the art. We are all grateful to Dr. John Lee and his colleagues for organizing the workshop, and for bringing together in this volume the material to be presented in Beijing during October 17-23, 1990. Leon W. Hoyer, M.D.
Book Synopsis Handbook of Immune Response Genes by : Tak W. Mak
Download or read book Handbook of Immune Response Genes written by Tak W. Mak and published by Springer Science & Business Media. This book was released on 2007-07-27 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of immunology encompasses a vast and ever-growing body of information that in some way or other incorporates most areas of medical biological research. As the body of information in the medical sciences continues to increase its rate of expansion, one of the greatest challenges to investigators will be to integrate this information in a manner that is intellectually fruitful and productive. Considering the intended scope of this text, we could not pretend to have gone too far toward achieving such an integration--and considering the pace of change, in its very best form a measured approximation of such lofty goals might be the most we could hope for. Nevertheless, in these pages we have sought to produce a collection of information that is at once concise and up-to-date regarding areas where important developments are impacting on the way we understand the vertebrate immune system. In addition, although the information is geared toward advanced study, we have discussed some basic elements and concepts that we hope make the text a useful resource for both the immunologist and the nonspecialist. The intention is to provide the researcher, clinician, or advanced undergraduate student with a brief ov- view of specific components of the immune system, and to provide a place from which to begin further detailed study if necessary. To this end, we made every effort to supply extensive referencing--although limitations in space prevented exhaustive or complete referencing in some cases.
Book Synopsis In Silico Immunology by : Darren D.R. Flower
Download or read book In Silico Immunology written by Darren D.R. Flower and published by Springer Science & Business Media. This book was released on 2007-04-16 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines three emergent disciplines, which are now poised to engineer a paradigm shift from hypothesis- to data-driven research: theoretical immunology, immunoinformatics, and Artificial Immune Systems. It details how these disciplines will enable new understanding to emerge from the analysis of complex datasets. Coverage shows how these three are set to transform immunological science and the future of health care.
Book Synopsis The HLA Complex in Biology and Medicine by : Narinder K Mehra
Download or read book The HLA Complex in Biology and Medicine written by Narinder K Mehra and published by Boydell & Brewer Ltd. This book was released on 2010-11-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.
Book Synopsis The Major Histocompatibility Complex Region of Domestic Animal Species by : Lawrence B. Schook
Download or read book The Major Histocompatibility Complex Region of Domestic Animal Species written by Lawrence B. Schook and published by CRC Press. This book was released on 1996-08-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major histocompatibility complex (Mhc) is one of the few identified gene systems in domestic animals that is associated with quantitative traits such as disease resistance, immune response, growth, and reproduction. As knowledge of this important system increases, we move closer toward the reality of genetic enhancement of animal welfare and production efficiency. This book represents the current state of knowledge on the Mhc of agriculturally important animals and explores the latest advances in technology. For the first time, the unique findings of recent Mhc research are presented in a single source. The Major Histocompatibility Complex Region of Domestic Animal Species begins with a discussion of the evolution of Mhc. The chapters are then organized with respect to specific species, with a chapter devoted to each. The Mhc of mice and humans are used as a common reference for comparisons between diverse species. The text concludes with a look at future strategies and directions in Mhc research. Comparative immunologists and geneticists, veterinarians, animal breeders, researchers, and university and postgraduate students will all benefit from this detailed look at the evolution, structure, and organization of Mhc.
Book Synopsis Improving Genetic Disease Resistance in Farm Animals by : Akke Jitske Akkermans
Download or read book Improving Genetic Disease Resistance in Farm Animals written by Akke Jitske Akkermans and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics". The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.
Book Synopsis Modulation of MHC Antigen Expression and Disease by : G. Eric Blair
Download or read book Modulation of MHC Antigen Expression and Disease written by G. Eric Blair and published by Cambridge University Press. This book was released on 1995-11-09 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major histocompatibility complex (MHC) genes are involved in the immune system's response to tumor and infected cells and in generating an immune response. This book brings together basic aspects of the regulation of MHC antigens with important clinical applications (in viral infection, viral oncology, cancer biology and autoimmunity). There is a strong emphasis on situations where MHC expression is modulated (either stimulated or repressed). The book's major themes are: the mechanisms of MHC expression--explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of cytokines on MHC expression--both in the etiology of certain diseases and in possible immunotherapeutic approaches to disease; and the use of gene therapy to modify MHC expression in cancer cells, and thereby cause tumor rejection. This book will be valuable to researchers and clinicians in molecular biology, immunology, oncology, and virology.
Book Synopsis Evolution of the House Mouse by : Miloš Macholán
Download or read book Evolution of the House Mouse written by Miloš Macholán and published by Cambridge University Press. This book was released on 2012-07-19 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The house mouse is the source of almost all genetic variation in laboratory mice; its genome was sequenced alongside that of humans, and it has become the model for mammalian speciation. Featuring contributions from leaders in the field, this volume provides the evolutionary context necessary to interpret these patterns and processes in the age of genomics. The topics reviewed include mouse phylogeny, phylogeography, origins of commensalism, adaptation, and dynamics of secondary contacts between subspecies. Explorations of mouse behaviour cover the nature of chemical and ultrasonic signalling, recognition, and social environment. The importance of the mouse as an evolutionary model is highlighted in reviews of the first described example of meiotic drive (t-haplotype) and the first identified mammalian speciation gene (Prdm9). This detailed overview of house mouse evolution is a valuable resource for researchers of mouse biology as well as those interested in mouse genetics, evolutionary biology, behaviour, parasitology, and archaeozoology.
