The Recent Topics in Genetic Polymorphisms

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Publisher : BoD – Books on Demand
ISBN 13 : 1789858917
Total Pages : 149 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis The Recent Topics in Genetic Polymorphisms by : Mahmut Çalışkan

Download or read book The Recent Topics in Genetic Polymorphisms written by Mahmut Çalışkan and published by BoD – Books on Demand. This book was released on 2020-05-13 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book in your hands presents chapters revealing the magnitude of genetic polymorphisms that exist in different kinds of living beings. Natural populations contain a considerable amount of genetic change, which provides a genomic flexibility that can be used as a raw material for adaptation to changing environmental conditions. The analysis of genetic polymorphisms provides information about DNA sequence changes at a given locus. The increasing availability of PCR-based molecular markers allows for the detailed analyses and the detection of genetic changes influencing some important traits. The purpose of this book is to provide a glimpse into the dynamic process of genetic polymorphisms by presenting the thoughts of scientists engaged in the generation of new ideas and techniques employed for the assessment of genetic polymorphisms. The book should prove useful to students, researchers and experts in the area of molecular genetics.

Genetic Polymorphisms

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Publisher : BoD – Books on Demand
ISBN 13 : 1839688106
Total Pages : 226 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Genetic Polymorphisms by : Mahmut Çalışkan

Download or read book Genetic Polymorphisms written by Mahmut Çalışkan and published by BoD – Books on Demand. This book was released on 2022-05-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.

Genetic Polymorphisms

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Publisher : BoD – Books on Demand
ISBN 13 : 9535135155
Total Pages : 282 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Genetic Polymorphisms by : Narasimha Reddy Parine

Download or read book Genetic Polymorphisms written by Narasimha Reddy Parine and published by BoD – Books on Demand. This book was released on 2017-09-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.

Genetic Polymorphism and cancer susceptibility

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Publisher : Springer Nature
ISBN 13 : 9813366990
Total Pages : 353 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Genetic Polymorphism and cancer susceptibility by : Aga Syed Sameer

Download or read book Genetic Polymorphism and cancer susceptibility written by Aga Syed Sameer and published by Springer Nature. This book was released on 2021-04-22 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

Genetic Polymorphisms and Susceptibility to Disease

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Publisher : CRC Press
ISBN 13 : 9780748408221
Total Pages : 298 pages
Book Rating : 4.4/5 (82 download)

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Book Synopsis Genetic Polymorphisms and Susceptibility to Disease by : Mark Steven Miller

Download or read book Genetic Polymorphisms and Susceptibility to Disease written by Mark Steven Miller and published by CRC Press. This book was released on 2000-04-27 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but thorough overview of how allelic gene differences influence disease susceptibility in the human population, and will be a useful reference to researchers across a range of disciplines, for example, oncology, cardiology and immunology . In addition, this book serves as a primer for students first entering the field of genetic research.

Genetic Diversity and Disease Susceptibility

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Publisher : BoD – Books on Demand
ISBN 13 : 1789842018
Total Pages : 166 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Genetic Diversity and Disease Susceptibility by : Yamin Liu

Download or read book Genetic Diversity and Disease Susceptibility written by Yamin Liu and published by BoD – Books on Demand. This book was released on 2018-10-17 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.

Genes, Polymorphisms, and the Making of Societies

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Publisher : Universal-Publishers
ISBN 13 : 1627343458
Total Pages : 214 pages
Book Rating : 4.6/5 (273 download)

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Book Synopsis Genes, Polymorphisms, and the Making of Societies by : Hippokratis Kiaris

Download or read book Genes, Polymorphisms, and the Making of Societies written by Hippokratis Kiaris and published by Universal-Publishers. This book was released on 2021-06-15 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our genes determine to a large extent who we are and why we are different from others. In this book, Hippokratis Kiaris explores how various genetic polymorphisms in different ethnic populations may affect the development of distinct cultures and eventually historical decisions. It should be read by anybody interested in history, anthropology, behavior, psychology or genetics. The reader will find clues linking together these scientific disciplines and how such genetically determined behavioral traits may play an undervalued, as yet, role in shaping historical outcomes. The book initially describes some basic concepts on genetics and proceeds with an outline of human evolution, the journey of early humans Out-of-Africa, and the colonization of Earth by different human populations that eventually resulted in the development of different cultures. Then, by focusing on the two major prototype cultural lines, the Eastern and the Western, the author discusses differences in the corresponding civilizations in view of specific genetic polymorphisms that affect behavior and differ in frequencies between people of Asian and European origin. Finally, in view of the contemporary increasing tendency for cultural globalization, the book attempts to predict future trends on cultures and behavioral patterns. In this revised and extended second edition new data are included and new chapters, focusing on how sets of genes, as opposed to individual ones, coexist in different populations and may potentially impact cultural divergence throughout history.

Single Nucleotide Polymorphisms

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Publisher : Humana Press
ISBN 13 : 9781617796791
Total Pages : 464 pages
Book Rating : 4.7/5 (967 download)

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Book Synopsis Single Nucleotide Polymorphisms by : Anton A. Komar

Download or read book Single Nucleotide Polymorphisms written by Anton A. Komar and published by Humana Press. This book was released on 2012-02-25 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field.

Transporters and Drug-Metabolizing Enzymes in Drug Toxicity

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Publisher : John Wiley & Sons
ISBN 13 : 1119170842
Total Pages : 530 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Transporters and Drug-Metabolizing Enzymes in Drug Toxicity by : Albert P. Li

Download or read book Transporters and Drug-Metabolizing Enzymes in Drug Toxicity written by Albert P. Li and published by John Wiley & Sons. This book was released on 2021-07-27 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: TRANSPORTERS AND DRUG-METABOLIZING ENZYMES IN DRUG TOXICITY Explore up-to-date coverage on the interaction between drug metabolism enzymes, transporters, and drug toxicity with this leading resources Transporters and Drug-Metabolizing Enzymes in Drug Toxicity delivers a comprehensive and updated review of the relationship between drug metabolism, transporters, and toxicity, providing insights into a major challenge in drug development – accurate assessment of human drug toxicity. Combining two disciplines frequently considered independently of one another, the book combines drug metabolism and toxicology with a focus on the role of biotransformation on drug toxicity and as a major factor for species and individual differences. Mechanism and species differences in drug metabolizing enzymes and transporters are discussed, as are the methods used to investigate the role of drug metabolizing enzymes and transporters in drug toxicity. Finally, the distinguished authors describe promising new experimental approaches to accurately assessing human drug toxicity via the consideration of human-specific drug metabolism in toxicity assays. In addition to topics as diverse as extended clearance models, experimental approaches for the estimation of DILI potential of drug candidates and roles of transporters in renal drug toxicity, readers will also enjoy the inclusion of such subjects as: A thorough overview of and introduction to drug metabolism and transporters and drug toxicity An exploration of drug metabolism enzymes and transporter activities as risk factors of marketed drugs associated with drug-induced fatalities A discussion of human-based in vitro experimental models for the evaluation of metabolism-dependent drug toxicity A treatment of mechanism-based experimental models for the evaluation of BSEP inhibition and DILI An examination of transporters and cochlea toxicity Perfect for scientists, students, and practitioners with interests in metabolism, toxicology, and drug development in the pharmaceutical industry, Transporters and Drug-Metabolizing Enzymes in Drug Toxicity will also earn a place in the libraries of medicinal chemists, pharmacologists, biochemists, toxicologists, and regulators in the pharmaceutical and health industries.

Single Nucleotide Polymorphisms

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Publisher : Springer Science & Business Media
ISBN 13 : 1592593275
Total Pages : 276 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Single Nucleotide Polymorphisms by : Pui-Yan Kwok

Download or read book Single Nucleotide Polymorphisms written by Pui-Yan Kwok and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.

Genetic Diversity in Plants

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Publisher : Springer Science & Business Media
ISBN 13 : 1468428861
Total Pages : 493 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Genetic Diversity in Plants by : Amir Muhammed

Download or read book Genetic Diversity in Plants written by Amir Muhammed and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the last eighteen years we have been deeply involved in a cooperative effort with our Latin American colleagues in genetics, biochemistry, physiology, and molecular biology. We have been in close contact with scientists in a number of centers and have helped to organize symposia, workshops, and so forth, in an effort to accelerate their development and make their substantial work known. These symposia in Latin America have been quite successful. The fifteenth will take place in Brasilia in 1977. At the request of colleagues, we are in the process of developing a similar series in Asia. The first very successful symposium was held in Calcutta in 1973. We were most pleased when Dr. Amir Muhammed, Vice Chancellor of the University of Agriculture, Lyallpur suggested that we hold a symposium on a topic of great importance to Pakistan, Genetic Control of Diversity in Plants, under the auspices of the University of Agriculture. It is our hope that this symposium will be followed by additional ones in Pakistan as well as in other countries in the Far East. Leadership is quickly developing in the hands of outstanding scientists in these countries, and we appreciate the opportunity to cooperate with them. We are especially grateful to the Natiohal Science Foundation for makingPL- 480 funds available which made this symposium possible.

Tandem Repeat Polymorphisms

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Publisher : Springer Science & Business Media
ISBN 13 : 1461454344
Total Pages : 208 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Tandem Repeat Polymorphisms by : Anthony J. Hannan

Download or read book Tandem Repeat Polymorphisms written by Anthony J. Hannan and published by Springer Science & Business Media. This book was released on 2013-07-30 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease. There are hundreds of thousands of unique tandem repeats in the human genome and their polymorphic distributions have the potential to greatly influence functional diversity and disease susceptibility. Recent discoveries in this expanding field are critically reviewed and discussed in a range of subsequent chapters, with a focus on the role of TRPs and their various gene products in evolution, development, diverse molecular and cellular processes, brain function and disease.

Genetic Variation and Its Maintenance

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Publisher : Cambridge University Press
ISBN 13 : 9780521332576
Total Pages : 318 pages
Book Rating : 4.3/5 (325 download)

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Book Synopsis Genetic Variation and Its Maintenance by : Derek Frank Roberts

Download or read book Genetic Variation and Its Maintenance written by Derek Frank Roberts and published by Cambridge University Press. This book was released on 1986-10-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume considers the genetic variability of human populations, particularly in the tropics: its origins and maintenance, and its contribution to the phenotypic variability of complex characters. The first section deals with the ways of analysing genetic variation and provides a valuable review of relevant developments in molecular biology. The origin and maintenance of genetic diversity is considered in the second section with data presented for Pacific, African, Asian and Central American populations. The final section concerns characters in which the genetic contribution to variability is complex and shows how such characters may be used to elucidate biological problems of affinity and differentiation, of adaptation and survival. Published as part of the Decade of the Tropics research programme of the International Union of Biological Sciences, this volume will be of particular interest to human geneticists, physical and biological anthropologists.

Evaluating Human Genetic Diversity

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Publisher : National Academies Press
ISBN 13 : 0309184746
Total Pages : 101 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Evaluating Human Genetic Diversity by : National Research Council

Download or read book Evaluating Human Genetic Diversity written by National Research Council and published by National Academies Press. This book was released on 1998-01-19 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

Insect life-cycle polymorphism

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Publisher : Springer Science & Business Media
ISBN 13 : 9401718881
Total Pages : 383 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Insect life-cycle polymorphism by : H.V. Danks

Download or read book Insect life-cycle polymorphism written by H.V. Danks and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have shown that genetic polymorphisms play an important role in structuring the seasonal life cycles of insects, complementing an earlier emphasis on the effects of environmental factors. This book presents current ideas and recent research on insect life--cycle polymorphism in a series of carefully prepared chapters by international experts, covering the full breadth of the subject in order to give an up-to-date view of how life cycles are controlled and how they evolve. By consolidating our view of insect life--cycle polymorphism in this way, the book provides a staging point for further enquiries. The volume will be of interest to a wide variety of entomologists and other biologists interested in the control and evolution of life cycles and in understanding the extraordinarily complex ecological strategies of insects and other organisms.

Association Mapping in Plants

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Publisher : Springer Science & Business Media
ISBN 13 : 0387360115
Total Pages : 290 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Association Mapping in Plants by : Nnadozie C. Oraguzie

Download or read book Association Mapping in Plants written by Nnadozie C. Oraguzie and published by Springer Science & Business Media. This book was released on 2007-01-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.

Genetic Polymorphism and Disease

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Publisher : CRC Press
ISBN 13 : 9781032159058
Total Pages : 0 pages
Book Rating : 4.1/5 (59 download)

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Book Synopsis Genetic Polymorphism and Disease by : Syed Sameer Aga

Download or read book Genetic Polymorphism and Disease written by Syed Sameer Aga and published by CRC Press. This book was released on 2022-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases"--