Role of Insulin Resistance in the Pathogenesis and Treatment of Noninsulin Dependent Diabetes Mellitus

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (498 download)

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Book Synopsis Role of Insulin Resistance in the Pathogenesis and Treatment of Noninsulin Dependent Diabetes Mellitus by : Upjohn Company

Download or read book Role of Insulin Resistance in the Pathogenesis and Treatment of Noninsulin Dependent Diabetes Mellitus written by Upjohn Company and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Role of Insulin Resistance in the Pathogenesis and Treatment of Noninsulin-dependent Diabetes Mellitus

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ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.:/5 (248 download)

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Book Synopsis The Role of Insulin Resistance in the Pathogenesis and Treatment of Noninsulin-dependent Diabetes Mellitus by :

Download or read book The Role of Insulin Resistance in the Pathogenesis and Treatment of Noninsulin-dependent Diabetes Mellitus written by and published by . This book was released on 1983 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pathogenesis and Treatment of Diabetes Mellitus

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Publisher : Springer Science & Business Media
ISBN 13 : 9400943016
Total Pages : 182 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Pathogenesis and Treatment of Diabetes Mellitus by : J.K. Radder

Download or read book Pathogenesis and Treatment of Diabetes Mellitus written by J.K. Radder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book on diabetes mellitus both the pathogenesis and treat ment of the disease will be discussed. Pathogenetic studies have led to the distinction between type I and type II diabetes. In type I hyperglycaemia is due predominantly to insulin deficiency; in type II insulin resistance is more important. Three pathogenetic factors are thought to play a role in the etiol ogy of type I diabetes: heredity, viral infections and immunity. There may be a relationship between these three aspects since genetic pre disposition changes the susceptibility to viral infections and/or the immunological defence against these infections. Insulitis ensues. Auto immune processes initiated by this chain of events may contribute to the destruction of the B cells in the islets of Langerhans and diabetes -may eventually follow. This means that at the time of the sudden out break of the disease, the destructive process has already been active for years.

New Concepts in the Pathogenesis of NIDDM

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Publisher : Springer Science & Business Media
ISBN 13 : 1461529107
Total Pages : 314 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis New Concepts in the Pathogenesis of NIDDM by : Claes-Goran Östenson

Download or read book New Concepts in the Pathogenesis of NIDDM written by Claes-Goran Östenson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) has attracted the interest of our group during the last three decades. As early as 1969, a Nobel Symposium dealing with this topic was organized in Stockholm. This was followed in 1987 by a Nobel Conference devoted to the same subject. The main purpose of these meetings was to bring together the most distinguished scientists from all over the world and present theories on molecular and genetic mechanisms responsible for the development of glucose intolerance in NIDDM. This idea was followed also in the present symposium, "New Concepts in the Pathogenesis of NIDDM," organized with diabetologists from Toronto in Canada. Our purpose is to biannually organize international meetings covering important aspects of dia betes research, hoping that this type of interaction may result in new concepts and treat ment alternatives. For us, participating in this symposium in September 1992, the meeting in Stockholm was very stimulating and innovative. It is a special pleasure that almost all invited lecturers submitted manuscripts. Thus, the publication of the proceedings of the symposium makes it possible for all interested in diabetes research to share new ideas and findings presented at the meeting. Claes-G6ran Ostenson Suad Efendic Mladen V ranic v CONTENTS REGULATION OF INSULIN SECRETION Impaired Glucose-Induced Insulin Secretion: Studies in Animal Models with Spontaneous NIDDM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . C. -G. Ostenson, A. Khan, and S. Efendic Perturbation ofIslet Metabolism and Insulin Release in NIDDM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 WJ. Malaisse 2 Regulation of Cytoplasmic Free Ca+ in Insulin-Secreting Cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Proceedings of a Symposium

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Publisher :
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.:/5 (251 download)

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Book Synopsis Proceedings of a Symposium by :

Download or read book Proceedings of a Symposium written by and published by . This book was released on 1983 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinician's Guide to Non-insulin-dependent Diabetes Mellitus

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Publisher :
ISBN 13 : 9780824782986
Total Pages : 166 pages
Book Rating : 4.7/5 (829 download)

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Book Synopsis Clinician's Guide to Non-insulin-dependent Diabetes Mellitus by : Gerald M. Reaven

Download or read book Clinician's Guide to Non-insulin-dependent Diabetes Mellitus written by Gerald M. Reaven and published by . This book was released on 1989 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetes Mellitus in Children

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Publisher :
ISBN 13 : 9781416027539
Total Pages : 0 pages
Book Rating : 4.0/5 (275 download)

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Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

International Textbook of Diabetes Mellitus

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Publisher : John Wiley & Sons
ISBN 13 : 1118387678
Total Pages : 1200 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis International Textbook of Diabetes Mellitus by : R. A. DeFronzo

Download or read book International Textbook of Diabetes Mellitus written by R. A. DeFronzo and published by John Wiley & Sons. This book was released on 2015-03-11 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.

Insulin Resistance

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Publisher : John Wiley & Sons
ISBN 13 : 9780471939771
Total Pages : 446 pages
Book Rating : 4.9/5 (397 download)

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Book Synopsis Insulin Resistance by : David Moller

Download or read book Insulin Resistance written by David Moller and published by John Wiley & Sons. This book was released on 1993-10-15 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past two decades have seen explosive gains in our understanding of the physiology and basic mechanisms of insulin action and the critical importance of insulin resistance in the pathogenesis of clinical disorders such as non-insulin dependent diabetes mellitus, essential hypertension and atherosclerotic cardiovascular disease. Insulin Resistance offers the first comprehensive review of the field, with integrated chapters providing up to date coverage of the essential components of basic and clinical research that have contributed to current understanding of the topic. There are chapters on basic mechanisms of insulin action, in depth discussions of insulin resistance syndromes from epidemiological, clinical and biochemical viewpoints and a discussion of therapeutic approaches to insulin resistance. Insulin Resistance will be an invaluable resource for clinicians and scientists with an interest in the mechanisms of insulin action, the clinical sequelae of hyperinsulinemia and future therapies of insulin resistance.

Pathogenesis and New Approaches to the Study of Noninsulin-dependent Diabetes Mellitus

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Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pathogenesis and New Approaches to the Study of Noninsulin-dependent Diabetes Mellitus by : Albert Y. Chang

Download or read book Pathogenesis and New Approaches to the Study of Noninsulin-dependent Diabetes Mellitus written by Albert Y. Chang and published by . This book was released on 1988 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pathogenesis of Non-insulin Dependent Diabetes Mellitus

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ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pathogenesis of Non-insulin Dependent Diabetes Mellitus by : Valdemar Grill

Download or read book Pathogenesis of Non-insulin Dependent Diabetes Mellitus written by Valdemar Grill and published by . This book was released on 1988 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetes Mellitus: Pathophysiology and Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642742556
Total Pages : 399 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Diabetes Mellitus: Pathophysiology and Therapy by : Werner Creutzfeldt

Download or read book Diabetes Mellitus: Pathophysiology and Therapy written by Werner Creutzfeldt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the reviews delivered at the Bayer Centenary Symposium held in Edinburg in May 1988. Experts in the field reported on recent developments in the pathophysiology and therapy of diabetes mellitus. Thus an up-to-date overview of diabetes mellitus research presented to a small group of specialists is now available to a broader community of endocrinologists, physicians and internists.

Insulin Resistance

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Publisher : Springer Science & Business Media
ISBN 13 : 9780896035881
Total Pages : 388 pages
Book Rating : 4.0/5 (358 download)

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Book Synopsis Insulin Resistance by : Gerald M. Reaven

Download or read book Insulin Resistance written by Gerald M. Reaven and published by Springer Science & Business Media. This book was released on 1999-04 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.

An Atlas of Diabetes Mellitus, Second Edition

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Publisher : CRC Press
ISBN 13 : 1842140094
Total Pages : 104 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis An Atlas of Diabetes Mellitus, Second Edition by : Ian N. Scobie

Download or read book An Atlas of Diabetes Mellitus, Second Edition written by Ian N. Scobie and published by CRC Press. This book was released on 2004-09-23 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated An Atlas of Diabetes Mellitus, Second Edition provides complete coverage on the signs and symptoms of diabetes mellitus and its treatment. The atlas features over 100 color plates illustrating the signs and symptoms of insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM) and their treatment. The book contains an instructive review section that covers IDDM and NIDDM pathogenesis; treatments with diet, insulin, and drugs; acute complications of hypoglycemia, diabetic ketoacidosis, and hyperosmolar non-ketoacidotic coma; chronic complications of diabetic retinopathy, nephropathy, and neuropathy, major vascular disease, hypertension, and the diabetic foot; and diabetes and pregnancy. Detailed captions for each illustration enhance the book's value as an atlas-text for teaching, residency training, and clinical practice. Includes bibliographic references and index.

Insulin Resistance

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Publisher : John Wiley & Sons
ISBN 13 : 0470698381
Total Pages : 202 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Insulin Resistance by : Andrew Krentz

Download or read book Insulin Resistance written by Andrew Krentz and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insulin resistance, defined as a reduced biological action of insulin, has emerged as a major factor in the development and progression of a number of common non-communicable diseases in man. The role of insulin resistance in the aetiology of type 2 diabetes is particularly well-established. However, insulin resistance has also come to be regarded as a key component of a broader syndrome of common metabolic defects that conspire to increase the risk of atherosclerotic coronary heart disease. The ramifications of insulin resistance now embrace many different medical specialties. The objective of this book is to summarize the current state of knowledge about insulin resistance. Section 1 (Pathophysiology of Insulin Resistance) considers the development of current concepts of insulin resistance. This is followed by a critical review of techniques for the assessment of insulin action in humans. The section concludes with an outline of current hypotheses concerning the molecular defects responsible for insulin resistance. Section 2 (Insulin Resistance in Clinical Medicine) broadens the discussion to include physiological and pathological conditions with which insulin resistance is associated; the effects of drug treatment on insulin sensitivity are also considered. Section 3 (Management of Insulin Resistance and Associated Conditions) focuses on the avoidance and treatment of insulin resistance in its clinical manifestations. A discussion of the potential benefits of non-pharmacological measures prefaces a review of the range of drugs used in the treatment of type 2 diabetes and related disorders. References are confined to key articles at the end of each section. Improved nutrition allied to increased levels of physical exercise are of crucial importance in the battle to stem the increasing incidence and prevalence of insulin resistance; however, translation of such advice into action has proved difficult in practice. Thus, other approaches have been explored. Recent years have witnessed considerable progress in the pharmacological management of insulin resistance. In particular, the thiazolidinediones (and other insulin-sensitizing drugs) appear to provide a more specific assault on insulin-resistance. Clinical experience with these agents remains relatively limited and serious hepatotoxicity has clouded the first agent in this class - troglitazone. With its introduction into the USA in 1995 and driven by the publication of the United Kingdom Prospective Diabetes Study, metformin has enjoyed a renaissance. This well-established agent is finding application for new clinical indications. In parallel, the development of anti-obesity drugs continues apace. The molecular and genetic mechanisms underlying some forms of insulin resistance are being revealed. Original intellectual concepts such as the fetal origins hypothesis are challenging traditional views about the aetiology of insulin resistance and its clinical sequelae. These exciting scientific advances notwithstanding, the evolving global epidemic of obesity and type 2 diabetes represents an enormous public health challenge. Now more than ever, research must focus on identifying solutions that are applicable on the level of entire populations. By definition, these must also be practical and cost-effective.

Polycystic Ovary Syndrome

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Publisher : Springer Science & Business Media
ISBN 13 : 1597451088
Total Pages : 361 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Polycystic Ovary Syndrome by : Andrea Dunaif

Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Clinician's Guide to Non-Insulin-Dependent Diabetes Mellitus

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Publisher :
ISBN 13 : 9780598039347
Total Pages : 149 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Clinician's Guide to Non-Insulin-Dependent Diabetes Mellitus by : Gerald M. Reaven

Download or read book Clinician's Guide to Non-Insulin-Dependent Diabetes Mellitus written by Gerald M. Reaven and published by . This book was released on with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: